| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lenalidomide (hemihydrate) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Lenalidomide (hemihydrate)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.125044 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.105005 |
| HDAC9 | histone deacetylase 9 | 0.0897591 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0684019 |
| INTS6 | integrator complex subunit 6 | 0.067431 |
| SQSTM1 | sequestosome 1 | 0.0626443 |
| GPC6 | glypican 6 | 0.0570247 |
| PDE10A | phosphodiesterase 10A | 0.0559723 |
| HMGA2 | high mobility group AT-hook 2 | 0.0546552 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0520624 |
| RND3 | Rho family GTPase 3 | 0.0481578 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0474699 |
| ASPH | aspartate beta-hydroxylase | 0.0451237 |
| CDH13 | cadherin 13 | 0.0441735 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0413948 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0413558 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0412757 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0412589 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0404169 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0400963 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0389244 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0387305 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0361282 |
| LDHA | lactate dehydrogenase A | 0.0359992 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.035218 |
| NDRG1 | N-myc downstream regulated 1 | 0.0350563 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0343612 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0319282 |
| PRELID2 | PRELI domain containing 2 | 0.0317549 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0313279 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0312377 |
| COL5A1 | collagen, type V, alpha 1 | 0.0310644 |
| ADM | adrenomedullin | 0.0305715 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0303255 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0288285 |
| IRS2 | insulin receptor substrate 2 | 0.0284504 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0278745 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0278487 |
| TMEM132D | transmembrane protein 132D | 0.0277798 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0273833 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0267046 |
| NAV2 | neuron navigator 2 | 0.0259792 |
| ARFGEF3 | ARFGEF family member 3 | 0.0250723 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0247095 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0246309 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.024589 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0241607 |
| KYNU | kynureninase | 0.0235257 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.023119 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0230394 |
| CANX | calnexin | 0.0227186 |
| ATXN1 | ataxin 1 | 0.0223475 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.0222606 |
| FNIP1 | folliculin interacting protein 1 | 0.0221235 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0220938 |
| DUSP10 | dual specificity phosphatase 10 | 0.0220851 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0219722 |
| TLE4 | transducin-like enhancer of split 4 | 0.0218726 |
| MYOF | myoferlin | 0.0218652 |
| CTBP2 | C-terminal binding protein 2 | 0.0212946 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0209404 |
| MT2A | metallothionein 2A | 0.0207449 |
| PGM3 | phosphoglucomutase 3 | 0.0206605 |
| TBC1D19 | TBC1 domain family, member 19 | 0.0201156 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0199496 |
| PRKCE | protein kinase C, epsilon | 0.019836 |
| DST | dystonin | 0.0197865 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.019523 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0194968 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 | 0.0193567 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0193359 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0192642 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0186596 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.018483 |
| DTNA | dystrobrevin, alpha | 0.0184509 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0184253 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0182798 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0182449 |
| FMNL2 | formin-like 2 | 0.0180489 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | 0.0178551 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0177459 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.017531 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0174914 |
| ZNF841 | zinc finger protein 841 | 0.0174893 |
| WWOX | WW domain containing oxidoreductase | 0.0174295 |
| EPHA6 | EPH receptor A6 | 0.0173841 |
| SERTAD2 | SERTA domain containing 2 | 0.0173467 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0173234 |
| DMXL1 | Dmx-like 1 | 0.0171007 |
| EFNA5 | ephrin-A5 | 0.0170943 |
| EXOC4 | exocyst complex component 4 | 0.0170793 |
| IER3 | immediate early response 3 | 0.017019 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like | 0.0166991 |
| BRD2 | bromodomain containing 2 | 0.0165986 |
| DENND1A | DENN/MADD domain containing 1A | 0.0165778 |
| FAM107B | family with sequence similarity 107, member B | 0.0165678 |
| AEBP2 | AE binding protein 2 | 0.0163184 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0161446 |
