| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lenalidomide (hemihydrate) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lenalidomide (hemihydrate)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0801175 |
| MEIS2 | Meis homeobox 2 | 0.0798247 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.061407 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.060807 |
| TLE4 | transducin-like enhancer of split 4 | 0.0585148 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0542209 |
| SIK2 | salt-inducible kinase 2 | 0.0539271 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.052144 |
| RPS6 | ribosomal protein S6 | 0.051652 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0509603 |
| KLHL13 | kelch-like family member 13 | 0.0503956 |
| PLPP1 | phospholipid phosphatase 1 | 0.0501424 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0496164 |
| PCBP2 | poly(rC) binding protein 2 | 0.0477774 |
| GLCCI1 | glucocorticoid induced 1 | 0.046411 |
| RNF213 | ring finger protein 213 | 0.0458864 |
| VCL | vinculin | 0.045837 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0453653 |
| RAD51B | RAD51 paralog B | 0.0446546 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0435907 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0429772 |
| RIGI | RNA sensor RIG-I | 0.0426561 |
| ZFHX3 | zinc finger homeobox 3 | 0.0422093 |
| RPL31 | ribosomal protein L31 | 0.0407081 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0402743 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0398769 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0398554 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0381341 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0379601 |
| FHIT | fragile histidine triad | 0.0378944 |
| ANTXR1 | anthrax toxin receptor 1 | 0.037615 |
| MX2 | MX dynamin-like GTPase 2 | 0.0375274 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0367131 |
| RET | ret proto-oncogene | 0.0364005 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0363013 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0362219 |
| SMYD3 | SET and MYND domain containing 3 | 0.0356686 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0355784 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0349115 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.0346363 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0344436 |
| RPLP1 | ribosomal protein, large, P1 | 0.0337153 |
| CADM2 | cell adhesion molecule 2 | 0.0337096 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0336603 |
| ANGPT1 | angiopoietin 1 | 0.033441 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.033095 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0319538 |
| GREM2 | gremlin 2, DAN family BMP antagonist | 0.0317309 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0316867 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0315794 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.0308663 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0303362 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0302933 |
| RPL34 | ribosomal protein L34 | 0.0300428 |
| PTEN | phosphatase and tensin homolog | 0.0299155 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0298579 |
| TBX2 | T-box 2 | 0.029732 |
| SDC2 | syndecan 2 | 0.0294789 |
| RPL23 | ribosomal protein L23 | 0.0294289 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0290918 |
| RPL27 | ribosomal protein L27 | 0.0288691 |
| NPAS2 | neuronal PAS domain protein 2 | 0.028752 |
| TNPO1 | transportin 1 | 0.0286449 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0284739 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0284527 |
| RPL37A | ribosomal protein L37a | 0.0284324 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0282233 |
| CALD1 | caldesmon 1 | 0.0281618 |
| PLAGL1 | pleiomorphic adenoma gene-like 1 | 0.0272919 |
| FN1 | fibronectin 1 | 0.0262229 |
| PDE10A | phosphodiesterase 10A | 0.026013 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0257485 |
| GAB2 | GRB2-associated binding protein 2 | 0.0257163 |
| SYT1 | synaptotagmin I | 0.0256347 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | 0.0255549 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0254213 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.025148 |
| B2M | beta-2-microglobulin | 0.0248888 |
| INTS6 | integrator complex subunit 6 | 0.0245599 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0242969 |
| JMJD1C | jumonji domain containing 1C | 0.0242466 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.02415 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0237661 |
| CUL5 | cullin 5 | 0.0235539 |
| RPL7 | ribosomal protein L7 | 0.023477 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0232567 |
| IFI44L | interferon-induced protein 44-like | 0.0231475 |
| S100A9 | S100 calcium binding protein A9 | 0.0231337 |
| AUTS2 | autism susceptibility candidate 2 | 0.0231313 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0230907 |
| PNN | pinin, desmosome associated protein | 0.0229538 |
| VMP1 | vacuole membrane protein 1 | 0.0229373 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0228952 |
| HELZ | helicase with zinc finger | 0.0225504 |
| SPG11 | spastic paraplegia 11 (autosomal recessive) | 0.0222871 |
| SP100 | SP100 nuclear antigen | 0.0222757 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0221285 |
| SETX | senataxin | 0.0221075 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.0220764 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.0219872 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0938722 |
