| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Levobupivacaine (hydrochloride) perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Levobupivacaine (hydrochloride)_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.105717 |
| AREG | amphiregulin | 0.0919256 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0809916 |
| RACK1 | receptor for activated C kinase 1 | 0.0645583 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0428661 |
| YBX1 | Y box binding protein 1 | 0.0427652 |
| TXNRD1 | thioredoxin reductase 1 | 0.0413433 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0412004 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0375182 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0364683 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0326593 |
| KIF5B | kinesin family member 5B | 0.0326317 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.032548 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0306404 |
| CCNL1 | cyclin L1 | 0.0295724 |
| KLC1 | kinesin light chain 1 | 0.0294811 |
| TPM3 | tropomyosin 3 | 0.0279321 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0270682 |
| RPL3 | ribosomal protein L3 | 0.0269888 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0263603 |
| NUP58 | nucleoporin 58 | 0.0258578 |
| ATP11A | ATPase, class VI, type 11A | 0.0242581 |
| PNN | pinin, desmosome associated protein | 0.023975 |
| GASK1B | golgi associated kinase 1B | 0.0235082 |
| PCM1 | pericentriolar material 1 | 0.0225607 |
| NCKAP1 | NCK-associated protein 1 | 0.0222223 |
| MED13L | mediator complex subunit 13-like | 0.0221573 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0219811 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0219707 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0215926 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0215267 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.021438 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.020994 |
| XPO1 | exportin 1 | 0.0207872 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.0206948 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0204163 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0201348 |
| CENPF | centromere protein F, 350/400kDa | 0.0201216 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0200834 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0191791 |
| COG5 | component of oligomeric golgi complex 5 | 0.0191682 |
| KLHL24 | kelch-like family member 24 | 0.0190491 |
| THOC1 | THO complex 1 | 0.0190116 |
| OXR1 | oxidation resistance 1 | 0.0189889 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0188984 |
| WRN | Werner syndrome, RecQ helicase-like | 0.0187536 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0185715 |
| RPL13A | ribosomal protein L13a | 0.0185513 |
| CDK19 | cyclin-dependent kinase 19 | 0.0181307 |
| YEATS2 | YEATS domain containing 2 | 0.0180123 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0179576 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0179307 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0178723 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0175666 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.017542 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0172609 |
| RBM26 | RNA binding motif protein 26 | 0.0172565 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.017203 |
| SLC49A4 | solute carrier family 49 member 4 | 0.0170613 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.017028 |
| ARRDC3 | arrestin domain containing 3 | 0.0169305 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0169061 |
| EPHA6 | EPH receptor A6 | 0.01678 |
| RASA2 | RAS p21 protein activator 2 | 0.0167393 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0167227 |
| KIF3A | kinesin family member 3A | 0.0167171 |
| GOLGA4 | golgin A4 | 0.0165249 |
| PRPF39 | pre-mRNA processing factor 39 | 0.0164294 |
| SERINC1 | serine incorporator 1 | 0.0163997 |
| TBK1 | TANK-binding kinase 1 | 0.0163841 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0163657 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0163423 |
| PCBP2 | poly(rC) binding protein 2 | 0.0162617 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0161445 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.0160908 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0157467 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0156414 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B | 0.0156224 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.01557 |
| DSPP | dentin sialophosphoprotein | 0.0155316 |
| EDN1 | endothelin 1 | 0.0155084 |
| CAND1 | cullin-associated and neddylation-dissociated 1 | 0.0154745 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0153453 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0151826 |
| CEP95 | centrosomal protein 95kDa | 0.0151741 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0150993 |
| WDR43 | WD repeat domain 43 | 0.0150496 |
| CPOX | coproporphyrinogen oxidase | 0.0149979 |
| SET | SET nuclear proto-oncogene | 0.0149442 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0147001 |
| STRN | striatin, calmodulin binding protein | 0.01469 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0146347 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0145482 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0144295 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.0143352 |
| FLNA | filamin A, alpha | 0.0142891 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0141636 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0141602 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0141551 |
