Leiomyoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A cell type benign neoplasm that is a benign tumor of smooth muscle cells. (Human Disease Ontology, DOID_127)
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Genes

591 genes co-occuring with the disease Leiomyoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
FH fumarate hydratase 3.591
CALD1 caldesmon 1 3.324
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 3.234
MED12 mediator complex subunit 12 3.207
CD34 CD34 molecule 3.181
ANO1 anoctamin 1, calcium activated chloride channel 3.114
PGR progesterone receptor 2.956
COL4A6 collagen, type IV, alpha 6 2.86
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 2.799
ESR1 estrogen receptor 1 2.78
HMGA2 high mobility group AT-hook 2 2.71
COL4A5 collagen, type IV, alpha 5 2.707
MME membrane metallo-endopeptidase 2.615
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 2.549
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 2.485
TP53 tumor protein p53 2.456
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 2.421
FLCN folliculin 2.413
CD99L2 CD99 molecule-like 2 2.377
CD99 CD99 molecule 2.352
TFE3 transcription factor binding to IGHM enhancer 3 2.337
TGFB3 transforming growth factor, beta 3 2.332
TSC2 tuberous sclerosis 2 2.32
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 2.307
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 2.297
CALB2 calbindin 2 2.281
BCL2 B-cell CLL/lymphoma 2 2.25
KRT7 keratin 7, type II 2.231
CDKN2A cyclin-dependent kinase inhibitor 2A 2.217
PECAM1 platelet/endothelial cell adhesion molecule 1 2.182
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 2.179
ALK anaplastic lymphoma receptor tyrosine kinase 2.17
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 2.168
MTOR mechanistic target of rapamycin (serine/threonine kinase) 2.154
PCNA proliferating cell nuclear antigen 2.138
PTEN phosphatase and tensin homolog 2.132
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 2.126
ENO2 enolase 2 (gamma, neuronal) 2.108
WT1 Wilms tumor 1 2.103
MYOG myogenin (myogenic factor 4) 2.089
SYP synaptophysin 2.087
JAZF1 JAZF zinc finger 1 2.078
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 2.07
MEN1 multiple endocrine neoplasia I 2.053
TGFB1 transforming growth factor, beta 1 2.042
FN1 fibronectin 1 2.037
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 2.037
NF1 neurofibromin 1 2.037
EPAS1 endothelial PAS domain protein 1 2.031
HOXA10 homeobox A10 2.029
VCAN versican 2.027
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 2.017
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.006
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.994
SDHAF2 succinate dehydrogenase complex assembly factor 2 1.992
CCND1 cyclin D1 1.987
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 1.987
WNT4 wingless-type MMTV integration site family, member 4 1.984
ESR2 estrogen receptor 2 (ER beta) 1.983
PAX8 paired box 8 1.982
MITF microphthalmia-associated transcription factor 1.975
CD68 CD68 molecule 1.971
IGF2 insulin-like growth factor 2 1.958
AMH anti-Mullerian hormone 1.943
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.942
SOX10 SRY (sex determining region Y)-box 10 1.941
SETD2 SET domain containing 2 1.936
ELOC elongin C 1.928
IGF1 insulin-like growth factor 1 (somatomedin C) 1.926
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 1.907
NCAM1 neural cell adhesion molecule 1 1.907
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.905
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1.9
EGF epidermal growth factor 1.896
PBRM1 polybromo 1 1.887
KEAP1 kelch-like ECH-associated protein 1 1.885
