Leishmaniasis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description Leishmaniasis is a disease caused by protozoan parasites that belong to the genus Leishmania and is transmitted by the bite of certain species of sand fly (subfamily Phlebotominae). (Experimental Factor Ontology, EFO_0005044)
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Genes

796 genes co-occuring with the disease Leishmaniasis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
LMLN leishmanolysin-like (metallopeptidase M8 family) 3.745
IFNG interferon, gamma 3.432
IL10 interleukin 10 3.257
IL4 interleukin 4 3.173
CD4 CD4 molecule 3.172
TNF tumor necrosis factor 2.988
CD8A CD8a molecule 2.975
IL2 interleukin 2 2.695
HSPA4 heat shock 70kDa protein 4 2.668
IL6 interleukin 6 2.609
IL17A interleukin 17A 2.604
IL1B interleukin 1, beta 2.597
TLR2 toll-like receptor 2 2.589
TGFB1 transforming growth factor, beta 1 2.589
IL13 interleukin 13 2.551
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 2.538
ARG1 arginase 1 2.526
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 2.524
TLR4 toll-like receptor 4 2.492
IL5 interleukin 5 2.472
ALB albumin 2.401
ARG2 arginase 2 2.387
NOS2 nitric oxide synthase 2, inducible 2.387
TLR9 toll-like receptor 9 2.372
FOXP3 forkhead box P3 2.369
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 2.332
MPI mannose phosphate isomerase 2.32
PGD phosphogluconate dehydrogenase 2.301
CD40 CD40 molecule, TNF receptor superfamily member 5 2.299
CXCL10 chemokine (C-X-C motif) ligand 10 2.262
IL1A interleukin 1, alpha 2.234
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 2.224
CD86 CD86 molecule 2.219
MYD88 myeloid differentiation primary response 88 2.199
IL18 interleukin 18 2.196
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 2.192
CD80 CD80 molecule 2.186
TLR3 toll-like receptor 3 2.175
ERV3-1 endogenous retrovirus group 3, member 1 2.173
CCL2 chemokine (C-C motif) ligand 2 2.17
ERVFRD-1 endogenous retrovirus group FRD, member 1 2.169
ERVW-1 endogenous retrovirus group W, member 1 2.157
CCL3 chemokine (C-C motif) ligand 3 2.156
CXCL8 chemokine (C-X-C motif) ligand 8 2.146
KRT26 keratin 26, type I 2.135
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 2.134
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 2.131
TLR7 toll-like receptor 7 2.13
TBX21 T-box 21 2.127
ODC1 ornithine decarboxylase 1 2.123
STAT1 signal transducer and activator of transcription 1, 91kDa 2.114
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 2.103
PXDNL peroxidasin-like 2.098
PXDN peroxidasin 2.098
CXCL9 chemokine (C-X-C motif) ligand 9 2.079
CD1D CD1d molecule 2.076
IFNA1 interferon, alpha 1 2.054
CTSL cathepsin L 2.037
IFNB1 interferon, beta 1, fibroblast 2.012
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 2.008
GAPDH glyceraldehyde-3-phosphate dehydrogenase 2.008
CCL5 chemokine (C-C motif) ligand 5 2.007
PRF1 perforin 1 (pore forming protein) 2.006
IL4R interleukin 4 receptor 1.994
CCR7 chemokine (C-C motif) receptor 7 1.992
NELFCD negative elongation factor complex member C/D 1.989
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.985
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) 1.979
CCL4 chemokine (C-C motif) ligand 4 1.978
CD1C CD1c molecule 1.973
CLEC7A C-type lectin domain family 7, member A 1.972
IL22 interleukin 22 1.965
IL10RA interleukin 10 receptor, alpha 1.956
CD1B CD1b molecule 1.952
SELL selectin L 1.95
CD1A CD1a molecule 1.95
ENTPD8 ectonucleoside triphosphate diphosphohydrolase 8 1.945
CD40LG CD40 ligand 1.941
ANXA5 annexin A5 1.938
CD1E CD1e molecule 1.936
H2BC21 H2B clustered histone 21 1.928
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.912
IFNGR1 interferon gamma receptor 1 1.908
G6PD glucose-6-phosphate dehydrogenase 1.907
CPB1 carboxypeptidase B1 (tissue) 1.894
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.894
PAQR7 progestin and adipoQ receptor family member VII 1.891
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.887
IL12RB1 interleukin 12 receptor, beta 1 1.886
CD69 CD69 molecule 1.884
TPI1 triosephosphate isomerase 1 1.883
CCR2 chemokine (C-C motif) receptor 2 1.882
CD209 CD209 molecule 1.877
IL9 interleukin 9 1.877
PTPRC protein tyrosine phosphatase, receptor type, C 1.874
LAMP1 lysosomal-associated membrane protein 1 1.871
C3 complement component 3 1.868
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.865
