Leiomyosarcoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A sarcoma containing large spindle cells of smooth muscle. Although it rarely occurs in soft tissue, it is common in the viscera. It is the most common soft tissue sarcoma of the gastrointestinal tract and uterus. The median age of patients is 60 years. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p1865)|A malignant smooth muscle cancer that can arise almost anywhere in the body, but is most common in the uterus, abdomen, or pelvis.|An uncommon, aggressive malignant smooth muscle neoplasm, usually occurring in post-menopausal women. It is characterized by a proliferation of neoplastic spindle cells. Morphologic variants include epithelioid, granular cell, inflammatory and myxoid leimyosarcomas. (Experimental Factor Ontology, EFO_0000564)
Similar Terms
Downloads & Tools

Genes

609 genes co-occuring with the disease Leiomyosarcoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
CALD1 caldesmon 1 3.516
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 3.266
CD34 CD34 molecule 3.174
ANO1 anoctamin 1, calcium activated chloride channel 3.036
MYOG myogenin (myogenic factor 4) 2.889
TP53 tumor protein p53 2.825
SSX2 synovial sarcoma, X breakpoint 2 2.747
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 2.744
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 2.736
CD99 CD99 molecule 2.713
MED12 mediator complex subunit 12 2.686
CD99L2 CD99 molecule-like 2 2.685
EWSR1 EWS RNA-binding protein 1 2.585
SSX1 synovial sarcoma, X breakpoint 1 2.569
MYOD1 myogenic differentiation 1 2.558
MME membrane metallo-endopeptidase 2.543
CDK4 cyclin-dependent kinase 4 2.518
CDKN2A cyclin-dependent kinase inhibitor 2A 2.484
PGR progesterone receptor 2.473
ALK anaplastic lymphoma receptor tyrosine kinase 2.468
ATRX alpha thalassemia/mental retardation syndrome X-linked 2.454
PECAM1 platelet/endothelial cell adhesion molecule 1 2.417
ZC3H7B zinc finger CCCH-type containing 7B 2.414
CD68 CD68 molecule 2.413
PTEN phosphatase and tensin homolog 2.399
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 2.394
JAZF1 JAZF zinc finger 1 2.364
ESR1 estrogen receptor 1 2.359
SS18 synovial sarcoma translocation, chromosome 18 2.354
SOX10 SRY (sex determining region Y)-box 10 2.338
NF1 neurofibromin 1 2.336
CD274 CD274 molecule 2.326
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 2.31
BCL2 B-cell CLL/lymphoma 2 2.288
HMGA2 high mobility group AT-hook 2 2.276
MTOR mechanistic target of rapamycin (serine/threonine kinase) 2.267
WT1 Wilms tumor 1 2.247
PDGFRB platelet-derived growth factor receptor, beta polypeptide 2.245
KRT7 keratin 7, type II 2.244
FH fumarate hydratase 2.244
NUTM2A NUT family member 2A 2.237
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 2.236
CALB2 calbindin 2 2.218
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 2.216
PAX3 paired box 3 2.186
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.182
SSX4B synovial sarcoma, X breakpoint 4B 2.179
ENO2 enolase 2 (gamma, neuronal) 2.176
SSX4 synovial sarcoma, X breakpoint 4 2.173
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 2.17
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 2.156
MB myoglobin 2.154
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 2.151
FUS FUS RNA binding protein 2.139
ERBB2 erb-b2 receptor tyrosine kinase 2 2.127
SYP synaptophysin 2.103
EGFR epidermal growth factor receptor 2.096
SSX2B synovial sarcoma, X breakpoint 2B 2.094
CCND1 cyclin D1 2.079
TFE3 transcription factor binding to IGHM enhancer 3 2.077
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 2.076
PRUNE2 prune homolog 2 (Drosophila) 2.074
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 2.074
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 2.068
MYC v-myc avian myelocytomatosis viral oncogene homolog 2.068
