| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lenalidomide (hemihydrate) perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lenalidomide (hemihydrate)_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.13785 |
| RPS6 | ribosomal protein S6 | 0.0768763 |
| MCL1 | myeloid cell leukemia 1 | 0.0761891 |
| HDAC9 | histone deacetylase 9 | 0.0702689 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0604894 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0553691 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0513234 |
| JMJD1C | jumonji domain containing 1C | 0.0506935 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0498403 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0485603 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0480325 |
| DGKI | diacylglycerol kinase, iota | 0.0472069 |
| POTEF | POTE ankyrin domain family, member F | 0.0458365 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0456193 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0427345 |
| SHANK1 | SH3 and multiple ankyrin repeat domains 1 | 0.0427136 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0416964 |
| SET | SET nuclear proto-oncogene | 0.0414305 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0388709 |
| GOLGA4 | golgin A4 | 0.0356026 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0353829 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.035362 |
| RPLP0 | ribosomal protein, large, P0 | 0.0352655 |
| NDRG1 | N-myc downstream regulated 1 | 0.0348553 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0347077 |
| EFL1 | elongation factor like GTPase 1 | 0.0345424 |
| FRMD6 | FERM domain containing 6 | 0.0341458 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0336226 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0331485 |
| PCBP2 | poly(rC) binding protein 2 | 0.0325959 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0320694 |
| GLRX | glutaredoxin (thioltransferase) | 0.0319756 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0318533 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.031192 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0304423 |
| HMGA1 | high mobility group AT-hook 1 | 0.0300935 |
| FOSL1 | FOS-like antigen 1 | 0.0296896 |
| SEC24A | SEC24 family member A | 0.0287742 |
| RPLP1 | ribosomal protein, large, P1 | 0.0284237 |
| UPP1 | uridine phosphorylase 1 | 0.0283348 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0280337 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0273789 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0267735 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0263911 |
| ZNF638 | zinc finger protein 638 | 0.0259305 |
| UBXN4 | UBX domain protein 4 | 0.0259002 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0258557 |
| TRAM1 | translocation associated membrane protein 1 | 0.0248557 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0247316 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0243087 |
| RPS20 | ribosomal protein S20 | 0.0238925 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0237286 |
| TIMM23B | translocase of inner mitochondrial membrane 23 homolog B (yeast) | 0.0234074 |
| PTEN | phosphatase and tensin homolog | 0.0229662 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.022923 |
| USO1 | USO1 vesicle transport factor | 0.0227446 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0225827 |
| TMF1 | TATA element modulatory factor 1 | 0.0225442 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | 0.0222727 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0220786 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.0220237 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0219526 |
| AAK1 | AP2 associated kinase 1 | 0.0216238 |
| AXL | AXL receptor tyrosine kinase | 0.0214578 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0212937 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.021222 |
| TMEM156 | transmembrane protein 156 | 0.0209946 |
| PKM | pyruvate kinase, muscle | 0.0209865 |
| TM4SF19 | transmembrane 4 L six family member 19 | 0.0206522 |
| LYSMD3 | LysM, putative peptidoglycan-binding, domain containing 3 | 0.0204679 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.0204019 |
| KIDINS220 | kinase D-interacting substrate, 220kDa | 0.020323 |
| FAM120A | family with sequence similarity 120A | 0.0202867 |
| SNX13 | sorting nexin 13 | 0.019968 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0199594 |
| RPS8 | ribosomal protein S8 | 0.0198144 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0193667 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | 0.0193431 |
| RASA2 | RAS p21 protein activator 2 | 0.0193296 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0192352 |
| BTBD10 | BTB (POZ) domain containing 10 | 0.0191687 |
| SARS1 | seryl-tRNA synthetase 1 | 0.0191368 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.019085 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0190127 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0190094 |
| ZNF207 | zinc finger protein 207 | 0.0190072 |
| RPS27 | ribosomal protein S27 | 0.0189771 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0188388 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.0187881 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0187649 |
| MTDH | metadherin | 0.018635 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.0185912 |
| PRELID2 | PRELI domain containing 2 | 0.0185703 |
| COPA | coatomer protein complex, subunit alpha | 0.0185027 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase | 0.0184574 |
| CUTC | cutC copper transporter | 0.0183877 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 | 0.0183781 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0183319 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0183012 |
