| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lenalidomide (hemihydrate) perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lenalidomide (hemihydrate)_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.127343 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.105612 |
| TXNRD1 | thioredoxin reductase 1 | 0.0976156 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0905359 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0693821 |
| GRAMD1B | GRAM domain containing 1B | 0.063843 |
| RTN4 | reticulon 4 | 0.0587299 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0557176 |
| TMEM41B | transmembrane protein 41B | 0.0528426 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0522163 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0498681 |
| JMJD1C | jumonji domain containing 1C | 0.0489257 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.047653 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0457878 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0446779 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0445552 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0422871 |
| PCBP2 | poly(rC) binding protein 2 | 0.0414943 |
| FBXO11 | F-box protein 11 | 0.0412947 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.041283 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0392934 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0380219 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0370516 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0370282 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0363734 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0349848 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0345701 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.0339863 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0324898 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0315227 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0304222 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0301984 |
| PKM | pyruvate kinase, muscle | 0.0298698 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0293926 |
| ATP13A3 | ATPase type 13A3 | 0.0291696 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0284302 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0283475 |
| CDCP1 | CUB domain containing protein 1 | 0.0277322 |
| MSN | moesin | 0.027518 |
| WDR43 | WD repeat domain 43 | 0.0272639 |
| YAP1 | Yes-associated protein 1 | 0.0269955 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0269125 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0268001 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0263625 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0261313 |
| MMP12 | matrix metallopeptidase 12 | 0.0257733 |
| ATF6 | activating transcription factor 6 | 0.0251517 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0246893 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0238272 |
| RNF145 | ring finger protein 145 | 0.0237974 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0236842 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0234489 |
| CTTNBP2NL | CTTNBP2 N-terminal like | 0.0234251 |
| SNX9 | sorting nexin 9 | 0.0232367 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0232206 |
| SETX | senataxin | 0.0231633 |
| COPA | coatomer protein complex, subunit alpha | 0.0229673 |
| USP36 | ubiquitin specific peptidase 36 | 0.0226901 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0225583 |
| VMP1 | vacuole membrane protein 1 | 0.0223861 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0219447 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0215899 |
| BTBD10 | BTB (POZ) domain containing 10 | 0.0212558 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0212391 |
| NOTCH2 | notch 2 | 0.0210402 |
| ZNF638 | zinc finger protein 638 | 0.0208301 |
| HOMER1 | homer scaffolding protein 1 | 0.0206348 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0204035 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0203926 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0203773 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0201758 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0201268 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0200375 |
| CDK17 | cyclin-dependent kinase 17 | 0.0199689 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.019924 |
| BRD2 | bromodomain containing 2 | 0.0197911 |
| TBK1 | TANK-binding kinase 1 | 0.0197137 |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 | 0.019603 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0196 |
| ANXA5 | annexin A5 | 0.0195836 |
| POTEF | POTE ankyrin domain family, member F | 0.0192849 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.019278 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0188729 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0188265 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.018757 |
| ERBIN | erbb2 interacting protein | 0.0184171 |
| BRD4 | bromodomain containing 4 | 0.0181091 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.018073 |
| AFTPH | aftiphilin | 0.0180563 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0180347 |
| CALD1 | caldesmon 1 | 0.017945 |
| CDK13 | cyclin-dependent kinase 13 | 0.0179359 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0179001 |
| UBAP2 | ubiquitin associated protein 2 | 0.0178658 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0177068 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.0176855 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0176414 |
