Leukotriene D4 Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A leukotriene that is (7E,9E,11Z,14Z)-icosa-7,9,11,14-tetraenoic acid substituted by a hydroxy group at position 5 (5S) and a L-cysteinylglycinyl group at position 6 (6R). (Chemical Entities of Biological Interest Ontology, CHEBI_28666)
External Link http://ctdbase.org/detail.go?type=chem&acc=D017998
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Genes

24 genes/proteins interacting with the chemical Leukotriene D4 from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ALOX5 arachidonate 5-lipoxygenase
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CXCL8 chemokine (C-X-C motif) ligand 8
CYSLTR1 cysteinyl leukotriene receptor 1
CYSLTR2 cysteinyl leukotriene receptor 2
FAS Fas cell surface death receptor
GPR17 G protein-coupled receptor 17
ICAM1 intercellular adhesion molecule 1
IL12A interleukin 12A
IL12B interleukin 12B
IL13 interleukin 13
IL5 interleukin 5
IL6 interleukin 6
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MGST1 microsomal glutathione S-transferase 1
MMP9 matrix metallopeptidase 9
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TGFB1 transforming growth factor, beta 1
TNF tumor necrosis factor