IRF1 interferon regulatory factor 1 1.863
CD28 CD28 molecule 1.86
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 1.853
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 1.849
IL27RA interleukin 27 receptor, alpha 1.847
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.843
CD207 CD207 molecule, langerin 1.838
H2AC20 H2A clustered histone 20 1.835
H2AC18 H2A clustered histone 18 1.834
CD19 CD19 molecule 1.832
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 1.83
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1.829
NLRP3 NLR family, pyrin domain containing 3 1.825
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.821
CXCR3 chemokine (C-X-C motif) receptor 3 1.819
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 1.818
MRC1 mannose receptor, C type 1 1.814
CTSB cathepsin B 1.812
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.807
IL15 interleukin 15 1.807
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 1.803
TLR1 toll-like receptor 1 1.793
GPI glucose-6-phosphate isomerase 1.79
CD68 CD68 molecule 1.79
TBL1X transducin (beta)-like 1X-linked 1.79
LONP1 lon peptidase 1, mitochondrial 1.789
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.789
DHFR dihydrofolate reductase 1.787
HPRT1 hypoxanthine phosphoribosyltransferase 1 1.786
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.781
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 1.78
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.78
CTSS cathepsin S 1.778
ACTB actin, beta 1.774
CD276 CD276 molecule 1.766
CRP C-reactive protein, pentraxin-related 1.759
JUN jun proto-oncogene 1.759
CTRB2 chymotrypsinogen B2 1.757
MAPK3 mitogen-activated protein kinase 3 1.756
CTRB1 chymotrypsinogen B1 1.755
CSF1 colony stimulating factor 1 (macrophage) 1.754
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2 1.752
IL12RB2 interleukin 12 receptor, beta 2 1.75
IL3 interleukin 3 1.749
NUTF2 nuclear transport factor 2 1.74
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 1.738
EEF1B2 eukaryotic translation elongation factor 1 beta 2 1.734
GATA3 GATA binding protein 3 1.734
CD274 CD274 molecule 1.733
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.729
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 1.728
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.725
CYCS cytochrome c, somatic 1.724
ICAM1 intercellular adhesion molecule 1 1.72
CD44 CD44 molecule (Indian blood group) 1.719
FDPS farnesyl diphosphate synthase 1.717
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 1.706
ELANE elastase, neutrophil expressed 1.7
GNLY granulysin 1.684
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 1.683
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 1.683
FN1 fibronectin 1 1.677
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.672
CYBB cytochrome b-245, beta polypeptide 1.672
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 1.67
TLR6 toll-like receptor 6 1.668
DSG1 desmoglein 1 1.664
MMP9 matrix metallopeptidase 9 1.662
SRM spermidine synthase 1.661
IDO1 indoleamine 2,3-dioxygenase 1 1.659
CD163 CD163 molecule 1.659
CCL19 chemokine (C-C motif) ligand 19 1.653
SP100 SP100 nuclear antigen 1.65
IFNAR1 interferon (alpha, beta and omega) receptor 1 1.644
CHIT1 chitinase 1 (chitotriosidase) 1.642
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 1.641
CR2 complement component (3d/Epstein Barr virus) receptor 2 1.641
LY75-CD302 LY75-CD302 readthrough 1.638
LY75 lymphocyte antigen 75 1.633
EEF2 eukaryotic translation elongation factor 2 1.633
IL32 interleukin 32 1.63
RACK1 receptor for activated C kinase 1 1.629
FASLG Fas ligand (TNF superfamily, member 6) 1.628
IL7R interleukin 7 receptor 1.624
MPO myeloperoxidase 1.621
DNAH8 dynein, axonemal, heavy chain 8 1.618
SIRT2 sirtuin 2 1.613
IRF8 interferon regulatory factor 8 1.612
EDC4 enhancer of mRNA decapping 4 1.609
IL1R1 interleukin 1 receptor, type I 1.604
DHFR2 dihydrofolate reductase 2 1.603
BCL2 B-cell CLL/lymphoma 2 1.6
IL33 interleukin 33 1.6
RAG1 recombination activating gene 1 1.599
NCAM1 neural cell adhesion molecule 1 1.598
TLR8 toll-like receptor 8 1.597
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 1.596
CTRL chymotrypsin-like 1.587
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 1.584
HMOX1 heme oxygenase 1 1.577
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.573
CXCL2 chemokine (C-X-C motif) ligand 2 1.572
