| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lenalidomide (hemihydrate) perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lenalidomide (hemihydrate)_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF608 | zinc finger protein 608 | 0.139402 |
| COL5A2 | collagen, type V, alpha 2 | 0.124062 |
| JMJD1C | jumonji domain containing 1C | 0.120969 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.116138 |
| VCL | vinculin | 0.106691 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0985344 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0947358 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | 0.0742884 |
| UBAP2 | ubiquitin associated protein 2 | 0.0716361 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0656803 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0631725 |
| MED13 | mediator complex subunit 13 | 0.0598559 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0586641 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0573744 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0571836 |
| PCNX4 | pecanex 4 | 0.0571736 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0553341 |
| WLS | wntless Wnt ligand secretion mediator | 0.0533031 |
| PCBP2 | poly(rC) binding protein 2 | 0.0511171 |
| SERTAD2 | SERTA domain containing 2 | 0.0505885 |
| SIK3 | SIK family kinase 3 | 0.0499162 |
| CENPF | centromere protein F, 350/400kDa | 0.0477777 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0451346 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0437168 |
| DST | dystonin | 0.0421094 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0410007 |
| TAOK1 | TAO kinase 1 | 0.0407109 |
| VEGFC | vascular endothelial growth factor C | 0.0402846 |
| FERMT2 | fermitin family member 2 | 0.0394056 |
| MKI67 | marker of proliferation Ki-67 | 0.0391296 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0390818 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0388741 |
| ZNF207 | zinc finger protein 207 | 0.0388706 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0385109 |
| NBEAL1 | neurobeachin-like 1 | 0.0383524 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0377267 |
| PPP4R2 | protein phosphatase 4, regulatory subunit 2 | 0.0377152 |
| NRDC | nardilysin convertase | 0.0372473 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0369239 |
| ARFGEF3 | ARFGEF family member 3 | 0.036351 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited | 0.0359258 |
| NFIB | nuclear factor I/B | 0.0359234 |
| INTS6 | integrator complex subunit 6 | 0.0351441 |
| SIK2 | salt-inducible kinase 2 | 0.0345658 |
| RPLP1 | ribosomal protein, large, P1 | 0.0345071 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0338738 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.032905 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0328993 |
| ZNF148 | zinc finger protein 148 | 0.0328356 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0319982 |
| VMP1 | vacuole membrane protein 1 | 0.0316504 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0315338 |
| NFIA | nuclear factor I/A | 0.0314657 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0311869 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0309496 |
| TBL1X | transducin (beta)-like 1X-linked | 0.0308363 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0306279 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0305989 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0302826 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0302793 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.029806 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0297879 |
| ZNF644 | zinc finger protein 644 | 0.0297591 |
| SMAD6 | SMAD family member 6 | 0.0297588 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0297322 |
| AFDN | afadin, adherens junction formation factor | 0.0296185 |
| PCM1 | pericentriolar material 1 | 0.0295464 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.0295101 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0292874 |
| GPATCH8 | G patch domain containing 8 | 0.0291984 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0291424 |
| CEP350 | centrosomal protein 350kDa | 0.0291097 |
| NEBL | nebulette | 0.0288603 |
| SETD5 | SET domain containing 5 | 0.0288142 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0287919 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0285799 |
| TBCA | tubulin folding cofactor A | 0.0285617 |
| CARD18 | caspase recruitment domain family, member 18 | 0.0284707 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.028259 |
| GNAS | GNAS complex locus | 0.0281455 |
| NEK1 | NIMA-related kinase 1 | 0.0280599 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0279007 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0278848 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0277601 |
| RCOR1 | REST corepressor 1 | 0.0275725 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0273746 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0273501 |
| PBRM1 | polybromo 1 | 0.0272732 |
| CPLANE1 | ciliogenesis and planar polarity effector complex subunit 1 | 0.027253 |
| KIAA1328 | KIAA1328 | 0.0271542 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0271163 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0271103 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0269934 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.026945 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0268549 |