BET1L Bet1 golgi vesicular membrane trafficking protein-like 1.879
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.877
KLF11 Kruppel-like factor 11 1.873
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 1.865
LDHA lactate dehydrogenase A 1.861
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 1.86
COL4A4 collagen, type IV, alpha 4 1.84
AFP alpha-fetoprotein 1.836
NF2 neurofibromin 2 (merlin) 1.834
MYOD1 myogenic differentiation 1 1.832
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 1.831
TFEB transcription factor EB 1.828
PLAG1 pleiomorphic adenoma gene 1 1.827
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.823
DPT dermatopontin 1.813
RAD51B RAD51 paralog B 1.808
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 1.799
PRL prolactin 1.795
KANSL1 KAT8 regulatory NSL complex subunit 1 1.789
EGFR epidermal growth factor receptor 1.786
ZC3H7B zinc finger CCCH-type containing 7B 1.779
KAT6B K(lysine) acetyltransferase 6B 1.771
NUTM2A NUT family member 2A 1.771
COL1A1 collagen, type I, alpha 1 1.77
KRT20 keratin 20, type I 1.769
PXDNL peroxidasin-like 1.748
AMACR alpha-methylacyl-CoA racemase 1.748
PXDN peroxidasin 1.746
SUZ12 SUZ12 polycomb repressive complex 2 subunit 1.744
OXT oxytocin/neurophysin I prepropeptide 1.742
CCNC cyclin C 1.742
CHGA chromogranin A 1.739
MET MET proto-oncogene, receptor tyrosine kinase 1.737
CDK8 cyclin-dependent kinase 8 1.733
ATRX alpha thalassemia/mental retardation syndrome X-linked 1.73
CA9 carbonic anhydrase IX 1.72
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.717
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 1.716
IGF1R insulin-like growth factor 1 receptor 1.714
EGLN1 egl-9 family hypoxia-inducible factor 1 1.713
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 1.71
COMT catechol-O-methyltransferase 1.707
KRAS Kirsten rat sarcoma viral oncogene homolog 1.698
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) 1.698
BRCA1 breast cancer 1, early onset 1.696
ACTB actin, beta 1.681
TSC1 tuberous sclerosis 1 1.679
BRAF B-Raf proto-oncogene, serine/threonine kinase 1.677
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.674
FGF2 fibroblast growth factor 2 (basic) 1.672
ACO2 aconitase 2, mitochondrial 1.668
FMOD fibromodulin 1.665
CDK4 cyclin-dependent kinase 4 1.659
CDC73 cell division cycle 73 1.658
MYH14 myosin, heavy chain 14, non-muscle 1.655
GNRHR gonadotropin-releasing hormone receptor 1.648
OXTR oxytocin receptor 1.644
PDGFRB platelet-derived growth factor receptor, beta polypeptide 1.64
PHF1 PHD finger protein 1 1.639
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 1.63
CCN5 cellular communication network factor 5 1.626
RET ret proto-oncogene 1.622
TGFA transforming growth factor, alpha 1.62
MMP2 matrix metallopeptidase 2 1.617
NFE2L2 nuclear factor, erythroid 2-like 2 1.616
HOXA11 homeobox A11 1.615
MMP9 matrix metallopeptidase 9 1.613
TMEM127 transmembrane protein 127 1.613
MEAF6 MYST/Esa1-associated factor 6 1.613
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.611
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.61
GREB1 growth regulation by estrogen in breast cancer 1 1.601
CTSK cathepsin K 1.6
EWSR1 EWS RNA-binding protein 1 1.598
KRT5 keratin 5, type II 1.588
AR androgen receptor 1.581
ARMC5 armadillo repeat containing 5 1.576
ARID1A AT rich interactive domain 1A (SWI-like) 1.575
PDPN podoplanin 1.573
SMTN smoothelin 1.566
ARNT aryl hydrocarbon receptor nuclear translocator 1.564
HOOK2 hook microtubule-tethering protein 2 1.559
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 1.557
TERT telomerase reverse transcriptase 1.556
PCP4 Purkinje cell protein 4 1.551
MB myoglobin 1.547
