| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lenalidomide (hemihydrate) perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lenalidomide (hemihydrate)_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SMOC1 | SPARC related modular calcium binding 1 | 0.0554372 |
| MT2A | metallothionein 2A | 0.0553803 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0544552 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0520583 |
| PDE10A | phosphodiesterase 10A | 0.0472843 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0356487 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0322946 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0312709 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0272545 |
| TMEM255B | transmembrane protein 255B | 0.026786 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0254889 |
| FNDC3A | fibronectin type III domain containing 3A | 0.025312 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0240434 |
| SVIL | supervillin | 0.020982 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0201195 |
| UBE2QL1 | ubiquitin-conjugating enzyme E2Q family-like 1 | 0.0194816 |
| MSN | moesin | 0.0187677 |
| MCL1 | myeloid cell leukemia 1 | 0.0185198 |
| SIK2 | salt-inducible kinase 2 | 0.0183758 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0183385 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0177741 |
| PDE8A | phosphodiesterase 8A | 0.0175914 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0173818 |
| FOXK1 | forkhead box K1 | 0.0173558 |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) | 0.0173189 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0166701 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0165927 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0162618 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0160121 |
| MT1X | metallothionein 1X | 0.0157702 |
| EGFR | epidermal growth factor receptor | 0.0152371 |
| PUM3 | pumilio RNA binding family member 3 | 0.0151954 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.01485 |
| RPS21 | ribosomal protein S21 | 0.0145329 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0145315 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0145055 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0142856 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0141399 |
| WRN | Werner syndrome, RecQ helicase-like | 0.0139438 |
| BMERB1 | bMERB domain containing 1 | 0.0138743 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | 0.0136436 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0136298 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0132431 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0130976 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0129398 |
| FTL | ferritin, light polypeptide | 0.0128909 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0128888 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.0128029 |
| ZCCHC2 | zinc finger, CCHC domain containing 2 | 0.012716 |
| MEIS2 | Meis homeobox 2 | 0.0125633 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 0.0122689 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0119371 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0118201 |
| RPL35A | ribosomal protein L35a | 0.011814 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | 0.0113166 |
| KLHL8 | kelch-like family member 8 | 0.0112604 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0111369 |
| SNX14 | sorting nexin 14 | 0.0111237 |
| CCNH | cyclin H | 0.0110867 |
| WDR25 | WD repeat domain 25 | 0.0109734 |
| NANOS1 | nanos homolog 1 (Drosophila) | 0.0109682 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0109408 |
| SMAD4 | SMAD family member 4 | 0.0107346 |
| PCGF5 | polycomb group ring finger 5 | 0.0107158 |
| RHOQ | ras homolog family member Q | 0.0106353 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0106313 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0106057 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0105547 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0105544 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.0105242 |
| FAM91A1 | family with sequence similarity 91, member A1 | 0.01044 |
| TRPA1 | transient receptor potential cation channel, subfamily A, member 1 | 0.0104357 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0104304 |
| HDAC4 | histone deacetylase 4 | 0.0104145 |
| RPL5 | ribosomal protein L5 | 0.0102831 |
| LEMD3 | LEM domain containing 3 | 0.0102469 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.010234 |
| RNF144A | ring finger protein 144A | 0.0101177 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | 0.00989541 |
| AHR | aryl hydrocarbon receptor | 0.00982451 |
| EFL1 | elongation factor like GTPase 1 | 0.00979324 |
| TNRC6C | trinucleotide repeat containing 6C | 0.00976036 |
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 | 0.00974215 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.00972162 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.00970675 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.00955555 |
| SRBD1 | S1 RNA binding domain 1 | 0.00951458 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.00949769 |
| SSH1 | slingshot protein phosphatase 1 | 0.00942605 |
| GPR107 | G protein-coupled receptor 107 | 0.00933315 |
| YY1AP1 | YY1 associated protein 1 | 0.00924546 |
| ANKRD27 | ankyrin repeat domain 27 (VPS9 domain) | 0.00924213 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 | 0.00922477 |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 | 0.00920204 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.00917467 |
| WLS | wntless Wnt ligand secretion mediator | 0.00903119 |
| SGMS2 | sphingomyelin synthase 2 | 0.0090264 |