| FN1 | fibronectin 1 | 0.018252 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DLC1 | DLC1 Rho GTPase activating protein | -0.161598 |
| TTR | transthyretin | -0.138279 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.10642 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0896696 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0862587 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0857535 |
| STC1 | stanniocalcin 1 | -0.0806182 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0790989 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0790218 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0720395 |
| MTAP | methylthioadenosine phosphorylase | -0.0709147 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0644058 |
| SP100 | SP100 nuclear antigen | -0.0636875 |
| AHNAK | AHNAK nucleoprotein | -0.0606935 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0543798 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0537152 |
| ZNF438 | zinc finger protein 438 | -0.0515369 |
| RBM39 | RNA binding motif protein 39 | -0.0492001 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0475521 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0462741 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0458797 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0453231 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0450801 |
| TCF12 | transcription factor 12 | -0.0449018 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0432939 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.042277 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | -0.0411278 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0402443 |
| MKI67 | marker of proliferation Ki-67 | -0.0402352 |
| TEX10 | testis expressed 10 | -0.0383858 |
| SBF2 | SET binding factor 2 | -0.0380724 |
| RIGI | RNA sensor RIG-I | -0.0380546 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0378552 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.03711 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0369646 |
| FUS | FUS RNA binding protein | -0.0364424 |
| STK4 | serine/threonine kinase 4 | -0.0363093 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0360954 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.036012 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0355639 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0352334 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0349459 |
| FRMD4A | FERM domain containing 4A | -0.0346033 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0345851 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0345766 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0343656 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0341723 |
| RPL32 | ribosomal protein L32 | -0.0339155 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0338761 |
| ADAR | adenosine deaminase, RNA-specific | -0.0337085 |
| APP | amyloid beta (A4) precursor protein | -0.0336751 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0335757 |
| FLNA | filamin A, alpha | -0.0334116 |
| PTMA | prothymosin, alpha | -0.0332495 |
| ANXA2 | annexin A2 | -0.0328217 |
| DIAPH3 | diaphanous-related formin 3 | -0.03277 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0324256 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0321951 |
| PTK2 | protein tyrosine kinase 2 | -0.0319958 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0317724 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0316186 |
| PCNX4 | pecanex 4 | -0.0311884 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0311746 |
| HLA-C | major histocompatibility complex, class I, C | -0.0309983 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0307092 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | -0.0306199 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.030171 |
| CDK12 | cyclin-dependent kinase 12 | -0.0300037 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0299468 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0298977 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0297331 |
| RPL4 | ribosomal protein L4 | -0.0296811 |
| SMYD3 | SET and MYND domain containing 3 | -0.0293504 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0290614 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0286739 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.028667 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0284885 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0284521 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0283451 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0281169 |
| MATR3 | matrin 3 | -0.0277244 |
| RPL6 | ribosomal protein L6 | -0.0272989 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0272945 |
| HMGA2 | high mobility group AT-hook 2 | -0.0269395 |
| RHEB | Ras homolog enriched in brain | -0.0265813 |
| EWSR1 | EWS RNA-binding protein 1 | -0.0265808 |
| CALR | calreticulin | -0.0262037 |
| BNC2 | basonuclin 2 | -0.0261028 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0260776 |
| STK17A | serine/threonine kinase 17a | -0.0260564 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0258704 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0258501 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0257933 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0257651 |
| WDR1 | WD repeat domain 1 | -0.0255707 |
| EXOC4 | exocyst complex component 4 | -0.0254924 |
| E2F3 | E2F transcription factor 3 | -0.0252466 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0252052 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0251375 |
| FHL2 | four and a half LIM domains 2 | -0.0249884 |
