| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lenalidomide (hemihydrate) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lenalidomide (hemihydrate)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.247483 |
| CD44 | CD44 molecule (Indian blood group) | 0.127961 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.121365 |
| ERBIN | erbb2 interacting protein | 0.0876523 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0873039 |
| ANXA2 | annexin A2 | 0.0844045 |
| LDHA | lactate dehydrogenase A | 0.0790447 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0737092 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.064712 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0635784 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0609016 |
| VIM | vimentin | 0.0551422 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.054044 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.053897 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0537125 |
| VEGFC | vascular endothelial growth factor C | 0.0496126 |
| TLE4 | transducin-like enhancer of split 4 | 0.0484835 |
| INTS6 | integrator complex subunit 6 | 0.0479954 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.046843 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0462124 |
| DEK | DEK proto-oncogene | 0.0461247 |
| AHNAK | AHNAK nucleoprotein | 0.0457283 |
| PLSCR1 | phospholipid scramblase 1 | 0.0447825 |
| SET | SET nuclear proto-oncogene | 0.0437965 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0436135 |
| ACTG1 | actin gamma 1 | 0.0435119 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0422704 |
| RND3 | Rho family GTPase 3 | 0.0422609 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0419129 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0410979 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0410535 |
| BPTF | bromodomain PHD finger transcription factor | 0.0409645 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0406341 |
| PCBP2 | poly(rC) binding protein 2 | 0.0389703 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0380872 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0380387 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0379252 |
| VDAC1 | voltage-dependent anion channel 1 | 0.0377819 |
| ZNF432 | zinc finger protein 432 | 0.0377451 |
| ENO1 | enolase 1, (alpha) | 0.0377064 |
| PGK1 | phosphoglycerate kinase 1 | 0.0371901 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0369753 |
| PKM | pyruvate kinase, muscle | 0.0369557 |
| JMJD1C | jumonji domain containing 1C | 0.0366896 |
| ZNF841 | zinc finger protein 841 | 0.0366282 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0365382 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0364673 |
| RTN3 | reticulon 3 | 0.0362915 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0360111 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0358166 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0357908 |
| RUNX1 | runt-related transcription factor 1 | 0.0356659 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0356658 |
| CLIC4 | chloride intracellular channel 4 | 0.0355681 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0350489 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0350146 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0340984 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0337269 |
| VCL | vinculin | 0.0331797 |
| KLF12 | Kruppel-like factor 12 | 0.032885 |
| SP100 | SP100 nuclear antigen | 0.0327357 |
| RNF213 | ring finger protein 213 | 0.0325015 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.032493 |
| CCND1 | cyclin D1 | 0.0322945 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0322628 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | 0.0320597 |
| ZNF638 | zinc finger protein 638 | 0.0317802 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0317196 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.031429 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0312244 |
| VGLL3 | vestigial-like family member 3 | 0.0311836 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0308757 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0308207 |
| OXSR1 | oxidative stress responsive 1 | 0.0307019 |
| PRRC2C | proline-rich coiled-coil 2C | 0.030693 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0303703 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.03032 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0303116 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0302912 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0300705 |
| NAV1 | neuron navigator 1 | 0.0300375 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.030013 |
| RANBP17 | RAN binding protein 17 | 0.0299245 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0298627 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0298252 |
| CAVIN1 | caveolae associated protein 1 | 0.0297917 |
| TACC1 | transforming, acidic coiled-coil containing protein 1 | 0.029382 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0290569 |
| SPIDR | scaffolding protein involved in DNA repair | 0.029055 |
| SMYD3 | SET and MYND domain containing 3 | 0.0289242 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.028901 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0286783 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0286744 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0283483 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0282823 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.0282407 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0282379 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.027981 |
