| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lenalidomide (hemihydrate) perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lenalidomide (hemihydrate)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.0560696 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0543079 |
| LOXL2 | lysyl oxidase-like 2 | 0.0494244 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0427376 |
| B2M | beta-2-microglobulin | 0.0424798 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0401494 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0383099 |
| CDK13 | cyclin-dependent kinase 13 | 0.0366975 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0348731 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0339788 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.033764 |
| KYNU | kynureninase | 0.0319299 |
| TMEM87A | transmembrane protein 87A | 0.0314547 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.0311417 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0307817 |
| PALLD | palladin, cytoskeletal associated protein | 0.0306027 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0293658 |
| EFNA5 | ephrin-A5 | 0.0293427 |
| MYO9A | myosin IXA | 0.029301 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | 0.0288986 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0284581 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0275865 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0274681 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0270438 |
| FBN1 | fibrillin 1 | 0.0270161 |
| RUNX1 | runt-related transcription factor 1 | 0.0265729 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0265703 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0263241 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0263217 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0262475 |
| DST | dystonin | 0.0261183 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0259644 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0251837 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0250822 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0248383 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0246248 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0245211 |
| RPL35A | ribosomal protein L35a | 0.0244827 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0243263 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0243242 |
| TJP1 | tight junction protein 1 | 0.0242227 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0240281 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0239635 |
| PRELID2 | PRELI domain containing 2 | 0.0237936 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0236436 |
| MYO10 | myosin X | 0.0234433 |
| YEATS2 | YEATS domain containing 2 | 0.0233636 |
| CMIP | c-Maf inducing protein | 0.0233529 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0232792 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0230595 |
| RNF130 | ring finger protein 130 | 0.0230293 |
| RPS20 | ribosomal protein S20 | 0.0229776 |
| GNAS | GNAS complex locus | 0.0228955 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0222623 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0222298 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0221244 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0220246 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0220051 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0218743 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0218592 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.021808 |
| CDH13 | cadherin 13 | 0.0215213 |
| FBXO11 | F-box protein 11 | 0.0214471 |
| ACTG1 | actin gamma 1 | 0.0210901 |
| NKTR | natural killer cell triggering receptor | 0.0210888 |
| PARD3 | par-3 family cell polarity regulator | 0.0209644 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0206804 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0206498 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0205898 |
| PDGFC | platelet derived growth factor C | 0.0205828 |
| LMO7 | LIM domain 7 | 0.0205319 |
| FNIP1 | folliculin interacting protein 1 | 0.0205192 |
| USP25 | ubiquitin specific peptidase 25 | 0.0203665 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0203193 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0202755 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0201953 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0201907 |
| PITPNB | phosphatidylinositol transfer protein, beta | 0.0201459 |
| EXOC4 | exocyst complex component 4 | 0.0201332 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0201245 |
| SQSTM1 | sequestosome 1 | 0.0201093 |
| FBXO16 | F-box protein 16 | 0.0200991 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0200908 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0200458 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0200446 |
| PDS5A | PDS5 cohesin associated factor A | 0.0200369 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0200175 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0198748 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0198302 |
| SRPK2 | SRSF protein kinase 2 | 0.0194914 |
| TXNRD1 | thioredoxin reductase 1 | 0.0194857 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0194709 |
| CEP290 | centrosomal protein 290kDa | 0.0193989 |
| GOLGA3 | golgin A3 | 0.0192293 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.019135 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | 0.0190785 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0190222 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | 0.0188954 |
| MORF4L2 | mortality factor 4 like 2 | 0.0188396 |
| RPL7 | ribosomal protein L7 | 0.0188324 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.271924 |
| FN1 | fibronectin 1 | -0.127418 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0971708 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.095624 |
| POTEF | POTE ankyrin domain family, member F | -0.0824533 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0763032 |
| VIM | vimentin | -0.0742332 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0643704 |
| PKM | pyruvate kinase, muscle | -0.0569515 |
| FTL | ferritin, light polypeptide | -0.0528201 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0503011 |
| COL6A3 | collagen, type VI, alpha 3 | -0.04985 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0472495 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0472245 |
| VEGFA | vascular endothelial growth factor A | -0.0454759 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.045014 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0445319 |
| UBC | ubiquitin C | -0.0442418 |
| NDRG1 | N-myc downstream regulated 1 | -0.0438965 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0429932 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0398118 |
| CALR | calreticulin | -0.0397664 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0391976 |
| PTMA | prothymosin, alpha | -0.0375684 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0360126 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0356043 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.035522 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0351721 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0347566 |
| MAP1B | microtubule-associated protein 1B | -0.0344088 |
| COL1A1 | collagen, type I, alpha 1 | -0.0343306 |
| SDC4 | syndecan 4 | -0.034074 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0334687 |
| TPI1 | triosephosphate isomerase 1 | -0.0326829 |
| C1D | C1D nuclear receptor corepressor | -0.031113 |
| RND3 | Rho family GTPase 3 | -0.0299967 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0299817 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0297919 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0296714 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0294176 |
| CENPF | centromere protein F, 350/400kDa | -0.0294127 |
| WASF2 | WAS protein family, member 2 | -0.0293411 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0293157 |
| MSN | moesin | -0.029304 |
| TAGLN2 | transgelin 2 | -0.0290178 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0289794 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0286155 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0284393 |
| ANXA5 | annexin A5 | -0.0282 |
| HLA-C | major histocompatibility complex, class I, C | -0.027247 |
| TMSB10 | thymosin beta 10 | -0.0272399 |
| ASPH | aspartate beta-hydroxylase | -0.0263579 |
| RHOA | ras homolog family member A | -0.0263201 |
| RBM39 | RNA binding motif protein 39 | -0.0260988 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0257674 |
| CBX5 | chromobox homolog 5 | -0.0255252 |
| S100A10 | S100 calcium binding protein A10 | -0.0253115 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.025155 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0249605 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0243851 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0242422 |
| CUL3 | cullin 3 | -0.0242416 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0238752 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | -0.0238345 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0235155 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0233804 |
| AHCYL1 | adenosylhomocysteinase-like 1 | -0.0231312 |
| INSIG1 | insulin induced gene 1 | -0.0230924 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0229789 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0229513 |
| LAMB1 | laminin, beta 1 | -0.0228429 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0226149 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0224794 |
| S100A6 | S100 calcium binding protein A6 | -0.0224389 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | -0.0223526 |
| SEPTIN7 | septin 7 | -0.0223227 |
| CCDC88A | coiled-coil domain containing 88A | -0.0219205 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.021693 |
| ITGAV | integrin, alpha V | -0.0216261 |
| CCNY | cyclin Y | -0.0215464 |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase | -0.0215313 |
| ACTN1 | actinin, alpha 1 | -0.0212625 |
| NAV1 | neuron navigator 1 | -0.0208768 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0204032 |
| PTN | pleiotrophin | -0.0203559 |
| FAM20C | family with sequence similarity 20, member C | -0.0203328 |
| RORA | RAR-related orphan receptor A | -0.0203103 |
| LMNA | lamin A/C | -0.0202446 |
| TGFB1 | transforming growth factor, beta 1 | -0.0201982 |
| EGR1 | early growth response 1 | -0.0199988 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.0196746 |
| CADM1 | cell adhesion molecule 1 | -0.0194771 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0194308 |
| ZNF395 | zinc finger protein 395 | -0.019303 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0192601 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.019218 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0191664 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0191286 |
| POU2F1 | POU class 2 homeobox 1 | -0.0189445 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0188492 |
