| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lenalidomide (hemihydrate) perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lenalidomide (hemihydrate)_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYO1E | myosin IE | 0.0802879 |
| AREG | amphiregulin | 0.0588643 |
| FBXO11 | F-box protein 11 | 0.0541723 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0501926 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0467638 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0382605 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0368229 |
| RPS19 | ribosomal protein S19 | 0.0362606 |
| RNF145 | ring finger protein 145 | 0.0360417 |
| RPLP0 | ribosomal protein, large, P0 | 0.0353405 |
| CLDN4 | claudin 4 | 0.0339756 |
| SLC6A20 | solute carrier family 6 (proline IMINO transporter), member 20 | 0.0336585 |
| RPS13 | ribosomal protein S13 | 0.0333115 |
| DSG3 | desmoglein 3 | 0.032235 |
| DUSP5 | dual specificity phosphatase 5 | 0.0317107 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0315391 |
| RPS23 | ribosomal protein S23 | 0.0301307 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0292818 |
| RPS21 | ribosomal protein S21 | 0.0292567 |
| RPS8 | ribosomal protein S8 | 0.0287166 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0281442 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0268636 |
| RPL31 | ribosomal protein L31 | 0.0268411 |
| MT2A | metallothionein 2A | 0.0265066 |
| RCOR1 | REST corepressor 1 | 0.0263801 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0255188 |
| CLIC5 | chloride intracellular channel 5 | 0.0254689 |
| SPINK13 | serine peptidase inhibitor, Kazal type 13 (putative) | 0.0250518 |
| RPL35A | ribosomal protein L35a | 0.0248564 |
| RPS6 | ribosomal protein S6 | 0.0242518 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0239209 |
| S100P | S100 calcium binding protein P | 0.0237919 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | 0.0237342 |
| PCBP2 | poly(rC) binding protein 2 | 0.0233646 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0230873 |
| PDZD8 | PDZ domain containing 8 | 0.0229822 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0228751 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0223919 |
| RPL37A | ribosomal protein L37a | 0.0217349 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0216683 |
| RPL23 | ribosomal protein L23 | 0.0216168 |
| RPL11 | ribosomal protein L11 | 0.0212454 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0212245 |
| RPS17 | ribosomal protein S17 | 0.0206899 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0202684 |
| RPLP2 | ribosomal protein, large, P2 | 0.0200868 |
| INTS6 | integrator complex subunit 6 | 0.0199712 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0198738 |
| RPL36 | ribosomal protein L36 | 0.0193242 |
| CADPS2 | Ca++-dependent secretion activator 2 | 0.0191958 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0191882 |
| OXSR1 | oxidative stress responsive 1 | 0.0191738 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0191274 |
| FTL | ferritin, light polypeptide | 0.0191091 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0189161 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0188913 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0188566 |
| RPL29 | ribosomal protein L29 | 0.0188454 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0187541 |
| MACROD2 | MACRO domain containing 2 | 0.018731 |
| RPL9 | ribosomal protein L9 | 0.0185134 |
| PPP4R2 | protein phosphatase 4, regulatory subunit 2 | 0.0182244 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0181677 |
| RPS14 | ribosomal protein S14 | 0.0181354 |
| SAMD5 | sterile alpha motif domain containing 5 | 0.017932 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.0176769 |
| RPL28 | ribosomal protein L28 | 0.0171177 |
| TRAM1 | translocation associated membrane protein 1 | 0.0169656 |
| TSPAN8 | tetraspanin 8 | 0.0168297 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0165128 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0164312 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0162636 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.016056 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0158971 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0158533 |
| ST6GAL2 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 | 0.0155344 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.015484 |
| RANBP9 | RAN binding protein 9 | 0.0148572 |
| RNF43 | ring finger protein 43 | 0.0148266 |
| STRIP2 | striatin interacting protein 2 | 0.0147864 |
| GLCCI1 | glucocorticoid induced 1 | 0.0145716 |
| RPS10 | ribosomal protein S10 | 0.0145166 |
| RPS5 | ribosomal protein S5 | 0.0144843 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0143996 |
| DUSP4 | dual specificity phosphatase 4 | 0.0139477 |
| MCL1 | myeloid cell leukemia 1 | 0.0139021 |
| TIMM23B | translocase of inner mitochondrial membrane 23 homolog B (yeast) | 0.0138318 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0136365 |
| RPS27 | ribosomal protein S27 | 0.013585 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0135605 |
| WWOX | WW domain containing oxidoreductase | 0.0135103 |
| HLA-B | major histocompatibility complex, class I, B | 0.0134729 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0130646 |
| NPTN | neuroplastin | 0.0129503 |
| LMO7 | LIM domain 7 | 0.012867 |
| MT1X | metallothionein 1X | 0.0128461 |
| RPL7 | ribosomal protein L7 | 0.012815 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0127957 |
