| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lenalidomide (hemihydrate) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lenalidomide (hemihydrate)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | 0.0892259 |
| STC1 | stanniocalcin 1 | 0.0616698 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0536007 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0513954 |
| HDAC9 | histone deacetylase 9 | 0.0513031 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0459461 |
| ZNF638 | zinc finger protein 638 | 0.0430671 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.041363 |
| RUNX1 | runt-related transcription factor 1 | 0.0397387 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0395223 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0394776 |
| SMAD3 | SMAD family member 3 | 0.0394184 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.037929 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0376364 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0372508 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0363483 |
| ATM | ATM serine/threonine kinase | 0.0358401 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0346588 |
| FHIT | fragile histidine triad | 0.0341423 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0338446 |
| NRP1 | neuropilin 1 | 0.0333853 |
| NAV2 | neuron navigator 2 | 0.0311198 |
| HLA-A | major histocompatibility complex, class I, A | 0.0302374 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0295711 |
| IFI44L | interferon-induced protein 44-like | 0.0290433 |
| SVIL | supervillin | 0.0287011 |
| VEGFA | vascular endothelial growth factor A | 0.0277835 |
| RPS6 | ribosomal protein S6 | 0.0277101 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0276285 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0273484 |
| ATP13A3 | ATPase type 13A3 | 0.0272322 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0270883 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0269149 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0267735 |
| MTSS1 | metastasis suppressor 1 | 0.026557 |
| COL5A3 | collagen, type V, alpha 3 | 0.0255973 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0251928 |
| HMGA2 | high mobility group AT-hook 2 | 0.0250295 |
| PMP22 | peripheral myelin protein 22 | 0.0249597 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0248805 |
| MT2A | metallothionein 2A | 0.0240571 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0237294 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.023618 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0235859 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0235517 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0235347 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0233298 |
| DNAAF9 | dynein axonemal assembly factor 9 | 0.0231724 |
| FAT1 | FAT atypical cadherin 1 | 0.0230868 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.022474 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0221319 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0221068 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0220845 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0220816 |
| EHBP1 | EH domain binding protein 1 | 0.0217621 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0215617 |
| ECE1 | endothelin converting enzyme 1 | 0.0210491 |
| USP34 | ubiquitin specific peptidase 34 | 0.0204834 |
| EXOC6B | exocyst complex component 6B | 0.0202686 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.0202554 |
| MYO9A | myosin IXA | 0.0201023 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0200293 |
| MYOF | myoferlin | 0.019801 |
| SP100 | SP100 nuclear antigen | 0.0196869 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0196484 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0194382 |
| IL6ST | interleukin 6 signal transducer | 0.0192659 |
| EMP1 | epithelial membrane protein 1 | 0.0192614 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | 0.0192336 |
| NAV1 | neuron navigator 1 | 0.0191984 |
| TMF1 | TATA element modulatory factor 1 | 0.0191805 |
| PHF14 | PHD finger protein 14 | 0.0190537 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0190352 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.018934 |
| SMYD3 | SET and MYND domain containing 3 | 0.018776 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0187655 |
| HLA-B | major histocompatibility complex, class I, B | 0.0186838 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0185774 |
| KIAA1217 | KIAA1217 | 0.0185683 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0183725 |
| EVI5 | ecotropic viral integration site 5 | 0.0183531 |
| SON | SON DNA binding protein | 0.0182019 |
| AXL | AXL receptor tyrosine kinase | 0.0181805 |
| MED13 | mediator complex subunit 13 | 0.0181351 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0181087 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | 0.0179848 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0177009 |
| SPG11 | spastic paraplegia 11 (autosomal recessive) | 0.0174914 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0174712 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0173632 |
| GPHN | gephyrin | 0.0173186 |
| ASPH | aspartate beta-hydroxylase | 0.0171645 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.017088 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0170655 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0167928 |
| KIDINS220 | kinase D-interacting substrate, 220kDa | 0.0167134 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0165393 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0165311 |