| FER | fer (fps/fes related) tyrosine kinase | 0.00901364 |
| MSR1 | macrophage scavenger receptor 1 | 0.0090077 |
| RIGI | RNA sensor RIG-I | 0.00896247 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.133163 |
| PEG10 | paternally expressed 10 | -0.130937 |
| PTMA | prothymosin, alpha | -0.12688 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.109344 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0966211 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0947518 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0946623 |
| GPC6 | glypican 6 | -0.0931176 |
| MAP1B | microtubule-associated protein 1B | -0.0830262 |
| SCG2 | secretogranin II | -0.0749444 |
| CHGB | chromogranin B | -0.0736937 |
| NKAIN2 | Na+/K+ transporting ATPase interacting 2 | -0.073275 |
| CALCA | calcitonin-related polypeptide alpha | -0.0730016 |
| NRG1 | neuregulin 1 | -0.0726516 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0723504 |
| KCND2 | potassium channel, voltage gated Shal related subfamily D, member 2 | -0.0714131 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0709359 |
| KCNB2 | potassium channel, voltage gated Shab related subfamily B, member 2 | -0.0675468 |
| SYT1 | synaptotagmin I | -0.0674724 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0659469 |
| ACTG1 | actin gamma 1 | -0.0644102 |
| ESRRG | estrogen-related receptor gamma | -0.0612907 |
| TMSB4X | thymosin beta 4, X-linked | -0.0543473 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | -0.0542709 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0541189 |
| ENO1 | enolase 1, (alpha) | -0.0531627 |
| SMYD3 | SET and MYND domain containing 3 | -0.0490165 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.0478303 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0467587 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0435855 |
| DTNA | dystrobrevin, alpha | -0.0435758 |
| RIT2 | Ras-like without CAAX 2 | -0.0429499 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0416001 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.040431 |
| H1-0 | H1.0 linker histone | -0.0395652 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0392435 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.036782 |
| NFIA | nuclear factor I/A | -0.0365673 |
| EPHA6 | EPH receptor A6 | -0.0362867 |
| VGF | VGF nerve growth factor inducible | -0.0357611 |
| TCF12 | transcription factor 12 | -0.0357065 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0349551 |
| KCTD8 | potassium channel tetramerization domain containing 8 | -0.0349148 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0345985 |
| KIF26B | kinesin family member 26B | -0.0341786 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0338737 |
| NDRG1 | N-myc downstream regulated 1 | -0.0333296 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0332192 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0330414 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0328735 |
| ADAR | adenosine deaminase, RNA-specific | -0.0326072 |
| CPE | carboxypeptidase E | -0.0325764 |
| MSI2 | musashi RNA-binding protein 2 | -0.0315083 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0310954 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0307972 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0301777 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0299249 |
| CHD7 | chromodomain helicase DNA binding protein 7 | -0.0295699 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0293824 |
| RPL26 | ribosomal protein L26 | -0.0293238 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0293048 |
| NCAM1 | neural cell adhesion molecule 1 | -0.029185 |
| CANX | calnexin | -0.0291422 |
| NELL1 | NEL-like 1 (chicken) | -0.0291382 |
| WWOX | WW domain containing oxidoreductase | -0.0289869 |
| GNAS | GNAS complex locus | -0.0289036 |
| RALYL | RALY RNA binding protein-like | -0.0287949 |
| SSR2 | signal sequence receptor, beta (translocon-associated protein beta) | -0.028774 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.028753 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0287489 |
| POTEF | POTE ankyrin domain family, member F | -0.0285994 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | -0.0284693 |
| YBX1 | Y box binding protein 1 | -0.0281159 |
| SERGEF | secretion regulating guanine nucleotide exchange factor | -0.0280556 |
| S100A9 | S100 calcium binding protein A9 | -0.0276162 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 | -0.0275611 |
| BCL2 | B-cell CLL/lymphoma 2 | -0.0267003 |
| CENPF | centromere protein F, 350/400kDa | -0.0266175 |
| JAM3 | junctional adhesion molecule 3 | -0.0263307 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0261381 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0259062 |
| TPM3 | tropomyosin 3 | -0.0258577 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | -0.0257601 |
| GPC5 | glypican 5 | -0.025612 |
| MTDH | metadherin | -0.0255194 |
| RORA | RAR-related orphan receptor A | -0.0254045 |
| PFN1 | profilin 1 | -0.0253474 |
| UBB | ubiquitin B | -0.0251424 |
| CALR | calreticulin | -0.0250513 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0247064 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.0246867 |
| KLHL29 | kelch-like family member 29 | -0.0246498 |
| MKI67 | marker of proliferation Ki-67 | -0.0246475 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0245823 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0245554 |
| WDR45B | WD repeat domain 45B | -0.0243283 |
| UCMA | upper zone of growth plate and cartilage matrix associated | -0.0239204 |
| SRP72 | signal recognition particle 72kDa | -0.0238708 |
| SLC35F4 | solute carrier family 35, member F4 | -0.0235988 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0233843 |