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 2.064
BRCA1 breast cancer 1, early onset 2.064
SUZ12 SUZ12 polycomb repressive complex 2 subunit 2.062
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 2.053
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 2.04
IGF2 insulin-like growth factor 2 2.038
MYH14 myosin, heavy chain 14, non-muscle 2.038
KRAS Kirsten rat sarcoma viral oncogene homolog 2.032
CD8A CD8a molecule 2.023
BRAF B-Raf proto-oncogene, serine/threonine kinase 2.02
PLAG1 pleiomorphic adenoma gene 1 2.02
IGF1R insulin-like growth factor 1 receptor 2.011
NCAM1 neural cell adhesion molecule 1 2.008
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.99
PHF1 PHD finger protein 1 1.983
KRT5 keratin 5, type II 1.982
PAX8 paired box 8 1.978
BRCA2 breast cancer 2, early onset 1.978
KRT20 keratin 20, type I 1.978
AFP alpha-fetoprotein 1.969
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 1.968
DAXX death-domain associated protein 1.966
KDR kinase insert domain receptor 1.941
CTAG1B cancer/testis antigen 1B 1.933
PDGFB platelet-derived growth factor beta polypeptide 1.925
PAX7 paired box 7 1.91
CD163 CD163 molecule 1.909
PARP1 poly (ADP-ribose) polymerase 1 1.909
FOXO1 forkhead box O1 1.894
CR2 complement component (3d/Epstein Barr virus) receptor 2 1.88
TERT telomerase reverse transcriptase 1.877
PDCD1 programmed cell death 1 1.871
PTPRC protein tyrosine phosphatase, receptor type, C 1.868
MITF microphthalmia-associated transcription factor 1.867
HEATR3 HEAT repeat containing 3 1.862
CD47 CD47 molecule 1.856
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.842
CSF1R colony stimulating factor 1 receptor 1.838
TSC2 tuberous sclerosis 2 1.836
MYOCD myocardin 1.823
PRAME preferentially expressed antigen in melanoma 1.82
RAD51B RAD51 paralog B 1.819
CD4 CD4 molecule 1.819
RET ret proto-oncogene 1.811
FLT1 fms-related tyrosine kinase 1 1.807
CSF1 colony stimulating factor 1 (macrophage) 1.805
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 1.805
MEAF6 MYST/Esa1-associated factor 6 1.799
TGFB1 transforming growth factor, beta 1 1.784
SIRPA signal-regulatory protein alpha 1.783
FGFR1 fibroblast growth factor receptor 1 1.782
PXDN peroxidasin 1.779
PXDNL peroxidasin-like 1.775
ATM ATM serine/threonine kinase 1.775
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 1.746
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 1.744
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 1.74
MSH2 mutS homolog 2 1.74
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.739
SATB2 SATB homeobox 2 1.736
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase 1.732
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 1.722
NUTM2B NUT family member 2B 1.721
NT5DC2 5'-nucleotidase domain containing 2 1.72
NCOA2 nuclear receptor coactivator 2 1.714
CHGA chromogranin A 1.711
EGF epidermal growth factor 1.698
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.696
FLT4 fms-related tyrosine kinase 4 1.695
IDO1 indoleamine 2,3-dioxygenase 1 1.691
PCNA proliferating cell nuclear antigen 1.688
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.684
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 1.684
HDAC9 histone deacetylase 9 1.683
MLH1 mutL homolog 1 1.683
FN1 fibronectin 1 1.682
IFNG interferon, gamma 1.679
SLMAP sarcolemma associated protein 1.672
MSH6 mutS homolog 6 1.669
ARID1A AT rich interactive domain 1A (SWI-like) 1.668
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 1.668
CDK8 cyclin-dependent kinase 8 1.665
COL1A1 collagen, type I, alpha 1 1.663
CCNB3 cyclin B3 1.661
HRAS Harvey rat sarcoma viral oncogene homolog 1.66
ALB albumin 1.658
KRT8 keratin 8, type II 1.657
TPM3 tropomyosin 3 1.655
CD44 CD44 molecule (Indian blood group) 1.65
CDK6 cyclin-dependent kinase 6 1.639