| TPM3 | tropomyosin 3 | 0.0175835 |
| HIPK3 | homeodomain interacting protein kinase 3 | 0.0175215 |
| TUBB6 | tubulin, beta 6 class V | 0.0175107 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.206431 |
| RAD51B | RAD51 paralog B | -0.131954 |
| TMSB10 | thymosin beta 10 | -0.127943 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.111912 |
| PTMA | prothymosin, alpha | -0.101474 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0983361 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0963944 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0830345 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0750512 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0715498 |
| EXOC4 | exocyst complex component 4 | -0.0673395 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0618014 |
| ATXN1 | ataxin 1 | -0.060342 |
| HMGA2 | high mobility group AT-hook 2 | -0.0597624 |
| RYR3 | ryanodine receptor 3 | -0.0594734 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0586797 |
| RPL12 | ribosomal protein L12 | -0.0581875 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0557865 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0553791 |
| RPS21 | ribosomal protein S21 | -0.0540455 |
| RPL26 | ribosomal protein L26 | -0.0540416 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0532267 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0507302 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0506804 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0452153 |
| RPL5 | ribosomal protein L5 | -0.0450576 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0432167 |
| RPS3 | ribosomal protein S3 | -0.0431587 |
| H1-0 | H1.0 linker histone | -0.0408039 |
| RNF213 | ring finger protein 213 | -0.0404513 |
| RPL32 | ribosomal protein L32 | -0.0404349 |
| PRELID2 | PRELI domain containing 2 | -0.0401602 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0400112 |
| FMN1 | formin 1 | -0.03985 |
| SBF2 | SET binding factor 2 | -0.0392203 |
| RPL23 | ribosomal protein L23 | -0.0389509 |
| BBX | bobby sox homolog (Drosophila) | -0.0386932 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0365015 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0356668 |
| RPS15 | ribosomal protein S15 | -0.0355579 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0350742 |
| RPLP2 | ribosomal protein, large, P2 | -0.0350107 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.034974 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0349316 |
| RPL19 | ribosomal protein L19 | -0.0349303 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0343112 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0341235 |
| RPL34 | ribosomal protein L34 | -0.0339223 |
| WWOX | WW domain containing oxidoreductase | -0.0335656 |
| RPL37 | ribosomal protein L37 | -0.0332698 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0330015 |
| ZNF217 | zinc finger protein 217 | -0.0325482 |
| AHNAK | AHNAK nucleoprotein | -0.0325144 |
| TPI1 | triosephosphate isomerase 1 | -0.0324029 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0323907 |
| YBX1 | Y box binding protein 1 | -0.0323712 |
| AEBP2 | AE binding protein 2 | -0.0320529 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0318826 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0316667 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.031507 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0314344 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0312378 |
| PFKP | phosphofructokinase, platelet | -0.031047 |
| SMYD3 | SET and MYND domain containing 3 | -0.0306921 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0300396 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0299807 |
| RPLP1 | ribosomal protein, large, P1 | -0.0297344 |
| SMAD3 | SMAD family member 3 | -0.029393 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0293231 |
| EFNA5 | ephrin-A5 | -0.0292461 |
| RPS19 | ribosomal protein S19 | -0.029182 |
| SSB | Sjogren syndrome antigen B (autoantigen La) | -0.028674 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0285321 |
| PDE10A | phosphodiesterase 10A | -0.028528 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0282189 |
| USP34 | ubiquitin specific peptidase 34 | -0.0281947 |
| RPL8 | ribosomal protein L8 | -0.0281738 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0280389 |
| PCNX1 | pecanex 1 | -0.0279492 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0278868 |
| KIAA1328 | KIAA1328 | -0.0278422 |
| RPS27 | ribosomal protein S27 | -0.0277682 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0273302 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0271369 |
| PFN1 | profilin 1 | -0.0270457 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0269697 |
| RACK1 | receptor for activated C kinase 1 | -0.0268855 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0268435 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0267936 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0267745 |
| MKI67 | marker of proliferation Ki-67 | -0.0264221 |
| CANX | calnexin | -0.0263831 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0262307 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0261998 |
| RPL13A | ribosomal protein L13a | -0.0259168 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0258497 |
| ATG7 | autophagy related 7 | -0.0255235 |
| DENND1A | DENN/MADD domain containing 1A | -0.0252556 |
| BSG | basigin (Ok blood group) | -0.0251973 |
| RPS24 | ribosomal protein S24 | -0.025138 |
