| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lenalidomide (hemihydrate) perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lenalidomide (hemihydrate)_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.122714 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.106804 |
| PRELID2 | PRELI domain containing 2 | 0.0890564 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0712823 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0595989 |
| PKM | pyruvate kinase, muscle | 0.0572847 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0537195 |
| ACTG1 | actin gamma 1 | 0.0517305 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.048784 |
| GOLGA4 | golgin A4 | 0.0481534 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0454863 |
| SET | SET nuclear proto-oncogene | 0.043347 |
| ZNF638 | zinc finger protein 638 | 0.040898 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0390619 |
| PCBP2 | poly(rC) binding protein 2 | 0.0390268 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0384491 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0378686 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0371442 |
| RPS6 | ribosomal protein S6 | 0.0368767 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0364635 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0355029 |
| SPAG9 | sperm associated antigen 9 | 0.0354335 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0344144 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0338334 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0335565 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.032696 |
| ERBIN | erbb2 interacting protein | 0.0322969 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0321902 |
| RPL9 | ribosomal protein L9 | 0.0317725 |
| HELZ | helicase with zinc finger | 0.0316877 |
| RPS12 | ribosomal protein S12 | 0.0315993 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0313646 |
| RPS2 | ribosomal protein S2 | 0.0310465 |
| SNX9 | sorting nexin 9 | 0.0308577 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0307721 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0306397 |
| RCOR1 | REST corepressor 1 | 0.0304578 |
| RPL23 | ribosomal protein L23 | 0.0294124 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0288425 |
| RPS20 | ribosomal protein S20 | 0.0282973 |
| RAD51B | RAD51 paralog B | 0.0280421 |
| SEC24A | SEC24 family member A | 0.0280312 |
| SMAD3 | SMAD family member 3 | 0.0279406 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0277498 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0276522 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0275973 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0275326 |
| ZNF292 | zinc finger protein 292 | 0.0274991 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0273771 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0268717 |
| INTS6 | integrator complex subunit 6 | 0.0266929 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0266539 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0264221 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0263865 |
| CDCP1 | CUB domain containing protein 1 | 0.0260239 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0259322 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0258322 |
| UPP1 | uridine phosphorylase 1 | 0.0256578 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.02554 |
| SEPTIN7 | septin 7 | 0.025287 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0252747 |
| TUSC3 | tumor suppressor candidate 3 | 0.0251089 |
| GOLGB1 | golgin B1 | 0.0250518 |
| COG6 | component of oligomeric golgi complex 6 | 0.0249366 |
| SETD5 | SET domain containing 5 | 0.024812 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0246832 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0246163 |
| NDRG1 | N-myc downstream regulated 1 | 0.024527 |
| PTEN | phosphatase and tensin homolog | 0.0243223 |
| SCFD1 | sec1 family domain containing 1 | 0.0242172 |
| BRD2 | bromodomain containing 2 | 0.0241963 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0241819 |
| YEATS2 | YEATS domain containing 2 | 0.0241818 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0240923 |
| MED13 | mediator complex subunit 13 | 0.023476 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0234231 |
| ZNF207 | zinc finger protein 207 | 0.0231506 |
| ATXN1 | ataxin 1 | 0.0230671 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.022992 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0228298 |
| COPA | coatomer protein complex, subunit alpha | 0.0227901 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0224916 |
| MACROD2 | MACRO domain containing 2 | 0.0224236 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | 0.0223641 |
| RPLP1 | ribosomal protein, large, P1 | 0.0221685 |
| BBX | bobby sox homolog (Drosophila) | 0.0220059 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0219671 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0217095 |
| TJP1 | tight junction protein 1 | 0.0213829 |
| FAM13B | family with sequence similarity 13, member B | 0.0212416 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0210218 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0208861 |
| FBXO11 | F-box protein 11 | 0.020436 |
| RPS8 | ribosomal protein S8 | 0.0203285 |
| JMJD1C | jumonji domain containing 1C | 0.0203017 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0199197 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0198243 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.019804 |
