| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lenalidomide (hemihydrate) perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lenalidomide (hemihydrate)_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.100269 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0996471 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0966813 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0943476 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0809595 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0688484 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0680055 |
| ITGAV | integrin, alpha V | 0.0523528 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0516056 |
| B2M | beta-2-microglobulin | 0.0513924 |
| TRAM1 | translocation associated membrane protein 1 | 0.0498823 |
| NRP2 | neuropilin 2 | 0.0494596 |
| RTN4 | reticulon 4 | 0.0490486 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0466789 |
| GPC5 | glypican 5 | 0.0459477 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0456563 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0451899 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0451477 |
| ARRDC3 | arrestin domain containing 3 | 0.0442932 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0421875 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0418143 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.041524 |
| JAK1 | Janus kinase 1 | 0.0404883 |
| EFHD2 | EF-hand domain family, member D2 | 0.0399738 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0391936 |
| NRP1 | neuropilin 1 | 0.0390209 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0387981 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0387538 |
| TKT | transketolase | 0.0386471 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0372748 |
| LDHA | lactate dehydrogenase A | 0.0371957 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0371067 |
| IRS2 | insulin receptor substrate 2 | 0.0367225 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0367126 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0354038 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0348952 |
| CD44 | CD44 molecule (Indian blood group) | 0.0348314 |
| CENPF | centromere protein F, 350/400kDa | 0.0339117 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0335161 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0332452 |
| SMAD3 | SMAD family member 3 | 0.0327096 |
| CBX3 | chromobox homolog 3 | 0.0326188 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0323438 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 0.0320806 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0320483 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0316984 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0316757 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0316456 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.031278 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0311082 |
| NFIB | nuclear factor I/B | 0.0310414 |
| PCBP2 | poly(rC) binding protein 2 | 0.0303925 |
| PCMTD1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 | 0.0303199 |
| MYOF | myoferlin | 0.0302877 |
| SET | SET nuclear proto-oncogene | 0.0302695 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0302299 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0300227 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0294689 |
| WASL | Wiskott-Aldrich syndrome-like | 0.0294475 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0294068 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0293961 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0293265 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0288866 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0286146 |
| METTL15 | methyltransferase like 15 | 0.0285856 |
| NAV2 | neuron navigator 2 | 0.0285315 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0285147 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0284228 |
| RPS4X | ribosomal protein S4, X-linked | 0.0283207 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0281265 |
| EXOC6B | exocyst complex component 6B | 0.0280949 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0280229 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0279805 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0278257 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.027761 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0275605 |
| ENAH | enabled homolog (Drosophila) | 0.0275082 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0272864 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0272584 |
| SEPTIN9 | septin 9 | 0.0272328 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0269038 |
| RPS20 | ribosomal protein S20 | 0.026899 |
| CAND1 | cullin-associated and neddylation-dissociated 1 | 0.0266783 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0266588 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0266315 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0266047 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0264066 |
| RPL7 | ribosomal protein L7 | 0.0263327 |
| RPLP0 | ribosomal protein, large, P0 | 0.0263105 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0259154 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.025782 |
| UBC | ubiquitin C | 0.0257773 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0255971 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0255519 |
| TMEM106B | transmembrane protein 106B | 0.0252717 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0252309 |
| TES | testin LIM domain protein | 0.0250753 |
| RPS6 | ribosomal protein S6 | 0.0250295 |
| TPR | translocated promoter region, nuclear basket protein | 0.0246877 |
| TUSC3 | tumor suppressor candidate 3 | 0.024686 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FRMD4A | FERM domain containing 4A | -0.312264 |
| GPC6 | glypican 6 | -0.146093 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.143806 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0956381 |
| CP | ceruloplasmin (ferroxidase) | -0.0904809 |
| ASPH | aspartate beta-hydroxylase | -0.089364 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0831545 |
| TMSB10 | thymosin beta 10 | -0.0806317 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0753859 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0702299 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0645721 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0583541 |
| CUX1 | cut-like homeobox 1 | -0.0574105 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0563302 |
| CALR | calreticulin | -0.0543568 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0518988 |
| VIM | vimentin | -0.0500169 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0496219 |
| FAM107B | family with sequence similarity 107, member B | -0.0484566 |
| FN1 | fibronectin 1 | -0.0479118 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0476498 |
| POTEF | POTE ankyrin domain family, member F | -0.0469816 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0466504 |
| CMIP | c-Maf inducing protein | -0.0460808 |
| RPL35A | ribosomal protein L35a | -0.0455599 |
| COL5A1 | collagen, type V, alpha 1 | -0.0453448 |
| CTSD | cathepsin D | -0.0440326 |
| DGKI | diacylglycerol kinase, iota | -0.0420814 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0412232 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0407362 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0407175 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0401009 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.039637 |
| RAI14 | retinoic acid induced 14 | -0.0395533 |
| SORCS2 | sortilin-related VPS10 domain containing receptor 2 | -0.0392452 |
| HM13 | histocompatibility (minor) 13 | -0.0391755 |
| TNS3 | tensin 3 | -0.0390042 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.038434 |
| PTMA | prothymosin, alpha | -0.0382411 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0380533 |
| RRBP1 | ribosome binding protein 1 | -0.0374806 |
| GLIS3 | GLIS family zinc finger 3 | -0.0364943 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0362924 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0359025 |
| RPS24 | ribosomal protein S24 | -0.0358266 |
| HLA-B | major histocompatibility complex, class I, B | -0.0353518 |
| NDRG1 | N-myc downstream regulated 1 | -0.0351281 |
| HDLBP | high density lipoprotein binding protein | -0.0345927 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0345617 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0343523 |
| TPM1 | tropomyosin 1 (alpha) | -0.0342297 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0336582 |
| CADM1 | cell adhesion molecule 1 | -0.0330095 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0327708 |
| TPM4 | tropomyosin 4 | -0.0314547 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0313889 |
| BNC2 | basonuclin 2 | -0.0310744 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0310532 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0309138 |
| PLEC | plectin | -0.0306448 |
| NAV1 | neuron navigator 1 | -0.0303038 |
| ANXA4 | annexin A4 | -0.0298101 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0296676 |
| MAP1B | microtubule-associated protein 1B | -0.0291185 |
| FAM20C | family with sequence similarity 20, member C | -0.029066 |
| FLNA | filamin A, alpha | -0.0290471 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0288654 |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 | -0.028632 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0285853 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0284865 |
| STK17A | serine/threonine kinase 17a | -0.0284665 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0283397 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | -0.0279427 |
| FRMD5 | FERM domain containing 5 | -0.0278674 |
| PALLD | palladin, cytoskeletal associated protein | -0.0277112 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0276237 |
| VCL | vinculin | -0.0275145 |
| PMM2 | phosphomannomutase 2 | -0.027051 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0268084 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.0267986 |
| AHNAK | AHNAK nucleoprotein | -0.0267163 |
| RPL34 | ribosomal protein L34 | -0.0261288 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0260183 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | -0.0257127 |
| SEC24D | SEC24 family member D | -0.0257106 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0255535 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0255154 |
| RPL31 | ribosomal protein L31 | -0.0249619 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0248546 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0247759 |
| PTH2R | parathyroid hormone 2 receptor | -0.0246329 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0244285 |
| MMP7 | matrix metallopeptidase 7 | -0.024346 |
| PAX8 | paired box 8 | -0.0242503 |
| ACTG1 | actin gamma 1 | -0.0242023 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0241876 |
| TMEM263 | transmembrane protein 263 | -0.0241765 |
| CDC37 | cell division cycle 37 | -0.0241507 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0240027 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0238752 |