GABARAPL1 GABA(A) receptor-associated protein like 1 1.569
FDFT1 farnesyl-diphosphate farnesyltransferase 1 1.567
TXN thioredoxin 1.567
HLA-A major histocompatibility complex, class I, A 1.567
SYK spleen tyrosine kinase 1.566
LTA lymphotoxin alpha 1.566
CD83 CD83 molecule 1.566
PDCD1LG2 programmed cell death 1 ligand 2 1.565
LAP3 leucine aminopeptidase 3 1.564
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.564
CALM3 calmodulin 3 (phosphorylase kinase, delta) 1.563
IL7 interleukin 7 1.561
CETN1 centrin, EF-hand protein, 1 1.559
SOCS3 suppressor of cytokine signaling 3 1.559
PPIG peptidylprolyl isomerase G (cyclophilin G) 1.558
NMT1 N-myristoyltransferase 1 1.558
CXCR4 chemokine (C-X-C motif) receptor 4 1.557
GSX1 GS homeobox 1 1.557
CD27 CD27 molecule 1.555
NOD2 nucleotide-binding oligomerization domain containing 2 1.554
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.55
LAG3 lymphocyte-activation gene 3 1.55
TLR5 toll-like receptor 5 1.549
INS insulin 1.549
TOP1 topoisomerase (DNA) I 1.548
GABARAPL2 GABA(A) receptor-associated protein-like 2 1.548
AOC3 amine oxidase, copper containing 3 1.547
MAPK1 mitogen-activated protein kinase 1 1.538
CALML3 calmodulin-like 3 1.537
SCARB2 scavenger receptor class B, member 2 1.537
FOS FBJ murine osteosarcoma viral oncogene homolog 1.533
STAT4 signal transducer and activator of transcription 4 1.533
CALML4 calmodulin-like 4 1.532
IRF7 interferon regulatory factor 7 1.531
H1-0 H1.0 linker histone 1.531
CCL21 chemokine (C-C motif) ligand 21 1.529
CALML5 calmodulin-like 5 1.529
CALML6 calmodulin-like 6 1.528
MBL2 mannose-binding lectin (protein C) 2, soluble 1.524
CD36 CD36 molecule (thrombospondin receptor) 1.524
CSF3 colony stimulating factor 3 (granulocyte) 1.524
CCL17 chemokine (C-C motif) ligand 17 1.524
RBM27 RNA binding motif protein 27 1.523
SCARB1 scavenger receptor class B, member 1 1.523
TP53 tumor protein p53 1.521
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 1.519
LTF lactotransferrin 1.516
IL27 interleukin 27 1.516
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) 1.514
CLEC4E C-type lectin domain family 4, member E 1.513
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 1.513
PPARG peroxisome proliferator-activated receptor gamma 1.51
SYT5 synaptotagmin V 1.507
STMN1 stathmin 1 1.506
CXCL11 chemokine (C-X-C motif) ligand 11 1.505
CAMP cathelicidin antimicrobial peptide 1.504
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.5
HAVCR2 hepatitis A virus cellular receptor 2 1.499
IRF3 interferon regulatory factor 3 1.497
IRF5 interferon regulatory factor 5 1.496
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.494
B3GAT1 beta-1,3-glucuronyltransferase 1 1.494
RAB5A RAB5A, member RAS oncogene family 1.491
IL2RA interleukin 2 receptor, alpha 1.491
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 1.488
ADA adenosine deaminase 1.486
GPX3 glutathione peroxidase 3 1.482
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.48
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 1.48
PTS 6-pyruvoyltetrahydropterin synthase 1.479
NMT2 N-myristoyltransferase 2 1.478
GPX2 glutathione peroxidase 2 1.477
SOCS1 suppressor of cytokine signaling 1 1.477
GSR glutathione reductase 1.476
GPX8 glutathione peroxidase 8 (putative) 1.471
GPX5 glutathione peroxidase 5 1.471
SIRT1 sirtuin 1 1.47
TOP1MT topoisomerase (DNA) I, mitochondrial 1.47
CHIA chitinase, acidic 1.468
APRT adenine phosphoribosyltransferase 1.468
CALR calreticulin 1.466
GPX6 glutathione peroxidase 6 1.461
LMTK1 lemur tail kinase 1 1.46
TCHH trichohyalin 1.46
GPX7 glutathione peroxidase 7 1.46
KRT76 keratin 76, type II 1.459
TNFRSF18 tumor necrosis factor receptor superfamily, member 18 1.459
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 1.459
TXNRD3 thioredoxin reductase 3 1.458
CD200 CD200 molecule 1.455
IRAK1 interleukin-1 receptor-associated kinase 1 1.455
HP haptoglobin 1.449
CD5 CD5 molecule 1.448
PTPN1 protein tyrosine phosphatase, non-receptor type 1 1.446
ZKSCAN8 zinc finger with KRAB and SCAN domains 8 1.446
CBS cystathionine-beta-synthase 1.443
CXCL13 chemokine (C-X-C motif) ligand 13 1.443
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 1.441
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 1.439
LY96 lymphocyte antigen 96 1.438
PARS2 prolyl-tRNA synthetase 2, mitochondrial (putative) 1.437
JAK2 Janus kinase 2 1.434
CXCR2 chemokine (C-X-C motif) receptor 2 1.43
