| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lenalidomide (hemihydrate) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lenalidomide (hemihydrate)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS16 | ribosomal protein S16 | 0.221805 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0904027 |
| INTS6 | integrator complex subunit 6 | 0.0802142 |
| RPL35A | ribosomal protein L35a | 0.0774638 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0757572 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0695457 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0668851 |
| RPLP1 | ribosomal protein, large, P1 | 0.0668474 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.06608 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0624891 |
| CDK13 | cyclin-dependent kinase 13 | 0.0600427 |
| RPS6 | ribosomal protein S6 | 0.0555743 |
| FBXO11 | F-box protein 11 | 0.0548013 |
| RPL37A | ribosomal protein L37a | 0.0547259 |
| CTBP2 | C-terminal binding protein 2 | 0.052887 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0517565 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0514628 |
| ZNF638 | zinc finger protein 638 | 0.0505996 |
| NUP98 | nucleoporin 98kDa | 0.0492204 |
| SQSTM1 | sequestosome 1 | 0.0490798 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0487974 |
| SIK3 | SIK family kinase 3 | 0.0481794 |
| UBAP2 | ubiquitin associated protein 2 | 0.0480578 |
| VIM | vimentin | 0.0478165 |
| RPS8 | ribosomal protein S8 | 0.0477426 |
| UPP1 | uridine phosphorylase 1 | 0.0472682 |
| FBXO17 | F-box protein 17 | 0.0470077 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0462102 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0461611 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0458838 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0453921 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0450703 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0442441 |
| BPTF | bromodomain PHD finger transcription factor | 0.0438431 |
| PTK2 | protein tyrosine kinase 2 | 0.0433534 |
| SEPTIN7 | septin 7 | 0.0430986 |
| FTL | ferritin, light polypeptide | 0.042638 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0425686 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0424902 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0424125 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0422293 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0421685 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0418487 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0417368 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0411005 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0401961 |
| RAD51B | RAD51 paralog B | 0.0398693 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | 0.0393698 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0390079 |
| RPS29 | ribosomal protein S29 | 0.0378352 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0376901 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0374054 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0372684 |
| RPS20 | ribosomal protein S20 | 0.0371968 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0364167 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0356164 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0355239 |
| ZNF780B | zinc finger protein 780B | 0.0352561 |
| FOXO3 | forkhead box O3 | 0.0351285 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0348204 |
| CUX1 | cut-like homeobox 1 | 0.0347483 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0345606 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0343913 |
| PGK1 | phosphoglycerate kinase 1 | 0.0343039 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.034278 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0327597 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0326717 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0320704 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.03143 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | 0.0314152 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0312932 |
| RPL31 | ribosomal protein L31 | 0.0311503 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0307097 |
| ATF6 | activating transcription factor 6 | 0.0305006 |
| THOC2 | THO complex 2 | 0.0304891 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0301253 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0300429 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0298455 |
| HMGA2 | high mobility group AT-hook 2 | 0.0296941 |
| NRDC | nardilysin convertase | 0.0296382 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0291867 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0291775 |
| SATB2 | SATB homeobox 2 | 0.0289637 |
| PHF14 | PHD finger protein 14 | 0.0288803 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0281373 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0280422 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0275027 |
| ZNF146 | zinc finger protein 146 | 0.0273843 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0272436 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0272167 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0268344 |
| MED13 | mediator complex subunit 13 | 0.0268275 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.026739 |
| TBCA | tubulin folding cofactor A | 0.0266733 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0263174 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0263044 |
| RNF216 | ring finger protein 216 | 0.0261808 |