| IGF2 | insulin-like growth factor 2 | -0.0848177 |
| COL3A1 | collagen, type III, alpha 1 | -0.0728689 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0683512 |
| VIM | vimentin | -0.0676768 |
| COL1A1 | collagen, type I, alpha 1 | -0.0666662 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.059457 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0573855 |
| NDRG1 | N-myc downstream regulated 1 | -0.0558842 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0468199 |
| MAP1B | microtubule-associated protein 1B | -0.0460139 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0455915 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0448387 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.042987 |
| ZNF804A | zinc finger protein 804A | -0.0396326 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0389186 |
| WDR45B | WD repeat domain 45B | -0.0379691 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0379128 |
| OGA | O-GlcNAcase | -0.0378551 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0374645 |
| GRB2 | growth factor receptor-bound protein 2 | -0.0374239 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0365209 |
| PTMA | prothymosin, alpha | -0.0362916 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0358484 |
| APP | amyloid beta (A4) precursor protein | -0.0351697 |
| NPR2 | natriuretic peptide receptor 2 | -0.0347104 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0344356 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0343795 |
| SEPTIN9 | septin 9 | -0.0343285 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.034017 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0328603 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0327572 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0327102 |
| TCF12 | transcription factor 12 | -0.0317351 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0316644 |
| ENO1 | enolase 1, (alpha) | -0.0316068 |
| PKM | pyruvate kinase, muscle | -0.0313911 |
| PCDH9 | protocadherin 9 | -0.0312967 |
| MXI1 | MAX interactor 1, dimerization protein | -0.031267 |
| RPS3 | ribosomal protein S3 | -0.0312151 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0305399 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.0304836 |
| FAM13A | family with sequence similarity 13, member A | -0.0303889 |
| RPS24 | ribosomal protein S24 | -0.0300121 |
| CADM1 | cell adhesion molecule 1 | -0.0296075 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.0293232 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.0291695 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0288976 |
| MYO1D | myosin ID | -0.0287926 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0280689 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0278759 |
| H3-3B | H3.3 histone B | -0.0274451 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0273415 |
| ATP13A3 | ATPase type 13A3 | -0.0272991 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0272662 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0271838 |
| NREP | neuronal regeneration related protein | -0.0271211 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0269805 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.026905 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0268026 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -0.0266853 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0265448 |
| MAP2K4 | mitogen-activated protein kinase kinase 4 | -0.0264925 |
| DST | dystonin | -0.0262944 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0262745 |
| QKI | QKI, KH domain containing, RNA binding | -0.0260425 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0260308 |
| CCDC47 | coiled-coil domain containing 47 | -0.0260123 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0256537 |
| NEK7 | NIMA-related kinase 7 | -0.0255399 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0254921 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0253542 |
| RLIM | ring finger protein, LIM domain interacting | -0.0252694 |
| IER3 | immediate early response 3 | -0.0252648 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0252137 |
| GPC5 | glypican 5 | -0.0252064 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0251979 |
| ACTG1 | actin gamma 1 | -0.024993 |
| COL18A1 | collagen, type XVIII, alpha 1 | -0.0249747 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0249685 |
| PLCB4 | phospholipase C, beta 4 | -0.0249485 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0247906 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0247282 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0246196 |
| ARHGAP9 | Rho GTPase activating protein 9 | -0.0245382 |
| DIAPH3 | diaphanous-related formin 3 | -0.0244971 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0243009 |
| ANXA2 | annexin A2 | -0.0242684 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0240104 |
| DTNA | dystrobrevin, alpha | -0.0238699 |
| PHF21A | PHD finger protein 21A | -0.0238095 |
| H1-0 | H1.0 linker histone | -0.0237706 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0237701 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.023725 |
| CUX1 | cut-like homeobox 1 | -0.0236593 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0236484 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -0.0235694 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0234232 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0233627 |
| AHNAK | AHNAK nucleoprotein | -0.0232691 |
