Leukoplakia Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C1112530
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Genes

194 genes associated with the disease Leukoplakia in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ACD adrenocortical dysplasia homolog (mouse)
ACKR3 atypical chemokine receptor 3
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
APOA1 apolipoprotein A-I
ARHGAP24 Rho GTPase activating protein 24
ATM ATM serine/threonine kinase
AXIN2 axin 2
BAG1 BCL2-associated athanogene
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BDNF brain-derived neurotrophic factor
BRCA1 breast cancer 1, early onset
BSG basigin (Ok blood group)
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CCND1 cyclin D1
CD163 CD163 molecule
CD274 CD274 molecule
CD47 CD47 molecule
CD68 CD68 molecule
CD83 CD83 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8
CHEK2 checkpoint kinase 2
CIB2 calcium and integrin binding family member 2
CKAP4 cytoskeleton-associated protein 4
CKS1B CDC28 protein kinase regulatory subunit 1B
COL4A1 collagen, type IV, alpha 1
COX2
COX5A cytochrome c oxidase subunit Va
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous)
CPOX coproporphyrinogen oxidase
CREB1 cAMP responsive element binding protein 1
CTC1 CTS telomere maintenance complex component 1
CTTN cortactin
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DEFB1 defensin, beta 1
DEFB4A defensin, beta 4A
DEFB4B defensin, beta 4B
DERL3 derlin 3
DES desmin
DKC1 dyskeratosis congenita 1, dyskerin
DLEC1 deleted in lung and esophageal cancer 1
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DUT deoxyuridine triphosphatase
ECM1 extracellular matrix protein 1
ECT2 epithelial cell transforming 2
EGFLAM EGF-like, fibronectin type III and laminin G domains
EGFR epidermal growth factor receptor
EIF5A2 eukaryotic translation initiation factor 5A2
ERBB2 erb-b2 receptor tyrosine kinase 2
ERCC2 excision repair cross-complementation group 2
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FGF2 fibroblast growth factor 2 (basic)
FGF3 fibroblast growth factor 3
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FHIT fragile histidine triad
GAL galanin/GMAP prepropeptide
GFAP glial fibrillary acidic protein
GJB2 gap junction protein, beta 2, 26kDa
GJB6 gap junction protein, beta 6, 30kDa
GPRC5A G protein-coupled receptor, class C, group 5, member A
GSTK1 glutathione S-transferase kappa 1
GSTM1 glutathione S-transferase mu 1
GSTM2 glutathione S-transferase mu 2 (muscle)
GSTM3 glutathione S-transferase mu 3 (brain)
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HOXC13 homeobox C13
HOXC9 homeobox C9
HPGDS hematopoietic prostaglandin D synthase
IL10 interleukin 10
IL17A interleukin 17A
IL1B interleukin 1, beta
IL37 interleukin 37
IL6 interleukin 6
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT10 keratin 10, type I
KRT13 keratin 13, type I
KRT14 keratin 14, type I
KRT16 keratin 16, type I
KRT17 keratin 17, type I
KRT19 keratin 19, type I
KRT4 keratin 4, type II
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
LAMC2 laminin, gamma 2
LCN2 lipocalin 2
LGALS1 lectin, galactoside-binding, soluble, 1
LIG4 ligase IV, DNA, ATP-dependent
LOC102724428 serine/threonine-protein kinase SIK1
LYZ lysozyme
MAL mal, T-cell differentiation protein
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAPKAP1 mitogen-activated protein kinase associated protein 1
MCC mutated in colorectal cancers
MCL1 myeloid cell leukemia 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEFV Mediterranean fever
MET MET proto-oncogene, receptor tyrosine kinase
MFAP5 microfibrillar associated protein 5
MGMT O-6-methylguanine-DNA methyltransferase
MLH1 mutL homolog 1
MMP13 matrix metallopeptidase 13
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MRE11 MRE11 homolog, double strand break repair nuclease
MRPL28 mitochondrial ribosomal protein L28
MSH2 mutS homolog 2
MTUS1 microtubule associated tumor suppressor 1
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NELL2 NEL-like 2 (chicken)
NEUROD1 neuronal differentiation 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NHP2 NHP2 ribonucleoprotein
NOD1 nucleotide-binding oligomerization domain containing 1
NOP10 NOP10 ribonucleoprotein
NOS2 nitric oxide synthase 2, inducible
NOTCH1 notch 1
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NXT1 nuclear transport factor 2-like export factor 1
OGG1 8-oxoguanine DNA glycosylase
ORAOV1 oral cancer overexpressed 1
PABPN1 poly(A) binding protein, nuclear 1
PARN poly(A)-specific ribonuclease
PAX5 paired box 5
PDLIM7 PDZ and LIM domain 7 (enigma)
PDPN podoplanin
PIWIL2 piwi-like RNA-mediated gene silencing 2
POLG2 polymerase (DNA directed), gamma 2, accessory subunit
POLRMT polymerase (RNA) mitochondrial (DNA directed)
PRC1 protein regulator of cytokinesis 1
PRDX1 peroxiredoxin 1
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PROM1 prominin 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RIPK2 receptor-interacting serine-threonine kinase 2
RPE65 retinal pigment epithelium-specific protein 65kDa
RPS6 ribosomal protein S6
RRAS2 related RAS viral (r-ras) oncogene homolog 2
RTEL1 regulator of telomere elongation helicase 1
S100A4 S100 calcium binding protein A4
SAT1 spermidine/spermine N1-acetyltransferase 1
SETBP1 SET binding protein 1
SIK1 salt-inducible kinase 1
SIRPA signal-regulatory protein alpha
SLC12A9 solute carrier family 12, member 9
SLCO6A1 solute carrier organic anion transporter family, member 6A1
SLPI secretory leukocyte peptidase inhibitor
SMAD4 SMAD family member 4
SNAI1 snail family zinc finger 1
SOX2 SRY (sex determining region Y)-box 2
SUB1 SUB1 homolog (S. cerevisiae)
TCHP trichoplein, keratin filament binding
TERT telomerase reverse transcriptase
TFAM transcription factor A, mitochondrial
TGFB1 transforming growth factor, beta 1
TGM3 transglutaminase 3
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TP53 tumor protein p53
TP63 tumor protein p63
TP73 tumor protein p73
TUBB4B tubulin, beta 4B class IVb
USB1 U6 snRNA biogenesis 1
UVRAG UV radiation resistance associated
VEGFA vascular endothelial growth factor A
VIM vimentin
WRAP53 WD repeat containing, antisense to TP53
WWOX WW domain containing oxidoreductase
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1