| CCNH | cyclin H | 0.0126845 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0124897 |
| Symbol | Name | Standardized Value |
|---|---|---|
| THSD4 | thrombospondin, type I, domain containing 4 | -0.192124 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.109639 |
| FLNB | filamin B, beta | -0.105667 |
| ANXA2 | annexin A2 | -0.101124 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0999241 |
| PTMA | prothymosin, alpha | -0.0997358 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0916821 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.084894 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0781554 |
| EZR | ezrin | -0.0762174 |
| LAMB3 | laminin, beta 3 | -0.0716047 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0711538 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0679817 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0660066 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0644771 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0631702 |
| FAT1 | FAT atypical cadherin 1 | -0.0631683 |
| PLAC8 | placenta-specific 8 | -0.060483 |
| ACTG1 | actin gamma 1 | -0.0568347 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0560184 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0552595 |
| DENND1A | DENN/MADD domain containing 1A | -0.0552507 |
| MSI2 | musashi RNA-binding protein 2 | -0.0549001 |
| CANX | calnexin | -0.053253 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0530613 |
| CALB1 | calbindin 1, 28kDa | -0.0529041 |
| AOPEP | aminopeptidase O (putative) | -0.0524044 |
| MX1 | MX dynamin-like GTPase 1 | -0.0522094 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0512478 |
| RRBP1 | ribosome binding protein 1 | -0.0500903 |
| DSG2 | desmoglein 2 | -0.0495667 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0472116 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0464758 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0456412 |
| HDLBP | high density lipoprotein binding protein | -0.0456204 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.045437 |
| MYOF | myoferlin | -0.0453792 |
| MKI67 | marker of proliferation Ki-67 | -0.0449372 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0446978 |
| RPS2 | ribosomal protein S2 | -0.0446953 |
| TCF12 | transcription factor 12 | -0.044414 |
| RPL4 | ribosomal protein L4 | -0.0440686 |
| RIGI | RNA sensor RIG-I | -0.0432159 |
| AHNAK | AHNAK nucleoprotein | -0.042333 |
| CUX1 | cut-like homeobox 1 | -0.0420908 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0419778 |
| ACTN4 | actinin, alpha 4 | -0.0408624 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0401425 |
| TPM4 | tropomyosin 4 | -0.0400579 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0396964 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0396512 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0394709 |
| IFRD1 | interferon-related developmental regulator 1 | -0.039074 |
| RNF213 | ring finger protein 213 | -0.03855 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0384065 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0383659 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0382549 |
| RAD51B | RAD51 paralog B | -0.0377325 |
| RPL13A | ribosomal protein L13a | -0.0376229 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0373476 |
| KRT18 | keratin 18, type I | -0.0369604 |
| KRT8 | keratin 8, type II | -0.0366109 |
| TRIM2 | tripartite motif containing 2 | -0.0363706 |
| ITGB4 | integrin, beta 4 | -0.0363593 |
| SQSTM1 | sequestosome 1 | -0.0363483 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.036309 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0361399 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0360344 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0357455 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0355536 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0348154 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0344101 |
| IRF1 | interferon regulatory factor 1 | -0.0336261 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0335094 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.033206 |
| XAF1 | XIAP associated factor 1 | -0.033096 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0327258 |
| WWC1 | WW and C2 domain containing 1 | -0.0324571 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.032138 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0318396 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | -0.0316656 |
| KIF5B | kinesin family member 5B | -0.0315218 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0315189 |
| VCL | vinculin | -0.0313075 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0313018 |
| SBF2 | SET binding factor 2 | -0.0312991 |
| PCDHB16 | protocadherin beta 16 | -0.0311965 |
| FERMT1 | fermitin family member 1 | -0.0311225 |
| SH3D19 | SH3 domain containing 19 | -0.0308958 |
| PIK3AP1 | phosphoinositide-3-kinase adaptor protein 1 | -0.0308183 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.030779 |
| MYO1D | myosin ID | -0.0307557 |
| RIN2 | Ras and Rab interactor 2 | -0.0307279 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0306598 |
| YBX1 | Y box binding protein 1 | -0.0304692 |
| RPL26 | ribosomal protein L26 | -0.0301623 |
| NPSR1 | neuropeptide S receptor 1 | -0.0300902 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | -0.0299313 |
| TXNRD1 | thioredoxin reductase 1 | -0.0295379 |
| COBL | cordon-bleu WH2 repeat protein | -0.0295302 |