DHODH dihydroorotate dehydrogenase (quinone) 1.429
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) 1.425
CCRL2 chemokine (C-C motif) receptor-like 2 1.425
AIM2 absent in melanoma 2 1.422
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 1.419
IFNA2 interferon, alpha 2 1.419
ICAM3 intercellular adhesion molecule 3 1.418
STIP1 stress-induced phosphoprotein 1 1.416
METAP1 methionyl aminopeptidase 1 1.416
CRLF3 cytokine receptor-like factor 3 1.413
ATAD1 ATPase family, AAA domain containing 1 1.412
CCL24 chemokine (C-C motif) ligand 24 1.412
CTXN1 cortexin 1 1.412
MARS1 methionyl-tRNA synthetase 1 1.41
NLRP1 NLR family, pyrin domain containing 1 1.409
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 1.408
SPI1 Spi-1 proto-oncogene 1.408
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 1.405
TFRC transferrin receptor 1.405
ANXA8 annexin A8 1.405
H2BC13 H2B clustered histone 13 1.399
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) 1.398
TREM1 triggering receptor expressed on myeloid cells 1 1.398
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.396
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa 1.395
CCL11 chemokine (C-C motif) ligand 11 1.393
CD38 CD38 molecule 1.391
GGPS1 geranylgeranyl diphosphate synthase 1 1.39
RAG2 recombination activating gene 2 1.388
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 1.383
CD2 CD2 molecule 1.378
H2BC3 H2B clustered histone 3 1.377
JAK1 Janus kinase 1 1.375
REL v-rel avian reticuloendotheliosis viral oncogene homolog 1.372
PDCD1 programmed cell death 1 1.372
TXN2 thioredoxin 2 1.37
H2BC14 H2B clustered histone 14 1.369
SQLE squalene epoxidase 1.368
H2BW1 H2B.W histone 1 1.366
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.366
H2BW2 H2B.W histone 2 1.365
S100A9 S100 calcium binding protein A9 1.365
TNFRSF4 tumor necrosis factor receptor superfamily, member 4 1.365
PREP prolyl endopeptidase 1.362
AQP9 aquaporin 9 1.361
EIF4A2 eukaryotic translation initiation factor 4A2 1.36
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 1.36
RPL23A ribosomal protein L23a 1.359
CCL22 chemokine (C-C motif) ligand 22 1.359
NCF1 neutrophil cytosolic factor 1 1.358
H2BC9 H2B clustered histone 9 1.358
H2BC18 H2B clustered histone 18 1.355
H2BC17 H2B clustered histone 17 1.354
NTSR2 neurotensin receptor 2 1.354
UNC13D unc-13 homolog D (C. elegans) 1.353
SOD1 superoxide dismutase 1, soluble 1.352
H2BC1 H2B clustered histone 1 1.352
H2BC5 H2B clustered histone 5 1.352
MARS2 methionyl-tRNA synthetase 2, mitochondrial 1.351
C5AR1 complement component 5a receptor 1 1.351
CCR6 chemokine (C-C motif) receptor 6 1.35
CCL7 chemokine (C-C motif) ligand 7 1.349
PGK2 phosphoglycerate kinase 2 1.349
SC5D sterol-C5-desaturase 1.348
HDAC9 histone deacetylase 9 1.347
CLEC6A C-type lectin domain family 6, member A 1.346
HSPB6 heat shock protein, alpha-crystallin-related, B6 1.344
PTPN6 protein tyrosine phosphatase, non-receptor type 6 1.344
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 1.343
H2BC4 H2B clustered histone 4 1.343
KLRG1 killer cell lectin-like receptor subfamily G, member 1 1.341
H2BC11 H2B clustered histone 11 1.341
ICOS inducible T-cell co-stimulator 1.34
H2BC15 H2B clustered histone 15 1.339
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 1.338
CA5B carbonic anhydrase VB, mitochondrial 1.337
NTSR1 neurotensin receptor 1 (high affinity) 1.335
NOD1 nucleotide-binding oligomerization domain containing 1 1.334
MINK1 misshapen-like kinase 1 1.334
RORC RAR-related orphan receptor C 1.334
ACOD1 aconitate decarboxylase 1 1.333
APOL1 apolipoprotein L, 1 1.331
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B 1.33
GLB1 galactosidase, beta 1 1.33
CA8 carbonic anhydrase VIII 1.33
CTSD cathepsin D 1.329
H2BC12 H2B clustered histone 12 1.328
IDO2 indoleamine 2,3-dioxygenase 2 1.328
PTPN11 protein tyrosine phosphatase, non-receptor type 11 1.325
F2 coagulation factor II (thrombin) 1.325
EMB embigin 1.325
EIF4A1 eukaryotic translation initiation factor 4A1 1.324
CCR3 chemokine (C-C motif) receptor 3 1.324
CXCL12 chemokine (C-X-C motif) ligand 12 1.322
F3 coagulation factor III (thromboplastin, tissue factor) 1.322
FAS Fas cell surface death receptor 1.321
ACE angiotensin I converting enzyme 1.321
SPAG6 sperm associated antigen 6 1.32
LVRN laeverin 1.32
LGALS3 lectin, galactoside-binding, soluble, 3 1.318