| TPR | translocated promoter region, nuclear basket protein | 0.0141037 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.198353 |
| NLGN1 | neuroligin 1 | -0.183656 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.17794 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.124183 |
| TMSB10 | thymosin beta 10 | -0.118175 |
| HMGA2 | high mobility group AT-hook 2 | -0.0895184 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0766095 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0756576 |
| ACTG1 | actin gamma 1 | -0.0738936 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0719026 |
| MMP12 | matrix metallopeptidase 12 | -0.0646566 |
| PCDH7 | protocadherin 7 | -0.0639379 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0577545 |
| ZNF804A | zinc finger protein 804A | -0.0551879 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.054635 |
| VIM | vimentin | -0.0539376 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0494995 |
| RASAL2 | RAS protein activator like 2 | -0.0482042 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0480695 |
| NHSL1 | NHS-like 1 | -0.0473694 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0467666 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0463856 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0456381 |
| EHBP1 | EH domain binding protein 1 | -0.0452656 |
| PTMA | prothymosin, alpha | -0.0443321 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0432637 |
| SLC38A2 | solute carrier family 38, member 2 | -0.043082 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0421374 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0383448 |
| YAP1 | Yes-associated protein 1 | -0.037773 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0377076 |
| JMJD1C | jumonji domain containing 1C | -0.0369898 |
| CANX | calnexin | -0.0362776 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0360108 |
| EGR1 | early growth response 1 | -0.0356583 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0353475 |
| DST | dystonin | -0.035092 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0342872 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0336626 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.032301 |
| MAP1B | microtubule-associated protein 1B | -0.0315626 |
| CUX1 | cut-like homeobox 1 | -0.0314972 |
| ADIPOR2 | adiponectin receptor 2 | -0.031474 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0312786 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0308799 |
| S100A10 | S100 calcium binding protein A10 | -0.0308264 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0308021 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0303023 |
| INTS6 | integrator complex subunit 6 | -0.0300778 |
| SYT1 | synaptotagmin I | -0.0299775 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0298817 |
| R3HDM2 | R3H domain containing 2 | -0.0294553 |
| FTL | ferritin, light polypeptide | -0.0292745 |
| L3MBTL4 | l(3)mbt-like 4 (Drosophila) | -0.0283826 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0283552 |
| ASPH | aspartate beta-hydroxylase | -0.0279217 |
| NAV3 | neuron navigator 3 | -0.027887 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0276935 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0272793 |
| CCND1 | cyclin D1 | -0.0270586 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0262795 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0259992 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0259648 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0257155 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0257024 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0254216 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0253618 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0246514 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0245692 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0242603 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0242278 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0241778 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0240822 |
| DTNA | dystrobrevin, alpha | -0.0239988 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0237357 |
| TPM4 | tropomyosin 4 | -0.0236347 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0236054 |
| NABP1 | nucleic acid binding protein 1 | -0.0231418 |
| HMGA1 | high mobility group AT-hook 1 | -0.0230823 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0230502 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0226513 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) | -0.0224118 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0222411 |
| EDARADD | EDAR-associated death domain | -0.0221985 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0220708 |
| TENM3 | teneurin transmembrane protein 3 | -0.0219921 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0219187 |
| SETX | senataxin | -0.0216953 |
| RPS6 | ribosomal protein S6 | -0.021447 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.021407 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0212397 |
| RPS8 | ribosomal protein S8 | -0.0209792 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0209408 |
| H3-3B | H3.3 histone B | -0.0204547 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0204387 |
| DIAPH2 | diaphanous-related formin 2 | -0.0203343 |
| TUBA1B | tubulin, alpha 1b | -0.0202375 |
| CALR | calreticulin | -0.0198581 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0198537 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.019785 |
