Laryngomalacia Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description Laryngomalacia is a congenital abnormality of the laryngeal cartilage in which the cartilage is floppy and prolapses over the larynx during inspiration. (Human Phenotype Ontology, HP_0001601)
Similar Terms
Downloads & Tools

Genes

108 genes co-occuring with the disease Laryngomalacia in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
AHDC1 AT hook, DNA binding motif, containing 1 2.079
CHD7 chromodomain helicase DNA binding protein 7 1.901
PHOX2B paired-like homeobox 2b 1.832
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.779
ARID1B AT rich interactive domain 1B (SWI1-like) 1.778
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.778
EEF1AKMT1 EEF1A lysine methyltransferase 1 1.768
KAT6B K(lysine) acetyltransferase 6B 1.669
CENPVL1 centromere protein V like 1 1.596
SHOC2 soc-2 suppressor of clear homolog (C. elegans) 1.551
POLR1D polymerase (RNA) I polypeptide D, 16kDa 1.541
UBE3B ubiquitin protein ligase E3B 1.496
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa 1.487
COL2A1 collagen, type II, alpha 1 1.475
KAT6A K(lysine) acetyltransferase 6A 1.454
ORC4 origin recognition complex, subunit 4 1.427
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 1.419
IQSEC2 IQ motif and Sec7 domain 2 1.409
ERAS ES cell expressed Ras 1.404
ACTL6A actin-like 6A 1.393
TCOF1 Treacher Collins-Franceschetti syndrome 1 1.382
TBX1 T-box 1 1.362
POLR1B polymerase (RNA) I polypeptide B, 128kDa 1.355
SOS1 son of sevenless homolog 1 (Drosophila) 1.347
PGA4 pepsinogen 4, group I (pepsinogen A) 1.335
GLI3 GLI family zinc finger 3 1.333
POLR3B polymerase (RNA) III (DNA directed) polypeptide B 1.329
RIMBP3B RIMS binding protein 3B 1.322
ORC6 origin recognition complex, subunit 6 1.321
TGDS TDP-glucose 4,6-dehydratase 1.32
YIPF7 Yip1 domain family, member 7 1.319
PGA3 pepsinogen 3, group I (pepsinogen A) 1.312
ZC4H2 zinc finger, C4H2 domain containing 1.296
HRAS Harvey rat sarcoma viral oncogene homolog 1.291
NFIX nuclear factor I/X (CCAAT-binding transcription factor) 1.291
KANSL1 KAT8 regulatory NSL complex subunit 1 1.284
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa 1.279
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa 1.268
SERAC1 serine active site containing 1 1.267
OXLD1 oxidoreductase-like domain containing 1 1.265
NIPBL Nipped-B homolog (Drosophila) 1.26
ZDHHC20 zinc finger, DHHC-type containing 20 1.254
PKDCC protein kinase domain containing, cytoplasmic 1.241
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) 1.219
CSNK2B casein kinase 2, beta polypeptide 1.206
SZT2 seizure threshold 2 homolog (mouse) 1.206
DNAL1 dynein, axonemal, light chain 1 1.205
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 1.191
TBX4 T-box 4 1.189
BANF1 barrier to autointegration factor 1 1.174
PIGV phosphatidylinositol glycan anchor biosynthesis, class V 1.17
TMEM222 transmembrane protein 222 1.168
EPG5 ectopic P-granules autophagy protein 5 homolog (C. elegans) 1.156
PGA5 pepsinogen 5, group I (pepsinogen A) 1.153
RARS2 arginyl-tRNA synthetase 2, mitochondrial 1.143
SAP18 Sin3A-associated protein, 18kDa 1.143
GALNS galactosamine (N-acetyl)-6-sulfatase 1.139
UBE2A ubiquitin-conjugating enzyme E2A 1.137
ASXL2 additional sex combs like transcriptional regulator 2 1.136
SHROOM4 shroom family member 4 1.135
EVC2 Ellis van Creveld syndrome 2 1.131
XPO4 exportin 4 1.13
SOX9 SRY (sex determining region Y)-box 9 1.128
ZBTB21 zinc finger and BTB domain containing 21 1.128
VPS13B vacuolar protein sorting 13 homolog B (yeast) 1.126
NF1 neurofibromin 1 1.124
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 1.123
RTL1 retrotransposon-like 1 1.111
DNAI1 dynein, axonemal, intermediate chain 1 1.106
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 1.106
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial 1.104
IDS iduronate 2-sulfatase 1.102
ARID1A AT rich interactive domain 1A (SWI-like) 1.1
SCN4A sodium channel, voltage gated, type IV alpha subunit 1.097
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 1.097
TNNT1 troponin T type 1 (skeletal, slow) 1.085
RIMBP3C RIMS binding protein 3C 1.083
ZNF699 zinc finger protein 699 1.082
MRPL57 mitochondrial ribosomal protein L57 1.081
MANEA mannosidase, endo-alpha 1.079
TGIF1 TGFB-induced factor homeobox 1 1.076
HIRA histone cell cycle regulator 1.069
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 1.065
ACTA1 actin, alpha 1, skeletal muscle 1.065
CDT1 chromatin licensing and DNA replication factor 1 1.062
FBN1 fibrillin 1 1.062
SOX11 SRY (sex determining region Y)-box 11 1.06
RRAS2 related RAS viral (r-ras) oncogene homolog 2 1.053
STPG2 sperm-tail PG-rich repeat containing 2 1.051
ZNF672 zinc finger protein 672 1.051
APCDD1 adenomatosis polyposis coli down-regulated 1 1.05
SMAD9 SMAD family member 9 1.048
DNAH11 dynein, axonemal, heavy chain 11 1.047
SNIP1 Smad nuclear interacting protein 1 1.047
KIF7 kinesin family member 7 1.042
PAX3 paired box 3 1.041
TEX28 testis expressed 28 1.037
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 1.033
TOE1 target of EGR1, member 1 (nuclear) 1.033
MAP2K2 mitogen-activated protein kinase kinase 2 1.024
KBTBD13 kelch repeat and BTB (POZ) domain containing 13 1.021
ETV3L ets variant 3-like 1.01
CENPC centromere protein C 1.009
FKTN fukutin 1.008
LCOR ligand dependent nuclear receptor corepressor 1.006
MAGEL2 melanoma antigen family L2 1.006
KAT2A K(lysine) acetyltransferase 2A 1.003
FIG4 FIG4 phosphoinositide 5-phosphatase 1.003