| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lenalidomide (hemihydrate) perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lenalidomide (hemihydrate)_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0788329 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0649726 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0508163 |
| LDHA | lactate dehydrogenase A | 0.0420927 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0354125 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0346085 |
| KRT7 | keratin 7, type II | 0.0344164 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0315949 |
| RPLP0 | ribosomal protein, large, P0 | 0.0299615 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0267612 |
| ENO1 | enolase 1, (alpha) | 0.0264401 |
| GRAMD1B | GRAM domain containing 1B | 0.0262619 |
| MYOF | myoferlin | 0.0260145 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0251896 |
| SEC61G | Sec61 gamma subunit | 0.0226537 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0224708 |
| CCND1 | cyclin D1 | 0.0210504 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0203884 |
| KRT18 | keratin 18, type I | 0.0201256 |
| IGF2 | insulin-like growth factor 2 | 0.0198363 |
| WWOX | WW domain containing oxidoreductase | 0.0192389 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0192327 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0188092 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0172877 |
| SCEL | sciellin | 0.0171921 |
| VEGFC | vascular endothelial growth factor C | 0.0165723 |
| DHX32 | DEAH (Asp-Glu-Ala-His) box polypeptide 32 | 0.0165133 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0163616 |
| RPL30 | ribosomal protein L30 | 0.0162692 |
| GPHN | gephyrin | 0.0159407 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0158813 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0157025 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | 0.0156443 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0155919 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0155057 |
| OCIAD2 | OCIA domain containing 2 | 0.0154909 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0153662 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.015175 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0151687 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0151369 |
| RPL9 | ribosomal protein L9 | 0.0151072 |
| ATF6 | activating transcription factor 6 | 0.0150044 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0148704 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | 0.0148271 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0146136 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.0144856 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0144835 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0142081 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0140554 |
| MAGEA4 | melanoma antigen family A4 | 0.0140417 |
| ATAD1 | ATPase family, AAA domain containing 1 | 0.0139643 |
| DST | dystonin | 0.0138463 |
| DNAJC10 | DnaJ (Hsp40) homolog, subfamily C, member 10 | 0.0134945 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0134677 |
| RPL7 | ribosomal protein L7 | 0.0133804 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.013209 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0131616 |
| ITSN2 | intersectin 2 | 0.0129544 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0129329 |
| NTN4 | netrin 4 | 0.0128806 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0126995 |
| SPCS3 | signal peptidase complex subunit 3 homolog (S. cerevisiae) | 0.0126665 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0126515 |
| FSIP2 | fibrous sheath interacting protein 2 | 0.0125659 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.0122592 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0122316 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.0121745 |
| CADPS2 | Ca++-dependent secretion activator 2 | 0.0120553 |
| DTNB | dystrobrevin, beta | 0.0119713 |
| TASOR2 | transcription activation suppressor family member 2 | 0.0119329 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0118392 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0118075 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0117595 |
| S100A11 | S100 calcium binding protein A11 | 0.0116549 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0114545 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0113845 |
| CDR2 | cerebellar degeneration-related protein 2, 62kDa | 0.0113281 |
| KRT19 | keratin 19, type I | 0.0111585 |
| IRS2 | insulin receptor substrate 2 | 0.0110482 |
| SET | SET nuclear proto-oncogene | 0.0109726 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0109654 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.01078 |
| XRRA1 | X-ray radiation resistance associated 1 | 0.0107184 |
| CLYBL | citrate lyase beta like | 0.0106056 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0105645 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0105509 |
| MTDH | metadherin | 0.0105363 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0105322 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.010493 |
| ABCE1 | ATP-binding cassette, sub-family E (OABP), member 1 | 0.0104744 |
| ABHD3 | abhydrolase domain containing 3 | 0.0104513 |
| TMED3 | transmembrane emp24 protein transport domain containing 3 | 0.0104151 |
| HM13 | histocompatibility (minor) 13 | 0.0103877 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0103701 |
| WDR43 | WD repeat domain 43 | 0.0103493 |
| CCAR1 | cell division cycle and apoptosis regulator 1 | 0.0103209 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0103119 |