| HM13 | histocompatibility (minor) 13 | 0.0261409 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0260927 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0259986 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.19798 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.142538 |
| EGR1 | early growth response 1 | -0.103113 |
| CD44 | CD44 molecule (Indian blood group) | -0.0923778 |
| ACTN4 | actinin, alpha 4 | -0.0919202 |
| ANLN | anillin, actin binding protein | -0.0854451 |
| FOSL1 | FOS-like antigen 1 | -0.0812324 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0800086 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.075587 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0705872 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0704589 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0680456 |
| TMEM123 | transmembrane protein 123 | -0.0646277 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0624103 |
| VMP1 | vacuole membrane protein 1 | -0.0598103 |
| SMAD3 | SMAD family member 3 | -0.0567059 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0561478 |
| LDHA | lactate dehydrogenase A | -0.0554127 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0547793 |
| CENPF | centromere protein F, 350/400kDa | -0.052785 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0527442 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0525171 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0516563 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0470768 |
| ZNF292 | zinc finger protein 292 | -0.0468895 |
| IPO7 | importin 7 | -0.0461837 |
| TMSB10 | thymosin beta 10 | -0.0452335 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.0445882 |
| UBC | ubiquitin C | -0.0444291 |
| ANXA2 | annexin A2 | -0.0441063 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0437004 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0436784 |
| RPS2 | ribosomal protein S2 | -0.043387 |
| YBX1 | Y box binding protein 1 | -0.0418819 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -0.0418164 |
| TXNRD1 | thioredoxin reductase 1 | -0.0416333 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0412929 |
| CCNL1 | cyclin L1 | -0.0408739 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0408676 |
| ASPH | aspartate beta-hydroxylase | -0.0401287 |
| ACTG1 | actin gamma 1 | -0.0398533 |
| MT2A | metallothionein 2A | -0.0387844 |
| PFN1 | profilin 1 | -0.0384719 |
| SNX14 | sorting nexin 14 | -0.0384633 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | -0.0382343 |
| KLF6 | Kruppel-like factor 6 | -0.0381513 |
| RTN4 | reticulon 4 | -0.0379282 |
| ARRDC3 | arrestin domain containing 3 | -0.03699 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.036772 |
| POTEF | POTE ankyrin domain family, member F | -0.0363271 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0352859 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0352799 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0348752 |
| EIF3K | eukaryotic translation initiation factor 3, subunit K | -0.0348216 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0347952 |
| YBX3 | Y box binding protein 3 | -0.0344588 |
| MYOF | myoferlin | -0.0340633 |
| MCL1 | myeloid cell leukemia 1 | -0.0332755 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0324013 |
| RLIM | ring finger protein, LIM domain interacting | -0.0321167 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0317785 |
| GOLT1A | golgi transport 1A | -0.0311154 |
| PERP | PERP, TP53 apoptosis effector | -0.0310115 |
| RPL32 | ribosomal protein L32 | -0.0309463 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0308289 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0307776 |
| DNMBP | dynamin binding protein | -0.0307654 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0307444 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | -0.030675 |
| TPX2 | TPX2, microtubule-associated | -0.0302426 |
| ZNF217 | zinc finger protein 217 | -0.0302009 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0295736 |
| CD164 | CD164 molecule, sialomucin | -0.0292841 |
| MKI67 | marker of proliferation Ki-67 | -0.0290549 |
| NUP58 | nucleoporin 58 | -0.0288299 |
| CD109 | CD109 molecule | -0.0285359 |
| SBF2 | SET binding factor 2 | -0.0283051 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0282795 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.028239 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0281632 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0280383 |
| CD47 | CD47 molecule | -0.0279897 |
| TPI1 | triosephosphate isomerase 1 | -0.0279114 |
| S100A10 | S100 calcium binding protein A10 | -0.0272574 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0271229 |
| NOP58 | NOP58 ribonucleoprotein | -0.0265545 |
| S100A6 | S100 calcium binding protein A6 | -0.0263749 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0263196 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0262898 |
| CAPRIN1 | cell cycle associated protein 1 | -0.0258607 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0257557 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0257346 |
| MED13L | mediator complex subunit 13-like | -0.0254403 |
| CALR | calreticulin | -0.0253951 |
| SP3 | Sp3 transcription factor | -0.0252084 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0251627 |
| CUL4B | cullin 4B | -0.0250974 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0247333 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.0246724 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0244316 |