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.542
H3-3B H3.3 histone B 1.538
ERBB2 erb-b2 receptor tyrosine kinase 2 1.537
JUN jun proto-oncogene 1.536
INS insulin 1.534
CDK2 cyclin-dependent kinase 2 1.532
COL3A1 collagen, type III, alpha 1 1.531
CRP C-reactive protein, pentraxin-related 1.53
TNRC6B trinucleotide repeat containing 6B 1.53
CCN2 cellular communication network factor 2 1.529
S100A6 S100 calcium binding protein A6 1.52
DLEC1 deleted in lung and esophageal cancer 1 1.517
MUC1 mucin 1, cell surface associated 1.516
CR2 complement component (3d/Epstein Barr virus) receptor 2 1.514
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.51
PRLHR prolactin releasing hormone receptor 1.508
CUL3 cullin 3 1.507
LRTOMT leucine rich transmembrane and O-methyltransferase domain containing 1.506
BRCA2 breast cancer 2, early onset 1.506
FBXW2 F-box and WD repeat domain containing 2 1.506
H3-4 H3.4 histone, cluster member 1.497
EGLN2 egl-9 family hypoxia-inducible factor 2 1.494
TNF tumor necrosis factor 1.491
MED13 mediator complex subunit 13 1.49
MAPK3 mitogen-activated protein kinase 3 1.489
PKM pyruvate kinase, muscle 1.484
MLH1 mutL homolog 1 1.483
EIF5B eukaryotic translation initiation factor 5B 1.482
H3-5 H3.5 histone 1.482
H3C13 H3 clustered histone 13 1.482
SHBG sex hormone-binding globulin 1.482
ALB albumin 1.481
IL6 interleukin 6 1.48
H3C12 H3 clustered histone 12 1.478
KDR kinase insert domain receptor 1.477
CCDC57 coiled-coil domain containing 57 1.475
L2HGDH L-2-hydroxyglutarate dehydrogenase 1.475
FOS FBJ murine osteosarcoma viral oncogene homolog 1.474
STK11 serine/threonine kinase 11 1.467
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 1.461
FNIP1 folliculin interacting protein 1 1.459
RB1 retinoblastoma 1 1.459
GPER1 G protein-coupled estrogen receptor 1 1.459
CD274 CD274 molecule 1.457
FOXO1 forkhead box O1 1.456
ACLY ATP citrate lyase 1.453
PDE11A phosphodiesterase 11A 1.451
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 1.451
IRS4 insulin receptor substrate 4 1.449
PTPRC protein tyrosine phosphatase, receptor type, C 1.448
SMAD3 SMAD family member 3 1.447
FLT1 fms-related tyrosine kinase 1 1.446
MSH6 mutS homolog 6 1.445
FGF17 fibroblast growth factor 17 1.439
ZEB1 zinc finger E-box binding homeobox 1 1.438
ATM ATM serine/threonine kinase 1.437
FGF4 fibroblast growth factor 4 1.435
AKAP13 A kinase (PRKA) anchor protein 13 1.435
DCN decorin 1.433
MSH2 mutS homolog 2 1.431
KRT8 keratin 8, type II 1.43
HMGA1 high mobility group AT-hook 1 1.43
CD44 CD44 molecule (Indian blood group) 1.427
KITLG KIT ligand 1.426
HRAS Harvey rat sarcoma viral oncogene homolog 1.426
KRT19 keratin 19, type I 1.425
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 1.42
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.42
FGF7 fibroblast growth factor 7 1.416
CCND2 cyclin D2 1.415
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 1.414
FGF3 fibroblast growth factor 3 1.414
FGF6 fibroblast growth factor 6 1.411
FGF10 fibroblast growth factor 10 1.41
FGF22 fibroblast growth factor 22 1.408
EGLN3 egl-9 family hypoxia-inducible factor 3 1.406
FGF16 fibroblast growth factor 16 1.406
SMAD2 SMAD family member 2 1.406
BAX BCL2-associated X protein 1.404
ASL argininosuccinate lyase 1.403
FGF20 fibroblast growth factor 20 1.403
KDM5C lysine (K)-specific demethylase 5C 1.402
PARP1 poly (ADP-ribose) polymerase 1 1.398
FGF18 fibroblast growth factor 18 1.398
CYTH4 cytohesin 4 1.398
FGF5 fibroblast growth factor 5 1.398
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 1.397
FNIP2 folliculin interacting protein 2 1.396
FGF8 fibroblast growth factor 8 (androgen-induced) 1.394
GJA1 gap junction protein, alpha 1, 43kDa 1.394
