| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lenalidomide (hemihydrate) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lenalidomide (hemihydrate)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | 0.100907 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0834407 |
| RPL23 | ribosomal protein L23 | 0.0749822 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0666132 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0576226 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0548865 |
| RPL35A | ribosomal protein L35a | 0.0547878 |
| JMJD1C | jumonji domain containing 1C | 0.0508852 |
| PHIP | pleckstrin homology domain interacting protein | 0.0442109 |
| INTS6 | integrator complex subunit 6 | 0.0436947 |
| RCOR1 | REST corepressor 1 | 0.0430014 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0395618 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | 0.0381077 |
| WWOX | WW domain containing oxidoreductase | 0.0350864 |
| RPS6 | ribosomal protein S6 | 0.0350017 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0346084 |
| FOXP2 | forkhead box P2 | 0.033591 |
| IGF2 | insulin-like growth factor 2 | 0.0325697 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0323744 |
| SRPK2 | SRSF protein kinase 2 | 0.0323637 |
| SMYD3 | SET and MYND domain containing 3 | 0.0319055 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0316136 |
| RPS14 | ribosomal protein S14 | 0.0315217 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0309671 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.030904 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | 0.0308448 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0305093 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0303694 |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 | 0.0302223 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0296018 |
| RSF1 | remodeling and spacing factor 1 | 0.0295907 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0292886 |
| TRAK1 | trafficking protein, kinesin binding 1 | 0.0290418 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0289716 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0279976 |
| GPHN | gephyrin | 0.0278943 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0278186 |
| TMEM165 | transmembrane protein 165 | 0.0275398 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.027057 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0267567 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 0.0264907 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.026479 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0262906 |
| BPTF | bromodomain PHD finger transcription factor | 0.0262013 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | 0.0258144 |
| KLHL24 | kelch-like family member 24 | 0.0256648 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0255323 |
| RPS27A | ribosomal protein S27a | 0.0253937 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0253931 |
| BRD2 | bromodomain containing 2 | 0.0240348 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0239513 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0237038 |
| RAB7A | RAB7A, member RAS oncogene family | 0.023447 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.02329 |
| RAD51B | RAD51 paralog B | 0.0232062 |
| FTL | ferritin, light polypeptide | 0.0231705 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 0.0231563 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0230766 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0230432 |
| RPS8 | ribosomal protein S8 | 0.0230142 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0226848 |
| RPS16 | ribosomal protein S16 | 0.0226529 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0225049 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0224713 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0223944 |
| RPL9 | ribosomal protein L9 | 0.0223486 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0223239 |
| NXN | nucleoredoxin | 0.0221022 |
| RPS13 | ribosomal protein S13 | 0.0217292 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0216836 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0216529 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0214434 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0213882 |
| ZNF638 | zinc finger protein 638 | 0.021149 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0210674 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0207875 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | 0.0206505 |
| MAGT1 | magnesium transporter 1 | 0.0206368 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0206216 |
| AUTS2 | autism susceptibility candidate 2 | 0.0204857 |
| WDR44 | WD repeat domain 44 | 0.0204578 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.0203388 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0202162 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0201492 |
| RPL37A | ribosomal protein L37a | 0.0200821 |
| R3HDM1 | R3H domain containing 1 | 0.02004 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0200285 |
| CREBZF | CREB/ATF bZIP transcription factor | 0.019667 |
| FN1 | fibronectin 1 | 0.0196147 |
| MEF2C | myocyte enhancer factor 2C | 0.0194937 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0194617 |
| ITSN2 | intersectin 2 | 0.0194418 |
| SUN1 | Sad1 and UNC84 domain containing 1 | 0.0194104 |
| RPS27 | ribosomal protein S27 | 0.0193909 |
| SVIL | supervillin | 0.0193631 |
| SMAD2 | SMAD family member 2 | 0.0193343 |
