| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lenalidomide (hemihydrate) perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lenalidomide (hemihydrate)_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYOF | myoferlin | 0.0875892 |
| MT2A | metallothionein 2A | 0.0642303 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0630872 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0610485 |
| LMO7 | LIM domain 7 | 0.059747 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0571182 |
| RPS6 | ribosomal protein S6 | 0.0524174 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0515062 |
| TXNIP | thioredoxin interacting protein | 0.0508124 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0504462 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0463381 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0447734 |
| EFHD2 | EF-hand domain family, member D2 | 0.0443706 |
| DOK5 | docking protein 5 | 0.0439821 |
| B2M | beta-2-microglobulin | 0.0436213 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0373704 |
| TGM2 | transglutaminase 2 | 0.0361824 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0340581 |
| BARX2 | BARX homeobox 2 | 0.0318322 |
| MEF2A | myocyte enhancer factor 2A | 0.0316396 |
| AOPEP | aminopeptidase O (putative) | 0.0304559 |
| DST | dystonin | 0.0285544 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0272317 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0265469 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0262264 |
| MT1X | metallothionein 1X | 0.0259602 |
| PCBP2 | poly(rC) binding protein 2 | 0.0256391 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0251529 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0247836 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0247366 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0245772 |
| ZNF292 | zinc finger protein 292 | 0.0239132 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0237549 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0237359 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0237333 |
| RNF145 | ring finger protein 145 | 0.0230871 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0226366 |
| ZNF638 | zinc finger protein 638 | 0.0226036 |
| CLU | clusterin | 0.0225644 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0222784 |
| ARRDC3 | arrestin domain containing 3 | 0.0221946 |
| PTEN | phosphatase and tensin homolog | 0.0218423 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0217563 |
| SMAD3 | SMAD family member 3 | 0.0217133 |
| TRAM1 | translocation associated membrane protein 1 | 0.0209198 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | 0.0208783 |
| NOTCH2 | notch 2 | 0.0208076 |
| MT1E | metallothionein 1E | 0.0207838 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.0207205 |
| JAG1 | jagged 1 | 0.020698 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.020283 |
| SIRT1 | sirtuin 1 | 0.0202081 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0200025 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0199955 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0196984 |
| GRAMD1B | GRAM domain containing 1B | 0.01968 |
| VEGFC | vascular endothelial growth factor C | 0.01964 |
| CMIP | c-Maf inducing protein | 0.019526 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0193158 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0192089 |
| SLK | STE20-like kinase | 0.0191501 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0190536 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0188494 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0187453 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0186347 |
| KIF16B | kinesin family member 16B | 0.0186134 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | 0.0182705 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0182564 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0180512 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0180162 |
| METTL15 | methyltransferase like 15 | 0.0179739 |
| IFI44L | interferon-induced protein 44-like | 0.0178778 |
| IRS2 | insulin receptor substrate 2 | 0.017598 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0175929 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0172577 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0172476 |
| CDK19 | cyclin-dependent kinase 19 | 0.0171495 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0170581 |
| TBC1D2 | TBC1 domain family, member 2 | 0.0170508 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0169866 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0169282 |
| PCDH1 | protocadherin 1 | 0.0167303 |
| JMJD1C | jumonji domain containing 1C | 0.0166057 |
| GOLGA4 | golgin A4 | 0.0164909 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0163484 |
| ATM | ATM serine/threonine kinase | 0.016307 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0162623 |
| XPO1 | exportin 1 | 0.01603 |
| TMF1 | TATA element modulatory factor 1 | 0.015884 |
| SIK3 | SIK family kinase 3 | 0.0158528 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0158474 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0157941 |
| HAS2 | hyaluronan synthase 2 | 0.0157413 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0154073 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0153666 |
| FAM13A | family with sequence similarity 13, member A | 0.0153083 |
| FTL | ferritin, light polypeptide | 0.0153079 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0151926 |