| FNIP1 | folliculin interacting protein 1 | 0.0197903 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0197862 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.168733 |
| TMSB10 | thymosin beta 10 | -0.10148 |
| AHNAK | AHNAK nucleoprotein | -0.0911082 |
| ASPH | aspartate beta-hydroxylase | -0.084361 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0822763 |
| PTMA | prothymosin, alpha | -0.080352 |
| MKI67 | marker of proliferation Ki-67 | -0.0763637 |
| TMSB4X | thymosin beta 4, X-linked | -0.0750351 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | -0.0735942 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0706268 |
| ITGB8 | integrin, beta 8 | -0.0691291 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0689899 |
| PAX8 | paired box 8 | -0.0661348 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | -0.0660608 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0606948 |
| APP | amyloid beta (A4) precursor protein | -0.0581395 |
| H1-0 | H1.0 linker histone | -0.0564351 |
| LAMC2 | laminin, gamma 2 | -0.0533053 |
| VCAN | versican | -0.0490386 |
| MT2A | metallothionein 2A | -0.0481611 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0461826 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0450011 |
| LDHA | lactate dehydrogenase A | -0.0432272 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0419888 |
| RPL32 | ribosomal protein L32 | -0.0415544 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0414302 |
| POU5F1 | POU class 5 homeobox 1 | -0.0408499 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0405393 |
| ENO1 | enolase 1, (alpha) | -0.0404205 |
| SBF2 | SET binding factor 2 | -0.0389032 |
| LAMA4 | laminin, alpha 4 | -0.0376195 |
| ANXA2 | annexin A2 | -0.0373951 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0352158 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0349304 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0348932 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0341981 |
| KRT7 | keratin 7, type II | -0.0339423 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0337874 |
| EGR1 | early growth response 1 | -0.0336332 |
| KAZN | kazrin, periplakin interacting protein | -0.0322844 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0321566 |
| CLDN1 | claudin 1 | -0.0321488 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0320796 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | -0.0319119 |
| TXNRD1 | thioredoxin reductase 1 | -0.0309369 |
| TUBB | tubulin, beta class I | -0.0305835 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0304433 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0300683 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0299226 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0294421 |
| CCND1 | cyclin D1 | -0.029162 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0291303 |
| FIGN | fidgetin | -0.0291291 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0290385 |
| CDK12 | cyclin-dependent kinase 12 | -0.0289014 |
| DSG2 | desmoglein 2 | -0.0279527 |
| BICC1 | BicC family RNA binding protein 1 | -0.02774 |
| EZR | ezrin | -0.0273757 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0270991 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0269216 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.026867 |
| EREG | epiregulin | -0.0267143 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0264937 |
| TCF12 | transcription factor 12 | -0.0264817 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | -0.0264281 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0262688 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.025825 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0255787 |
| SDC4 | syndecan 4 | -0.0253607 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0253012 |
| KRT18 | keratin 18, type I | -0.0250754 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0249053 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0247174 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0247156 |
| HMGA2 | high mobility group AT-hook 2 | -0.0244049 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0243767 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.02432 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0242549 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0242339 |
| TUBA1B | tubulin, alpha 1b | -0.024133 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.0239009 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0237899 |
| TNS3 | tensin 3 | -0.0237803 |
| RASA3 | RAS p21 protein activator 3 | -0.0237326 |
| SSH2 | slingshot protein phosphatase 2 | -0.0237323 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0237146 |
| ATG7 | autophagy related 7 | -0.0236561 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.023524 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0232161 |
| ACTN4 | actinin, alpha 4 | -0.0231179 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0230893 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0230531 |
| HDLBP | high density lipoprotein binding protein | -0.0229593 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0227129 |
| NDUFAF2 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 | -0.0226257 |
| LMNA | lamin A/C | -0.0226129 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.02257 |
| DOCK3 | dedicator of cytokinesis 3 | -0.0224972 |
| DPP4 | dipeptidyl-peptidase 4 | -0.022426 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0224174 |