ETV6 ets variant 6 1.628
NR4A3 nuclear receptor subfamily 4, group A, member 3 1.624
MET MET proto-oncogene, receptor tyrosine kinase 1.617
PDCD1LG2 programmed cell death 1 ligand 2 1.616
H3-3B H3.3 histone B 1.613
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.613
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 1.608
IGF1 insulin-like growth factor 1 (somatomedin C) 1.608
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 1.6
AURKA aurora kinase A 1.593
ACTB actin, beta 1.592
KRT19 keratin 19, type I 1.59
MAGEA4 melanoma antigen family A4 1.588
IL2 interleukin 2 1.579
CSF3 colony stimulating factor 3 (granulocyte) 1.572
H3C12 H3 clustered histone 12 1.569
NF2 neurofibromin 2 (merlin) 1.569
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 1.563
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.56
CCNE1 cyclin E1 1.558
CHEK2 checkpoint kinase 2 1.558
ACTG2 actin, gamma 2, smooth muscle, enteric 1.557
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 1.556
RB1 retinoblastoma 1 1.552
HAVCR2 hepatitis A virus cellular receptor 2 1.551
CAMTA1 calmodulin binding transcription activator 1 1.547
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 1.547
JUN jun proto-oncogene 1.546
IL6 interleukin 6 1.546
SMTN smoothelin 1.545
AXL AXL receptor tyrosine kinase 1.543
GFAP glial fibrillary acidic protein 1.543
TPM4 tropomyosin 4 1.539
FGF2 fibroblast growth factor 2 (basic) 1.535
TNF tumor necrosis factor 1.535
FRS2 fibroblast growth factor receptor substrate 2 1.535
TSPAN31 tetraspanin 31 1.532
LAG3 lymphocyte-activation gene 3 1.531
H3-4 H3.4 histone, cluster member 1.531
GLI1 GLI family zinc finger 1 1.527
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.525
H3C13 H3 clustered histone 13 1.525
TP63 tumor protein p63 1.522
H3-5 H3.5 histone 1.521
GATA3 GATA binding protein 3 1.516
RANBP2 RAN binding protein 2 1.512
BIRC5 baculoviral IAP repeat containing 5 1.508
MMP2 matrix metallopeptidase 2 1.505
BRD8 bromodomain containing 8 1.503
PDPN podoplanin 1.503
CRP C-reactive protein, pentraxin-related 1.503
CREB3L2 cAMP responsive element binding protein 3-like 2 1.502
KITLG KIT ligand 1.5
CDK2 cyclin-dependent kinase 2 1.5
BCORL1 BCL6 corepressor-like 1 1.498
CLTC clathrin, heavy chain (Hc) 1.495
POLE polymerase (DNA directed), epsilon, catalytic subunit 1.494
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.493
FGFR3 fibroblast growth factor receptor 3 1.49
RAD51 RAD51 recombinase 1.49
TAGLN transgelin 1.487
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 1.485
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF 1.482
FOXP3 forkhead box P3 1.48
RHD Rh blood group, D antigen 1.479
CNN1 calponin 1, basic, smooth muscle 1.478
KLK3 kallikrein-related peptidase 3 1.476
YAP1 Yes-associated protein 1 1.475
MUC4 mucin 4, cell surface associated 1.472
CHEK1 checkpoint kinase 1 1.467
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 1.462
KRT18 keratin 18, type I 1.461
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 1.458
CAPN6 calpain 6 1.457
CDX2 caudal type homeobox 2 1.452
MYH11 myosin, heavy chain 11, smooth muscle 1.451
MUC1 mucin 1, cell surface associated 1.45
CCNC cyclin C 1.45
ARL4C ADP-ribosylation factor-like 4C 1.447
JAK2 Janus kinase 2 1.445
JAK1 Janus kinase 1 1.445
COL4A6 collagen, type IV, alpha 6 1.444
TAGLN3 transgelin 3 1.443
TCHP trichoplein, keratin filament binding 1.438
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 1.436
HLA-A major histocompatibility complex, class I, A 1.434
AR androgen receptor 1.434
SNAI2 snail family zinc finger 2 1.432
LMOD1 leiomodin 1 (smooth muscle) 1.431
NKX2-1 NK2 homeobox 1 1.43
CTSK cathepsin K 1.429
INS insulin 1.422
THBS1 thrombospondin 1 1.422
VIM vimentin 1.419
CA9 carbonic anhydrase IX 1.415