| PSMD1 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | 0.0102809 |
| CAPN7 | calpain 7 | 0.0102666 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0102255 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | -0.113413 |
| NDRG1 | N-myc downstream regulated 1 | -0.106097 |
| CES1 | carboxylesterase 1 | -0.103858 |
| MCL1 | myeloid cell leukemia 1 | -0.0881982 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.071764 |
| ASPH | aspartate beta-hydroxylase | -0.0690694 |
| LAMC2 | laminin, gamma 2 | -0.0631667 |
| EGR1 | early growth response 1 | -0.0564109 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0540827 |
| H1-0 | H1.0 linker histone | -0.0539989 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0523611 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0514515 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.050381 |
| SPAG9 | sperm associated antigen 9 | -0.0481962 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0480304 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0433222 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0430455 |
| VMP1 | vacuole membrane protein 1 | -0.0427665 |
| LAMA4 | laminin, alpha 4 | -0.0414767 |
| HDLBP | high density lipoprotein binding protein | -0.0414665 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0398064 |
| RUNX1 | runt-related transcription factor 1 | -0.0397771 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0397699 |
| TMEM165 | transmembrane protein 165 | -0.0397208 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0393069 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0391214 |
| USP34 | ubiquitin specific peptidase 34 | -0.037395 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0368903 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0367465 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0362575 |
| RPS6 | ribosomal protein S6 | -0.0359379 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0355332 |
| OSMR | oncostatin M receptor | -0.0354892 |
| SBF2 | SET binding factor 2 | -0.0347388 |
| CCNL1 | cyclin L1 | -0.0347033 |
| MT2A | metallothionein 2A | -0.0346189 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | -0.0346041 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0344348 |
| TXNRD1 | thioredoxin reductase 1 | -0.034051 |
| PLEC | plectin | -0.0338042 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0335039 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0331183 |
| WASF2 | WAS protein family, member 2 | -0.0318419 |
| TMSB10 | thymosin beta 10 | -0.0314467 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0312795 |
| EFNA5 | ephrin-A5 | -0.0312548 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0306497 |
| EGFR | epidermal growth factor receptor | -0.0289148 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0287897 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.028731 |
| OGA | O-GlcNAcase | -0.0281482 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0280262 |
| PTMA | prothymosin, alpha | -0.0279804 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0277166 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0276256 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0273916 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0273132 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0272568 |
| NABP1 | nucleic acid binding protein 1 | -0.0272498 |
| LAMB3 | laminin, beta 3 | -0.0270971 |
| ANO6 | anoctamin 6 | -0.0269659 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0266962 |
| KLC1 | kinesin light chain 1 | -0.0266372 |
| GPC6 | glypican 6 | -0.0263746 |
| EZR | ezrin | -0.0262606 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0262049 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.026201 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0257743 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0257592 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0255912 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0254798 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0254445 |
| TPD52 | tumor protein D52 | -0.0253642 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0249026 |
| ABLIM1 | actin binding LIM protein 1 | -0.0248218 |
| NGLY1 | N-glycanase 1 | -0.0247383 |
| FRMD4B | FERM domain containing 4B | -0.0246764 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0243318 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0243297 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0241718 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0240861 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0240821 |
| RASA2 | RAS p21 protein activator 2 | -0.0238458 |
| NF1 | neurofibromin 1 | -0.0233456 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0230785 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0228472 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.02279 |
| MORF4L2 | mortality factor 4 like 2 | -0.0227204 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0223963 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | -0.0220709 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0219613 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0215219 |
| FLNB | filamin B, beta | -0.0215009 |
| PAPOLA | poly(A) polymerase alpha | -0.0214253 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0212708 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0212142 |
| ANXA2 | annexin A2 | -0.0211775 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0211105 |
| CUX1 | cut-like homeobox 1 | -0.0209287 |
| NCOA2 | nuclear receptor coactivator 2 | -0.0208871 |
