Left Ventricular Hypertrophy Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0149721
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Genes

377 genes associated with the disease Left Ventricular Hypertrophy in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain
ACAT1 acetyl-CoA acetyltransferase 1
ACE angiotensin I converting enzyme
ACE2 angiotensin I converting enzyme 2
ACKR3 atypical chemokine receptor 3
ACTA1 actin, alpha 1, skeletal muscle
ADAM17 ADAM metallopeptidase domain 17
ADCY6 adenylate cyclase 6
ADD1 adducin 1 (alpha)
ADIPOQ adiponectin, C1Q and collagen domain containing
ADK adenosine kinase
ADM adrenomedullin
ADRA1A adrenoceptor alpha 1A
ADRA2B adrenoceptor alpha 2B
ADRB1 adrenoceptor beta 1
ADRB2 adrenoceptor beta 2, surface
ADRB3 adrenoceptor beta 3
AGER advanced glycosylation end product-specific receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AGTR2 angiotensin II receptor, type 2
AGTRAP angiotensin II receptor-associated protein
AHR aryl hydrocarbon receptor
AHSG alpha-2-HS-glycoprotein
AIP aryl hydrocarbon receptor interacting protein
AKAP1 A kinase (PRKA) anchor protein 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALB albumin
ANGPT2 angiopoietin 2
ANXA5 annexin A5
APLN apelin
APLNR apelin receptor
APOB apolipoprotein B
APOL1 apolipoprotein L, 1
APRT adenine phosphoribosyltransferase
AR androgen receptor
ARL2BP ADP-ribosylation factor-like 2 binding protein
ATM ATM serine/threonine kinase
ATP5F1A ATP synthase F1 subunit alpha
ATP5F1D ATP synthase F1 subunit delta
ATP5PF ATP synthase peripheral stalk subunit F6
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
AVP arginine vasopressin
B3GAT3 beta-1,3-glucuronyltransferase 3
BAK1 BCL2-antagonist/killer 1
BBS1 Bardet-Biedl syndrome 1
BDKRB1 bradykinin receptor B1
BDKRB2 bradykinin receptor B2
BDNF brain-derived neurotrophic factor
BIN1 bridging integrator 1
BMP10 bone morphogenetic protein 10
BMP4 bone morphogenetic protein 4
BRS3 bombesin-like receptor 3
BSND barttin CLCNK-type chloride channel accessory beta subunit
C1QBP complement component 1, q subcomponent binding protein
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CAMTA2 calmodulin binding transcription activator 2
CAT catalase
CAV1 caveolin 1, caveolae protein, 22kDa
CCDC28B coiled-coil domain containing 28B
CCHCR1 coiled-coil alpha-helical rod protein 1
CCL2 chemokine (C-C motif) ligand 2
CCN2 cellular communication network factor 2
CD34 CD34 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD40 CD40 molecule, TNF receptor superfamily member 5
CDH15 cadherin 15, type 1, M-cadherin (myotubule)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CKB creatine kinase, brain
CKM creatine kinase, muscle
CKMT1B creatine kinase, mitochondrial 1B
CMA1 chymase 1, mast cell
CMYA5 cardiomyopathy associated 5
COL11A2 collagen, type XI, alpha 2
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
COQ9 coenzyme Q9
COX1
COX2
COX3
CPT2 carnitine palmitoyltransferase 2
CRHR2 corticotropin releasing hormone receptor 2
CROT carnitine O-octanoyltransferase
CRP C-reactive protein, pentraxin-related
CSF3 colony stimulating factor 3 (granulocyte)
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein)
CST3 cystatin C
CTF1 cardiotrophin 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL12 chemokine (C-X-C motif) ligand 12
CXCR4 chemokine (C-X-C motif) receptor 4
CXCR6 chemokine (C-X-C motif) receptor 6
CYBA cytochrome b-245, alpha polypeptide
CYBB cytochrome b-245, beta polypeptide
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
DBP D site of albumin promoter (albumin D-box) binding protein
DDAH1 dimethylarginine dimethylaminohydrolase 1
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DHDH dihydrodiol dehydrogenase (dimeric)
DMD dystrophin
DMP1 dentin matrix acidic phosphoprotein 1
DNM2 dynamin 2
DPP4 dipeptidyl-peptidase 4
DPYD dihydropyrimidine dehydrogenase