HLA-B major histocompatibility complex, class I, B 1.318
CA13 carbonic anhydrase XIII 1.317
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 1.317
KLRK1 killer cell lectin-like receptor subfamily K, member 1 1.315
CA14 carbonic anhydrase XIV 1.315
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 1.314
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 1.314
TMSB10 thymosin beta 10 1.312
C1QL2 complement component 1, q subcomponent-like 2 1.31
LARS1 leucyl-tRNA synthetase 1 1.309
DHPS deoxyhypusine synthase 1.308
CSF1R colony stimulating factor 1 receptor 1.308
NLRC4 NLR family, CARD domain containing 4 1.308
SPTLC1 serine palmitoyltransferase, long chain base subunit 1 1.306
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 1.304
ANKRD49 ankyrin repeat domain 49 1.304
DICER1 dicer 1, ribonuclease type III 1.303
GBP2 guanylate binding protein 2, interferon-inducible 1.301
NFE2L2 nuclear factor, erythroid 2-like 2 1.301
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.3
CXCR5 chemokine (C-X-C motif) receptor 5 1.3
B2M beta-2-microglobulin 1.3
SPTLC3 serine palmitoyltransferase, long chain base subunit 3 1.3
AQP7 aquaporin 7 1.298
IFNA17 interferon, alpha 17 1.295
KRT28 keratin 28, type I 1.294
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.293
CISH cytokine inducible SH2-containing protein 1.293
KDR kinase insert domain receptor 1.293
CA7 carbonic anhydrase VII 1.292
RPS3A ribosomal protein S3A 1.291
C1QB complement component 1, q subcomponent, B chain 1.291
IRF4 interferon regulatory factor 4 1.289
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa 1.288
LCN2 lipocalin 2 1.288
CCS copper chaperone for superoxide dismutase 1.288
SIRPA signal-regulatory protein alpha 1.288
CCR1 chemokine (C-C motif) receptor 1 1.288
TYR tyrosinase 1.287
CX3CR1 chemokine (C-X3-C motif) receptor 1 1.287
TYRP1 tyrosinase-related protein 1 1.285
PRTN3 proteinase 3 1.284
CA1 carbonic anhydrase I 1.283
UFM1 ubiquitin-fold modifier 1 1.282
CXCL5 chemokine (C-X-C motif) ligand 5 1.282
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 1.28
TOLLIP toll interacting protein 1.276
PPA1 pyrophosphatase (inorganic) 1 1.274
GBP5 guanylate binding protein 5 1.274
ISG15 ISG15 ubiquitin-like modifier 1.271
LYN LYN proto-oncogene, Src family tyrosine kinase 1.27
VAMP8 vesicle-associated membrane protein 8 1.269
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.267
LYST lysosomal trafficking regulator 1.266
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 1.262
STX11 syntaxin 11 1.262
IFNA13 interferon, alpha 13 1.262
EGFR epidermal growth factor receptor 1.262
FPR2 formyl peptide receptor 2 1.261
IL23A interleukin 23, alpha subunit p19 1.26
IL17RA interleukin 17 receptor A 1.26
IFNA4 interferon, alpha 4 1.259
AQP2 aquaporin 2 (collecting duct) 1.259
ASCL2 achaete-scute family bHLH transcription factor 2 1.256
CCL20 chemokine (C-C motif) ligand 20 1.256
BAX BCL2-associated X protein 1.255
CA5A carbonic anhydrase VA, mitochondrial 1.254
RTN4IP1 reticulon 4 interacting protein 1 1.253
ACHE acetylcholinesterase (Yt blood group) 1.251
H4C7 H4 clustered histone 7 1.251
MAPK14 mitogen-activated protein kinase 14 1.251
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 1.251
IL17F interleukin 17F 1.248
ACE2 angiotensin I converting enzyme 2 1.247
CPB2 carboxypeptidase B2 (plasma) 1.245
KNG1 kininogen 1 1.243
LOX lysyl oxidase 1.241
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 1.238
FCN1 ficolin (collagen/fibrinogen domain containing) 1 1.237
LCK LCK proto-oncogene, Src family tyrosine kinase 1.235
CIITA class II, major histocompatibility complex, transactivator 1.232
STAT2 signal transducer and activator of transcription 2, 113kDa 1.231
IRAK4 interleukin-1 receptor-associated kinase 4 1.231
C4A complement component 4A (Rodgers blood group) 1.231
H4C6 H4 clustered histone 6 1.229
RRAGC Ras-related GTP binding C 1.228
AARS1 alanyl-tRNA synthetase 1 1.228
CA3 carbonic anhydrase III 1.225
CA2 carbonic anhydrase II 1.225
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 1.224
ATP7A ATPase, Cu++ transporting, alpha polypeptide 1.224
GALP galanin-like peptide 1.223
TAT tyrosine aminotransferase 1.223
STAT5A signal transducer and activator of transcription 5A 1.223
NISCH nischarin 1.223
LARS2 leucyl-tRNA synthetase 2, mitochondrial 1.222
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.221
IFNA5 interferon, alpha 5 1.218
