| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lenalidomide (hemihydrate) perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lenalidomide (hemihydrate)_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYO1E | myosin IE | 0.144699 |
| LMO7 | LIM domain 7 | 0.109779 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.10655 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.106265 |
| KYNU | kynureninase | 0.0932424 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0885151 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0842728 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0783056 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0680025 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0661738 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 | 0.0602209 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0599879 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0597665 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0596305 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.058598 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0581121 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0574779 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0563617 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0554589 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0550049 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0544556 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0535477 |
| CA12 | carbonic anhydrase XII | 0.0531511 |
| RNF149 | ring finger protein 149 | 0.0530774 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0530143 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0524893 |
| SERTAD2 | SERTA domain containing 2 | 0.0523532 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | 0.0522519 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0507689 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0507653 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0506951 |
| PLAUR | plasminogen activator, urokinase receptor | 0.050271 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0494567 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0493007 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0492041 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0491289 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0488694 |
| VCL | vinculin | 0.0488064 |
| STEAP4 | STEAP family member 4 | 0.0487047 |
| SIK3 | SIK family kinase 3 | 0.048108 |
| MYO6 | myosin VI | 0.0479356 |
| PRKCA | protein kinase C, alpha | 0.0478706 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0476809 |
| RNF213 | ring finger protein 213 | 0.0463778 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0459147 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0451233 |
| IRS2 | insulin receptor substrate 2 | 0.0448604 |
| OGA | O-GlcNAcase | 0.04455 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0444488 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0440361 |
| TXNRD1 | thioredoxin reductase 1 | 0.0439143 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0435653 |
| ACTN4 | actinin, alpha 4 | 0.0432589 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0432583 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0431993 |
| SVIL | supervillin | 0.0429787 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0418769 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0418374 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0418137 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0410057 |
| EFNA5 | ephrin-A5 | 0.0409489 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0406461 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.04061 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0402204 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0397107 |
| SON | SON DNA binding protein | 0.0396948 |
| RAD51B | RAD51 paralog B | 0.0395126 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0394462 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0393603 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0387173 |
| GRAMD1B | GRAM domain containing 1B | 0.0386918 |
| ASPH | aspartate beta-hydroxylase | 0.0385701 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0383251 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.037194 |
| SDC4 | syndecan 4 | 0.0371214 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0366843 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 0.0366168 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0365951 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0365524 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0363904 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.036356 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.036279 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0357763 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0356646 |
| MED13L | mediator complex subunit 13-like | 0.0355533 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0354607 |
| TXNIP | thioredoxin interacting protein | 0.0352853 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.035274 |
| MYO5B | myosin VB | 0.0352172 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0346362 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0344981 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0343985 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0339565 |
| HOMER1 | homer scaffolding protein 1 | 0.033748 |
| EGFR | epidermal growth factor receptor | 0.0334685 |
| EZR | ezrin | 0.0333958 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0332351 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0328625 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0325212 |
| AOPEP | aminopeptidase O (putative) | 0.032292 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.280141 |
| FN1 | fibronectin 1 | -0.203776 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.141725 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0973865 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0918058 |
| SPAG9 | sperm associated antigen 9 | -0.0769234 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0730012 |
| RPL26 | ribosomal protein L26 | -0.0697453 |
| VIM | vimentin | -0.0673402 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0628436 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0622289 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0609221 |
| ZNF292 | zinc finger protein 292 | -0.0606556 |
| PAPOLA | poly(A) polymerase alpha | -0.0583593 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0571403 |
| NPTN | neuroplastin | -0.0567972 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 | -0.0544512 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0543713 |
| RPL35A | ribosomal protein L35a | -0.0539359 |
| MUC16 | mucin 16, cell surface associated | -0.0537151 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0537077 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0518763 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.05136 |
| ABHD17C | abhydrolase domain containing 17C | -0.0510099 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | -0.0507055 |
| ATOSA | atos homolog A | -0.0495953 |
| FAM13A | family with sequence similarity 13, member A | -0.0494517 |
| RNF145 | ring finger protein 145 | -0.0491989 |
| MYO10 | myosin X | -0.0486598 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0482972 |
| LDHA | lactate dehydrogenase A | -0.0480435 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | -0.0470103 |
| B3GALNT2 | beta-1,3-N-acetylgalactosaminyltransferase 2 | -0.0469483 |
| S100A6 | S100 calcium binding protein A6 | -0.0468249 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0459785 |
| SFTPA2 | surfactant protein A2 | -0.0459367 |
| RPS25 | ribosomal protein S25 | -0.0454818 |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | -0.0449307 |
| RPS16 | ribosomal protein S16 | -0.0448965 |
| RPLP0 | ribosomal protein, large, P0 | -0.0447732 |
| MAP1B | microtubule-associated protein 1B | -0.044388 |
| MRTFA | myocardin related transcription factor A | -0.0438473 |
| RPS12 | ribosomal protein S12 | -0.043754 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.04336 |
| RPL12 | ribosomal protein L12 | -0.0432767 |
| MEF2A | myocyte enhancer factor 2A | -0.0430578 |
| ATF6 | activating transcription factor 6 | -0.0430086 |
| RHOA | ras homolog family member A | -0.0427268 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0425314 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0424138 |
| GOLGA4 | golgin A4 | -0.0423856 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0423035 |
| RACK1 | receptor for activated C kinase 1 | -0.0422116 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0421145 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0416535 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0412766 |
| FLNB | filamin B, beta | -0.0411665 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0410711 |
| TMSB10 | thymosin beta 10 | -0.0409612 |
| RPL9 | ribosomal protein L9 | -0.0408166 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0404205 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0402735 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0400128 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0398427 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0389841 |
| FAT1 | FAT atypical cadherin 1 | -0.0386725 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0368897 |
| OXSR1 | oxidative stress responsive 1 | -0.0367859 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.036777 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.03652 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0361082 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0360249 |
| IER3 | immediate early response 3 | -0.0359381 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0356915 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0356113 |
| STK17A | serine/threonine kinase 17a | -0.0345584 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0341346 |
| MEIS2 | Meis homeobox 2 | -0.0339694 |
| CDYL | chromodomain protein, Y-like | -0.0337237 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0333764 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0333641 |
| RPLP1 | ribosomal protein, large, P1 | -0.0332887 |
| ENO1 | enolase 1, (alpha) | -0.0332843 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0327785 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0326912 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0325481 |
| RPL5 | ribosomal protein L5 | -0.032465 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | -0.032436 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0324327 |
| KLF6 | Kruppel-like factor 6 | -0.0324232 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0323878 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0322806 |
| PTMA | prothymosin, alpha | -0.0321684 |
| RPS24 | ribosomal protein S24 | -0.0317856 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0317551 |
| POTEF | POTE ankyrin domain family, member F | -0.0316887 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0315707 |
| RPS6 | ribosomal protein S6 | -0.0315118 |
| ABI1 | abl-interactor 1 | -0.0314927 |
| MATR3 | matrin 3 | -0.031405 |