PDE8B phosphodiesterase 8B 1.394
CCN4 cellular communication network factor 4 1.392
AMHR2 anti-Mullerian hormone receptor, type II 1.39
FGF9 fibroblast growth factor 9 1.388
CD8A CD8a molecule 1.388
VIM vimentin 1.385
KDM6A lysine (K)-specific demethylase 6A 1.382
NCOA2 nuclear receptor coactivator 2 1.379
ACO1 aconitase 1, soluble 1.377
ADM adrenomedullin 1.375
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 1.37
CXCL8 chemokine (C-X-C motif) ligand 8 1.364
VIPR2 vasoactive intestinal peptide receptor 2 1.362
IGFBP1 insulin-like growth factor binding protein 1 1.361
MMP11 matrix metallopeptidase 11 1.361
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 1.359
SMAD4 SMAD family member 4 1.351
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 1.347
FOXL2 forkhead box L2 1.347
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) 1.345
TAGLN3 transgelin 3 1.344
PAEP progestagen-associated endometrial protein 1.343
TAGLN transgelin 1.342
EPO erythropoietin 1.34
NCOA1 nuclear receptor coactivator 1 1.339
RHEB Ras homolog enriched in brain 1.338
CDK19 cyclin-dependent kinase 19 1.335
KDM4B lysine (K)-specific demethylase 4B 1.333
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3 1.332
PRKCQ protein kinase C, theta 1.332
G6PD glucose-6-phosphate dehydrogenase 1.328
PAX2 paired box 2 1.327
SST somatostatin 1.327
TET1 tet methylcytosine dioxygenase 1 1.327
DICER1 dicer 1, ribonuclease type III 1.325
FGFR1 fibroblast growth factor receptor 1 1.325
POU5F1 POU class 5 homeobox 1 1.324
PBX3 pre-B-cell leukemia homeobox 3 1.321
KDM4A lysine (K)-specific demethylase 4A 1.318
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.317
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.317
MMP1 matrix metallopeptidase 1 1.31
GFAP glial fibrillary acidic protein 1.31
CCN3 cellular communication network factor 3 1.309
IL1B interleukin 1, beta 1.306
ZBTB48 zinc finger and BTB domain containing 48 1.305
IFITM1 interferon induced transmembrane protein 1 1.303
TGFB2 transforming growth factor, beta 2 1.3
ACTG2 actin, gamma 2, smooth muscle, enteric 1.299
CD4 CD4 molecule 1.294
MYOF myoferlin 1.292
NUTM2B NUT family member 2B 1.29
CARMIL2 capping protein regulator and myosin 1 linker 2 1.289
KDM2B lysine (K)-specific demethylase 2B 1.285
PDGFB platelet-derived growth factor beta polypeptide 1.285
CHEK2 checkpoint kinase 2 1.285
GLS glutaminase 1.283
TIMP2 TIMP metallopeptidase inhibitor 2 1.282
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 1.279
PDK1 pyruvate dehydrogenase kinase, isozyme 1 1.277
CRABP2 cellular retinoic acid binding protein 2 1.277
DNER delta/notch-like EGF repeat containing 1.277
GATA3 GATA binding protein 3 1.276
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.276
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.275
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 1.275
NR5A1 nuclear receptor subfamily 5, group A, member 1 1.274
CDX2 caudal type homeobox 2 1.272
MSTN myostatin 1.272
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 1.271
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 1.27
POMC proopiomelanocortin 1.269
LDHD lactate dehydrogenase D 1.267
KLK3 kallikrein-related peptidase 3 1.266
CUL2 cullin 2 1.265
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.264
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 1.263
THBS1 thrombospondin 1 1.261
C19ORF38 chromosome 19 open reading frame 38 1.261
ZNHIT1 zinc finger, HIT-type containing 1 1.259
TET2 tet methylcytosine dioxygenase 2 1.258
GAST gastrin 1.256
GLMN glomulin, FKBP associated protein 1.255
CDH16 cadherin 16, KSP-cadherin 1.254
EDN1 endothelin 1 1.253