OR56B4 olfactory receptor, family 56, subfamily B, member 4 1.217
PRR36 proline rich 36 1.216
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.215
CXCR1 chemokine (C-X-C motif) receptor 1 1.214
PFN4 profilin family, member 4 1.214
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa 1.212
HLA-DRA major histocompatibility complex, class II, DR alpha 1.212
PFN3 profilin 3 1.209
PDXK pyridoxal (pyridoxine, vitamin B6) kinase 1.208
TYROBP TYRO protein tyrosine kinase binding protein 1.206
IFNA6 interferon, alpha 6 1.206
IFNA21 interferon, alpha 21 1.206
ATG5 autophagy related 5 1.205
GBP1 guanylate binding protein 1, interferon-inducible 1.205
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.204
IFNA14 interferon, alpha 14 1.2
IFNA7 interferon, alpha 7 1.2
TSLP thymic stromal lymphopoietin 1.199
MNDA myeloid cell nuclear differentiation antigen 1.199
INHA inhibin, alpha 1.199
SELE selectin E 1.199
IFIH1 interferon induced with helicase C domain 1 1.198
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5 1.195
AMY2A amylase, alpha 2A (pancreatic) 1.195
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 1.194
PRDX2 peroxiredoxin 2 1.194
CTSG cathepsin G 1.191
NME2 NME/NM23 nucleoside diphosphate kinase 2 1.19
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 1.19
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 1.19
AHR aryl hydrocarbon receptor 1.19
IGF1 insulin-like growth factor 1 (somatomedin C) 1.188
VCAM1 vascular cell adhesion molecule 1 1.187
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 1.186
LMTK2 lemur tyrosine kinase 2 1.185
EGF epidermal growth factor 1.185
IFNA8 interferon, alpha 8 1.185
CD3E CD3e molecule, epsilon (CD3-TCR complex) 1.184
IL1RN interleukin 1 receptor antagonist 1.184
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 1.182
BCL2L1 BCL2-like 1 1.182
IFNA16 interferon, alpha 16 1.18
IFNA10 interferon, alpha 10 1.179
H3-4 H3.4 histone, cluster member 1.178
HDAC1 histone deacetylase 1 1.177
APOA1 apolipoprotein A-I 1.177
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 1.176
BECN1 beclin 1, autophagy related 1.175
NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit 1.174
CCL8 chemokine (C-C motif) ligand 8 1.174
IL23R interleukin 23 receptor 1.173
ADCY10 adenylate cyclase 10 (soluble) 1.168
H3C12 H3 clustered histone 12 1.167
ALOX5 arachidonate 5-lipoxygenase 1.167
GOLPH3 golgi phosphoprotein 3 (coat-protein) 1.166
BATF3 basic leucine zipper transcription factor, ATF-like 3 1.166
LEP leptin 1.164
CDC42 cell division cycle 42 1.164
H3-5 H3.5 histone 1.163
CD200R1 CD200 receptor 1 1.162
PLG plasminogen 1.162
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 1.162
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.162
CA6 carbonic anhydrase VI 1.16
PNP purine nucleoside phosphorylase 1.16
TLR10 toll-like receptor 10 1.157
ATF3 activating transcription factor 3 1.157
BCHE butyrylcholinesterase 1.157
IL6R interleukin 6 receptor 1.155
DSG3 desmoglein 3 1.154
STAT5B signal transducer and activator of transcription 5B 1.154
STXBP2 syntaxin binding protein 2 1.153
C4B complement component 4B (Chido blood group) 1.152
CD300A CD300a molecule 1.152
DUSP1 dual specificity phosphatase 1 1.15
C3AR1 complement component 3a receptor 1 1.149
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 1.149
MAVS mitochondrial antiviral signaling protein 1.148
AMY1B amylase, alpha 1B (salivary) 1.148
AMY2B amylase, alpha 2B (pancreatic) 1.147
PLEK pleckstrin 1.144
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific 1.143
BTK Bruton agammaglobulinemia tyrosine kinase 1.142
H3C13 H3 clustered histone 13 1.141
ADGRL3 adhesion G protein-coupled receptor L3 1.141
UNC93B1 unc-93 homolog B1 (C. elegans) 1.141
IRF2 interferon regulatory factor 2 1.14
IL21R interleukin 21 receptor 1.139
H3-3B H3.3 histone B 1.138
TYK2 tyrosine kinase 2 1.138
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 1.137
CD63 CD63 molecule 1.137
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.137
CA12 carbonic anhydrase XII 1.137
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 1.137
MAPK4 mitogen-activated protein kinase 4 1.136
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 1.136
NCF2 neutrophil cytosolic factor 2 1.135
PRKCA protein kinase C, alpha 1.135
HCK HCK proto-oncogene, Src family tyrosine kinase 1.134
ENDOG endonuclease G 1.134
NT5E 5'-nucleotidase, ecto (CD73) 1.133
