| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lenalidomide (hemihydrate) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lenalidomide (hemihydrate)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.140665 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.13371 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | 0.125266 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.119534 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | 0.0914596 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0874191 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0871881 |
| FMNL2 | formin-like 2 | 0.0674758 |
| SACK1A | scaffolding CK1 anchoring protein A | 0.0673535 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0644899 |
| CLMP | CXADR-like membrane protein | 0.0641286 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0584814 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0570539 |
| PLEK2 | pleckstrin 2 | 0.0536273 |
| UPP1 | uridine phosphorylase 1 | 0.0516979 |
| LAMB3 | laminin, beta 3 | 0.0502557 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0496809 |
| BMP6 | bone morphogenetic protein 6 | 0.0487576 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0478165 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0453664 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0450684 |
| TMCC3 | transmembrane and coiled-coil domain family 3 | 0.0441844 |
| FTL | ferritin, light polypeptide | 0.0431694 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.0416825 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0409548 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.040652 |
| CDCP1 | CUB domain containing protein 1 | 0.0403143 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0380591 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0361221 |
| TPM4 | tropomyosin 4 | 0.0357885 |
| AK1 | adenylate kinase 1 | 0.0350121 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0349979 |
| MCL1 | myeloid cell leukemia 1 | 0.0345924 |
| MSN | moesin | 0.0339315 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0329435 |
| MXD1 | MAX dimerization protein 1 | 0.0329224 |
| PMM2 | phosphomannomutase 2 | 0.032729 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0323175 |
| TRRAP | transformation/transcription domain-associated protein | 0.0322056 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0317309 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0315788 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0314746 |
| SNX9 | sorting nexin 9 | 0.0313496 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0312129 |
| RUNX1 | runt-related transcription factor 1 | 0.0310239 |
| TXNRD1 | thioredoxin reductase 1 | 0.0309922 |
| MYO9B | myosin IXB | 0.0309186 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0308955 |
| EFNA5 | ephrin-A5 | 0.0304069 |
| EVI5 | ecotropic viral integration site 5 | 0.0300505 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0294163 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0292884 |
| NXN | nucleoredoxin | 0.0286424 |
| KLK10 | kallikrein-related peptidase 10 | 0.0283075 |
| SEC24A | SEC24 family member A | 0.0277824 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0275853 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.027008 |
| ATP13A3 | ATPase type 13A3 | 0.0267984 |
| MMP1 | matrix metallopeptidase 1 | 0.0261698 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.025817 |
| PARD3 | par-3 family cell polarity regulator | 0.0254866 |
| B2M | beta-2-microglobulin | 0.0252385 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0252072 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0251468 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.0246765 |
| MACO1 | macoilin 1 | 0.0246304 |
| ABHD3 | abhydrolase domain containing 3 | 0.0245934 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0244738 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0242463 |
| STC1 | stanniocalcin 1 | 0.0239953 |
| SMNDC1 | survival motor neuron domain containing 1 | 0.0238983 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.023862 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.023765 |
| SEPTIN10 | septin 10 | 0.0232953 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0229983 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0229713 |
| TOR1AIP2 | torsin A interacting protein 2 | 0.0228086 |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) | 0.0227945 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0226148 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.022513 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | 0.0224994 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0224965 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0221886 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0220915 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.0217861 |
| CNST | consortin, connexin sorting protein | 0.0216924 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.021609 |
| TGFA | transforming growth factor, alpha | 0.0214256 |
| SETX | senataxin | 0.0213662 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0213635 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0213406 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0212368 |
| USP34 | ubiquitin specific peptidase 34 | 0.0212351 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0211307 |
| OXSR1 | oxidative stress responsive 1 | 0.0211186 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0210634 |
| UBAP2 | ubiquitin associated protein 2 | 0.0210333 |