DTNA dystrobrevin, alpha
DUSP1 dual specificity phosphatase 1
ECE1 endothelin converting enzyme 1
EDN1 endothelin 1
EDNRA endothelin receptor type A
EGFR epidermal growth factor receptor
ENO1 enolase 1, (alpha)
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
EPG5 ectopic P-granules autophagy protein 5 homolog (C. elegans)
EPO erythropoietin
ERAP1 endoplasmic reticulum aminopeptidase 1
ESR1 estrogen receptor 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F9 coagulation factor IX
FABP4 fatty acid binding protein 4, adipocyte
FBN2 fibrillin 2
FGF23 fibroblast growth factor 23
FGFR1 fibroblast growth factor receptor 1
FGFR4 fibroblast growth factor receptor 4
FHL1 four and a half LIM domains 1
FKRP fukutin related protein
FN1 fibronectin 1
FNIP1 folliculin interacting protein 1
FOXO3 forkhead box O3
FSD1 fibronectin type III and SPRY domain containing 1
FSD1L fibronectin type III and SPRY domain containing 1-like
FXN frataxin
FZD2 frizzled class receptor 2
GAA glucosidase, alpha; acid
GAB1 GRB2-associated binding protein 1
GAL galanin/GMAP prepropeptide
GDF15 growth differentiation factor 15
GH1 growth hormone 1
GHSR growth hormone secretagogue receptor
GJA1 gap junction protein, alpha 1, 43kDa
GJA5 gap junction protein, alpha 5, 40kDa
GLA galactosidase, alpha
GLRX5 glutaredoxin 5
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GPR37L1 G protein-coupled receptor 37 like 1
GPR42 G protein-coupled receptor 42 (gene/pseudogene)
GRK2 G protein-coupled receptor kinase 2
GYS1 glycogen synthase 1 (muscle)
H2AX H2A.X variant histone
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HBEGF heparin-binding EGF-like growth factor
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HEXIM1 hexamethylene bis-acetamide inducible 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-C major histocompatibility complex, class I, C
HRAS Harvey rat sarcoma viral oncogene homolog
HRH1 histamine receptor H1
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HSPB8 heat shock 22kDa protein 8
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IL10 interleukin 10
IL18 interleukin 18
IL18RAP interleukin 18 receptor accessory protein
IL2 interleukin 2
IL4 interleukin 4
IL6 interleukin 6
IL6ST interleukin 6 signal transducer
IMMT inner membrane protein, mitochondrial
ITGA11 integrin, alpha 11
JPH2 junctophilin 2
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNK2 potassium channel, two pore domain subfamily K, member 2
KDM3A lysine (K)-specific demethylase 3A
KITLG KIT ligand
KL klotho
KLF15 Kruppel-like factor 15
KNG1 kininogen 1
LAMP2 lysosomal-associated membrane protein 2
LCN2 lipocalin 2
LDLR low density lipoprotein receptor
LEP leptin
LEPR leptin receptor
LGALS3 lectin, galactoside-binding, soluble, 3
LIFR leukemia inhibitory factor receptor alpha
LMNA lamin A/C
LPAR2 lysophosphatidic acid receptor 2
LPL lipoprotein lipase
LRPPRC leucine-rich pentatricopeptide repeat containing
MAP2K1 mitogen-activated protein kinase kinase 1
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAT2B methionine adenosyltransferase II, beta
MET MET proto-oncogene, receptor tyrosine kinase
MFAP1 microfibrillar-associated protein 1
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MOK MOK protein kinase
MT-CYB cytochrome b
MT-ND5 NADH dehydrogenase, subunit 5 (complex I)
MT-ND6 NADH dehydrogenase, subunit 6 (complex I)
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTPN myotrophin
MYBPC2 myosin binding protein C, fast type
MYBPC3 myosin binding protein C, cardiac
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYH6 myosin, heavy chain 6, cardiac muscle, alpha
MYH7 myosin, heavy chain 7, cardiac muscle, beta
MYL2 myosin, light chain 2, regulatory, cardiac, slow
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow
MYL9 myosin, light chain 9, regulatory
MYOZ2 myozenin 2
NCAM1 neural cell adhesion molecule 1
ND1
NEBL nebulette
NEXN nexilin (F actin binding protein)
NF1 neurofibromin 1
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NONO non-POU domain containing, octamer-binding
NOS3 nitric oxide synthase 3 (endothelial cell)
NOX4 NADPH oxidase 4
NPPA natriuretic peptide A
NPPB natriuretic peptide B
NPR1 natriuretic peptide receptor 1
NPY neuropeptide Y
NPY2R neuropeptide Y receptor Y2
NQO1 NAD(P)H dehydrogenase, quinone 1
NR3C2 nuclear receptor subfamily 3, group C, member 2
NRG1 neuregulin 1
NSF N-ethylmaleimide-sensitive factor
NUCLEOLIN nucleolin multifunctional protein
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OR10A4 olfactory receptor, family 10, subfamily A, member 4
ORM1 orosomucoid 1
PARP1 poly (ADP-ribose) polymerase 1
PBRM1 polybromo 1
PDE1A phosphodiesterase 1A, calmodulin-dependent
PDE2A phosphodiesterase 2A, cGMP-stimulated
PDE3A phosphodiesterase 3A, cGMP-inhibited
PDE5A phosphodiesterase 5A, cGMP-specific
PECAM1 platelet/endothelial cell adhesion molecule 1
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLN phospholamban
POLG polymerase (DNA directed), gamma
POLG2 polymerase (DNA directed), gamma 2, accessory subunit
POMT1 protein-O-mannosyltransferase 1
PON1 paraoxonase 1
PON2 paraoxonase 2
POSTN periostin, osteoblast specific factor
PPARA peroxisome proliferator-activated receptor alpha
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKCZ protein kinase C, zeta
PRL prolactin
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH parathyroid hormone
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTN pleiotrophin
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REN renin
RHOA ras homolog family member A
RIT1 Ras-like without CAAX 1
RNLS renalase, FAD-dependent amine oxidase
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
RYR1 ryanodine receptor 1 (skeletal)
S100A1 S100 calcium binding protein A1
S100B S100 calcium binding protein B
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SDHAF1 succinate dehydrogenase complex assembly factor 1
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SELENBP1 selenium binding protein 1
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SHBG sex hormone-binding globulin
SIRT1 sirtuin 1
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SLC25A46 solute carrier family 25, member 46
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMAD3 SMAD family member 3
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMC3 structural maintenance of chromosomes 3
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SOX9 SRY (sex determining region Y)-box 9
SPEG SPEG complex locus
SPP1 secreted phosphoprotein 1
SSTR4 somatostatin receptor 4
STK11 serine/threonine kinase 11
SYNM synemin, intermediate filament protein
TAS2R13 taste receptor, type 2, member 13
TGFB1 transforming growth factor, beta 1
TGM2 transglutaminase 2
THBS1 thrombospondin 1
THRA thyroid hormone receptor, alpha
THRB thyroid hormone receptor, beta
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TIMP4 TIMP metallopeptidase inhibitor 4
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNC tenascin C
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNNI3 troponin I type 3 (cardiac)
TNNT2 troponin T type 2 (cardiac)
TPM1 tropomyosin 1 (alpha)
TRIB3 tribbles pseudokinase 3
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TTN titin
TTR transthyretin
TWNK twinkle mtDNA helicase
TXNRD3 thioredoxin reductase 3
UCN urocortin
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
VCAM1 vascular cell adhesion molecule 1
VCP valosin containing protein
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae)
VPS51 vacuolar protein sorting 51 homolog (S. cerevisiae)
WDHD1 WD repeat and HMG-box DNA binding protein 1
WDR35 WD repeat domain 35
XDH xanthine dehydrogenase
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZMPSTE24 zinc metallopeptidase STE24