| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lenalidomide (hemihydrate) perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lenalidomide (hemihydrate)_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.11972 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.100559 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0831589 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0738677 |
| NDRG1 | N-myc downstream regulated 1 | 0.0607199 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0564221 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0556269 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0537258 |
| RPS6 | ribosomal protein S6 | 0.0518772 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0472879 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0461271 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0444428 |
| TMEM165 | transmembrane protein 165 | 0.0426513 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0402827 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.039658 |
| ATP13A3 | ATPase type 13A3 | 0.0393472 |
| PTK2 | protein tyrosine kinase 2 | 0.0393096 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0392248 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0384045 |
| NAV2 | neuron navigator 2 | 0.0374216 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0363988 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0360262 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0352127 |
| HDAC9 | histone deacetylase 9 | 0.0349392 |
| ACTG1 | actin gamma 1 | 0.0346147 |
| VEGFA | vascular endothelial growth factor A | 0.0334276 |
| PDE10A | phosphodiesterase 10A | 0.0328912 |
| GRB10 | growth factor receptor-bound protein 10 | 0.032509 |
| PGK1 | phosphoglycerate kinase 1 | 0.0324712 |
| SVIL | supervillin | 0.0319908 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0318989 |
| RASA2 | RAS p21 protein activator 2 | 0.0318055 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0313873 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0311925 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0303812 |
| RUNX1 | runt-related transcription factor 1 | 0.0297306 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0293385 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0287511 |
| VIM | vimentin | 0.0279621 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0276786 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0275651 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0272842 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0272358 |
| VEGFC | vascular endothelial growth factor C | 0.0270315 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0267515 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0266268 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0266173 |
| JMJD1C | jumonji domain containing 1C | 0.0261564 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0261205 |
| SEC24A | SEC24 family member A | 0.0257605 |
| FOSL1 | FOS-like antigen 1 | 0.0254369 |
| URI1 | URI1, prefoldin-like chaperone | 0.0250916 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0244668 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0244202 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0241898 |
| ZNF148 | zinc finger protein 148 | 0.0241858 |
| PARD3 | par-3 family cell polarity regulator | 0.0239435 |
| RNF145 | ring finger protein 145 | 0.0238831 |
| SDC2 | syndecan 2 | 0.0237069 |
| TUBB6 | tubulin, beta 6 class V | 0.0235436 |
| NUMB | numb homolog (Drosophila) | 0.023367 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0232825 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0226083 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0217523 |
| NOTCH2 | notch 2 | 0.0216742 |
| MYADM | myeloid-associated differentiation marker | 0.0213591 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0213237 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0211837 |
| RTN4 | reticulon 4 | 0.0210836 |
| CDC27 | cell division cycle 27 | 0.0208969 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0208317 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0206745 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0205999 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0205622 |
| CLMP | CXADR-like membrane protein | 0.0204917 |
| HMGA2 | high mobility group AT-hook 2 | 0.0203704 |
| FBXO11 | F-box protein 11 | 0.0202895 |
| CD2AP | CD2-associated protein | 0.0201235 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0200117 |
| NRP1 | neuropilin 1 | 0.0198417 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.019805 |
| FBN1 | fibrillin 1 | 0.0196867 |
| HAS2 | hyaluronan synthase 2 | 0.0196194 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0194411 |
| ECE1 | endothelin converting enzyme 1 | 0.019322 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0192936 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0192634 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0191159 |
| FNBP1L | formin binding protein 1-like | 0.0190934 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0187353 |
| ANAPC5 | anaphase promoting complex subunit 5 | 0.0186908 |
| SRP54 | signal recognition particle 54kDa | 0.0185906 |
| RPL28 | ribosomal protein L28 | 0.0184582 |
| LRRC8C | leucine rich repeat containing 8 family, member C | 0.0183224 |
| USP34 | ubiquitin specific peptidase 34 | 0.0182221 |
| TUBB | tubulin, beta class I | 0.0181785 |
| ARRDC3 | arrestin domain containing 3 | 0.0181465 |
| WASHC4 | WASH complex subunit 4 | 0.0180922 |
