Leishmaniasis Gene Set

Dataset KEGG Pathways 2026
Category structural or functional annotations
Type pathway
Description Leishmaniasis is a disease caused by protozoan parasites that belong to the genus Leishmania and is transmitted by the bite of certain species of sand fly (subfamily Phlebotominae). (Experimental Factor Ontology, EFO_0005044)
External Link https://www.kegg.jp/entry/hsa05140
Similar Terms
Downloads & Tools

Genes

76 proteins participating in the Leishmaniasis pathway from the KEGG Pathways 2026 dataset.

Symbol Name
C3 complement component 3
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CR1L complement component (3b/4b) receptor 1-like
CYBA cytochrome b-245, alpha polypeptide
CYBB cytochrome b-245, beta polypeptide
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FOS FBJ murine osteosarcoma viral oncogene homolog
HLA-DMA major histocompatibility complex, class II, DM alpha
HLA-DMB major histocompatibility complex, class II, DM beta
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DOB major histocompatibility complex, class II, DO beta
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IL10 interleukin 10
IL12A interleukin 12A
IL12B interleukin 12B
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL4 interleukin 4
IRAK1 interleukin-1 receptor-associated kinase 1
IRAK4 interleukin-1 receptor-associated kinase 4
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
JAK1 Janus kinase 1
JAK2 Janus kinase 2
JUN jun proto-oncogene
KCNH8 potassium channel, voltage gated eag related subfamily H, member 8
LOC102724971 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8
LOC124905743 low affinity immunoglobulin gamma Fc region receptor III-B
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK11 mitogen-activated protein kinase 11
MAPK12 mitogen-activated protein kinase 12
MAPK13 mitogen-activated protein kinase 13
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MARCKSL1 MARCKS-like 1
MYD88 myeloid differentiation primary response 88
NANOS2 nanos homolog 2 (Drosophila)
NCF1 neutrophil cytosolic factor 1
NCF2 neutrophil cytosolic factor 2
NCF4 neutrophil cytosolic factor 4, 40kDa
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
PRKCB protein kinase C, beta
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
STAT1 signal transducer and activator of transcription 1, 91kDa
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFB3 transforming growth factor, beta 3
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase