| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lenalidomide (hemihydrate) perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lenalidomide (hemihydrate)_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL8A1 | collagen, type VIII, alpha 1 | 0.128166 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.123924 |
| PM20D1 | peptidase M20 domain containing 1 | 0.113538 |
| DST | dystonin | 0.093549 |
| KYNU | kynureninase | 0.0666488 |
| PDLIM5 | PDZ and LIM domain 5 | 0.065091 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0629549 |
| GRAMD1B | GRAM domain containing 1B | 0.0615794 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0615479 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0586343 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0582637 |
| GDA | guanine deaminase | 0.0561005 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.050454 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0487 |
| UNC5D | unc-5 homolog D (C. elegans) | 0.0465329 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0460001 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.044111 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0441045 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0412515 |
| FMNL2 | formin-like 2 | 0.0388285 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0377338 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0374544 |
| CHL1 | cell adhesion molecule L1-like | 0.0371319 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0365439 |
| JMJD1C | jumonji domain containing 1C | 0.0365215 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | 0.0363639 |
| DNER | delta/notch-like EGF repeat containing | 0.0362409 |
| PTEN | phosphatase and tensin homolog | 0.0355333 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0338138 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0337758 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0319236 |
| SLC38A2 | solute carrier family 38, member 2 | 0.031641 |
| NFX1 | nuclear transcription factor, X-box binding 1 | 0.0316337 |
| TMEM144 | transmembrane protein 144 | 0.0315086 |
| STC1 | stanniocalcin 1 | 0.0310048 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0307571 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0306863 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit | 0.0302384 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0300949 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0294629 |
| RASAL2 | RAS protein activator like 2 | 0.029178 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0289972 |
| BPTF | bromodomain PHD finger transcription factor | 0.0286885 |
| COL4A6 | collagen, type IV, alpha 6 | 0.0286812 |
| CD44 | CD44 molecule (Indian blood group) | 0.027993 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0274549 |
| DUSP4 | dual specificity phosphatase 4 | 0.0273942 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0272944 |
| DISP1 | dispatched homolog 1 (Drosophila) | 0.0272474 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0269929 |
| ITGA6 | integrin, alpha 6 | 0.0269833 |
| PGM2L1 | phosphoglucomutase 2-like 1 | 0.0268283 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0264583 |
| HLA-A | major histocompatibility complex, class I, A | 0.0260757 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0255262 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0249471 |
| SCARA5 | scavenger receptor class A, member 5 | 0.0247252 |
| RPLP0 | ribosomal protein, large, P0 | 0.0246665 |
| PGK1 | phosphoglycerate kinase 1 | 0.024512 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | 0.0243438 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0242237 |
| ITGB8 | integrin, beta 8 | 0.0242048 |
| LDHA | lactate dehydrogenase A | 0.0239135 |
| CTSL | cathepsin L | 0.0234208 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0233984 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0226345 |
| RGS2 | regulator of G-protein signaling 2 | 0.0223909 |
| PCBP2 | poly(rC) binding protein 2 | 0.0221227 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0219695 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0217439 |
| TXNIP | thioredoxin interacting protein | 0.020843 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0207696 |
| NRDC | nardilysin convertase | 0.0207397 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0207354 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0205017 |
| MAP7 | microtubule-associated protein 7 | 0.0203671 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0203651 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0202836 |
| GPRIN3 | GPRIN family member 3 | 0.0202336 |
| KPNB1 | karyopherin (importin) beta 1 | 0.020166 |
| OXSR1 | oxidative stress responsive 1 | 0.0200713 |
| DENND1B | DENN/MADD domain containing 1B | 0.0198902 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0198864 |
| CLMP | CXADR-like membrane protein | 0.0198398 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0194922 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0190621 |
| KIAA0825 | KIAA0825 | 0.0189566 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0189489 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0188792 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.0188193 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0187093 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0186903 |
| MED13 | mediator complex subunit 13 | 0.0186837 |
| NSD1 | nuclear receptor binding SET domain protein 1 | 0.0185335 |
| ZNF638 | zinc finger protein 638 | 0.0184081 |
| EGR1 | early growth response 1 | 0.0184064 |
| B2M | beta-2-microglobulin | 0.0183404 |
| PHF14 | PHD finger protein 14 | 0.0183325 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0181941 |
| R3HDM2 | R3H domain containing 2 | 0.018115 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.158159 |
| FN1 | fibronectin 1 | -0.153738 |
| ASPH | aspartate beta-hydroxylase | -0.147989 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.132299 |
| CDH13 | cadherin 13 | -0.117213 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.116291 |
| TMSB10 | thymosin beta 10 | -0.1149 |
| EFNA5 | ephrin-A5 | -0.0977376 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0859977 |
| PTMA | prothymosin, alpha | -0.0834728 |
| PCBP3 | poly(rC) binding protein 3 | -0.0796614 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0756912 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0716736 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0711543 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | -0.0629886 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.058334 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0565052 |
| FTL | ferritin, light polypeptide | -0.0539368 |
| SMYD3 | SET and MYND domain containing 3 | -0.0533882 |
| RPL23 | ribosomal protein L23 | -0.0458669 |
| AUTS2 | autism susceptibility candidate 2 | -0.04586 |
| RPS24 | ribosomal protein S24 | -0.0405503 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0402152 |
| SPAG9 | sperm associated antigen 9 | -0.0400389 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0397055 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0397048 |
| LSAMP | limbic system-associated membrane protein | -0.0396052 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.038479 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0382189 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0371845 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0370742 |
| NCKAP5 | NCK-associated protein 5 | -0.0356354 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0354809 |
| RPL35A | ribosomal protein L35a | -0.0351511 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0335124 |
| FLNA | filamin A, alpha | -0.0328205 |
| VCL | vinculin | -0.0314739 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0309968 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0308351 |
| RPL34 | ribosomal protein L34 | -0.030469 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0294092 |
| GNAS | GNAS complex locus | -0.0292805 |
| RPS6 | ribosomal protein S6 | -0.0292422 |
| RAD51B | RAD51 paralog B | -0.0292255 |
| RPS19 | ribosomal protein S19 | -0.0290126 |
| RPL13A | ribosomal protein L13a | -0.0289714 |
| YBX1 | Y box binding protein 1 | -0.0284481 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0278348 |
| RPS21 | ribosomal protein S21 | -0.0278181 |
| RBM39 | RNA binding motif protein 39 | -0.0270632 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0270255 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0267866 |
| RRBP1 | ribosome binding protein 1 | -0.0267848 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0265399 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0264326 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | -0.0262758 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0262344 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0261759 |
| MKI67 | marker of proliferation Ki-67 | -0.0259699 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0258431 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0256924 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0256127 |
| RPS2 | ribosomal protein S2 | -0.0254578 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0253602 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0252525 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0252417 |
| SRGN | serglycin | -0.0249984 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.024772 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.024546 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0244631 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0238533 |
| MAP4 | microtubule-associated protein 4 | -0.0238493 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0238105 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | -0.0234274 |
| OGA | O-GlcNAcase | -0.0232271 |
| HDLBP | high density lipoprotein binding protein | -0.0231937 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0228665 |
| RPS23 | ribosomal protein S23 | -0.0228658 |
| RPL12 | ribosomal protein L12 | -0.0228033 |
| RPL26 | ribosomal protein L26 | -0.0227793 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0226624 |
| SLCO1C1 | solute carrier organic anion transporter family, member 1C1 | -0.022549 |
| CADM2 | cell adhesion molecule 2 | -0.0224469 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0223666 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0223068 |
| RPL5 | ribosomal protein L5 | -0.021995 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0218351 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0218142 |
| RPL35 | ribosomal protein L35 | -0.021719 |
| FUS | FUS RNA binding protein | -0.0216771 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0214558 |
| LAMA5 | laminin, alpha 5 | -0.0212002 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.02112 |
| SKP1 | S-phase kinase-associated protein 1 | -0.0211104 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0209092 |
| DENND1A | DENN/MADD domain containing 1A | -0.0208007 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0207781 |
| ANXA1 | annexin A1 | -0.0207296 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0206719 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0206614 |