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 1.414
SNAI1 snail family zinc finger 1 1.411
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 1.41
VGLL3 vestigial-like family member 3 1.408
DES desmin 1.402
MAPK3 mitogen-activated protein kinase 3 1.399
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.397
FLT3 fms-related tyrosine kinase 3 1.396
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 1.396
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.395
IL10 interleukin 10 1.395
DICER1 dicer 1, ribonuclease type III 1.388
DUX4 double homeobox 4 1.385
WWTR1 WW domain containing transcription regulator 1 1.382
SOX2 SRY (sex determining region Y)-box 2 1.382
CD248 CD248 molecule, endosialin 1.381
CXCL8 chemokine (C-X-C motif) ligand 8 1.381
MCAM melanoma cell adhesion molecule 1.381
CCND2 cyclin D2 1.38
NOTCH1 notch 1 1.38
PGM1 phosphoglucomutase 1 1.379
ITGA7 integrin, alpha 7 1.378
MMP9 matrix metallopeptidase 9 1.378
TYR tyrosinase 1.376
OVGP1 oviductal glycoprotein 1, 120kDa 1.375
RICTOR RPTOR independent companion of MTOR, complex 2 1.375
PROM1 prominin 1 1.373
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.371
B3GAT1 beta-1,3-glucuronyltransferase 1 1.37
SLITRK4 SLIT and NTRK-like family, member 4 1.368
STAT1 signal transducer and activator of transcription 1, 91kDa 1.365
BAX BCL2-associated X protein 1.361
ATF1 activating transcription factor 1 1.358
MBTD1 mbt domain containing 1 1.356
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.356
POU5F1 POU class 5 homeobox 1 1.355
IGFBP3 insulin-like growth factor binding protein 3 1.355
ETV1 ets variant 1 1.353
MAGEA3 melanoma antigen family A3 1.351
GREB1 growth regulation by estrogen in breast cancer 1 1.351
YEATS4 YEATS domain containing 4 1.35
STK11 serine/threonine kinase 11 1.35
NT5DC4 5'-nucleotidase domain containing 4 1.348
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.348
TOP2A topoisomerase (DNA) II alpha 170kDa 1.348
BCL2L1 BCL2-like 1 1.348
FGFR4 fibroblast growth factor receptor 4 1.347
MYLK myosin light chain kinase 1.34
CCNL2 cyclin L2 1.338
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.337
GID4 GID complex subunit 4 1.337
VGLL2 vestigial-like family member 2 1.337
FLCN folliculin 1.337
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.332
WEE1 WEE1 G2 checkpoint kinase 1.331
CDK1 cyclin-dependent kinase 1 1.331
PBRM1 polybromo 1 1.331
HDAC4 histone deacetylase 4 1.33
CCNB1 cyclin B1 1.329
TAGLN2 transgelin 2 1.324
NANOG Nanog homeobox 1.323
E2F1 E2F transcription factor 1 1.323
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 1.323
CD19 CD19 molecule 1.322
CD1E CD1e molecule 1.321
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.321
TRPS1 trichorhinophalangeal syndrome I 1.32
CD1A CD1a molecule 1.319
ANXA5 annexin A5 1.317
AURKB aurora kinase B 1.314
RAD51D RAD51 paralog D 1.313
CCL2 chemokine (C-C motif) ligand 2 1.313
KCNIP4 Kv channel interacting protein 4 1.312
AMHR2 anti-Mullerian hormone receptor, type II 1.311
COL4A5 collagen, type IV, alpha 5 1.311
FSCN1 fascin actin-bundling protein 1 1.31
EML4 echinoderm microtubule associated protein like 4 1.308
ASS1 argininosuccinate synthase 1 1.306
CD1B CD1b molecule 1.303
NES nestin 1.3
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 1.3
FOXM1 forkhead box M1 1.296
MEF2D myocyte enhancer factor 2D 1.295
SHH sonic hedgehog 1.295
PRKCQ protein kinase C, theta 1.29
EPCAM epithelial cell adhesion molecule 1.288
CD86 CD86 molecule 1.286
PTCH1 patched 1 1.286
KANSL1 KAT8 regulatory NSL complex subunit 1 1.286
TIGIT T cell immunoreceptor with Ig and ITIM domains 1.286
CREB3L1 cAMP responsive element binding protein 3-like 1 1.284
CD1C CD1c molecule 1.283
RAD51C RAD51 paralog C 1.283
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 1.281
PLK1 polo-like kinase 1 1.28
