| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lenalidomide (hemihydrate) perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lenalidomide (hemihydrate)_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.14328 |
| PM20D1 | peptidase M20 domain containing 1 | 0.105519 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.090944 |
| GRAMD1B | GRAM domain containing 1B | 0.090595 |
| RPS6 | ribosomal protein S6 | 0.0676349 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0532127 |
| RBM25 | RNA binding motif protein 25 | 0.0476208 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0451723 |
| RPS29 | ribosomal protein S29 | 0.0446419 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0440164 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0439089 |
| RPLP1 | ribosomal protein, large, P1 | 0.0433451 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0433123 |
| TERF2IP | telomeric repeat binding factor 2, interacting protein | 0.0389183 |
| USP36 | ubiquitin specific peptidase 36 | 0.0371843 |
| MED13 | mediator complex subunit 13 | 0.0366882 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0366517 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0365601 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0356571 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0348542 |
| RPL35A | ribosomal protein L35a | 0.034455 |
| FBXO11 | F-box protein 11 | 0.0340184 |
| WWOX | WW domain containing oxidoreductase | 0.0339439 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0338462 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0337056 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0336876 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0335217 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.033497 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0322514 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0319694 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0315978 |
| MCL1 | myeloid cell leukemia 1 | 0.0313798 |
| JMJD1C | jumonji domain containing 1C | 0.030997 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0305088 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0304568 |
| RPS8 | ribosomal protein S8 | 0.030197 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0301928 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0296821 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0286499 |
| GPHN | gephyrin | 0.0285329 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0282251 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0279097 |
| MT1X | metallothionein 1X | 0.0275357 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0273552 |
| RPS27 | ribosomal protein S27 | 0.0271272 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0268188 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0268013 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0263163 |
| HLA-A | major histocompatibility complex, class I, A | 0.026188 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | 0.0261826 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0261694 |
| FLNB | filamin B, beta | 0.0261562 |
| PHIP | pleckstrin homology domain interacting protein | 0.0257523 |
| TPR | translocated promoter region, nuclear basket protein | 0.0254775 |
| GOLGA4 | golgin A4 | 0.0254706 |
| B2M | beta-2-microglobulin | 0.025338 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0251154 |
| SETD5 | SET domain containing 5 | 0.0251076 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0250596 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0249088 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0242628 |
| SVIL | supervillin | 0.0242577 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0240486 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0237159 |
| BMP6 | bone morphogenetic protein 6 | 0.0234901 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0230828 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0229765 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0227526 |
| ATP11A | ATPase, class VI, type 11A | 0.0225465 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0224893 |
| NEK7 | NIMA-related kinase 7 | 0.0223798 |
| PDE10A | phosphodiesterase 10A | 0.0222122 |
| PFDN2 | prefoldin subunit 2 | 0.0221916 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0221163 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0220579 |
| RBM6 | RNA binding motif protein 6 | 0.0220247 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | 0.0218301 |
| RNF145 | ring finger protein 145 | 0.0213409 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0209914 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0208561 |
| WDR43 | WD repeat domain 43 | 0.0206044 |
| SRPK2 | SRSF protein kinase 2 | 0.0205132 |
| RPL28 | ribosomal protein L28 | 0.0205036 |
| ACTG1 | actin gamma 1 | 0.0204665 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0203937 |
| EXT1 | exostosin glycosyltransferase 1 | 0.020279 |
| MATR3 | matrin 3 | 0.0202508 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0200809 |
| YLPM1 | YLP motif containing 1 | 0.0200683 |
| RPS20 | ribosomal protein S20 | 0.0199665 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.019784 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | 0.0197501 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.019631 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.019575 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0195202 |
| SLMAP | sarcolemma associated protein | 0.0195144 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0194061 |
| ITGB5 | integrin, beta 5 | 0.0193399 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0191532 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0191365 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.30274 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.292267 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.155816 |
| TMSB10 | thymosin beta 10 | -0.137266 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.105992 |
| FTL | ferritin, light polypeptide | -0.090722 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0905278 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0874751 |
| AHNAK | AHNAK nucleoprotein | -0.0863634 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.085464 |
| ASPH | aspartate beta-hydroxylase | -0.0848963 |
| FGB | fibrinogen beta chain | -0.0798704 |
| LDHA | lactate dehydrogenase A | -0.0795841 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0714168 |
| BICC1 | BicC family RNA binding protein 1 | -0.0705993 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0699786 |
| APP | amyloid beta (A4) precursor protein | -0.068847 |
| S100A6 | S100 calcium binding protein A6 | -0.0622945 |
| RPL19 | ribosomal protein L19 | -0.0594068 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0586905 |
| VIM | vimentin | -0.0583804 |
| TPM3 | tropomyosin 3 | -0.0582317 |
| UBC | ubiquitin C | -0.056439 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.054562 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0531215 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0482802 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0474972 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0460723 |
| ENO1 | enolase 1, (alpha) | -0.0456589 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0449637 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0447353 |
| PYGL | phosphorylase, glycogen, liver | -0.0435904 |
| NEGR1 | neuronal growth regulator 1 | -0.0434901 |
| DST | dystonin | -0.0432611 |
| OSMR | oncostatin M receptor | -0.042827 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.0425555 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0418617 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0418404 |
| DENND4A | DENN/MADD domain containing 4A | -0.0414031 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0413569 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0410722 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0405049 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0403028 |
| HDLBP | high density lipoprotein binding protein | -0.0399638 |
| RPS27A | ribosomal protein S27a | -0.0395133 |
| FLNA | filamin A, alpha | -0.038755 |
| YBX1 | Y box binding protein 1 | -0.0382927 |
| ANXA2 | annexin A2 | -0.0378517 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0374916 |
| UTRN | utrophin | -0.0370458 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0370161 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0362873 |
| CMIP | c-Maf inducing protein | -0.0356353 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.0354855 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0348362 |
| POTEF | POTE ankyrin domain family, member F | -0.0343644 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0339464 |
| PFN1 | profilin 1 | -0.033434 |
| EHBP1 | EH domain binding protein 1 | -0.0332373 |
| TAGLN2 | transgelin 2 | -0.0328521 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0323811 |
| THBS1 | thrombospondin 1 | -0.0323533 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.031898 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0316104 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0313568 |
| TPM1 | tropomyosin 1 (alpha) | -0.0312256 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0305116 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0298038 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0297862 |
| CALR | calreticulin | -0.029635 |
| CANX | calnexin | -0.0291115 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0290274 |
| CLDN1 | claudin 1 | -0.0287401 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | -0.0286683 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0285944 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0285845 |
| AHR | aryl hydrocarbon receptor | -0.028567 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0284001 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0282582 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0282447 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0281988 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0281391 |
| GLIS3 | GLIS family zinc finger 3 | -0.0281324 |
| TPM4 | tropomyosin 4 | -0.027958 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0279428 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0275635 |
| CFDP1 | craniofacial development protein 1 | -0.0274773 |
| RHOA | ras homolog family member A | -0.0274665 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0274173 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0273722 |
| VCL | vinculin | -0.0265984 |
| TUBA1B | tubulin, alpha 1b | -0.0265307 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0264748 |
| RACK1 | receptor for activated C kinase 1 | -0.0264427 |
| SDC4 | syndecan 4 | -0.0262888 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0262221 |
| ANLN | anillin, actin binding protein | -0.0260704 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0257835 |
| RPL4 | ribosomal protein L4 | -0.0252862 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | -0.0251139 |
