| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Lenalidomide (hemihydrate) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Lenalidomide (hemihydrate)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS6 | ribosomal protein S6 | 0.107481 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0787933 |
| RPLP1 | ribosomal protein, large, P1 | 0.0558128 |
| GOLGA4 | golgin A4 | 0.0525081 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0492644 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0489946 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0482133 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0428483 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.041017 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0404322 |
| RPS12 | ribosomal protein S12 | 0.0398454 |
| RPL37A | ribosomal protein L37a | 0.0392811 |
| WWOX | WW domain containing oxidoreductase | 0.0386791 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0380432 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.035978 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0359551 |
| JMJD1C | jumonji domain containing 1C | 0.0351445 |
| KPNB1 | karyopherin (importin) beta 1 | 0.035131 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0347935 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0340083 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0333013 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0332189 |
| RPL35A | ribosomal protein L35a | 0.0332163 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0324228 |
| SMYD3 | SET and MYND domain containing 3 | 0.0324076 |
| RAD51B | RAD51 paralog B | 0.0322808 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0320823 |
| ZNF638 | zinc finger protein 638 | 0.030958 |
| TMEM41B | transmembrane protein 41B | 0.0291082 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0286863 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0285467 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0284542 |
| MYO1D | myosin ID | 0.0283416 |
| SBF2 | SET binding factor 2 | 0.0280553 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0280443 |
| SLK | STE20-like kinase | 0.0279854 |
| PGK1 | phosphoglycerate kinase 1 | 0.0279145 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0278142 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0278108 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0274073 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0273749 |
| PHIP | pleckstrin homology domain interacting protein | 0.0273464 |
| PRELID2 | PRELI domain containing 2 | 0.0273091 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0272675 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0272383 |
| RPS8 | ribosomal protein S8 | 0.0269482 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0268779 |
| PKM | pyruvate kinase, muscle | 0.0265673 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0264392 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.026263 |
| SET | SET nuclear proto-oncogene | 0.0260719 |
| RPS27 | ribosomal protein S27 | 0.0256455 |
| RPS20 | ribosomal protein S20 | 0.0256236 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0253568 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0252463 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0252226 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0251959 |
| FHIT | fragile histidine triad | 0.0249988 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0249119 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0248208 |
| CERS6 | ceramide synthase 6 | 0.0245868 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0244175 |
| RPS17 | ribosomal protein S17 | 0.0243509 |
| ABHD12 | abhydrolase domain containing 12 | 0.0243402 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.024205 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0238832 |
| NHSL1 | NHS-like 1 | 0.0237294 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0234591 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0233386 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0232975 |
| EXOC6B | exocyst complex component 6B | 0.023256 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.023126 |
| ZNRF2 | zinc and ring finger 2, E3 ubiquitin protein ligase | 0.0230457 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0228857 |
| DSPP | dentin sialophosphoprotein | 0.0228835 |
| GPHN | gephyrin | 0.0226899 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0223363 |
| SRBD1 | S1 RNA binding domain 1 | 0.0222611 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0220665 |
| MSI2 | musashi RNA-binding protein 2 | 0.0220591 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0218336 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0217143 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0216889 |
| PKP4 | plakophilin 4 | 0.021644 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.021608 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0215693 |
| ANO10 | anoctamin 10 | 0.0214694 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0214578 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0214515 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0211198 |
| CUX1 | cut-like homeobox 1 | 0.0207552 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0206905 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0206381 |
| GPATCH8 | G patch domain containing 8 | 0.0205387 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0204932 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0202809 |
| RPS13 | ribosomal protein S13 | 0.020247 |
