| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lenalidomide (hemihydrate) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lenalidomide (hemihydrate)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.269218 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0922988 |
| HDAC9 | histone deacetylase 9 | 0.0860549 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.078529 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0748313 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0624119 |
| DST | dystonin | 0.0622203 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0573453 |
| MSN | moesin | 0.0561363 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0539498 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0535482 |
| POTEF | POTE ankyrin domain family, member F | 0.0504962 |
| PRELID2 | PRELI domain containing 2 | 0.0495535 |
| EGFR | epidermal growth factor receptor | 0.0473951 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0472104 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0448064 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0447229 |
| VEGFC | vascular endothelial growth factor C | 0.0436052 |
| PKM | pyruvate kinase, muscle | 0.0429601 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0422139 |
| MAP1B | microtubule-associated protein 1B | 0.0415394 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0414703 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0408232 |
| NAV2 | neuron navigator 2 | 0.0400394 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.039528 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0394176 |
| MYADM | myeloid-associated differentiation marker | 0.0376555 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.037061 |
| SEPTIN7 | septin 7 | 0.0363499 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0362053 |
| E2F7 | E2F transcription factor 7 | 0.0358151 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0355829 |
| NAV1 | neuron navigator 1 | 0.0353301 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0351504 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0348406 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0342644 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0333485 |
| CD109 | CD109 molecule | 0.0330106 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0326691 |
| RASAL2 | RAS protein activator like 2 | 0.0326209 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0325635 |
| CENPF | centromere protein F, 350/400kDa | 0.0322292 |
| PCM1 | pericentriolar material 1 | 0.032134 |
| SET | SET nuclear proto-oncogene | 0.0317806 |
| TPM3 | tropomyosin 3 | 0.0312733 |
| AXL | AXL receptor tyrosine kinase | 0.0308158 |
| RND3 | Rho family GTPase 3 | 0.0304035 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0302559 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0301538 |
| BCL2L1 | BCL2-like 1 | 0.029746 |
| ZNF638 | zinc finger protein 638 | 0.0295264 |
| TLE4 | transducin-like enhancer of split 4 | 0.0288066 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0287925 |
| COPA | coatomer protein complex, subunit alpha | 0.0285125 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0283384 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.027915 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0278223 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0275939 |
| CD44 | CD44 molecule (Indian blood group) | 0.0269199 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0265145 |
| ZNF207 | zinc finger protein 207 | 0.026446 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0263239 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0259854 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0258558 |
| BTBD10 | BTB (POZ) domain containing 10 | 0.0257462 |
| ASPH | aspartate beta-hydroxylase | 0.0257298 |
| DSPP | dentin sialophosphoprotein | 0.0257023 |
| ZNF148 | zinc finger protein 148 | 0.0256891 |
| GOLGA4 | golgin A4 | 0.0255203 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0251442 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0247768 |
| DCLK2 | doublecortin-like kinase 2 | 0.0245977 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0245746 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0245504 |
| RB1 | retinoblastoma 1 | 0.0245352 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0240275 |
| PCBP2 | poly(rC) binding protein 2 | 0.0239134 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | 0.0238588 |
| NEK7 | NIMA-related kinase 7 | 0.0233962 |
| L1CAM | L1 cell adhesion molecule | 0.0233668 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0233236 |
| DIAPH3 | diaphanous-related formin 3 | 0.0233104 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0232721 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0230917 |
| MCL1 | myeloid cell leukemia 1 | 0.0229715 |
| YEATS2 | YEATS domain containing 2 | 0.0227429 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0226371 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0225966 |
| MED13 | mediator complex subunit 13 | 0.0225632 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0225136 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0223491 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.0223136 |
| ERBIN | erbb2 interacting protein | 0.0219842 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0217109 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0216247 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0215891 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0214956 |
| SERTAD2 | SERTA domain containing 2 | 0.021477 |
