Large Cell Neuroendocrine Carcinoma Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C1265996
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Genes

89 genes associated with the disease Large Cell Neuroendocrine Carcinoma in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ADGRB3 adhesion G protein-coupled receptor B3
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALK anaplastic lymphoma receptor tyrosine kinase
APC adenomatous polyposis coli
APOA1 apolipoprotein A-I
AR androgen receptor
ASCL1 achaete-scute family bHLH transcription factor 1
BCL2 B-cell CLL/lymphoma 2
BDNF brain-derived neurotrophic factor
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
CCND1 cyclin D1
CD274 CD274 molecule
CD99 CD99 molecule
CDKN2A cyclin-dependent kinase inhibitor 2A
CDX2 caudal type homeobox 2
CHGA chromogranin A
CKAP4 cytoskeleton-associated protein 4
CKB creatine kinase, brain
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DLL3 delta-like 3 (Drosophila)
EGFR epidermal growth factor receptor
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
ENO2 enolase 2 (gamma, neuronal)
ENO3 enolase 3 (beta, muscle)
EPHA3 EPH receptor A3
EPHB1 EPH receptor B1
ERBB2 erb-b2 receptor tyrosine kinase 2
EWSR1 EWS RNA-binding protein 1
FGFR2 fibroblast growth factor receptor 2
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOXP3 forkhead box P3
FYN FYN proto-oncogene, Src family tyrosine kinase
GLI1 GLI family zinc finger 1
HES1 hes family bHLH transcription factor 1
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
INSM1 insulinoma-associated 1
ISL1 ISL LIM homeobox 1
KEAP1 kelch-like ECH-associated protein 1
KIF5B kinesin family member 5B
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
KL klotho
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT16 keratin 16, type I
KRT19 keratin 19, type I
KRT40 keratin 40, type I
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LOC102724428 serine/threonine-protein kinase SIK1
MCAM melanoma cell adhesion molecule
MEN1 multiple endocrine neoplasia I
MGMT O-6-methylguanine-DNA methyltransferase
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NAPSA napsin A aspartic peptidase
NCAM1 neural cell adhesion molecule 1
NES nestin
NKX2-1 NK2 homeobox 1
NNAT neuronatin
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUTM1 NUT midline carcinoma, family member 1
PAX5 paired box 5
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PEBP1 phosphatidylethanolamine binding protein 1
PGK1 phosphoglycerate kinase 1
POMC proopiomelanocortin
RB1 retinoblastoma 1
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RPE65 retinal pigment epithelium-specific protein 65kDa
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SFTA2 surfactant associated 2
SIK1 salt-inducible kinase 1
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
STK11 serine/threonine kinase 11
STMN1 stathmin 1
SYNM synemin, intermediate filament protein
SYP synaptophysin
TP53 tumor protein p53
TP63 tumor protein p63
TTF1 transcription termination factor, RNA polymerase I
UBE2C ubiquitin-conjugating enzyme E2C
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UVRAG UV radiation resistance associated
VIL1 villin 1
YAP1 Yes-associated protein 1