| RPLP1 | ribosomal protein, large, P1 | 0.0192735 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0192653 |
| SYT1 | synaptotagmin I | 0.0192488 |
| CUX1 | cut-like homeobox 1 | 0.0191975 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.155129 |
| GPC3 | glypican 3 | -0.134751 |
| COL5A2 | collagen, type V, alpha 2 | -0.105609 |
| PEG10 | paternally expressed 10 | -0.0891622 |
| TMSB4X | thymosin beta 4, X-linked | -0.0874194 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0841584 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0807836 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0764945 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0736342 |
| POTEF | POTE ankyrin domain family, member F | -0.0733139 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0723912 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0723587 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0682913 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0672062 |
| COL3A1 | collagen, type III, alpha 1 | -0.0663821 |
| DST | dystonin | -0.0642114 |
| RPS2 | ribosomal protein S2 | -0.0632193 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0625011 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0597285 |
| ACTG1 | actin gamma 1 | -0.0583293 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0580674 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0575554 |
| RAI1 | retinoic acid induced 1 | -0.0571896 |
| ZNF292 | zinc finger protein 292 | -0.0556178 |
| CENPF | centromere protein F, 350/400kDa | -0.0549886 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0539575 |
| SET | SET nuclear proto-oncogene | -0.0536548 |
| CCN2 | cellular communication network factor 2 | -0.05228 |
| CFL2 | cofilin 2 (muscle) | -0.0513345 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0513015 |
| YBX1 | Y box binding protein 1 | -0.0507096 |
| MKI67 | marker of proliferation Ki-67 | -0.0506656 |
| NRG1 | neuregulin 1 | -0.0503867 |
| H1-0 | H1.0 linker histone | -0.050241 |
| CALR | calreticulin | -0.0501855 |
| H1-4 | H1.4 linker histone, cluster member | -0.0495263 |
| TPM3 | tropomyosin 3 | -0.048721 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0486769 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.047075 |
| SFRP4 | secreted frizzled-related protein 4 | -0.0469079 |
| ANXA1 | annexin A1 | -0.0452178 |
| ARHGAP15 | Rho GTPase activating protein 15 | -0.044847 |
| PDGFC | platelet derived growth factor C | -0.043898 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.043499 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.0434515 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0433783 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0429225 |
| HDAC2 | histone deacetylase 2 | -0.0427342 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0421206 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0407442 |
| ANXA5 | annexin A5 | -0.0406614 |
| LRRC4C | leucine rich repeat containing 4C | -0.0400861 |
| VIM | vimentin | -0.0393359 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.039047 |
| TXNRD1 | thioredoxin reductase 1 | -0.0386168 |
| THBS1 | thrombospondin 1 | -0.0385979 |
| EMP1 | epithelial membrane protein 1 | -0.038433 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0384175 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | -0.0379542 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0379086 |
| NTM | neurotrimin | -0.0377874 |
| RFPL4B | ret finger protein-like 4B | -0.0376439 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0372753 |
| CANX | calnexin | -0.0370229 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.036391 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0362548 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.0361426 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0360297 |
| PCDH7 | protocadherin 7 | -0.0357285 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0357059 |
| PAPOLA | poly(A) polymerase alpha | -0.0355823 |
| TPM1 | tropomyosin 1 (alpha) | -0.0353257 |
| USP3 | ubiquitin specific peptidase 3 | -0.0352355 |
| DMD | dystrophin | -0.0347176 |
| PDCD5 | programmed cell death 5 | -0.0341841 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.034099 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0340355 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0337917 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0336807 |
| OSBPL9 | oxysterol binding protein-like 9 | -0.0333811 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.033063 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | -0.0330311 |
| RPL6 | ribosomal protein L6 | -0.0329955 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | -0.0324326 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0321631 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | -0.0319927 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0317944 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0317023 |
| RPL7 | ribosomal protein L7 | -0.0316451 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | -0.0314701 |
| TCEA1 | transcription elongation factor A (SII), 1 | -0.0312589 |
| STMN1 | stathmin 1 | -0.0312169 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.0309743 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0309728 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.030648 |
| PCDH9 | protocadherin 9 | -0.0306174 |
| TUBA1B | tubulin, alpha 1b | -0.0304691 |
| PUM1 | pumilio RNA-binding family member 1 | -0.0304466 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | -0.0304053 |
| ANXA2 | annexin A2 | -0.0303492 |