| RTN4 | reticulon 4 | 0.0279175 |
| NAV2 | neuron navigator 2 | 0.0278632 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.122834 |
| FN1 | fibronectin 1 | -0.115372 |
| COL5A1 | collagen, type V, alpha 1 | -0.0701901 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0663469 |
| GLIS3 | GLIS family zinc finger 3 | -0.0629618 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0601042 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0549387 |
| SLC12A8 | solute carrier family 12, member 8 | -0.0535626 |
| POTEF | POTE ankyrin domain family, member F | -0.0520016 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0496965 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0469631 |
| ZNF804A | zinc finger protein 804A | -0.0450141 |
| PLCB4 | phospholipase C, beta 4 | -0.0448223 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0446192 |
| CCBE1 | collagen and calcium binding EGF domains 1 | -0.0441128 |
| SBF2 | SET binding factor 2 | -0.0429155 |
| FLNA | filamin A, alpha | -0.042368 |
| CALR | calreticulin | -0.0412436 |
| FTL | ferritin, light polypeptide | -0.0379674 |
| VMP1 | vacuole membrane protein 1 | -0.0378588 |
| TMSB10 | thymosin beta 10 | -0.0370103 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0362691 |
| SUCO | SUN domain containing ossification factor | -0.0360622 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0355981 |
| PTMA | prothymosin, alpha | -0.0340694 |
| VEGFA | vascular endothelial growth factor A | -0.0337723 |
| TNS3 | tensin 3 | -0.0336564 |
| MKI67 | marker of proliferation Ki-67 | -0.0327333 |
| NDRG1 | N-myc downstream regulated 1 | -0.0323167 |
| SULF1 | sulfatase 1 | -0.0321233 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0308739 |
| ARF4 | ADP-ribosylation factor 4 | -0.0305375 |
| UBQLN1 | ubiquilin 1 | -0.0302301 |
| POSTN | periostin, osteoblast specific factor | -0.0301 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0299583 |
| ATP13A3 | ATPase type 13A3 | -0.0292503 |
| H1-4 | H1.4 linker histone, cluster member | -0.0288679 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0287641 |
| NRXN3 | neurexin 3 | -0.028682 |
| MAPRE1 | microtubule-associated protein, RP/EB family, member 1 | -0.0285927 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.028479 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0283767 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0280983 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0278269 |
| DENND1A | DENN/MADD domain containing 1A | -0.0277315 |
| GOLGA3 | golgin A3 | -0.0274017 |
| TRPC4 | transient receptor potential cation channel, subfamily C, member 4 | -0.0273524 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.026931 |
| TGFB2 | transforming growth factor, beta 2 | -0.0269044 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0268159 |
| CLTC | clathrin, heavy chain (Hc) | -0.0266788 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0266434 |
| BRD4 | bromodomain containing 4 | -0.0257006 |
| TOX | thymocyte selection-associated high mobility group box | -0.0256674 |
| COL5A2 | collagen, type V, alpha 2 | -0.0254737 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0251927 |
| TMEM178B | transmembrane protein 178B | -0.0251092 |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa | -0.0249983 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0249865 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0246208 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | -0.0242375 |
| NECTIN3 | nectin cell adhesion molecule 3 | -0.0239825 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | -0.0234716 |
| ZNF292 | zinc finger protein 292 | -0.023266 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0231459 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0229865 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | -0.0229023 |
| KLC1 | kinesin light chain 1 | -0.0226914 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0225662 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.0225376 |
| CTSD | cathepsin D | -0.0223467 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0219153 |
| FAR1 | fatty acyl CoA reductase 1 | -0.0218277 |
| SPAG9 | sperm associated antigen 9 | -0.0217307 |
| CAST | calpastatin | -0.0213649 |
| RLIM | ring finger protein, LIM domain interacting | -0.0212751 |
| CENPF | centromere protein F, 350/400kDa | -0.0212169 |
| PFKP | phosphofructokinase, platelet | -0.0211026 |
| PLEC | plectin | -0.0206598 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | -0.0205615 |
| ANLN | anillin, actin binding protein | -0.0204695 |
| GOLT1B | golgi transport 1B | -0.0204091 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | -0.0204013 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | -0.0203738 |
| SRSF4 | serine/arginine-rich splicing factor 4 | -0.0202529 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0201671 |
| MT1X | metallothionein 1X | -0.0200669 |
| SEC22B | SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) | -0.0200178 |
| NUMA1 | nuclear mitotic apparatus protein 1 | -0.0198782 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0198276 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0197834 |
| GPR107 | G protein-coupled receptor 107 | -0.0196871 |
| CCDC14 | coiled-coil domain containing 14 | -0.0196744 |
| LYPD6B | LY6/PLAUR domain containing 6B | -0.01958 |
| KIAA1958 | KIAA1958 | -0.0195375 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0194943 |
| WDR37 | WD repeat domain 37 | -0.0194844 |
| ATXN2 | ataxin 2 | -0.0191176 |
| NUP214 | nucleoporin 214kDa | -0.018967 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0189317 |
