| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lenalidomide (hemihydrate) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lenalidomide (hemihydrate)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.162015 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0989602 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0828503 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0727298 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.070934 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0639364 |
| SMAD3 | SMAD family member 3 | 0.0613119 |
| TMC5 | transmembrane channel-like 5 | 0.0579348 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0553555 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0539771 |
| ATXN1 | ataxin 1 | 0.0520934 |
| BCL2L1 | BCL2-like 1 | 0.0511849 |
| FOXO1 | forkhead box O1 | 0.0478956 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0459056 |
| PDZD8 | PDZ domain containing 8 | 0.0458091 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0457805 |
| DST | dystonin | 0.0442376 |
| CD2AP | CD2-associated protein | 0.0420506 |
| NTN4 | netrin 4 | 0.0417292 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0411223 |
| BPTF | bromodomain PHD finger transcription factor | 0.0394746 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0377462 |
| FOXP1 | forkhead box P1 | 0.0372136 |
| TJP2 | tight junction protein 2 | 0.0350028 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0349204 |
| ETV6 | ets variant 6 | 0.0344983 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0343704 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0343243 |
| MYO1E | myosin IE | 0.0337489 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0334939 |
| POF1B | premature ovarian failure, 1B | 0.0333667 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0330984 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0324683 |
| FHL2 | four and a half LIM domains 2 | 0.0323541 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0323065 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0318246 |
| SEPTIN9 | septin 9 | 0.0315013 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0312503 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0311626 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0306827 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0303729 |
| TMEM45B | transmembrane protein 45B | 0.0299681 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0298468 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0298251 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0297633 |
| CLIC5 | chloride intracellular channel 5 | 0.0293259 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.0292219 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0291276 |
| KIAA0232 | KIAA0232 | 0.0289211 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0288269 |
| PPL | periplakin | 0.0277365 |
| UTRN | utrophin | 0.0274078 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | 0.0273213 |
| PHLPP2 | PH domain and leucine rich repeat protein phosphatase 2 | 0.0272386 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0271282 |
| RPL13A | ribosomal protein L13a | 0.0269753 |
| WWC1 | WW and C2 domain containing 1 | 0.0266874 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0265584 |
| TRIB1 | tribbles pseudokinase 1 | 0.0259563 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.025834 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.025546 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.024916 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0247853 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0246907 |
| RAB10 | RAB10, member RAS oncogene family | 0.0245768 |
| MYO9A | myosin IXA | 0.0244463 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0243952 |
| EXPH5 | exophilin 5 | 0.0243884 |
| RPL4 | ribosomal protein L4 | 0.024313 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0240507 |
| ZNF638 | zinc finger protein 638 | 0.02404 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0240264 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0238213 |
| FBXO11 | F-box protein 11 | 0.0234199 |
| NUCB2 | nucleobindin 2 | 0.0233561 |
| MED13 | mediator complex subunit 13 | 0.0228843 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0228804 |
| GLCCI1 | glucocorticoid induced 1 | 0.0227902 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0227824 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0226114 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0222494 |
| FLNB | filamin B, beta | 0.0222188 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.02218 |
| PLSCR1 | phospholipid scramblase 1 | 0.0218523 |
| DUSP16 | dual specificity phosphatase 16 | 0.0216428 |
| CAB39 | calcium binding protein 39 | 0.0215565 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0214329 |
| CYRIB | CYFIP related Rac1 interactor B | 0.0213778 |
| SHROOM3 | shroom family member 3 | 0.0213318 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.0212793 |
| TAF2 | TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa | 0.0212566 |
| CTBP2 | C-terminal binding protein 2 | 0.0209579 |
| PGK1 | phosphoglycerate kinase 1 | 0.0209561 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.020838 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0207624 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0206766 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0206369 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0203535 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0203406 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0202834 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.193455 |