CD1D CD1d molecule 1.276
CD80 CD80 molecule 1.274
MYF5 myogenic factor 5 1.272
FGF3 fibroblast growth factor 3 1.272
MEN1 multiple endocrine neoplasia I 1.271
MAML3 mastermind-like 3 (Drosophila) 1.27
FGF7 fibroblast growth factor 7 1.27
MAP2K1 mitogen-activated protein kinase kinase 1 1.269
KAT6B K(lysine) acetyltransferase 6B 1.269
FGF4 fibroblast growth factor 4 1.268
ZEB1 zinc finger E-box binding homeobox 1 1.267
ERCC5 excision repair cross-complementation group 5 1.266
COL6A3 collagen, type VI, alpha 3 1.265
ENG endoglin 1.265
USP6 ubiquitin specific peptidase 6 1.264
FGF10 fibroblast growth factor 10 1.264
NKX2-2 NK2 homeobox 2 1.261
EZHIP EZH inhibitory protein 1.261
ETV4 ets variant 4 1.26
TYRO3 TYRO3 protein tyrosine kinase 1.258
GPC3 glypican 3 1.257
FOS FBJ murine osteosarcoma viral oncogene homolog 1.255
EP300 E1A binding protein p300 1.254
MYF6 myogenic factor 6 (herculin) 1.252
MSR1 macrophage scavenger receptor 1 1.251
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.25
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.249
CCNA2 cyclin A2 1.249
SMAD4 SMAD family member 4 1.248
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 1.247
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 1.246
FGF18 fibroblast growth factor 18 1.246
PRKDC protein kinase, DNA-activated, catalytic polypeptide 1.243
IFNA1 interferon, alpha 1 1.243
PTPRB protein tyrosine phosphatase, receptor type, B 1.243
BMI1 BMI1 proto-oncogene, polycomb ring finger 1.242
TSPAN7 tetraspanin 7 1.241
TNS1 tensin 1 1.24
SSX3 synovial sarcoma, X breakpoint 3 1.239
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 1.239
IRF1 interferon regulatory factor 1 1.238
COMMD3-BMI1 COMMD3-BMI1 readthrough 1.238
FGF8 fibroblast growth factor 8 (androgen-induced) 1.237
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.233
PALB2 partner and localizer of BRCA2 1.231
PDGFA platelet-derived growth factor alpha polypeptide 1.231
CD276 CD276 molecule 1.229
TNNT1 troponin T type 1 (skeletal, slow) 1.227
ALPP alkaline phosphatase, placental 1.225
BIVM-ERCC5 BIVM-ERCC5 readthrough 1.225
MGMT O-6-methylguanine-DNA methyltransferase 1.223
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 1.221
B2M beta-2-microglobulin 1.219
EPAS1 endothelial PAS domain protein 1 1.219
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 1.219
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.216
NOTCH2 notch 2 1.216
PTGER4 prostaglandin E receptor 4 (subtype EP4) 1.211
CCND3 cyclin D3 1.208
TSPAN10 tetraspanin 10 1.207
GSK3B glycogen synthase kinase 3 beta 1.206
FGF6 fibroblast growth factor 6 1.205
FGF16 fibroblast growth factor 16 1.205
PPARG peroxisome proliferator-activated receptor gamma 1.203
RECQL4 RecQ protein-like 4 1.202
FGF17 fibroblast growth factor 17 1.201
LMNA lamin A/C 1.199
TGFA transforming growth factor, alpha 1.198
NGFR nerve growth factor receptor 1.198
SEC31A SEC31 homolog A (S. cerevisiae) 1.198
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.197
SST somatostatin 1.196
NAV2 neuron navigator 2 1.196
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 1.196
FGF20 fibroblast growth factor 20 1.196
PTK2 protein tyrosine kinase 2 1.195
TDO2 tryptophan 2,3-dioxygenase 1.194
FOXL2 forkhead box L2 1.193
FGF22 fibroblast growth factor 22 1.193
CTAG2 cancer/testis antigen 2 1.192
SETD2 SET domain containing 2 1.191
FGF5 fibroblast growth factor 5 1.19
BRD4 bromodomain containing 4 1.189
HDAC1 histone deacetylase 1 1.189
IL1B interleukin 1, beta 1.188
ERBB4 erb-b2 receptor tyrosine kinase 4 1.187
CD28 CD28 molecule 1.185
FLI1 Fli-1 proto-oncogene, ETS transcription factor 1.184
SDC1 syndecan 1 1.183
CDH17 cadherin 17, LI cadherin (liver-intestine) 1.182
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.181
BET1L Bet1 golgi vesicular membrane trafficking protein-like 1.181
