| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lenalidomide (hemihydrate) perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lenalidomide (hemihydrate)_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| UBC | ubiquitin C | 0.170646 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0818545 |
| RPS27A | ribosomal protein S27a | 0.0656542 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0625513 |
| UPP1 | uridine phosphorylase 1 | 0.0538738 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.052985 |
| RPL37A | ribosomal protein L37a | 0.052549 |
| FTL | ferritin, light polypeptide | 0.0522396 |
| PCBP2 | poly(rC) binding protein 2 | 0.0512356 |
| RPL9 | ribosomal protein L9 | 0.0499494 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0487427 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0473749 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.047173 |
| RPS12 | ribosomal protein S12 | 0.0431549 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0411129 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0389753 |
| RPS13 | ribosomal protein S13 | 0.0366877 |
| SET | SET nuclear proto-oncogene | 0.0364745 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0353357 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0347991 |
| RPS8 | ribosomal protein S8 | 0.034745 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0343091 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0329132 |
| MT2A | metallothionein 2A | 0.0323238 |
| RPS29 | ribosomal protein S29 | 0.0321719 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0320442 |
| RBM25 | RNA binding motif protein 25 | 0.0320133 |
| HLA-B | major histocompatibility complex, class I, B | 0.0297655 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.0293422 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0291733 |
| RPL37 | ribosomal protein L37 | 0.0288882 |
| RPL7 | ribosomal protein L7 | 0.0286424 |
| ZNF148 | zinc finger protein 148 | 0.0286032 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0284655 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0275473 |
| RPL30 | ribosomal protein L30 | 0.0274308 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.0271526 |
| HLA-A | major histocompatibility complex, class I, A | 0.0267841 |
| FBXO32 | F-box protein 32 | 0.0263935 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0256228 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0254876 |
| RPL15 | ribosomal protein L15 | 0.0253335 |
| MYO5B | myosin VB | 0.0248539 |
| PKM | pyruvate kinase, muscle | 0.0248473 |
| RPS17 | ribosomal protein S17 | 0.0248384 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.024779 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0247234 |
| RPS6 | ribosomal protein S6 | 0.0245106 |
| CNOT8 | CCR4-NOT transcription complex, subunit 8 | 0.0238462 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0238409 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0238269 |
| RPL23 | ribosomal protein L23 | 0.0231663 |
| RPS25 | ribosomal protein S25 | 0.022286 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0222573 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0221466 |
| FHIT | fragile histidine triad | 0.0218657 |
| ARRDC3 | arrestin domain containing 3 | 0.0217863 |
| FNBP4 | formin binding protein 4 | 0.0217636 |
| ENO1 | enolase 1, (alpha) | 0.0215717 |
| PPP2R5A | protein phosphatase 2, regulatory subunit B', alpha | 0.0214615 |
| TNPO1 | transportin 1 | 0.0212127 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0211409 |
| CLDN12 | claudin 12 | 0.0210577 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0209848 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0209425 |
| NEK7 | NIMA-related kinase 7 | 0.0206656 |
| MSN | moesin | 0.0206371 |
| GPC6 | glypican 6 | 0.0203578 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.020061 |
| TPM3 | tropomyosin 3 | 0.0199171 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0198673 |
| RAD51B | RAD51 paralog B | 0.0198523 |
| RPS10 | ribosomal protein S10 | 0.0197449 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0196489 |
| ANO6 | anoctamin 6 | 0.0196223 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0196117 |
| RPL31 | ribosomal protein L31 | 0.0195934 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0195448 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0193366 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0189811 |
| GPD2 | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) | 0.0189574 |
| NCKAP1 | NCK-associated protein 1 | 0.0188693 |
| LDHB | lactate dehydrogenase B | 0.018778 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0186565 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0186331 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0184715 |
| RTN4 | reticulon 4 | 0.0183651 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0183264 |
| RPLP1 | ribosomal protein, large, P1 | 0.0181714 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0180382 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0179692 |
| RPS27 | ribosomal protein S27 | 0.0179265 |
| FMNL2 | formin-like 2 | 0.0178646 |
| CD44 | CD44 molecule (Indian blood group) | 0.0177316 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.017658 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0175092 |
| RPS3 | ribosomal protein S3 | 0.0174698 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0172513 |
| CTSB | cathepsin B | 0.0170563 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | 0.0170232 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.264761 |