| LYZ | lysozyme | -0.150844 |
| ANXA2 | annexin A2 | -0.116967 |
| PTMA | prothymosin, alpha | -0.105383 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.102314 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0964077 |
| POTEF | POTE ankyrin domain family, member F | -0.092992 |
| EZR | ezrin | -0.0878048 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0792081 |
| FTL | ferritin, light polypeptide | -0.0784478 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0774067 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0753333 |
| SQSTM1 | sequestosome 1 | -0.0706915 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0680724 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0607862 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0601898 |
| TMSB10 | thymosin beta 10 | -0.0584229 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0581086 |
| YBX1 | Y box binding protein 1 | -0.0556214 |
| LAMA4 | laminin, alpha 4 | -0.0555945 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0553 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0552063 |
| EGR1 | early growth response 1 | -0.0542854 |
| JUN | jun proto-oncogene | -0.0540113 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0525975 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0524626 |
| FBXO32 | F-box protein 32 | -0.0520178 |
| WASF2 | WAS protein family, member 2 | -0.0512879 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0512189 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0509305 |
| DIAPH2 | diaphanous-related formin 2 | -0.0507057 |
| TUFT1 | tuftelin 1 | -0.0496002 |
| INTS6 | integrator complex subunit 6 | -0.0488952 |
| VEGFA | vascular endothelial growth factor A | -0.0482137 |
| ACTN4 | actinin, alpha 4 | -0.0475698 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0475245 |
| MKI67 | marker of proliferation Ki-67 | -0.0466441 |
| MCL1 | myeloid cell leukemia 1 | -0.0465365 |
| LDHA | lactate dehydrogenase A | -0.0464823 |
| KRT20 | keratin 20, type I | -0.045454 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0444903 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0439515 |
| BBX | bobby sox homolog (Drosophila) | -0.0436362 |
| FOSL1 | FOS-like antigen 1 | -0.0428943 |
| ANXA1 | annexin A1 | -0.042633 |
| CENPF | centromere protein F, 350/400kDa | -0.0425876 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0425375 |
| TSC22D2 | TSC22 domain family, member 2 | -0.042437 |
| FOXO3 | forkhead box O3 | -0.0423093 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0422963 |
| RPL21 | ribosomal protein L21 | -0.0421353 |
| ARF4 | ADP-ribosylation factor 4 | -0.041983 |
| CCNL1 | cyclin L1 | -0.0419451 |
| S100A10 | S100 calcium binding protein A10 | -0.0413691 |
| HMGA1 | high mobility group AT-hook 1 | -0.0412354 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0412322 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0411756 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0372604 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.037254 |
| VMP1 | vacuole membrane protein 1 | -0.0369411 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0361457 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0356128 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0355871 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0353977 |
| DSPP | dentin sialophosphoprotein | -0.0352987 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0348082 |
| SPAG9 | sperm associated antigen 9 | -0.0339922 |
| PERP | PERP, TP53 apoptosis effector | -0.0337298 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0336615 |
| INSIG1 | insulin induced gene 1 | -0.0334368 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | -0.0333699 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.033237 |
| KRT8 | keratin 8, type II | -0.033134 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0330675 |
| JUP | junction plakoglobin | -0.0330245 |
| GOLGA4 | golgin A4 | -0.0328607 |
| MORF4L2 | mortality factor 4 like 2 | -0.0320392 |
| HMGB1 | high mobility group box 1 | -0.0319839 |
| SDC4 | syndecan 4 | -0.0319629 |
| PTK2 | protein tyrosine kinase 2 | -0.0319039 |
| S100A6 | S100 calcium binding protein A6 | -0.0319 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0318435 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0316088 |
| FAM13A | family with sequence similarity 13, member A | -0.0307249 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.030396 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0303257 |
| RPL23 | ribosomal protein L23 | -0.0301087 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0297521 |
| RYBP | RING1 and YY1 binding protein | -0.0294578 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0292008 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0290013 |
| PRKCA | protein kinase C, alpha | -0.028855 |
| LNX2 | ligand of numb-protein X 2 | -0.0287471 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0287155 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0285251 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0284637 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0284503 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0283927 |
| ANLN | anillin, actin binding protein | -0.0283522 |
| MAPK6 | mitogen-activated protein kinase 6 | -0.0283399 |