| GCNA | germ cell nuclear acidic peptidase | 0.0164526 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0164512 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.402913 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.183928 |
| VIM | vimentin | -0.171553 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.142771 |
| NDRG1 | N-myc downstream regulated 1 | -0.0768025 |
| COL1A1 | collagen, type I, alpha 1 | -0.0647769 |
| CDH13 | cadherin 13 | -0.0613866 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0609003 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0558948 |
| TPM4 | tropomyosin 4 | -0.0545277 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0482114 |
| PTMA | prothymosin, alpha | -0.0478747 |
| COL1A2 | collagen, type I, alpha 2 | -0.0470307 |
| PGK1 | phosphoglycerate kinase 1 | -0.0465421 |
| FAM20C | family with sequence similarity 20, member C | -0.0460481 |
| CENPF | centromere protein F, 350/400kDa | -0.0456801 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0451253 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0410593 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0399267 |
| FRMD4A | FERM domain containing 4A | -0.038812 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0376899 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0359673 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.034836 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0345009 |
| GLIS3 | GLIS family zinc finger 3 | -0.0341301 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0337882 |
| TNNC1 | troponin C type 1 (slow) | -0.0336238 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0320015 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0317139 |
| CALU | calumenin | -0.0310903 |
| LDHA | lactate dehydrogenase A | -0.0310015 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0308091 |
| INHBA | inhibin, beta A | -0.0296567 |
| CALR | calreticulin | -0.0295366 |
| THBS1 | thrombospondin 1 | -0.0293011 |
| ZNF292 | zinc finger protein 292 | -0.0286331 |
| IER3 | immediate early response 3 | -0.0284579 |
| FKBP1A | FK506 binding protein 1A, 12kDa | -0.028279 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0276876 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0272417 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0265537 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.0262007 |
| RAB2A | RAB2A, member RAS oncogene family | -0.026116 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0260276 |
| SEC24D | SEC24 family member D | -0.0256511 |
| HDLBP | high density lipoprotein binding protein | -0.0249071 |
| H1-0 | H1.0 linker histone | -0.0246084 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.024539 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.024449 |
| TPM1 | tropomyosin 1 (alpha) | -0.0241719 |
| GOLGA4 | golgin A4 | -0.0238743 |
| POTEF | POTE ankyrin domain family, member F | -0.0233091 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0233037 |
| SMC4 | structural maintenance of chromosomes 4 | -0.023269 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0232611 |
| MKI67 | marker of proliferation Ki-67 | -0.0232388 |
| NCAM1 | neural cell adhesion molecule 1 | -0.02304 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0225321 |
| DIAPH3 | diaphanous-related formin 3 | -0.0223492 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0221019 |
| ANLN | anillin, actin binding protein | -0.0220542 |
| FAM162A | family with sequence similarity 162, member A | -0.0219979 |
| PCBP3 | poly(rC) binding protein 3 | -0.0219781 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.0216274 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.021383 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0209379 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0208942 |
| NREP | neuronal regeneration related protein | -0.0207309 |
| VCAN | versican | -0.0206676 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0206357 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0205979 |
| MORF4L2 | mortality factor 4 like 2 | -0.0205454 |
| RAB1A | RAB1A, member RAS oncogene family | -0.020519 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0204223 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0202884 |
| SBF2 | SET binding factor 2 | -0.0202842 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0202496 |
| TPX2 | TPX2, microtubule-associated | -0.020168 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0199682 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0198396 |
| RPS24 | ribosomal protein S24 | -0.0198203 |
| HECW2 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 | -0.0197857 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0194782 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0194492 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.0194385 |
| TENM4 | teneurin transmembrane protein 4 | -0.0194184 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.0193849 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.019198 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0189083 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.018691 |
| THBS2 | thrombospondin 2 | -0.0183799 |
| QKI | QKI, KH domain containing, RNA binding | -0.0182314 |
| ARF4 | ADP-ribosylation factor 4 | -0.0181906 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0178218 |
| RTN4 | reticulon 4 | -0.0177101 |
| KIF4A | kinesin family member 4A | -0.0176074 |
| CALD1 | caldesmon 1 | -0.0175443 |
| AHNAK | AHNAK nucleoprotein | -0.0174588 |
| LPAR1 | lysophosphatidic acid receptor 1 | -0.0172857 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0171223 |
