| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lenalidomide (hemihydrate) perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lenalidomide (hemihydrate)_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.174211 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.145455 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.111825 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.102627 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0878335 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0651057 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0544259 |
| B2M | beta-2-microglobulin | 0.0521471 |
| MT1X | metallothionein 1X | 0.0483901 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0480535 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0466785 |
| HLA-B | major histocompatibility complex, class I, B | 0.0427022 |
| FAM13A | family with sequence similarity 13, member A | 0.0403276 |
| DTNA | dystrobrevin, alpha | 0.0397356 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.038653 |
| PRELID2 | PRELI domain containing 2 | 0.0371872 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0357098 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0327048 |
| NDRG1 | N-myc downstream regulated 1 | 0.0308188 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0303765 |
| IGF2 | insulin-like growth factor 2 | 0.0297194 |
| GLRX | glutaredoxin (thioltransferase) | 0.0295788 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0294298 |
| STC1 | stanniocalcin 1 | 0.0288305 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.0274924 |
| HIP1 | huntingtin interacting protein 1 | 0.0274399 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0271706 |
| HLA-A | major histocompatibility complex, class I, A | 0.0270724 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0249589 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0248518 |
| RUNX1 | runt-related transcription factor 1 | 0.0245125 |
| MMP12 | matrix metallopeptidase 12 | 0.0243308 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0241304 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0230388 |
| CLEC1B | C-type lectin domain family 1, member B | 0.0223355 |
| RPL23 | ribosomal protein L23 | 0.0222615 |
| HDAC9 | histone deacetylase 9 | 0.0219422 |
| YEATS2 | YEATS domain containing 2 | 0.0211965 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0207755 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0207738 |
| RPL28 | ribosomal protein L28 | 0.0207205 |
| PCBP2 | poly(rC) binding protein 2 | 0.0206155 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0204091 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.020296 |
| RPL37A | ribosomal protein L37a | 0.0201559 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0199467 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0199163 |
| FAM219A | family with sequence similarity 219, member A | 0.0198685 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0197927 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0195917 |
| INSIG2 | insulin induced gene 2 | 0.019394 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.019093 |
| WWOX | WW domain containing oxidoreductase | 0.0189927 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0188899 |
| RPS19 | ribosomal protein S19 | 0.0188075 |
| SFXN1 | sideroflexin 1 | 0.0185606 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0183423 |
| C3 | complement component 3 | 0.018212 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0182053 |
| ZNF638 | zinc finger protein 638 | 0.0181713 |
| ARFGEF3 | ARFGEF family member 3 | 0.017729 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0174775 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0174339 |
| RELCH | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing | 0.017351 |
| MYO1B | myosin IB | 0.0172554 |
| FGF13 | fibroblast growth factor 13 | 0.0171937 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0171853 |
| NGLY1 | N-glycanase 1 | 0.0169912 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0168561 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.016637 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.0165428 |
| ZSWIM5 | zinc finger, SWIM-type containing 5 | 0.0164243 |
| STXBP1 | syntaxin binding protein 1 | 0.0163165 |
| VEGFC | vascular endothelial growth factor C | 0.0162545 |
| HELZ | helicase with zinc finger | 0.0162073 |
| RPS8 | ribosomal protein S8 | 0.0161653 |
| PYGL | phosphorylase, glycogen, liver | 0.0161494 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.016127 |
| RPS12 | ribosomal protein S12 | 0.0161012 |
| SRP54 | signal recognition particle 54kDa | 0.0159626 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) | 0.0156391 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | 0.0156026 |
| RPL34 | ribosomal protein L34 | 0.015576 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0155522 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | 0.0155203 |
| POM121 | POM121 transmembrane nucleoporin | 0.0154629 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | 0.0154066 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.01538 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0152752 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0152712 |
| CFAP96 | cilia and flagella associated protein 96 | 0.0152679 |
| RPS20 | ribosomal protein S20 | 0.0151307 |
| OXR1 | oxidation resistance 1 | 0.0151167 |
| CUL4B | cullin 4B | 0.0150557 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.014856 |
| HMGA2 | high mobility group AT-hook 2 | 0.0147437 |