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.181
FGF9 fibroblast growth factor 9 1.181
MDM4 MDM4, p53 regulator 1.18
NAPSA napsin A aspartic peptidase 1.179
NUTM1 NUT midline carcinoma, family member 1 1.178
LGALS3 lectin, galactoside-binding, soluble, 3 1.176
XPO1 exportin 1 1.176
CYCS cytochrome c, somatic 1.175
SALL4 spalt-like transcription factor 4 1.172
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 1.172
RORB RAR-related orphan receptor B 1.172
CREB1 cAMP responsive element binding protein 1 1.168
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2 1.168
GTSE1 G-2 and S-phase expressed 1 1.167
SRF serum response factor (c-fos serum response element-binding transcription factor) 1.165
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.164
PTPN11 protein tyrosine phosphatase, non-receptor type 11 1.163
STMN1 stathmin 1 1.162
ERBB3 erb-b2 receptor tyrosine kinase 3 1.159
CXCR4 chemokine (C-X-C motif) receptor 4 1.157
FBLIM1 filamin binding LIM protein 1 1.156
PAX5 paired box 5 1.156
FGFR2 fibroblast growth factor receptor 2 1.154
FANCA Fanconi anemia, complementation group A 1.153
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.152
ARG1 arginase 1 1.152
MAP2K4 mitogen-activated protein kinase kinase 4 1.151
WNT5A wingless-type MMTV integration site family, member 5A 1.151
CD40 CD40 molecule, TNF receptor superfamily member 5 1.15
TEK TEK tyrosine kinase, endothelial 1.15
INSM1 insulinoma-associated 1 1.149
TWIST1 twist family bHLH transcription factor 1 1.149
NT5DC1 5'-nucleotidase domain containing 1 1.148
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 1.147
SPP1 secreted phosphoprotein 1 1.147
KAT2B K(lysine) acetyltransferase 2B 1.144
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.144
RRBP1 ribosome binding protein 1 1.143
VWF von Willebrand factor 1.141
MCL1 myeloid cell leukemia 1 1.141
AKT2 v-akt murine thymoma viral oncogene homolog 2 1.139
RAD50 RAD50 homolog (S. cerevisiae) 1.139
EXT1 exostosin glycosyltransferase 1 1.129
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 1.126
STAG2 stromal antigen 2 1.126
USP18 ubiquitin specific peptidase 18 1.125
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 1.125
MEF2A myocyte enhancer factor 2A 1.123
CASQ2 calsequestrin 2 (cardiac muscle) 1.122
LDHD lactate dehydrogenase D 1.12
IL4 interleukin 4 1.118
CALML3 calmodulin-like 3 1.115
PPP1R36 protein phosphatase 1, regulatory subunit 36 1.115
MRC1 mannose receptor, C type 1 1.114
CALM3 calmodulin 3 (phosphorylase kinase, delta) 1.114
CD79A CD79a molecule, immunoglobulin-associated alpha 1.113
CDK12 cyclin-dependent kinase 12 1.11
CALML4 calmodulin-like 4 1.108
MED13 mediator complex subunit 13 1.108
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 1.108
CALML6 calmodulin-like 6 1.108
ERCC1 excision repair cross-complementation group 1 1.105
CALML5 calmodulin-like 5 1.105
HOOK2 hook microtubule-tethering protein 2 1.105
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 1.103
FGF13 fibroblast growth factor 13 1.103
NCOA1 nuclear receptor coactivator 1 1.103
LEF1 lymphoid enhancer-binding factor 1 1.101
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) 1.097
CDC42 cell division cycle 42 1.097
NCOR1 nuclear receptor corepressor 1 1.095
ERCC2 excision repair cross-complementation group 2 1.094
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.094
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 1.093
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 1.093
CREBBP CREB binding protein 1.092
MAPK1 mitogen-activated protein kinase 1 1.089
ACTA1 actin, alpha 1, skeletal muscle 1.088
NT5DC3 5'-nucleotidase domain containing 3 1.087
CDKN3 cyclin-dependent kinase inhibitor 3 1.087
TFCP2 transcription factor CP2 1.086
BARD1 BRCA1 associated RING domain 1 1.084
