| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lenalidomide (hemihydrate) perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lenalidomide (hemihydrate)_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0952618 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0952171 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0687903 |
| CD44 | CD44 molecule (Indian blood group) | 0.0628858 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0611011 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0520342 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.050071 |
| RTN4 | reticulon 4 | 0.0463342 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0453595 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0451962 |
| TXNRD1 | thioredoxin reductase 1 | 0.0437647 |
| PKM | pyruvate kinase, muscle | 0.0432817 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0406072 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0395927 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0392739 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0386862 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0378054 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0372943 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0372934 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0371526 |
| NAV2 | neuron navigator 2 | 0.0362752 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0355229 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0323784 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha | 0.0322909 |
| SETD5 | SET domain containing 5 | 0.0320922 |
| PLSCR1 | phospholipid scramblase 1 | 0.0320672 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0315707 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0314163 |
| RUNX1 | runt-related transcription factor 1 | 0.0314136 |
| ANGPTL4 | angiopoietin-like 4 | 0.0305421 |
| B2M | beta-2-microglobulin | 0.0304246 |
| HDAC9 | histone deacetylase 9 | 0.0303717 |
| BPTF | bromodomain PHD finger transcription factor | 0.0302424 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0297312 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0291563 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0289585 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.028882 |
| CCND1 | cyclin D1 | 0.028793 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0283086 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0281551 |
| MED13 | mediator complex subunit 13 | 0.0280751 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.027655 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0274406 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0273817 |
| SET | SET nuclear proto-oncogene | 0.0271737 |
| CD59 | CD59 molecule, complement regulatory protein | 0.026644 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0260695 |
| CDK6 | cyclin-dependent kinase 6 | 0.0257332 |
| ANXA5 | annexin A5 | 0.0256965 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0255112 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0253374 |
| CENPF | centromere protein F, 350/400kDa | 0.0251155 |
| MSN | moesin | 0.0249993 |
| MYO9A | myosin IXA | 0.0249886 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0248295 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0247605 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 0.0244474 |
| RAB10 | RAB10, member RAS oncogene family | 0.0244081 |
| ITGAV | integrin, alpha V | 0.0242121 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0240693 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0240442 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0238394 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0237437 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0232893 |
| AMOTL1 | angiomotin like 1 | 0.0231844 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0231835 |
| MCL1 | myeloid cell leukemia 1 | 0.0231568 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0230738 |
| CEP128 | centrosomal protein 128kDa | 0.0226637 |
| SCARB2 | scavenger receptor class B, member 2 | 0.0226541 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0225858 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0224615 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0223347 |
| LDHA | lactate dehydrogenase A | 0.0222317 |
| SVIL | supervillin | 0.0221194 |
| MAP1B | microtubule-associated protein 1B | 0.0219494 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0218563 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0218325 |
| DIAPH3 | diaphanous-related formin 3 | 0.0217856 |
| CTSB | cathepsin B | 0.0215513 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0214634 |
| PYGL | phosphorylase, glycogen, liver | 0.0210793 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.0210632 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0207962 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.020477 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.0201103 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0195157 |
| THSD7A | thrombospondin, type I, domain containing 7A | 0.0194359 |
| PGK1 | phosphoglycerate kinase 1 | 0.0194079 |
| DMXL1 | Dmx-like 1 | 0.0193367 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0193058 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | 0.0192092 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0190105 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0189111 |
| VCL | vinculin | 0.0187916 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0184109 |
| ZNF608 | zinc finger protein 608 | 0.0184016 |
| ARF6 | ADP-ribosylation factor 6 | 0.0183942 |
| UBN2 | ubinuclein 2 | 0.0183721 |
| RPL37A | ribosomal protein L37a | 0.0182593 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.272432 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.221044 |
| FRMD4A | FERM domain containing 4A | -0.122904 |
| NLGN1 | neuroligin 1 | -0.0982692 |
| CADM1 | cell adhesion molecule 1 | -0.0665032 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0664109 |
| RAD51B | RAD51 paralog B | -0.0660101 |
| FHIT | fragile histidine triad | -0.0647505 |
| VIM | vimentin | -0.055802 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0552864 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0537596 |
| PTMA | prothymosin, alpha | -0.0525756 |
| LSAMP | limbic system-associated membrane protein | -0.0493517 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | -0.046937 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0446268 |
| MSI2 | musashi RNA-binding protein 2 | -0.0444409 |
| FLNA | filamin A, alpha | -0.0413329 |
| LDLRAD3 | low density lipoprotein receptor class A domain containing 3 | -0.0400898 |
| RPS3 | ribosomal protein S3 | -0.0398279 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0391405 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0385752 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0385447 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0375541 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0370145 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0369649 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0357932 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0340333 |
| SBF2 | SET binding factor 2 | -0.0336391 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0319624 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0317398 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0315285 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0313817 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0300066 |
| TFRC | transferrin receptor | -0.0295789 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0295759 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0295204 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0289909 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0289905 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0289697 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0283563 |
| CALR | calreticulin | -0.0279661 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | -0.0274282 |
| NRN1 | neuritin 1 | -0.0272075 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0267917 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0262678 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0260305 |
| TKT | transketolase | -0.0259797 |
| CTBP2 | C-terminal binding protein 2 | -0.0257339 |
| TMSB10 | thymosin beta 10 | -0.0254449 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | -0.0254116 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0253486 |
| CABIN1 | calcineurin binding protein 1 | -0.0250458 |
| STK4 | serine/threonine kinase 4 | -0.0249884 |
| RBM39 | RNA binding motif protein 39 | -0.0248317 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0242914 |
| HPCAL1 | hippocalcin-like 1 | -0.0242839 |
| SMYD3 | SET and MYND domain containing 3 | -0.0242712 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0242474 |
| PEX5L | peroxisomal biogenesis factor 5-like | -0.0242437 |
| FAM13A | family with sequence similarity 13, member A | -0.0241987 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0241496 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0241275 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -0.0240052 |
| PLEC | plectin | -0.0240019 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0238619 |
| TPD52 | tumor protein D52 | -0.0237174 |
| SEPTIN9 | septin 9 | -0.0236785 |
| NRXN3 | neurexin 3 | -0.0235262 |
| ZNF292 | zinc finger protein 292 | -0.0235165 |
| TOB2 | transducer of ERBB2, 2 | -0.0234855 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0234562 |
| DENND1A | DENN/MADD domain containing 1A | -0.023381 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0233564 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0230268 |
| ACLY | ATP citrate lyase | -0.0229987 |
| TNNC1 | troponin C type 1 (slow) | -0.0229182 |
| NFIA | nuclear factor I/A | -0.0226426 |
| HDLBP | high density lipoprotein binding protein | -0.0226375 |
| USP36 | ubiquitin specific peptidase 36 | -0.0226277 |
| USP3 | ubiquitin specific peptidase 3 | -0.022478 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | -0.0224426 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | -0.022418 |
| COPA | coatomer protein complex, subunit alpha | -0.0223443 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0223419 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.022298 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0218903 |
| HMGA2 | high mobility group AT-hook 2 | -0.0218835 |
| RPL5 | ribosomal protein L5 | -0.021664 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | -0.0216187 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0216137 |
| RPS24 | ribosomal protein S24 | -0.0214767 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.021371 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0212895 |
| CTTN | cortactin | -0.0212072 |
| RYBP | RING1 and YY1 binding protein | -0.021173 |
| FUS | FUS RNA binding protein | -0.0210327 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | -0.0209529 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | -0.0209339 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0206909 |
| FTL | ferritin, light polypeptide | -0.0206448 |