| COL23A1 | collagen, type XXIII, alpha 1 | 0.0145464 |
| POM121C | POM121 transmembrane nucleoporin C | 0.0145153 |
| NPTN | neuroplastin | 0.014459 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.0143057 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.226652 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.159933 |
| COL6A3 | collagen, type VI, alpha 3 | -0.149058 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.114566 |
| TPM4 | tropomyosin 4 | -0.0987705 |
| DST | dystonin | -0.0950314 |
| MAP1B | microtubule-associated protein 1B | -0.0928628 |
| FN1 | fibronectin 1 | -0.0916084 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0881234 |
| AHNAK | AHNAK nucleoprotein | -0.0847878 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0833412 |
| FTL | ferritin, light polypeptide | -0.0773041 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0770192 |
| TMSB10 | thymosin beta 10 | -0.0741719 |
| EGFR | epidermal growth factor receptor | -0.0738768 |
| SBF2 | SET binding factor 2 | -0.0719221 |
| TNNC1 | troponin C type 1 (slow) | -0.0715645 |
| PTMA | prothymosin, alpha | -0.0660956 |
| CANX | calnexin | -0.0650239 |
| CADM1 | cell adhesion molecule 1 | -0.0649342 |
| VIM | vimentin | -0.0644664 |
| LDHA | lactate dehydrogenase A | -0.063552 |
| CALR | calreticulin | -0.0628122 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0617326 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0614828 |
| INHBA | inhibin, beta A | -0.0608135 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0584363 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0551528 |
| TNS3 | tensin 3 | -0.053922 |
| MAP4 | microtubule-associated protein 4 | -0.0523817 |
| ANXA2 | annexin A2 | -0.0523584 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | -0.0520377 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0520296 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0520127 |
| TENM3 | teneurin transmembrane protein 3 | -0.0517388 |
| LOX | lysyl oxidase | -0.0512335 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0511007 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0492587 |
| KYNU | kynureninase | -0.0468817 |
| STK17A | serine/threonine kinase 17a | -0.0463728 |
| HDLBP | high density lipoprotein binding protein | -0.0460968 |
| LRRC49 | leucine rich repeat containing 49 | -0.0460126 |
| VCL | vinculin | -0.0458444 |
| TXNRD1 | thioredoxin reductase 1 | -0.0453325 |
| VMP1 | vacuole membrane protein 1 | -0.0452887 |
| RTN4 | reticulon 4 | -0.04308 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0425916 |
| COG5 | component of oligomeric golgi complex 5 | -0.0418174 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0416557 |
| LYPD6B | LY6/PLAUR domain containing 6B | -0.0415168 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0413544 |
| RRBP1 | ribosome binding protein 1 | -0.0411114 |
| SCFD2 | sec1 family domain containing 2 | -0.0409039 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0403941 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0403806 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0396585 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0390054 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0377364 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0367467 |
| SQSTM1 | sequestosome 1 | -0.0365983 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0364055 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0360597 |
| SEC24D | SEC24 family member D | -0.0358019 |
| NF1 | neurofibromin 1 | -0.0342109 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0340582 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0339053 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0337107 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0319743 |
| FSTL1 | follistatin-like 1 | -0.031806 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0316968 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0313946 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0313217 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.031025 |
| JAZF1 | JAZF zinc finger 1 | -0.0309911 |
| POTEF | POTE ankyrin domain family, member F | -0.0308475 |
| CARS1 | cysteinyl-tRNA synthetase 1 | -0.0308319 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0303718 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0302381 |
| COL5A2 | collagen, type V, alpha 2 | -0.0299467 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0297864 |
| USP34 | ubiquitin specific peptidase 34 | -0.0293694 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0292273 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0290758 |
| CLIC4 | chloride intracellular channel 4 | -0.0287382 |
| FAM20C | family with sequence similarity 20, member C | -0.0280634 |
| GLIS3 | GLIS family zinc finger 3 | -0.0279153 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.027698 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0276907 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0275762 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0275057 |
| NABP1 | nucleic acid binding protein 1 | -0.0274084 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.0271773 |
| GOLGA3 | golgin A3 | -0.0269956 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0269824 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0269687 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0268427 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0268317 |
| AHR | aryl hydrocarbon receptor | -0.026364 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0263508 |
| TNPO1 | transportin 1 | -0.026105 |