| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Levobupivacaine (hydrochloride) perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Levobupivacaine (hydrochloride)_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAV2 | neuron navigator 2 | 0.0511304 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0485599 |
| FLNA | filamin A, alpha | 0.0484297 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0476967 |
| SMAD3 | SMAD family member 3 | 0.0452731 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0446527 |
| MSN | moesin | 0.0420234 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0406032 |
| NUP58 | nucleoporin 58 | 0.0396235 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0363489 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0363042 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0346067 |
| PLEC | plectin | 0.034562 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0324363 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0311374 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0308896 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0307904 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0295883 |
| RPL3 | ribosomal protein L3 | 0.0293133 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.029289 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0280488 |
| RACK1 | receptor for activated C kinase 1 | 0.0280421 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0274906 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | 0.024139 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0240995 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0240662 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0232199 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0230661 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0219332 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0218675 |
| CMIP | c-Maf inducing protein | 0.0218015 |
| MCL1 | myeloid cell leukemia 1 | 0.020322 |
| TBK1 | TANK-binding kinase 1 | 0.0202737 |
| HDGF | hepatoma-derived growth factor | 0.0201177 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0200518 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0196315 |
| MYO1B | myosin IB | 0.0192743 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0191601 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0190353 |
| PCBP2 | poly(rC) binding protein 2 | 0.0188166 |
| CCNL1 | cyclin L1 | 0.0184239 |
| TPM3 | tropomyosin 3 | 0.0180724 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0179869 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0177692 |
| WDR43 | WD repeat domain 43 | 0.0177516 |
| SMYD3 | SET and MYND domain containing 3 | 0.0177447 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | 0.0175481 |
| PDZD8 | PDZ domain containing 8 | 0.0175392 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0169324 |
| PCM1 | pericentriolar material 1 | 0.0168606 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0167494 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0166666 |
| ITSN2 | intersectin 2 | 0.0164525 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0164311 |
| YEATS2 | YEATS domain containing 2 | 0.0164145 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0162966 |
| BCL2L1 | BCL2-like 1 | 0.0162825 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0161385 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0160121 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0156666 |
| PRPF39 | pre-mRNA processing factor 39 | 0.0155361 |
| SP3 | Sp3 transcription factor | 0.0153968 |
| CD44 | CD44 molecule (Indian blood group) | 0.0153365 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0152767 |
| FNBP4 | formin binding protein 4 | 0.0151893 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0151367 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0150704 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0150468 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0149841 |
| CEP135 | centrosomal protein 135kDa | 0.0147639 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0146963 |
| XPO1 | exportin 1 | 0.0146395 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | 0.0146175 |
| CASC3 | cancer susceptibility candidate 3 | 0.0145669 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0145441 |
| LTBP4 | latent transforming growth factor beta binding protein 4 | 0.0145323 |
| CENPF | centromere protein F, 350/400kDa | 0.0144472 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0142842 |
| PRELID2 | PRELI domain containing 2 | 0.0142744 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 | 0.0141683 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0140773 |
| ECT2 | epithelial cell transforming 2 | 0.0139714 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0137331 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0137294 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0136894 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0136528 |
| RLIM | ring finger protein, LIM domain interacting | 0.0136314 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0135921 |
| VEGFA | vascular endothelial growth factor A | 0.0135755 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0134672 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0134184 |
| NIPA1 | non imprinted in Prader-Willi/Angelman syndrome 1 | 0.0134132 |
| CUL3 | cullin 3 | 0.0131733 |
| HAPSTR1 | HUWE1 associated protein modifying stress responses | 0.0131417 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0131382 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0130668 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0129732 |