| VAC14 | Vac14 homolog (S. cerevisiae) | 0.0160388 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0160001 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.206076 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.130936 |
| FRMD4A | FERM domain containing 4A | -0.113789 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.108355 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0999373 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.098209 |
| VIM | vimentin | -0.0918803 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0768047 |
| VCL | vinculin | -0.0752243 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0743758 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0713344 |
| RTN4 | reticulon 4 | -0.070679 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.070652 |
| TPM4 | tropomyosin 4 | -0.0655987 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0651906 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0595826 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0552648 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0527705 |
| VMP1 | vacuole membrane protein 1 | -0.0508003 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0502558 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0487305 |
| RPS6 | ribosomal protein S6 | -0.0460781 |
| THBS1 | thrombospondin 1 | -0.0460512 |
| RAI14 | retinoic acid induced 14 | -0.045208 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0450148 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0449781 |
| MSN | moesin | -0.0439907 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0415812 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0415402 |
| MKI67 | marker of proliferation Ki-67 | -0.0406953 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0405322 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0401054 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0376387 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.037004 |
| PTMA | prothymosin, alpha | -0.0363188 |
| SMAD3 | SMAD family member 3 | -0.0362128 |
| PLPP6 | phospholipid phosphatase 6 | -0.0356621 |
| TMSB10 | thymosin beta 10 | -0.0355728 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0339202 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0330272 |
| TMSB4X | thymosin beta 4, X-linked | -0.0322269 |
| TAPBP | TAP binding protein (tapasin) | -0.0321281 |
| ATP13A3 | ATPase type 13A3 | -0.0321031 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0318325 |
| ANXA2 | annexin A2 | -0.031625 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0314957 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0313764 |
| FTL | ferritin, light polypeptide | -0.0312737 |
| SBF2 | SET binding factor 2 | -0.0308871 |
| OSMR | oncostatin M receptor | -0.0303073 |
| RNF24 | ring finger protein 24 | -0.0287932 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0279628 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0277564 |
| PALLD | palladin, cytoskeletal associated protein | -0.0276358 |
| CTSD | cathepsin D | -0.0275622 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0275064 |
| CDCP1 | CUB domain containing protein 1 | -0.027383 |
| YBX1 | Y box binding protein 1 | -0.026257 |
| DENND5A | DENN/MADD domain containing 5A | -0.0249207 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0248661 |
| RBM39 | RNA binding motif protein 39 | -0.0248197 |
| RHOA | ras homolog family member A | -0.0246814 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0244706 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0242916 |
| CLIC4 | chloride intracellular channel 4 | -0.0237117 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0236767 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.023656 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0236015 |
| SERINC3 | serine incorporator 3 | -0.0234436 |
| DIAPH3 | diaphanous-related formin 3 | -0.0231728 |
| TMEM41B | transmembrane protein 41B | -0.0231273 |
| CENPF | centromere protein F, 350/400kDa | -0.0229592 |
| POTEF | POTE ankyrin domain family, member F | -0.0228874 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0225323 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0223653 |
| SLF2 | SMC5-SMC6 complex localization factor 2 | -0.0221596 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0221177 |
| TXNRD1 | thioredoxin reductase 1 | -0.0220665 |
| CCNL1 | cyclin L1 | -0.0219124 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0218836 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0218218 |
| ANLN | anillin, actin binding protein | -0.0215148 |
| PHF21A | PHD finger protein 21A | -0.0214266 |
| KIF4A | kinesin family member 4A | -0.0207293 |
| TMEM123 | transmembrane protein 123 | -0.0207078 |
| MX1 | MX dynamin-like GTPase 1 | -0.020635 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0205716 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0205685 |
| IL6 | interleukin 6 | -0.0205288 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0204999 |
| CD99 | CD99 molecule | -0.0204869 |
| RUNX2 | runt-related transcription factor 2 | -0.0204262 |
| QKI | QKI, KH domain containing, RNA binding | -0.020341 |
| KLF6 | Kruppel-like factor 6 | -0.0203401 |
| VEGFA | vascular endothelial growth factor A | -0.0202157 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.01994 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0198587 |
| TPX2 | TPX2, microtubule-associated | -0.0191677 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0191452 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0191397 |