SLC16A4 solute carrier family 16, member 4 1.253
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 1.252
NKX2-1 NK2 homeobox 1 1.25
DAXX death-domain associated protein 1.249
ELOB elongin B 1.248
TDO2 tryptophan 2,3-dioxygenase 1.246
PGD phosphogluconate dehydrogenase 1.245
LIF leukemia inhibitory factor 1.244
BMPR1A bone morphogenetic protein receptor, type IA 1.238
FBLN5 fibulin 5 1.236
CUX1 cut-like homeobox 1 1.236
TET3 tet methylcytosine dioxygenase 3 1.236
CCN6 cellular communication network factor 6 1.234
COL4A2 collagen, type IV, alpha 2 1.233
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 1.232
VWF von Willebrand factor 1.232
CCN1 cellular communication network factor 1 1.231
GLS2 glutaminase 2 (liver, mitochondrial) 1.228
PLD5 phospholipase D family, member 5 1.227
TAGLN2 transgelin 2 1.225
IRS1 insulin receptor substrate 1 1.224
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 1.224
SSX2 synovial sarcoma, X breakpoint 2 1.223
RHOA ras homolog family member A 1.222
CS citrate synthase 1.222
TCHP trichoplein, keratin filament binding 1.222
CCL2 chemokine (C-C motif) ligand 2 1.22
BCORL1 BCL6 corepressor-like 1 1.219
KLF9 Kruppel-like factor 9 1.217
COL4A1 collagen, type IV, alpha 1 1.216
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.216
RBP1 retinol binding protein 1, cellular 1.215
SNAI1 snail family zinc finger 1 1.214
IFNG interferon, gamma 1.212
VIP vasoactive intestinal peptide 1.211
MAPK1 mitogen-activated protein kinase 1 1.211
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 1.209
ASS1 argininosuccinate synthase 1 1.207
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 1.204
MKI67 marker of proliferation Ki-67 1.204
ZEB2 zinc finger E-box binding homeobox 2 1.202
TIMP1 TIMP metallopeptidase inhibitor 1 1.201
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 1.2
CD79A CD79a molecule, immunoglobulin-associated alpha 1.192
DNTT DNA nucleotidylexotransferase 1.192
WNT16 wingless-type MMTV integration site family, member 16 1.191
NANOG Nanog homeobox 1.191
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 1.191
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.189
PPARG peroxisome proliferator-activated receptor gamma 1.188
D2HGDH D-2-hydroxyglutarate dehydrogenase 1.185
HOXA13 homeobox A13 1.184
NCOA3 nuclear receptor coactivator 3 1.184
HOXA9 homeobox A9 1.182
ESPN espin 1.179
NR4A3 nuclear receptor subfamily 4, group A, member 3 1.178
IL2 interleukin 2 1.175
NES nestin 1.175
B3GAT1 beta-1,3-glucuronyltransferase 1 1.174
BCL6 B-cell CLL/lymphoma 6 1.174
FST follistatin 1.174
PFKM phosphofructokinase, muscle 1.172
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 1.171
MMP14 matrix metallopeptidase 14 (membrane-inserted) 1.168
PTGER4 prostaglandin E receptor 4 (subtype EP4) 1.166
HBEGF heparin-binding EGF-like growth factor 1.164
CAV1 caveolin 1, caveolae protein, 22kDa 1.161
RGS7 regulator of G-protein signaling 7 1.154
SMAD7 SMAD family member 7 1.154
GSK3B glycogen synthase kinase 3 beta 1.154
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 1.153
CYCS cytochrome c, somatic 1.152
PC pyruvate carboxylase 1.151
FUS FUS RNA binding protein 1.149
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.148
INSR insulin receptor 1.148
EGR1 early growth response 1 1.142
EP300 E1A binding protein p300 1.141
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1.14
STN1 STN1 subunit of CST complex 1.139
PTH parathyroid hormone 1.138
MYOCD myocardin 1.138
FBLIM1 filamin binding LIM protein 1 1.137
WNT7A wingless-type MMTV integration site family, member 7A 1.137
FASN fatty acid synthase 1.134
TKTL2 transketolase-like 2 1.131