| KLC1 | kinesin light chain 1 | 0.0267888 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.026675 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0266499 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0262728 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) | 0.0262543 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.126174 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0814069 |
| FMNL2 | formin-like 2 | -0.0708323 |
| SHROOM3 | shroom family member 3 | -0.0661787 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0654467 |
| RAD51B | RAD51 paralog B | -0.0650579 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0568982 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0539015 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0537297 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0504279 |
| ATP11A | ATPase, class VI, type 11A | -0.0484396 |
| LDHA | lactate dehydrogenase A | -0.042562 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -0.0399533 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0398857 |
| TENM3 | teneurin transmembrane protein 3 | -0.0392003 |
| SMYD3 | SET and MYND domain containing 3 | -0.0388806 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0360206 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0352123 |
| RCC1 | regulator of chromosome condensation 1 | -0.0351293 |
| NRG1 | neuregulin 1 | -0.0344825 |
| ITSN1 | intersectin 1 (SH3 domain protein) | -0.0343843 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | -0.0342215 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -0.0330999 |
| WDR70 | WD repeat domain 70 | -0.0309063 |
| IGF2 | insulin-like growth factor 2 | -0.03082 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0300812 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0297589 |
| SCAI | suppressor of cancer cell invasion | -0.0289282 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0288377 |
| RPL31 | ribosomal protein L31 | -0.0282802 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.028265 |
| LDLRAD3 | low density lipoprotein receptor class A domain containing 3 | -0.0271105 |
| KIAA1671 | KIAA1671 | -0.0265287 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0257751 |
| PRICKLE1 | prickle homolog 1 (Drosophila) | -0.0256701 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.025662 |
| CALU | calumenin | -0.025477 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0253886 |
| MDN1 | MDN1, midasin homolog (yeast) | -0.0246012 |
| RBM25 | RNA binding motif protein 25 | -0.0244362 |
| RPL7A | ribosomal protein L7a | -0.0244348 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.023956 |
| RBM28 | RNA binding motif protein 28 | -0.0239267 |
| SEC63 | SEC63 homolog (S. cerevisiae) | -0.0234985 |
| TMEM178B | transmembrane protein 178B | -0.0234875 |
| FTL | ferritin, light polypeptide | -0.0234215 |
| TNRC6B | trinucleotide repeat containing 6B | -0.022814 |
| RPS24 | ribosomal protein S24 | -0.0226178 |
| TOM1L2 | target of myb1-like 2 (chicken) | -0.0225522 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0222681 |
| RPS27A | ribosomal protein S27a | -0.0220428 |
| CDC37 | cell division cycle 37 | -0.0217836 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0212348 |
| B2M | beta-2-microglobulin | -0.0211257 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0211205 |
| SRPK1 | SRSF protein kinase 1 | -0.0211126 |
| PARD3 | par-3 family cell polarity regulator | -0.0208249 |
| USP25 | ubiquitin specific peptidase 25 | -0.0207456 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0206741 |
| DIAPH2 | diaphanous-related formin 2 | -0.0204723 |
| PEG10 | paternally expressed 10 | -0.0203857 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0203793 |
| TENM2 | teneurin transmembrane protein 2 | -0.0202965 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.020164 |
| ARF1 | ADP-ribosylation factor 1 | -0.0197204 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0197093 |
| KIAA1958 | KIAA1958 | -0.0196423 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0195982 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0195043 |
| RPS15 | ribosomal protein S15 | -0.0192293 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0192028 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0190795 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0190773 |
| SMAD3 | SMAD family member 3 | -0.0190602 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | -0.0190527 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase | -0.0190273 |
| APTX | aprataxin | -0.0189962 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0188923 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0188765 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0188702 |
| EPN2 | epsin 2 | -0.0188353 |
| RPS29 | ribosomal protein S29 | -0.0186535 |
| TRAP1 | TNF receptor-associated protein 1 | -0.018484 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0183095 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | -0.0181881 |
| RPL23 | ribosomal protein L23 | -0.0180894 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0179872 |
| SCG2 | secretogranin II | -0.0179177 |
| RPL13A | ribosomal protein L13a | -0.0178299 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0177278 |
| TMEM117 | transmembrane protein 117 | -0.017676 |
| WDFY3 | WD repeat and FYVE domain containing 3 | -0.017542 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | -0.0175272 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0175207 |
| LONP2 | lon peptidase 2, peroxisomal | -0.0174065 |
| ZNF589 | zinc finger protein 589 | -0.0173904 |
| BSG | basigin (Ok blood group) | -0.0173373 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0173235 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.0172983 |
| NELL2 | NEL-like 2 (chicken) | -0.0172844 |