| EZR | ezrin | 0.01801 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0179937 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.477002 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.348725 |
| COL1A1 | collagen, type I, alpha 1 | -0.100307 |
| CANX | calnexin | -0.0975389 |
| CALR | calreticulin | -0.0911348 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0740948 |
| CADM1 | cell adhesion molecule 1 | -0.07318 |
| UBC | ubiquitin C | -0.0725986 |
| COL5A1 | collagen, type V, alpha 1 | -0.07119 |
| ENO1 | enolase 1, (alpha) | -0.0689543 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0644358 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0621871 |
| COL3A1 | collagen, type III, alpha 1 | -0.0618039 |
| AHNAK | AHNAK nucleoprotein | -0.0596448 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0587731 |
| TMSB10 | thymosin beta 10 | -0.0569765 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0565211 |
| IER3 | immediate early response 3 | -0.0556651 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0532659 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0530054 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0498897 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0494312 |
| GOLGB1 | golgin B1 | -0.0484318 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0481844 |
| TPM4 | tropomyosin 4 | -0.0478218 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0456611 |
| HDLBP | high density lipoprotein binding protein | -0.0453693 |
| COL1A2 | collagen, type I, alpha 2 | -0.0452938 |
| PLEC | plectin | -0.0448595 |
| CLIC4 | chloride intracellular channel 4 | -0.0446786 |
| INHBA | inhibin, beta A | -0.0429001 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.042787 |
| IL6 | interleukin 6 | -0.0416868 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0402942 |
| SQSTM1 | sequestosome 1 | -0.0397578 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0391305 |
| LDHA | lactate dehydrogenase A | -0.0390357 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0389429 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0373105 |
| PALLD | palladin, cytoskeletal associated protein | -0.0372081 |
| APP | amyloid beta (A4) precursor protein | -0.0371412 |
| IRF1 | interferon regulatory factor 1 | -0.0363888 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0355311 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0353993 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.034735 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0345564 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0337921 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0333956 |
| RPS27A | ribosomal protein S27a | -0.0329478 |
| COL6A3 | collagen, type VI, alpha 3 | -0.032782 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0324779 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0322208 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0317693 |
| COL5A2 | collagen, type V, alpha 2 | -0.0315492 |
| CD44 | CD44 molecule (Indian blood group) | -0.0305113 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0299382 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0297987 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0293382 |
| FLNA | filamin A, alpha | -0.0293273 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0293226 |
| SEC24D | SEC24 family member D | -0.029189 |
| OSMR | oncostatin M receptor | -0.0290917 |
| VEPH1 | ventricular zone expressed PH domain-containing 1 | -0.02891 |
| IL6ST | interleukin 6 signal transducer | -0.0281509 |
| CALU | calumenin | -0.0278254 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.027226 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0271806 |
| RACK1 | receptor for activated C kinase 1 | -0.0270048 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0265794 |
| SMYD3 | SET and MYND domain containing 3 | -0.0253622 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0250334 |
| PTMA | prothymosin, alpha | -0.0248052 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0247759 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0246944 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0245795 |
| NEK10 | NIMA-related kinase 10 | -0.0237527 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0236587 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0230656 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0229614 |
| MTSS1 | metastasis suppressor 1 | -0.022625 |
| RPS3 | ribosomal protein S3 | -0.0225513 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0224893 |
| INTS6 | integrator complex subunit 6 | -0.0224408 |
| SRGN | serglycin | -0.0223343 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0222595 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.0220217 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0219056 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0214617 |
| NABP1 | nucleic acid binding protein 1 | -0.0212835 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.021071 |
| SCFD2 | sec1 family domain containing 2 | -0.0210137 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0209518 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0207992 |
| MMP3 | matrix metallopeptidase 3 | -0.0207845 |
| CMIP | c-Maf inducing protein | -0.0206727 |
| GANAB | glucosidase, alpha; neutral AB | -0.0206534 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0200078 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0199325 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.0198204 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0195962 |