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.13
GLI1 GLI family zinc finger 1 1.128
PALB2 partner and localizer of BRCA2 1.128
HDAC9 histone deacetylase 9 1.126
TKTL1 transketolase-like 1 1.126
PTCH1 patched 1 1.124
TIGAR TP53 induced glycolysis regulatory phosphatase 1.123
NQO1 NAD(P)H dehydrogenase, quinone 1 1.122
HMOX1 heme oxygenase 1 1.122
CD1E CD1e molecule 1.122
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 1.12
KMT2D lysine (K)-specific methyltransferase 2D 1.117
IL10 interleukin 10 1.117
ENG endoglin 1.117
TPM3 tropomyosin 3 1.116
MEST mesoderm specific transcript 1.113
KRT18 keratin 18, type I 1.112
PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 1.111
CD1A CD1a molecule 1.111
MED8 mediator complex subunit 8 1.11
SUSD2 sushi domain containing 2 1.109
MMP3 matrix metallopeptidase 3 1.109
MUC4 mucin 4, cell surface associated 1.108
MMP7 matrix metallopeptidase 7 1.106
PAX5 paired box 5 1.106
LHFPL3 lipoma HMGIC fusion partner-like 3 1.105
IDH3B isocitrate dehydrogenase 3 (NAD+) beta 1.105
RASA1 RAS p21 protein activator (GTPase activating protein) 1 1.104
CD1B CD1b molecule 1.104
TKT transketolase 1.102
BGN biglycan 1.101
E2F1 E2F transcription factor 1 1.101
LUM lumican 1.101
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 1.101
MED18 mediator complex subunit 18 1.101
POLE polymerase (DNA directed), epsilon, catalytic subunit 1.101
NOG noggin 1.1
ISOC1 isochorismatase domain containing 1 1.1
VSTM2A V-set and transmembrane domain containing 2A 1.1
H2AZ1 H2A.Z variant histone 1 1.1
ACSS2 acyl-CoA synthetase short-chain family member 2 1.1
LHCGR luteinizing hormone/choriogonadotropin receptor 1.098
BRD8 bromodomain containing 8 1.098
FAM9A family with sequence similarity 9, member A 1.097
VIPR1 vasoactive intestinal peptide receptor 1 1.097
SFRP1 secreted frizzled-related protein 1 1.096
SSX1 synovial sarcoma, X breakpoint 1 1.096
PTHLH parathyroid hormone-like hormone 1.096
INSM1 insulinoma-associated 1 1.095
PDGFA platelet-derived growth factor alpha polypeptide 1.094
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.093
S100A1 S100 calcium binding protein A1 1.092
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.092
SCFD2 sec1 family domain containing 2 1.09
ETV6 ets variant 6 1.09
MCM8 minichromosome maintenance complex component 8 1.089
S100G S100 calcium binding protein G 1.089
BIRC5 baculoviral IAP repeat containing 5 1.089
IFNA1 interferon, alpha 1 1.088
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 1.088
SATB2 SATB homeobox 2 1.088
PRKDC protein kinase, DNA-activated, catalytic polypeptide 1.087
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase 1.086
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.082
MYH11 myosin, heavy chain 11, smooth muscle 1.082
MAX MYC associated factor X 1.081
FSHR follicle stimulating hormone receptor 1.081
GNRH2 gonadotropin-releasing hormone 2 1.081
BCL2L1 BCL2-like 1 1.08
SS18 synovial sarcoma translocation, chromosome 18 1.08
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 1.08
KAT6A K(lysine) acetyltransferase 6A 1.079
GCG glucagon 1.078
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 1.078
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.077
SUCNR1 succinate receptor 1 1.077
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 1.077
JUND jun D proto-oncogene 1.076
F2 coagulation factor II (thrombin) 1.076
ANXA5 annexin A5 1.076
CPXCR1 CPX chromosome region, candidate 1 1.075
CDKN3 cyclin-dependent kinase inhibitor 3 1.075
CD1C CD1c molecule 1.075
POTEF POTE ankyrin domain family, member F 1.075
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 1.074
CCNL2 cyclin L2 1.073
