| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lenalidomide (hemihydrate) perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lenalidomide (hemihydrate)_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.166672 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.152607 |
| RPS6 | ribosomal protein S6 | 0.0987113 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0917603 |
| VIM | vimentin | 0.085271 |
| RPLP1 | ribosomal protein, large, P1 | 0.0786749 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0758024 |
| ACTG1 | actin gamma 1 | 0.0702153 |
| STC1 | stanniocalcin 1 | 0.0581224 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0577551 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0570364 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0540214 |
| SLC38A2 | solute carrier family 38, member 2 | 0.053293 |
| DUSP5 | dual specificity phosphatase 5 | 0.052891 |
| MCL1 | myeloid cell leukemia 1 | 0.0525152 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0506263 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0496914 |
| ST6GAL2 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 | 0.0486891 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.048665 |
| SMYD3 | SET and MYND domain containing 3 | 0.0482244 |
| PCBP2 | poly(rC) binding protein 2 | 0.0469852 |
| RPS19 | ribosomal protein S19 | 0.0447727 |
| RPL35A | ribosomal protein L35a | 0.0440684 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0440215 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0438122 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0418352 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0417301 |
| FLNB | filamin B, beta | 0.0416619 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0414551 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0413172 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0406899 |
| RPL23 | ribosomal protein L23 | 0.0402692 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0402319 |
| BMP6 | bone morphogenetic protein 6 | 0.0394684 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0390604 |
| MED13 | mediator complex subunit 13 | 0.038878 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0384097 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0374071 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0373572 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0361795 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0358051 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.035283 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0352149 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.0343008 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0339825 |
| INTS6 | integrator complex subunit 6 | 0.0331752 |
| RPS20 | ribosomal protein S20 | 0.0318072 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0308162 |
| USP47 | ubiquitin specific peptidase 47 | 0.0303913 |
| MYO1E | myosin IE | 0.0302512 |
| BPTF | bromodomain PHD finger transcription factor | 0.0301931 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0296986 |
| HMGA2 | high mobility group AT-hook 2 | 0.0296336 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.029542 |
| ERBIN | erbb2 interacting protein | 0.0293483 |
| DUSP16 | dual specificity phosphatase 16 | 0.0291627 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0289514 |
| PAQR5 | progestin and adipoQ receptor family member V | 0.0286098 |
| TOP1 | topoisomerase (DNA) I | 0.0283949 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0283378 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0282163 |
| ZNF638 | zinc finger protein 638 | 0.0281801 |
| ETNK1 | ethanolamine kinase 1 | 0.02802 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0278498 |
| WWOX | WW domain containing oxidoreductase | 0.0277559 |
| MAP7 | microtubule-associated protein 7 | 0.0265078 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.026425 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0260993 |
| KLF6 | Kruppel-like factor 6 | 0.0258549 |
| ATP13A3 | ATPase type 13A3 | 0.0254275 |
| PDE10A | phosphodiesterase 10A | 0.0253623 |
| RND3 | Rho family GTPase 3 | 0.0253153 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0249903 |
| RPLP0 | ribosomal protein, large, P0 | 0.0248532 |
| AXL | AXL receptor tyrosine kinase | 0.0245436 |
| RPL37A | ribosomal protein L37a | 0.0241756 |
| GRAMD1B | GRAM domain containing 1B | 0.0239012 |
| AADAC | arylacetamide deacetylase | 0.0238338 |
| NABP1 | nucleic acid binding protein 1 | 0.0236606 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0235307 |
| SSH1 | slingshot protein phosphatase 1 | 0.0233558 |
| LMO7 | LIM domain 7 | 0.0231621 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0229551 |
| MED13L | mediator complex subunit 13-like | 0.0228803 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0228031 |
| EGR1 | early growth response 1 | 0.0226045 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.0225017 |
| RSPO3 | R-spondin 3 | 0.0222584 |
| ITGB5 | integrin, beta 5 | 0.0222507 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | 0.0221126 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0219641 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.021897 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0216403 |
| MYO10 | myosin X | 0.0215983 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0215053 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0214081 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0212949 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0212727 |