| SYK | spleen tyrosine kinase | 0.0202458 |
| RPLP0 | ribosomal protein, large, P0 | 0.019995 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0199777 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.104792 |
| EZR | ezrin | -0.104693 |
| KRT8 | keratin 8, type II | -0.0940298 |
| KRT18 | keratin 18, type I | -0.0754702 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0752954 |
| ANXA2 | annexin A2 | -0.0596878 |
| TMSB10 | thymosin beta 10 | -0.0555017 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0540447 |
| RBM39 | RNA binding motif protein 39 | -0.0535537 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0526309 |
| GNAS | GNAS complex locus | -0.0513407 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0510525 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0484808 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0479031 |
| ACTN4 | actinin, alpha 4 | -0.0468704 |
| CST3 | cystatin C | -0.0459043 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0452304 |
| EGR1 | early growth response 1 | -0.0450613 |
| KRT20 | keratin 20, type I | -0.0442399 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0424347 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0408675 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0408546 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0387103 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0374918 |
| NDRG1 | N-myc downstream regulated 1 | -0.0370719 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.0366951 |
| HMGA1 | high mobility group AT-hook 1 | -0.0365962 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0360054 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0359091 |
| EDN1 | endothelin 1 | -0.0338692 |
| POTEF | POTE ankyrin domain family, member F | -0.0336801 |
| UBC | ubiquitin C | -0.0335453 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0333059 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0332987 |
| RYBP | RING1 and YY1 binding protein | -0.033267 |
| INTS6 | integrator complex subunit 6 | -0.0320162 |
| SDC4 | syndecan 4 | -0.0320067 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0318679 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0313473 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0312894 |
| TOP1 | topoisomerase (DNA) I | -0.0312721 |
| IRS2 | insulin receptor substrate 2 | -0.0311596 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0309969 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0308646 |
| FTL | ferritin, light polypeptide | -0.0308014 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0300695 |
| CCNL1 | cyclin L1 | -0.0298669 |
| CCND1 | cyclin D1 | -0.0298515 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0296538 |
| LMNA | lamin A/C | -0.0293716 |
| FLNA | filamin A, alpha | -0.0292272 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0290037 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0282942 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.027742 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0271775 |
| NABP1 | nucleic acid binding protein 1 | -0.0270621 |
| S100A6 | S100 calcium binding protein A6 | -0.0269765 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0264643 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0259004 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0257657 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | -0.0257358 |
| GOLGB1 | golgin B1 | -0.0253504 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0253495 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | -0.0253242 |
| HBP1 | HMG-box transcription factor 1 | -0.0252564 |
| ZNF207 | zinc finger protein 207 | -0.0251587 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0244979 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.0242481 |
| RND3 | Rho family GTPase 3 | -0.0238183 |
| UBE2C | ubiquitin-conjugating enzyme E2C | -0.0234936 |
| VMP1 | vacuole membrane protein 1 | -0.0231953 |
| EWSR1 | EWS RNA-binding protein 1 | -0.0231262 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0230159 |
| EMP1 | epithelial membrane protein 1 | -0.0229785 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0228338 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0227722 |
| S100A10 | S100 calcium binding protein A10 | -0.022753 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0226897 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0222502 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0221719 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0221535 |
| RUNX1 | runt-related transcription factor 1 | -0.0220815 |
| SACK1D | scaffolding CK1 anchoring protein D | -0.0218757 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0218566 |
| CLDN4 | claudin 4 | -0.0216802 |
| FOSL1 | FOS-like antigen 1 | -0.0216237 |
| FAM107B | family with sequence similarity 107, member B | -0.0215681 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.0214007 |
| MXD1 | MAX dimerization protein 1 | -0.0213955 |
| COBL | cordon-bleu WH2 repeat protein | -0.0213171 |
| RRBP1 | ribosome binding protein 1 | -0.0212606 |
| PLK2 | polo-like kinase 2 | -0.0207978 |
| JUP | junction plakoglobin | -0.0206916 |
| S100A11 | S100 calcium binding protein A11 | -0.0206845 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | -0.0206023 |
| H1-0 | H1.0 linker histone | -0.020536 |
| LMO7 | LIM domain 7 | -0.0204415 |
| ZNF217 | zinc finger protein 217 | -0.0204127 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0203432 |
| MYOF | myoferlin | -0.0203246 |