NCF4 neutrophil cytosolic factor 4, 40kDa 1.133
GLO1 glyoxalase I 1.133
CREB1 cAMP responsive element binding protein 1 1.132
FES FES proto-oncogene, tyrosine kinase 1.131
CDK1 cyclin-dependent kinase 1 1.131
CLEC9A C-type lectin domain family 9, member A 1.131
LTB lymphotoxin beta (TNF superfamily, member 3) 1.131
MMP2 matrix metallopeptidase 2 1.129
GLRX glutaredoxin (thioltransferase) 1.129
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 1.129
CASP5 caspase 5, apoptosis-related cysteine peptidase 1.127
OGA O-GlcNAcase 1.127
LMAN1 lectin, mannose-binding, 1 1.126
CD160 CD160 molecule 1.124
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.124
ISYNA1 inositol-3-phosphate synthase 1 1.123
C1QA complement component 1, q subcomponent, A chain 1.123
TIMP1 TIMP metallopeptidase inhibitor 1 1.123
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.121
CD48 CD48 molecule 1.12
AGMO alkylglycerol monooxygenase 1.12
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 1.119
HAMP hepcidin antimicrobial peptide 1.119
EPO erythropoietin 1.117
ACKR2 atypical chemokine receptor 2 1.116
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 1.115
HLA-C major histocompatibility complex, class I, C 1.115
PKM pyruvate kinase, muscle 1.113
LGALS9 lectin, galactoside-binding, soluble, 9 1.112
ANKLE1 ankyrin repeat and LEM domain containing 1 1.112
RPS12 ribosomal protein S12 1.112
RPIA ribose 5-phosphate isomerase A 1.112
C1S complement component 1, s subcomponent 1.111
MYH14 myosin, heavy chain 14, non-muscle 1.111
PGK1 phosphoglycerate kinase 1 1.11
LAMP2 lysosomal-associated membrane protein 2 1.109
MON2 MON2 homolog (S. cerevisiae) 1.109
FPR1 formyl peptide receptor 1 1.108
ADSL adenylosuccinate lyase 1.108
APOE apolipoprotein E 1.108
IL13RA1 interleukin 13 receptor, alpha 1 1.108
HPGDS hematopoietic prostaglandin D synthase 1.108
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 1.107
FCN3 ficolin (collagen/fibrinogen domain containing) 3 1.106
CD9 CD9 molecule 1.106
PRDM1 PR domain containing 1, with ZNF domain 1.105
PEX19 peroxisomal biogenesis factor 19 1.104
MPPE1 metallophosphoesterase 1 1.103
SDC1 syndecan 1 1.103
BCR breakpoint cluster region 1.103
UFSP1 UFM1-specific peptidase 1 (non-functional) 1.102
ESR1 estrogen receptor 1 1.102
CA4 carbonic anhydrase IV 1.102
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 1.102
RAD51 RAD51 recombinase 1.101
TUB tubby bipartite transcription factor 1.1
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.098
SMS spermine synthase 1.097
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4 1.096
OR10H5 olfactory receptor, family 10, subfamily H, member 5 1.096
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 1.094
PRSS3 protease, serine, 3 1.094
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 1.093
PTGES prostaglandin E synthase 1.093
POTEF POTE ankyrin domain family, member F 1.091
MAPK8 mitogen-activated protein kinase 8 1.091
GSK3B glycogen synthase kinase 3 beta 1.09
IL4I1 interleukin 4 induced 1 1.09
KLRD1 killer cell lectin-like receptor subfamily D, member 1 1.089
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 1.089
ANXA1 annexin A1 1.088
CXCL3 chemokine (C-X-C motif) ligand 3 1.087
TCF15 transcription factor 15 (basic helix-loop-helix) 1.087
UPRT uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae) 1.086
CD247 CD247 molecule 1.086
SLCO6A1 solute carrier organic anion transporter family, member 6A1 1.085
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) 1.085
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.084
YARS1 tyrosyl-tRNA synthetase 1 1.081
RAB27A RAB27A, member RAS oncogene family 1.081
CYB5B cytochrome b5 type B (outer mitochondrial membrane) 1.081
IL24 interleukin 24 1.081
JAK3 Janus kinase 3 1.08
CD302 CD302 molecule 1.08
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.079
PDPN podoplanin 1.079
RETNLB resistin like beta 1.078
DOHH deoxyhypusine hydroxylase/monooxygenase 1.078
PPEF1 protein phosphatase, EF-hand calcium binding domain 1 1.078
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.075
EIF4E eukaryotic translation initiation factor 4E 1.075
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.071
DLD dihydrolipoamide dehydrogenase 1.069
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.069
MMP1 matrix metallopeptidase 1 1.069
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 1.068
