Leishmania infection Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-9658195
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Genes

165 proteins participating in the Leishmania infection pathway from the Reactome Pathways 2024 dataset.

Symbol Name
ABI1 abl-interactor 1
ABI2 abl-interactor 2
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACTB actin, beta
ACTG1 actin gamma 1
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
ACTR3 ARP3 actin-related protein 3 homolog (yeast)
ADAM17 ADAM metallopeptidase domain 17
ADCY1 adenylate cyclase 1 (brain)
ADCY2 adenylate cyclase 2 (brain)
ADCY3 adenylate cyclase 3
ADCY4 adenylate cyclase 4
ADCY5 adenylate cyclase 5
ADCY6 adenylate cyclase 6
ADCY7 adenylate cyclase 7
ADCY8 adenylate cyclase 8 (brain)
ADCY9 adenylate cyclase 9
ADORA2B adenosine A2b receptor
AHCYL1 adenosylhomocysteinase-like 1
APP amyloid beta (A4) precursor protein
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa
BAIAP2 BAI1-associated protein 2
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit
BTK Bruton agammaglobulinemia tyrosine kinase
C3 complement component 3
C3AR1 complement component 3a receptor 1
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CASP1 caspase 1, apoptosis-related cysteine peptidase
CD163 CD163 molecule
CD247 CD247 molecule
CD3G CD3g molecule, gamma (CD3-TCR complex)
CDC42 cell division cycle 42
CREB1 cAMP responsive element binding protein 1
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CTSG cathepsin G
CYBA cytochrome b-245, alpha polypeptide
CYFIP1 cytoplasmic FMR1 interacting protein 1
CYFIP2 cytoplasmic FMR1 interacting protein 2
CYSLTR1 cysteinyl leukotriene receptor 1
CYSLTR2 cysteinyl leukotriene receptor 2
DOCK1 dedicator of cytokinesis 1
DPEP1 dipeptidase 1 (renal)
DPEP2 dipeptidase 2
DVL1 dishevelled segment polarity protein 1
DVL2 dishevelled segment polarity protein 2
DVL3 dishevelled segment polarity protein 3
ELMO1 engulfment and cell motility 1
ELMO2 engulfment and cell motility 2
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FGR FGR proto-oncogene, Src family tyrosine kinase
FURIN furin (paired basic amino acid cleaving enzyme)
FYN FYN proto-oncogene, Src family tyrosine kinase
FZD7 frizzled class receptor 7
GGT1 gamma-glutamyltransferase 1
GGT5 gamma-glutamyltransferase 5
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
GNAS GNAS complex locus
GNAT3 guanine nucleotide binding protein, alpha transducing 3
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4
GNB5 guanine nucleotide binding protein (G protein), beta 5
GNG10 guanine nucleotide binding protein (G protein), gamma 10
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GNG12 guanine nucleotide binding protein (G protein), gamma 12
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GNG2 guanine nucleotide binding protein (G protein), gamma 2
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNG5 guanine nucleotide binding protein (G protein), gamma 5
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GNG8 guanine nucleotide binding protein (G protein), gamma 8
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
GRB2 growth factor receptor-bound protein 2
GSDMD gasdermin D
HCK HCK proto-oncogene, Src family tyrosine kinase
HMOX1 heme oxygenase 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
IGH immunoglobulin heavy locus
IGL immunoglobulin lambda locus
IGLL5 immunoglobulin lambda-like polypeptide 5
IL10 interleukin 10
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL6 interleukin 6
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
JUN jun proto-oncogene
LOC102723407 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8
LYN LYN proto-oncogene, Src family tyrosine kinase
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MEFV Mediterranean fever
MYH2 myosin, heavy chain 2, skeletal muscle, adult
MYH9 myosin, heavy chain 9, non-muscle
MYO10 myosin X
MYO1C myosin IC
MYO5A myosin VA (heavy chain 12, myoxin)
MYO9B myosin IXB
NCK1 NCK adaptor protein 1
NCKAP1 NCK-associated protein 1
NCKAP1L NCK-associated protein 1-like
NCKIPSD NCK interacting protein with SH3 domain
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NLRP3 NLR family, pyrin domain containing 3
NOX1 NADPH oxidase 1
NOXA1 NADPH oxidase activator 1
NOXO1 NADPH oxidase organizer 1
NT5E 5'-nucleotidase, ecto (CD73)
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PLCG1 phospholipase C, gamma 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLK2 polo-like kinase 2
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKX protein kinase, X-linked
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1
PTK2 protein tyrosine kinase 2
PYCARD PYD and CARD domain containing
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SUGT1 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
SYK spleen tyrosine kinase
TXN thioredoxin
TXNIP thioredoxin interacting protein
VAV1 vav 1 guanine nucleotide exchange factor
VAV2 vav 2 guanine nucleotide exchange factor
VAV3 vav 3 guanine nucleotide exchange factor
WAS Wiskott-Aldrich syndrome
WASF1 WAS protein family, member 1
WASF2 WAS protein family, member 2
WASF3 WAS protein family, member 3
WASL Wiskott-Aldrich syndrome-like
WIPF1 WAS/WASL interacting protein family, member 1
WIPF2 WAS/WASL interacting protein family, member 2
WIPF3 WAS/WASL interacting protein family, member 3
WNT5A wingless-type MMTV integration site family, member 5A
YES1 YES proto-oncogene 1, Src family tyrosine kinase