FASLG Fas ligand (TNF superfamily, member 6) 1.084
SLC35E3 solute carrier family 35, member E3 1.083
DLEC1 deleted in lung and esophageal cancer 1 1.083
HDAC8 histone deacetylase 8 1.08
BCL6 B-cell CLL/lymphoma 6 1.08
ZNF444 zinc finger protein 444 1.079
RNF223 ring finger protein 223 1.079
GNRHR gonadotropin-releasing hormone receptor 1.078
PDLIM7 PDZ and LIM domain 7 (enigma) 1.078
VEGFC vascular endothelial growth factor C 1.078
NOTCH3 notch 3 1.076
SCYL1 SCY1-like 1 (S. cerevisiae) 1.073
IRS1 insulin receptor substrate 1 1.071
CD70 CD70 molecule 1.068
PLAU plasminogen activator, urokinase 1.068
CDK19 cyclin-dependent kinase 19 1.068
CXCL12 chemokine (C-X-C motif) ligand 12 1.068
CD5 CD5 molecule 1.067
H2AX H2A.X variant histone 1.066
BRD9 bromodomain containing 9 1.065
THY1 Thy-1 cell surface antigen 1.063
CXCL10 chemokine (C-X-C motif) ligand 10 1.061
SUFU suppressor of fused homolog (Drosophila) 1.059
CCN2 cellular communication network factor 2 1.059
POTEF POTE ankyrin domain family, member F 1.058
PLCG1 phospholipase C, gamma 1 1.057
TG thyroglobulin 1.056
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 1.055
KMT2D lysine (K)-specific methyltransferase 2D 1.055
HMGA1 high mobility group AT-hook 1 1.055
GAST gastrin 1.052
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.051
EXT2 exostosin glycosyltransferase 2 1.05
CAV1 caveolin 1, caveolae protein, 22kDa 1.05
CCL5 chemokine (C-C motif) ligand 5 1.049
CD24 CD24 molecule 1.049
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.047
C3ORF62 chromosome 3 open reading frame 62 1.045
PMEL premelanosome protein 1.044
GAS6 growth arrest-specific 6 1.043
LDHA lactate dehydrogenase A 1.041
INSR insulin receptor 1.041
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 1.04
BANF1 barrier to autointegration factor 1 1.038
KRT14 keratin 14, type I 1.038
GINS2 GINS complex subunit 2 (Psf2 homolog) 1.036
KLF4 Kruppel-like factor 4 (gut) 1.034
DNTT DNA nucleotidylexotransferase 1.034
EGR1 early growth response 1 1.033
MSLN mesothelin 1.032
OSCAR osteoclast associated, immunoglobulin-like receptor 1.031
AMACR alpha-methylacyl-CoA racemase 1.03
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 1.029
ROR2 receptor tyrosine kinase-like orphan receptor 2 1.028
PXN paxillin 1.028
PRSS38 protease, serine, 38 1.026
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.024
TP53BP1 tumor protein p53 binding protein 1 1.024
RHOA ras homolog family member A 1.023
RBL2 retinoblastoma-like 2 1.02
AXIN1 axin 1 1.019
PAX2 paired box 2 1.019
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 1.018
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 1.017
MUC16 mucin 16, cell surface associated 1.017
LRRC15 leucine rich repeat containing 15 1.017
TSC1 tuberous sclerosis 1 1.016
KAT2A K(lysine) acetyltransferase 2A 1.016
VSIR V-set immunoregulatory receptor 1.015
PLIN2 perilipin 2 1.014
RBP1 retinol binding protein 1, cellular 1.014
KMT2A lysine (K)-specific methyltransferase 2A 1.014
MELK maternal embryonic leucine zipper kinase 1.014
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 1.013
RUNX2 runt-related transcription factor 2 1.013
PRF1 perforin 1 (pore forming protein) 1.012
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 1.012
CCNA1 cyclin A1 1.011
IDO2 indoleamine 2,3-dioxygenase 2 1.01
C11ORF68 chromosome 11 open reading frame 68 1.009
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 1.009
CKM creatine kinase, muscle 1.009
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 1.008
CCK cholecystokinin 1.007
COPS3 COP9 signalosome subunit 3 1.007
GNAS GNAS complex locus 1.007
JAG1 jagged 1 1.007
MEF2B myocyte enhancer factor 2B 1.004
MFAP5 microfibrillar associated protein 5 1.002
RCN3 reticulocalbin 3, EF-hand calcium binding domain 1.002