| BLTP3B | bridge-like lipid transfer protein family member 3B | 0.0129653 |
| CSRP1 | cysteine and glycine-rich protein 1 | 0.0129624 |
| PDE8A | phosphodiesterase 8A | 0.0129412 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.308243 |
| TMSB10 | thymosin beta 10 | -0.231859 |
| FTL | ferritin, light polypeptide | -0.19871 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.179543 |
| ACTG1 | actin gamma 1 | -0.154448 |
| MT2A | metallothionein 2A | -0.12567 |
| VIM | vimentin | -0.122128 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.11454 |
| ANXA2 | annexin A2 | -0.112757 |
| RPS19 | ribosomal protein S19 | -0.111675 |
| RPLP1 | ribosomal protein, large, P1 | -0.102278 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.101104 |
| RPS6 | ribosomal protein S6 | -0.0986141 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0978927 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0847444 |
| KRT81 | keratin 81, type II | -0.0822972 |
| RPS16 | ribosomal protein S16 | -0.081004 |
| PTMA | prothymosin, alpha | -0.078015 |
| RPS24 | ribosomal protein S24 | -0.0777046 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0753708 |
| MT1X | metallothionein 1X | -0.0735748 |
| S100A6 | S100 calcium binding protein A6 | -0.072875 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0658612 |
| S100A10 | S100 calcium binding protein A10 | -0.0592151 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0577814 |
| RPS27A | ribosomal protein S27a | -0.0573405 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0563074 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0557709 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0543885 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0541448 |
| RPL12 | ribosomal protein L12 | -0.0540475 |
| CA12 | carbonic anhydrase XII | -0.0538213 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0538099 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0510796 |
| EFNA5 | ephrin-A5 | -0.050936 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0496929 |
| RPL19 | ribosomal protein L19 | -0.0488693 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0480482 |
| RPS5 | ribosomal protein S5 | -0.0464 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0461349 |
| RPS3 | ribosomal protein S3 | -0.0457568 |
| RPLP0 | ribosomal protein, large, P0 | -0.0450765 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0448654 |
| RPL31 | ribosomal protein L31 | -0.0448177 |
| RPL26 | ribosomal protein L26 | -0.0444582 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0441458 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0441056 |
| STC1 | stanniocalcin 1 | -0.0439962 |
| EHBP1 | EH domain binding protein 1 | -0.0437024 |
| RPL28 | ribosomal protein L28 | -0.0430626 |
| RPS8 | ribosomal protein S8 | -0.0419534 |
| RPL35A | ribosomal protein L35a | -0.0414857 |
| RPL37A | ribosomal protein L37a | -0.0410022 |
| RPS11 | ribosomal protein S11 | -0.0409998 |
| RPL23 | ribosomal protein L23 | -0.0407412 |
| KYNU | kynureninase | -0.0401943 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0396412 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0388912 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0383844 |
| NDRG1 | N-myc downstream regulated 1 | -0.038174 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0377436 |
| RPL34 | ribosomal protein L34 | -0.0366011 |
| IER3 | immediate early response 3 | -0.0364808 |
| RPS21 | ribosomal protein S21 | -0.0358781 |
| RPLP2 | ribosomal protein, large, P2 | -0.0355538 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0355536 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0353474 |
| RPS29 | ribosomal protein S29 | -0.0353466 |
| RPL13A | ribosomal protein L13a | -0.0352877 |
| ASPH | aspartate beta-hydroxylase | -0.0352248 |
| RPL8 | ribosomal protein L8 | -0.0351238 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.035111 |
| RPL7A | ribosomal protein L7a | -0.0347947 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0347367 |
| RPL38 | ribosomal protein L38 | -0.0346685 |
| RPS13 | ribosomal protein S13 | -0.0342247 |
| RPL18 | ribosomal protein L18 | -0.0335985 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0333661 |
| KRT7 | keratin 7, type II | -0.0325081 |
| PGK1 | phosphoglycerate kinase 1 | -0.0319232 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0318259 |
| RPS23 | ribosomal protein S23 | -0.0317338 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0313732 |
| RPL32 | ribosomal protein L32 | -0.0312228 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0312081 |
| TKT | transketolase | -0.0311389 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0310979 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0310484 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0304658 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0297037 |
| SP100 | SP100 nuclear antigen | -0.0295326 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0294851 |
| PKM | pyruvate kinase, muscle | -0.0294597 |
| EPAS1 | endothelial PAS domain protein 1 | -0.029387 |
| KLF6 | Kruppel-like factor 6 | -0.0288724 |
| RAI14 | retinoic acid induced 14 | -0.028654 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0283332 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0282323 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0272553 |
| RPL27A | ribosomal protein L27a | -0.0272499 |