| VAPB | VAMP (vesicle-associated membrane protein)-associated protein B and C | 0.0150933 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0150628 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.253216 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.197943 |
| FLNB | filamin B, beta | -0.165438 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.109601 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.108798 |
| AHNAK | AHNAK nucleoprotein | -0.108267 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0976638 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0939903 |
| SULF1 | sulfatase 1 | -0.0881807 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0864337 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0803993 |
| LAMC2 | laminin, gamma 2 | -0.0789735 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0767812 |
| VCL | vinculin | -0.0741052 |
| PODXL | podocalyxin-like | -0.0726767 |
| ANXA2 | annexin A2 | -0.0719422 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0673463 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0672231 |
| EMP1 | epithelial membrane protein 1 | -0.0668291 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0646146 |
| MTSS1 | metastasis suppressor 1 | -0.0628107 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0608738 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0570375 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0555213 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0514258 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0513169 |
| KRT17 | keratin 17, type I | -0.050275 |
| PLEC | plectin | -0.050141 |
| PALLD | palladin, cytoskeletal associated protein | -0.0491358 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0490163 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0478421 |
| RCOR1 | REST corepressor 1 | -0.0477337 |
| PTMA | prothymosin, alpha | -0.0475249 |
| SULF2 | sulfatase 2 | -0.0465543 |
| S100A10 | S100 calcium binding protein A10 | -0.0464814 |
| NDRG1 | N-myc downstream regulated 1 | -0.0462799 |
| LDHA | lactate dehydrogenase A | -0.0460255 |
| ACTN4 | actinin, alpha 4 | -0.0457031 |
| THBD | thrombomodulin | -0.045126 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0446016 |
| CLIC4 | chloride intracellular channel 4 | -0.0442091 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0438598 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0437838 |
| BCL2L1 | BCL2-like 1 | -0.042851 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0424076 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0410937 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0407789 |
| CANX | calnexin | -0.0407784 |
| KRT6A | keratin 6A, type II | -0.0397561 |
| EGR1 | early growth response 1 | -0.0394445 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.039388 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0376489 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0374013 |
| RPS24 | ribosomal protein S24 | -0.0371854 |
| INTS6 | integrator complex subunit 6 | -0.0366594 |
| TMSB4X | thymosin beta 4, X-linked | -0.0355019 |
| CAVIN1 | caveolae associated protein 1 | -0.0353231 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0352923 |
| STC1 | stanniocalcin 1 | -0.0347143 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0342038 |
| LMNA | lamin A/C | -0.0337649 |
| OSMR | oncostatin M receptor | -0.0333902 |
| LDLR | low density lipoprotein receptor | -0.0332428 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0325542 |
| AMOTL1 | angiomotin like 1 | -0.0325311 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.0315456 |
| SQSTM1 | sequestosome 1 | -0.0311837 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0309069 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0306932 |
| HLA-E | major histocompatibility complex, class I, E | -0.0303966 |
| TPM4 | tropomyosin 4 | -0.0303524 |
| CD9 | CD9 molecule | -0.0300501 |
| H1-0 | H1.0 linker histone | -0.0299964 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0299923 |
| DUSP6 | dual specificity phosphatase 6 | -0.0297634 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0297629 |
| CDK6 | cyclin-dependent kinase 6 | -0.0297126 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0296965 |
| TNS3 | tensin 3 | -0.0290557 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0290016 |
| WASF2 | WAS protein family, member 2 | -0.028704 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0283484 |
| LUZP1 | leucine zipper protein 1 | -0.027787 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0273383 |
| FLNA | filamin A, alpha | -0.0272335 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0269051 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0267122 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.026624 |
| NAV2 | neuron navigator 2 | -0.0261275 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0259847 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0259319 |
| ACTG1 | actin gamma 1 | -0.0257477 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0256641 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0256093 |
| KRT14 | keratin 14, type I | -0.0255682 |
| SQLE | squalene epoxidase | -0.0253324 |
| CAPRIN2 | caprin family member 2 | -0.0251506 |
| RPS21 | ribosomal protein S21 | -0.0248074 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0247521 |
| RASAL2 | RAS protein activator like 2 | -0.024707 |