| ASPH | aspartate beta-hydroxylase | -0.132889 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.116407 |
| PTMA | prothymosin, alpha | -0.111568 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.111262 |
| LMO7 | LIM domain 7 | -0.108243 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0870461 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.081546 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0797322 |
| HMGA1 | high mobility group AT-hook 1 | -0.076969 |
| CCND1 | cyclin D1 | -0.0752499 |
| PLAU | plasminogen activator, urokinase | -0.0725386 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0723139 |
| TMSB10 | thymosin beta 10 | -0.0698774 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0675239 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0619718 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0599576 |
| ANXA2 | annexin A2 | -0.0593365 |
| AREG | amphiregulin | -0.058344 |
| ACTG1 | actin gamma 1 | -0.0565505 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0553073 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0552788 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0549304 |
| POTEF | POTE ankyrin domain family, member F | -0.0546077 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0541749 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0514785 |
| KRT7 | keratin 7, type II | -0.0514408 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0503443 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0493747 |
| COPA | coatomer protein complex, subunit alpha | -0.0492193 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0487087 |
| TMEM263 | transmembrane protein 263 | -0.0482216 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0479901 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0472844 |
| S100A10 | S100 calcium binding protein A10 | -0.0465447 |
| PGK1 | phosphoglycerate kinase 1 | -0.0465203 |
| RBM39 | RNA binding motif protein 39 | -0.0456533 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0455363 |
| WASF2 | WAS protein family, member 2 | -0.0454235 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0452475 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0449914 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0447454 |
| H1-0 | H1.0 linker histone | -0.0445285 |
| CD2AP | CD2-associated protein | -0.0444211 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0438036 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0435864 |
| FAM162A | family with sequence similarity 162, member A | -0.0433055 |
| RRBP1 | ribosome binding protein 1 | -0.0402123 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0400453 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0396027 |
| HDLBP | high density lipoprotein binding protein | -0.0394106 |
| TMEM123 | transmembrane protein 123 | -0.0390387 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0390166 |
| MORF4L2 | mortality factor 4 like 2 | -0.0389251 |
| SEC24D | SEC24 family member D | -0.0389211 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0388514 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0385078 |
| FAM13A | family with sequence similarity 13, member A | -0.0383796 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0380795 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0379447 |
| RLF | rearranged L-myc fusion | -0.0378995 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0378465 |
| ZNF292 | zinc finger protein 292 | -0.0377665 |
| LMNA | lamin A/C | -0.0372241 |
| GOLGA4 | golgin A4 | -0.0364733 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0364574 |
| EZR | ezrin | -0.0363825 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0357673 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0357032 |
| TOP1 | topoisomerase (DNA) I | -0.0356641 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0355753 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0352588 |
| ARF1 | ADP-ribosylation factor 1 | -0.035136 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.0349452 |
| CTSD | cathepsin D | -0.0342581 |
| DSG2 | desmoglein 2 | -0.0341331 |
| ANLN | anillin, actin binding protein | -0.0333021 |
| LAMC2 | laminin, gamma 2 | -0.0332994 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0329996 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0329828 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.032959 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0328996 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0325611 |
| CERT1 | ceramide transporter 1 | -0.0320126 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0317735 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0317323 |
| RUNX1 | runt-related transcription factor 1 | -0.0313413 |
| GNAS | GNAS complex locus | -0.0312407 |
| PAPOLA | poly(A) polymerase alpha | -0.0311977 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0305919 |
| MYOF | myoferlin | -0.030256 |
| RPL32 | ribosomal protein L32 | -0.030135 |
| QKI | QKI, KH domain containing, RNA binding | -0.0301347 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0299273 |
| TMSB4X | thymosin beta 4, X-linked | -0.0298068 |
| TPI1 | triosephosphate isomerase 1 | -0.0297076 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0294441 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0293927 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0288096 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0278203 |