| PARD6B | par-6 family cell polarity regulator beta | 0.0207566 |
| FBXO11 | F-box protein 11 | 0.0207227 |
| TMEM165 | transmembrane protein 165 | 0.0206881 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.115694 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.110547 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.109089 |
| MUC17 | mucin 17, cell surface associated | -0.101847 |
| VCAN | versican | -0.100023 |
| LMO7 | LIM domain 7 | -0.098341 |
| PTMA | prothymosin, alpha | -0.0965522 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0928764 |
| S100A10 | S100 calcium binding protein A10 | -0.0922431 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0872785 |
| EZR | ezrin | -0.0827035 |
| POTEF | POTE ankyrin domain family, member F | -0.0812204 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0763345 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0740454 |
| VIM | vimentin | -0.0728892 |
| MYOF | myoferlin | -0.0700329 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0699318 |
| ANXA2 | annexin A2 | -0.063943 |
| ITGA6 | integrin, alpha 6 | -0.0620928 |
| EMP1 | epithelial membrane protein 1 | -0.0615829 |
| SQSTM1 | sequestosome 1 | -0.0613182 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0611712 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.060815 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0603824 |
| ASPH | aspartate beta-hydroxylase | -0.0586829 |
| ACTG1 | actin gamma 1 | -0.0580327 |
| HMGA1 | high mobility group AT-hook 1 | -0.057791 |
| KRT8 | keratin 8, type II | -0.0573319 |
| AHNAK | AHNAK nucleoprotein | -0.0562918 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0551637 |
| ITGB4 | integrin, beta 4 | -0.054203 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0535605 |
| DSG2 | desmoglein 2 | -0.0529634 |
| LAMA4 | laminin, alpha 4 | -0.0522062 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0517566 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0511935 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0510879 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0508641 |
| PLEC | plectin | -0.050433 |
| S100A4 | S100 calcium binding protein A4 | -0.0503548 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | -0.0501519 |
| KLF6 | Kruppel-like factor 6 | -0.0494938 |
| COL17A1 | collagen, type XVII, alpha 1 | -0.0477822 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0468265 |
| PERP | PERP, TP53 apoptosis effector | -0.0448776 |
| KRT18 | keratin 18, type I | -0.0445388 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.044064 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.043885 |
| CD2AP | CD2-associated protein | -0.0433897 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0424825 |
| LDHA | lactate dehydrogenase A | -0.042332 |
| KRT19 | keratin 19, type I | -0.0410995 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0405739 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0404904 |
| SDC4 | syndecan 4 | -0.0399125 |
| WASF2 | WAS protein family, member 2 | -0.0391022 |
| ANLN | anillin, actin binding protein | -0.0384729 |
| FAT1 | FAT atypical cadherin 1 | -0.0381335 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.038129 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0380679 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0374808 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0373263 |
| RBM39 | RNA binding motif protein 39 | -0.0372748 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0372133 |
| PRELID2 | PRELI domain containing 2 | -0.0371171 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0361281 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0359935 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0357456 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | -0.0354302 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0349809 |
| SMAD3 | SMAD family member 3 | -0.034955 |
| NPSR1 | neuropeptide S receptor 1 | -0.0348526 |
| TOP1 | topoisomerase (DNA) I | -0.0348099 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0343917 |
| FAM107B | family with sequence similarity 107, member B | -0.033526 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.03336 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0333425 |
| MYO6 | myosin VI | -0.0322593 |
| ANXA11 | annexin A11 | -0.0316398 |
| EPCAM | epithelial cell adhesion molecule | -0.0314859 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0311839 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0311736 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0311705 |
| TUFT1 | tuftelin 1 | -0.0311587 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0311537 |
| SULF2 | sulfatase 2 | -0.0307865 |
| DST | dystonin | -0.0307087 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0303983 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0303393 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0295211 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0293487 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0291055 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | -0.0289797 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.028925 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0286269 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0283423 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0282683 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | -0.0277039 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0274973 |
| ZNF292 | zinc finger protein 292 | -0.0273667 |