| CUL4A | cullin 4A | 0.0213698 |
| TGFB1 | transforming growth factor, beta 1 | 0.0213111 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.189072 |
| THBS2 | thrombospondin 2 | -0.146648 |
| LOX | lysyl oxidase | -0.144412 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.123297 |
| TMSB10 | thymosin beta 10 | -0.119607 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.111333 |
| AHNAK | AHNAK nucleoprotein | -0.109604 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.106057 |
| COL3A1 | collagen, type III, alpha 1 | -0.105948 |
| MT2A | metallothionein 2A | -0.0915199 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0788095 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0765649 |
| FBN1 | fibrillin 1 | -0.0750506 |
| COL1A2 | collagen, type I, alpha 2 | -0.0746698 |
| PTMA | prothymosin, alpha | -0.0738178 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0650199 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0644513 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0609897 |
| HLA-B | major histocompatibility complex, class I, B | -0.0587143 |
| CAVIN1 | caveolae associated protein 1 | -0.0585415 |
| LOXL2 | lysyl oxidase-like 2 | -0.0574903 |
| ANXA2 | annexin A2 | -0.054656 |
| AUTS2 | autism susceptibility candidate 2 | -0.0542481 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0515849 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0515537 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0505391 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0503757 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0494867 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0469396 |
| S100A10 | S100 calcium binding protein A10 | -0.0453289 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0449949 |
| COL5A2 | collagen, type V, alpha 2 | -0.0446382 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0441283 |
| PODXL | podocalyxin-like | -0.0426211 |
| HLA-C | major histocompatibility complex, class I, C | -0.0417802 |
| STC1 | stanniocalcin 1 | -0.0395161 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0384129 |
| ZNF217 | zinc finger protein 217 | -0.0383382 |
| HLA-E | major histocompatibility complex, class I, E | -0.0380011 |
| NDRG1 | N-myc downstream regulated 1 | -0.0372469 |
| APP | amyloid beta (A4) precursor protein | -0.0358935 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0355642 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0354267 |
| RPS24 | ribosomal protein S24 | -0.035315 |
| UBC | ubiquitin C | -0.0350208 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0349107 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0345208 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0334991 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0329547 |
| FRMD4A | FERM domain containing 4A | -0.0321597 |
| HDLBP | high density lipoprotein binding protein | -0.0315699 |
| INSIG1 | insulin induced gene 1 | -0.0302828 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0301069 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0296866 |
| RPL35A | ribosomal protein L35a | -0.0296758 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0294752 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0289808 |
| CALR | calreticulin | -0.028921 |
| ADAR | adenosine deaminase, RNA-specific | -0.0287697 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0287008 |
| IER3 | immediate early response 3 | -0.0284938 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0276397 |
| FTL | ferritin, light polypeptide | -0.027588 |
| CANX | calnexin | -0.0272912 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0272605 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0272132 |
| COL5A1 | collagen, type V, alpha 1 | -0.0263483 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0262231 |
| RPL34 | ribosomal protein L34 | -0.0261944 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0261451 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.02608 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0256279 |
| GPC6 | glypican 6 | -0.0255028 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0254275 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0249286 |
| WTAP | Wilms tumor 1 associated protein | -0.0247525 |
| TMSB4X | thymosin beta 4, X-linked | -0.024397 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0242269 |
| KLF6 | Kruppel-like factor 6 | -0.0240794 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0240387 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0238411 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0237096 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0237002 |
| RPL23 | ribosomal protein L23 | -0.0236875 |
| MEIS2 | Meis homeobox 2 | -0.0233735 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0232116 |
| GNAS | GNAS complex locus | -0.0232002 |
| RPL32 | ribosomal protein L32 | -0.0230478 |
| RIGI | RNA sensor RIG-I | -0.0224514 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0224314 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0223743 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0223073 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0222022 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0221185 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0218829 |
| SBF2 | SET binding factor 2 | -0.0218096 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.021799 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0216685 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0216076 |
| RPS15 | ribosomal protein S15 | -0.0213948 |
