Leg Ulcer Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0023223
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Genes

38 genes associated with the disease Leg Ulcer in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5
BCL2 B-cell CLL/lymphoma 2
CAMP cathelicidin antimicrobial peptide
CCL3 chemokine (C-C motif) ligand 3
CCL4 chemokine (C-C motif) ligand 4
CCL4L1 chemokine (C-C motif) ligand 4-like 1
CCL4L2 chemokine (C-C motif) ligand 4-like 2
CLDN1 claudin 1
CLDN3 claudin 3
CLDN5 claudin 5
COL11A2 collagen, type XI, alpha 2
COMP cartilage oligomeric matrix protein
DEFA1 defensin, alpha 1
DEFA3 defensin, alpha 3, neutrophil-specific
F13A1 coagulation factor XIII, A1 polypeptide
F2 coagulation factor II (thrombin)
GJA1 gap junction protein, alpha 1, 43kDa
HBA1 hemoglobin, alpha 1
HBA2 hemoglobin, alpha 2
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
ICAM1 intercellular adhesion molecule 1
IL1B interleukin 1, beta
IL6 interleukin 6
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KL klotho
MMP2 matrix metallopeptidase 2
NRP1 neuropilin 1
OCLN occludin
PARP1 poly (ADP-ribose) polymerase 1
PLAU plasminogen activator, urokinase
PLG plasminogen
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SDC4 syndecan 4
SELE selectin E
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
TNF tumor necrosis factor
VEGFA vascular endothelial growth factor A