Legg-Calve-Perthes Disease Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description An osteochondrosis that results_in death and fracture located_in hip joint. (Human Disease Ontology, DOID_14415)
External Link https://www.disgenet.org/browser/0/1/0/C0023234
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Genes

34 genes associated with the disease Legg-Calve-Perthes Disease in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2
ATP7A ATPase, Cu++ transporting, alpha polypeptide
BAX BCL2-associated X protein
BGLAP bone gamma-carboxyglutamate (gla) protein
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
COL2A1 collagen, type II, alpha 1
COMP cartilage oligomeric matrix protein
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous)
CREBBP CREB binding protein
DVL1 dishevelled segment polarity protein 1
DVL3 dishevelled segment polarity protein 3
EP300 E1A binding protein p300
EXT1 exostosin glycosyltransferase 1
F5 coagulation factor V (proaccelerin, labile factor)
FGB fibrinogen beta chain
FZD2 frizzled class receptor 2
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
IL6 interleukin 6
INPP5K inositol polyphosphate-5-phosphatase K
LPA lipoprotein, Lp(a)
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NAGLU N-acetylglucosaminidase, alpha
NR4A3 nuclear receptor subfamily 4, group A, member 3
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SIL1 SIL1 nucleotide exchange factor
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SOX9 SRY (sex determining region Y)-box 9
SRCAP Snf2-related CREBBP activator protein
TNF tumor necrosis factor
TRPS1 trichorhinophalangeal syndrome I
TRPV4 transient receptor potential cation channel, subfamily V, member 4
UFSP2 UFM1-specific peptidase 2
WNT5A wingless-type MMTV integration site family, member 5A