| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Levobupivacaine (hydrochloride) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Levobupivacaine (hydrochloride)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0957292 |
| FBN1 | fibrillin 1 | 0.0789088 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0781219 |
| PLAT | plasminogen activator, tissue | 0.0737753 |
| LOXL2 | lysyl oxidase-like 2 | 0.0544562 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0524901 |
| SEPTIN9 | septin 9 | 0.0516235 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0515958 |
| COL3A1 | collagen, type III, alpha 1 | 0.0488834 |
| ATP13A3 | ATPase type 13A3 | 0.0459131 |
| NAV1 | neuron navigator 1 | 0.044692 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0418228 |
| FLNA | filamin A, alpha | 0.0416774 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0412993 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0410252 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0384099 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0380471 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0356076 |
| COL1A2 | collagen, type I, alpha 2 | 0.034894 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0344962 |
| NAV2 | neuron navigator 2 | 0.0341471 |
| AUTS2 | autism susceptibility candidate 2 | 0.0337531 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0322421 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0320259 |
| THBS2 | thrombospondin 2 | 0.0314629 |
| ZNF148 | zinc finger protein 148 | 0.031284 |
| PLEC | plectin | 0.0297143 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0281255 |
| FLNB | filamin B, beta | 0.02777 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0272449 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0271309 |
| GPC6 | glypican 6 | 0.0270445 |
| ARRDC3 | arrestin domain containing 3 | 0.026834 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0261971 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0260621 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0255016 |
| RNF145 | ring finger protein 145 | 0.0253613 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0244051 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0238935 |
| MTSS1 | metastasis suppressor 1 | 0.02374 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0235996 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0233942 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0232864 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0230737 |
| AFDN | afadin, adherens junction formation factor | 0.0229455 |
| APP | amyloid beta (A4) precursor protein | 0.0227963 |
| TPM3 | tropomyosin 3 | 0.0227629 |
| FAM219A | family with sequence similarity 219, member A | 0.0226183 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0223752 |
| IQSEC1 | IQ motif and Sec7 domain 1 | 0.0218942 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0217152 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0215612 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0210801 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0209405 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0208795 |
| SBF2 | SET binding factor 2 | 0.020616 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0204494 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0203644 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0202122 |
| TTC7A | tetratricopeptide repeat domain 7A | 0.0199546 |
| HDLBP | high density lipoprotein binding protein | 0.0198869 |
| RPL3 | ribosomal protein L3 | 0.0198528 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0198362 |
| NGLY1 | N-glycanase 1 | 0.0197989 |
| TMOD1 | tropomodulin 1 | 0.0196245 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0194425 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0193037 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0191217 |
| OPTN | optineurin | 0.0190622 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0189239 |
| LRRC49 | leucine rich repeat containing 49 | 0.0186782 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0185321 |
| UBC | ubiquitin C | 0.0184614 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0183559 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0183512 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0182164 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0181955 |
| RASA2 | RAS p21 protein activator 2 | 0.0179855 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0174453 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0174074 |
| MCL1 | myeloid cell leukemia 1 | 0.0172069 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0171597 |
| FUS | FUS RNA binding protein | 0.0171289 |
| EXOC6B | exocyst complex component 6B | 0.0170769 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0169235 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.0168767 |
| SP3 | Sp3 transcription factor | 0.0166469 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0166283 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0164047 |
| FMNL2 | formin-like 2 | 0.0163864 |
| FAM114A1 | family with sequence similarity 114, member A1 | 0.0163253 |
| ANXA4 | annexin A4 | 0.0161978 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.0161969 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | 0.015996 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0158717 |
| BCL2L1 | BCL2-like 1 | 0.0158679 |
| CDK14 | cyclin-dependent kinase 14 | 0.0157778 |
| MYO9A | myosin IXA | 0.0157774 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0157548 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0157098 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.164378 |
| TMSB10 | thymosin beta 10 | -0.128089 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.119996 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.103172 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.101489 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0986363 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0940152 |
| FN1 | fibronectin 1 | -0.087453 |
| MAP1B | microtubule-associated protein 1B | -0.083501 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0829019 |
| RIGI | RNA sensor RIG-I | -0.0819415 |
| VIM | vimentin | -0.0784122 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0760224 |
| CSTB | cystatin B (stefin B) | -0.0738225 |
| CDH13 | cadherin 13 | -0.0710449 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0710011 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0676063 |
| MT2A | metallothionein 2A | -0.0668722 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0667512 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0666951 |
| ANXA2 | annexin A2 | -0.0627164 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0605601 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0592881 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.058131 |
| LDHA | lactate dehydrogenase A | -0.0570405 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0564012 |
| AHNAK | AHNAK nucleoprotein | -0.0557992 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0550024 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0544776 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0543894 |
| TAGLN2 | transgelin 2 | -0.0535429 |
| POTEF | POTE ankyrin domain family, member F | -0.0526245 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0478324 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0437895 |
| SP100 | SP100 nuclear antigen | -0.0396812 |
| SQSTM1 | sequestosome 1 | -0.0392137 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0377162 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0375634 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0375262 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0374445 |
| ASPH | aspartate beta-hydroxylase | -0.0373009 |
| DCLK2 | doublecortin-like kinase 2 | -0.0369719 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0369557 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0368527 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0362205 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0354805 |
| S100A10 | S100 calcium binding protein A10 | -0.0353358 |
| MYOF | myoferlin | -0.0349551 |
| PKM | pyruvate kinase, muscle | -0.0346372 |
| HLA-B | major histocompatibility complex, class I, B | -0.0339156 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0337685 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0337178 |
| LMNA | lamin A/C | -0.0325216 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0322384 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0311067 |
| SEPTIN7 | septin 7 | -0.0309638 |
| PFN1 | profilin 1 | -0.0306594 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0301177 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0300074 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0297078 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0291108 |
| MT1X | metallothionein 1X | -0.0290229 |
| HDAC9 | histone deacetylase 9 | -0.0282344 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0279578 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.0279194 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0276452 |
| CD44 | CD44 molecule (Indian blood group) | -0.0276157 |
| CANX | calnexin | -0.0273134 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0272519 |
| PGK1 | phosphoglycerate kinase 1 | -0.0271293 |
| COL5A1 | collagen, type V, alpha 1 | -0.0269611 |
| LOX | lysyl oxidase | -0.0267159 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0265849 |
| LRRC17 | leucine rich repeat containing 17 | -0.0265563 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0261778 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0261675 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0261572 |
| SETD5 | SET domain containing 5 | -0.0253703 |
| TRAM2 | translocation associated membrane protein 2 | -0.0253202 |
| PLXNA2 | plexin A2 | -0.0253026 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0252588 |
| CUX1 | cut-like homeobox 1 | -0.0252045 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0250849 |
| BSG | basigin (Ok blood group) | -0.0245641 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.024482 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.024382 |
| TPI1 | triosephosphate isomerase 1 | -0.0242405 |
| EGFR | epidermal growth factor receptor | -0.0238925 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0236838 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0235669 |
| TAOK1 | TAO kinase 1 | -0.0235552 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0234806 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0229245 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0228605 |
| S100A11 | S100 calcium binding protein A11 | -0.0227784 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0227655 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0225059 |
| GNAS | GNAS complex locus | -0.021981 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.0219509 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0219181 |