MED12L mediator complex subunit 12-like 1.073
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 1.073
GNAS GNAS complex locus 1.072
CNN1 calponin 1, basic, smooth muscle 1.072
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 1.071
GSTM1 glutathione S-transferase mu 1 1.071
WNT5B wingless-type MMTV integration site family, member 5B 1.071
ACSS1 acyl-CoA synthetase short-chain family member 1 1.07
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 1.067
FGF1 fibroblast growth factor 1 (acidic) 1.066
FLT4 fms-related tyrosine kinase 4 1.065
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.063
SCO2 SCO2 cytochrome c oxidase assembly protein 1.062
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 1.058
GPX4 glutathione peroxidase 4 1.058
SNAI2 snail family zinc finger 2 1.058
IGFBP5 insulin-like growth factor binding protein 5 1.056
ACVR1B activin A receptor, type IB 1.056
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.052
PAX3 paired box 3 1.052
SIRT3 sirtuin 3 1.05
CREB1 cAMP responsive element binding protein 1 1.049
ADSL adenylosuccinate lyase 1.049
FAM241B family with sequence similarity 241 member B 1.048
BMP2 bone morphogenetic protein 2 1.048
IL11 interleukin 11 1.047
YEATS4 YEATS domain containing 4 1.046
IL1A interleukin 1, alpha 1.046
PHGDH phosphoglycerate dehydrogenase 1.046
HK2 hexokinase 2 1.045
ZNF444 zinc finger protein 444 1.043
KLF4 Kruppel-like factor 4 (gut) 1.043
NAPSA napsin A aspartic peptidase 1.043
CD1D CD1d molecule 1.041
EPCAM epithelial cell adhesion molecule 1.041
HIF3A hypoxia inducible factor 3, alpha subunit 1.04
ALPP alkaline phosphatase, placental 1.039
SOX2 SRY (sex determining region Y)-box 2 1.039
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 1.038
ENO1 enolase 1, (alpha) 1.036
HNF4A hepatocyte nuclear factor 4, alpha 1.035
HAND2 heart and neural crest derivatives expressed 2 1.035
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 1.034
TYR tyrosinase 1.033
SPP1 secreted phosphoprotein 1 1.032
AGAP6 ArfGAP with GTPase domain, ankyrin repeat and PH domain 6 1.032
KRTAP1-5 keratin associated protein 1-5 1.031
PGK1 phosphoglycerate kinase 1 1.031
TG thyroglobulin 1.03
IFNA17 interferon, alpha 17 1.03
SDC1 syndecan 1 1.029
IREB2 iron-responsive element binding protein 2 1.029
RBX1 ring-box 1, E3 ubiquitin protein ligase 1.029
PDCD1 programmed cell death 1 1.028
GATA2 GATA binding protein 2 1.027
FSCN1 fascin actin-bundling protein 1 1.026
SDHAF1 succinate dehydrogenase complex assembly factor 1 1.024
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.024
FSHB follicle stimulating hormone, beta polypeptide 1.024
CLDN1 claudin 1 1.022
CA2 carbonic anhydrase II 1.021
PRUNE2 prune homolog 2 (Drosophila) 1.02
ELN elastin 1.019
BMP15 bone morphogenetic protein 15 1.017
VEGFD vascular endothelial growth factor D 1.015
TXN thioredoxin 1.014
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 1.014
GPR20 G protein-coupled receptor 20 1.012
YAP1 Yes-associated protein 1 1.012
TIMP3 TIMP metallopeptidase inhibitor 3 1.011
CLTC clathrin, heavy chain (Hc) 1.011
PRODH proline dehydrogenase (oxidase) 1 1.01
LTBP1 latent transforming growth factor beta binding protein 1 1.01
PTGER3 prostaglandin E receptor 3 (subtype EP3) 1.01
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.007
KAT2B K(lysine) acetyltransferase 2B 1.007
PBX1 pre-B-cell leukemia homeobox 1 1.006
F3 coagulation factor III (thromboplastin, tissue factor) 1.005
CPXM1 carboxypeptidase X (M14 family), member 1 1.005
NR2F2 nuclear receptor subfamily 2, group F, member 2 1.004
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.0
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 1.0