Leflunomide Gene Set

Dataset HMDB Metabolites of Enzymes
Category physical interactions
Type metabolite
Description A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide. (Chemical Entities of Biological Interest Ontology, CHEBI_6402)
External Link http://www.hmdb.ca/metabolites/HMDB15229
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Genes

7 interacting proteins for the Leflunomide metabolite from the curated HMDB Metabolites of Enzymes dataset.

Symbol Name
AHR aryl hydrocarbon receptor
ALOX5 arachidonate 5-lipoxygenase
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DHODH dihydroorotate dehydrogenase (quinone)
PTK2B protein tyrosine kinase 2 beta