| TMEM156 | transmembrane protein 156 | 0.0210255 |
| CCDC88A | coiled-coil domain containing 88A | 0.0208837 |
| Symbol | Name | Standardized Value |
|---|---|---|
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.133806 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.126524 |
| TXNRD1 | thioredoxin reductase 1 | -0.117699 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.116395 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0912832 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0901155 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0866949 |
| RNF213 | ring finger protein 213 | -0.0786621 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0752766 |
| LDHA | lactate dehydrogenase A | -0.0750536 |
| NDRG1 | N-myc downstream regulated 1 | -0.0740654 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0723796 |
| VMP1 | vacuole membrane protein 1 | -0.072134 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0713268 |
| TNS3 | tensin 3 | -0.0682043 |
| SBF2 | SET binding factor 2 | -0.0639484 |
| CLTC | clathrin, heavy chain (Hc) | -0.0629174 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0602982 |
| GLIS3 | GLIS family zinc finger 3 | -0.0585191 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0557289 |
| EHBP1 | EH domain binding protein 1 | -0.0554709 |
| CANX | calnexin | -0.054712 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.0527238 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.051793 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0513231 |
| OSMR | oncostatin M receptor | -0.051278 |
| CA12 | carbonic anhydrase XII | -0.0510312 |
| MAP1B | microtubule-associated protein 1B | -0.0494161 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0487336 |
| CMIP | c-Maf inducing protein | -0.0484979 |
| RPS2 | ribosomal protein S2 | -0.0482547 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.04781 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0475651 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0466806 |
| FAM107B | family with sequence similarity 107, member B | -0.0460884 |
| AOPEP | aminopeptidase O (putative) | -0.0450895 |
| RIGI | RNA sensor RIG-I | -0.0418372 |
| CLINT1 | clathrin interactor 1 | -0.0411288 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0409387 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0405385 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0401216 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0394191 |
| ASPH | aspartate beta-hydroxylase | -0.0394003 |
| CENPF | centromere protein F, 350/400kDa | -0.0393583 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0391302 |
| TCF12 | transcription factor 12 | -0.0378388 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0371446 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0367023 |
| HDLBP | high density lipoprotein binding protein | -0.0366263 |
| DSTN | destrin (actin depolymerizing factor) | -0.0364907 |
| ADAR | adenosine deaminase, RNA-specific | -0.0362805 |
| ATG7 | autophagy related 7 | -0.0361229 |
| MKI67 | marker of proliferation Ki-67 | -0.035757 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0357454 |
| ANLN | anillin, actin binding protein | -0.0357355 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0357112 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0356178 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.035175 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0348725 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0348519 |
| KRT18 | keratin 18, type I | -0.0347026 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0346044 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0339322 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0338663 |
| MYOF | myoferlin | -0.033655 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0335528 |
| RRBP1 | ribosome binding protein 1 | -0.0335359 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0333857 |
| GOLGB1 | golgin B1 | -0.0331813 |
| ANXA4 | annexin A4 | -0.0331618 |
| LAMB3 | laminin, beta 3 | -0.0330153 |
| TMSB10 | thymosin beta 10 | -0.0329845 |
| RAI14 | retinoic acid induced 14 | -0.0328327 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0327589 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0324525 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0322448 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.0321521 |
| GPC6 | glypican 6 | -0.0321326 |
| KRT7 | keratin 7, type II | -0.0316404 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0309865 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0308075 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0303424 |
| NRP1 | neuropilin 1 | -0.0302969 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0300832 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0296037 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.029579 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0293064 |
| PGK1 | phosphoglycerate kinase 1 | -0.0292383 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.0288605 |
| LMNA | lamin A/C | -0.028833 |
| ENO1 | enolase 1, (alpha) | -0.0287827 |
| EREG | epiregulin | -0.0287362 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0286482 |
| PLEC | plectin | -0.0281998 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0280607 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | -0.0279681 |
| APP | amyloid beta (A4) precursor protein | -0.0278936 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | -0.0277769 |
| TPM1 | tropomyosin 1 (alpha) | -0.0276654 |
| TMSB4X | thymosin beta 4, X-linked | -0.0276465 |