PFN1 profilin 1 1.068
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.067
IFI16 interferon, gamma-inducible protein 16 1.067
APP amyloid beta (A4) precursor protein 1.067
KLRB1 killer cell lectin-like receptor subfamily B, member 1 1.064
GLYATL1 glycine-N-acyltransferase-like 1 1.064
NKG7 natural killer cell granule protein 7 1.063
TPT1 tumor protein, translationally-controlled 1 1.062
NLRP12 NLR family, pyrin domain containing 12 1.061
POLI polymerase (DNA directed) iota 1.06
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.059
TICAM1 toll-like receptor adaptor molecule 1 1.059
CCL1 chemokine (C-C motif) ligand 1 1.058
CSF3R colony stimulating factor 3 receptor (granulocyte) 1.058
CYB5A cytochrome b5 type A (microsomal) 1.057
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1.057
PRSS33 protease, serine, 33 1.056
CGAS cyclic GMP-AMP synthase 1.055
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.055
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial 1.055
GBP6 guanylate binding protein family, member 6 1.054
STX7 syntaxin 7 1.054
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.052
STX5 syntaxin 5 1.052
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) 1.051
IRF9 interferon regulatory factor 9 1.05
CDK12 cyclin-dependent kinase 12 1.049
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) 1.048
XDH xanthine dehydrogenase 1.048
GYPA glycophorin A (MNS blood group) 1.047
S100A12 S100 calcium binding protein A12 1.046
GSDMD gasdermin D 1.044
SLPI secretory leukocyte peptidase inhibitor 1.043
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 1.042
HBD hemoglobin, delta 1.042
HARS2 histidyl-tRNA synthetase 2, mitochondrial 1.039
PRKG1 protein kinase, cGMP-dependent, type I 1.039
HARS1 histidyl-tRNA synthetase 1 1.037
LINS1 lines homolog 1 1.037
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 1.036
BRD3OS BRD3 opposite strand 1.035
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1 1.033
DPP3 dipeptidyl-peptidase 3 1.032
IFNL1 interferon, lambda 1 1.031
BACE1 beta-site APP-cleaving enzyme 1 1.031
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 1.03
PLEK2 pleckstrin 2 1.03
MAP2K3 mitogen-activated protein kinase kinase 3 1.03
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.029
LBR lamin B receptor 1.028
CCR8 chemokine (C-C motif) receptor 8 1.028
HLA-G major histocompatibility complex, class I, G 1.027
IL16 interleukin 16 1.026
CD34 CD34 molecule 1.026
AGO1 argonaute RISC catalytic component 1 1.025
PRSS1 protease, serine, 1 (trypsin 1) 1.025
IFNAR2 interferon (alpha, beta and omega) receptor 2 1.024
CXCR6 chemokine (C-X-C motif) receptor 6 1.024
ORM2 orosomucoid 2 1.023
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 1.021
TBK1 TANK-binding kinase 1 1.021
ORM1 orosomucoid 1 1.021
ACO2 aconitase 2, mitochondrial 1.021
CD53 CD53 molecule 1.02
ESCO1 establishment of sister chromatid cohesion N-acetyltransferase 1 1.02
HTN3 histatin 3 1.019
ANAPC16 anaphase promoting complex subunit 16 1.019
C1R complement component 1, r subcomponent 1.019
THBS2 thrombospondin 2 1.018
PECAM1 platelet/endothelial cell adhesion molecule 1 1.017
CD79A CD79a molecule, immunoglobulin-associated alpha 1.016
HBB hemoglobin, beta 1.016
CLEC4D C-type lectin domain family 4, member D 1.016
MCL1 myeloid cell leukemia 1 1.015
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 1.014
NOS3 nitric oxide synthase 3 (endothelial cell) 1.011
LTB4R leukotriene B4 receptor 1.011
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.011
MGAM maltase-glucoamylase 1.01
CRK v-crk avian sarcoma virus CT10 oncogene homolog 1.009
GOLGA8K golgin A8 family, member K 1.009
NCR1 natural cytotoxicity triggering receptor 1 1.009
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 1.009
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 1.008
IL1R2 interleukin 1 receptor, type II 1.005
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F 1.005
ALPI alkaline phosphatase, intestinal 1.005
CX3CL1 chemokine (C-X3-C motif) ligand 1 1.004
IL2RG interleukin 2 receptor, gamma 1.004
GLUD1 glutamate dehydrogenase 1 1.004
CST3 cystatin C 1.003
KRTAP9-1 keratin associated protein 9-1 1.003
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.002
BST2 bone marrow stromal cell antigen 2 1.002
TAC1 tachykinin, precursor 1 1.001
CD47 CD47 molecule 1.001
ACO1 aconitase 1, soluble 1.0