| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Levobupivacaine (hydrochloride) perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Levobupivacaine (hydrochloride)_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SEPTIN11 | septin 11 | 0.0812892 |
| TMSB4X | thymosin beta 4, X-linked | 0.0748306 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0514996 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0503804 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0497045 |
| MEOX2 | mesenchyme homeobox 2 | 0.0492459 |
| SMYD3 | SET and MYND domain containing 3 | 0.0482966 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0468775 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0468461 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0462065 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0448557 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0422679 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0422248 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0412747 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0411497 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0391016 |
| TPM4 | tropomyosin 4 | 0.0376889 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.037203 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0351512 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0350859 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0347847 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0340379 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0336397 |
| USP34 | ubiquitin specific peptidase 34 | 0.0332451 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.0330303 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0324308 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0322552 |
| SOBP | sine oculis binding protein homolog (Drosophila) | 0.0315224 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0315128 |
| MGP | matrix Gla protein | 0.0314572 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0308466 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0305343 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0304751 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0302054 |
| SIK3 | SIK family kinase 3 | 0.0298592 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0297547 |
| TXNRD1 | thioredoxin reductase 1 | 0.0295566 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.02907 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0288729 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0284292 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0280983 |
| SHROOM3 | shroom family member 3 | 0.0279761 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.0279334 |
| GTF2I | general transcription factor IIi | 0.0277657 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 0.0275446 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0274546 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | 0.0271581 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0271106 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.026719 |
| EGFR | epidermal growth factor receptor | 0.0267038 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0266639 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0264277 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0263842 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0258812 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0255926 |
| NBEA | neurobeachin | 0.025465 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0251725 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0248421 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0247756 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0247077 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.024563 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | 0.024504 |
| MYO1B | myosin IB | 0.0242393 |
| RBM26 | RNA binding motif protein 26 | 0.0237094 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | 0.0231789 |
| RHOA | ras homolog family member A | 0.0230125 |
| PRELID2 | PRELI domain containing 2 | 0.0229459 |
| USP22 | ubiquitin specific peptidase 22 | 0.0229389 |
| DBN1 | drebrin 1 | 0.0228936 |
| CSNK1G3 | casein kinase 1, gamma 3 | 0.0226627 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0225642 |
| EVI5 | ecotropic viral integration site 5 | 0.0224356 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0223026 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0222836 |
| COL1A2 | collagen, type I, alpha 2 | 0.0222621 |
| CEP250 | centrosomal protein 250kDa | 0.0222606 |
| RPS15A | ribosomal protein S15a | 0.0222452 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.0220993 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.022094 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0220643 |
| TOR1AIP2 | torsin A interacting protein 2 | 0.0217752 |
| ZNF37A | zinc finger protein 37A | 0.0216459 |
| FBN1 | fibrillin 1 | 0.0215842 |
| KIAA1549 | KIAA1549 | 0.0215452 |
| PLEC | plectin | 0.0215353 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0215066 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.021479 |
| ATG5 | autophagy related 5 | 0.0214715 |
| PCM1 | pericentriolar material 1 | 0.0213961 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0213725 |
| ZNF106 | zinc finger protein 106 | 0.0212369 |
| UBC | ubiquitin C | 0.0212043 |
| STX18 | syntaxin 18 | 0.0211452 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.0210193 |
| AHNAK | AHNAK nucleoprotein | 0.0210033 |
| GOLM2 | golgi membrane protein 2 | 0.0208519 |
| MTAP | methylthioadenosine phosphorylase | 0.0208185 |
| UBQLN1 | ubiquilin 1 | 0.020748 |
| CANX | calnexin | 0.0207449 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0207382 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.117863 |
| CADM2 | cell adhesion molecule 2 | -0.0794716 |
| RPS6 | ribosomal protein S6 | -0.0728683 |
| JMJD1C | jumonji domain containing 1C | -0.0676352 |
| RPLP1 | ribosomal protein, large, P1 | -0.0621116 |
| MT2A | metallothionein 2A | -0.0613747 |
| VIM | vimentin | -0.0586309 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0503974 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0502106 |
| RPS19 | ribosomal protein S19 | -0.0466772 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0458185 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0437967 |
| IER3 | immediate early response 3 | -0.0414424 |
| PHF3 | PHD finger protein 3 | -0.0404832 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.037839 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0359644 |
| RPL35A | ribosomal protein L35a | -0.0358268 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0357128 |
| RPL12 | ribosomal protein L12 | -0.0354153 |
| PKM | pyruvate kinase, muscle | -0.0352969 |
| RPL32 | ribosomal protein L32 | -0.0349843 |
| RPL37A | ribosomal protein L37a | -0.0346307 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0343347 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0341528 |
| SBF2 | SET binding factor 2 | -0.034049 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0333293 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0326328 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0321611 |
| RPS24 | ribosomal protein S24 | -0.0320286 |
| RPS8 | ribosomal protein S8 | -0.0319646 |
| FNIP1 | folliculin interacting protein 1 | -0.0313519 |
| RPLP2 | ribosomal protein, large, P2 | -0.0311748 |
| RPL34 | ribosomal protein L34 | -0.030464 |
| PHIP | pleckstrin homology domain interacting protein | -0.0299624 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0298415 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0298233 |
| CREBRF | CREB3 regulatory factor | -0.0292242 |
| RYBP | RING1 and YY1 binding protein | -0.0292203 |
| IGF2 | insulin-like growth factor 2 | -0.0291722 |
| FTL | ferritin, light polypeptide | -0.029121 |
| ZNF292 | zinc finger protein 292 | -0.0290324 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0286558 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0285086 |
| TMSB10 | thymosin beta 10 | -0.0277995 |
| RPL18 | ribosomal protein L18 | -0.0270907 |
| GOLGA4 | golgin A4 | -0.0266133 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0265438 |
| NKTR | natural killer cell triggering receptor | -0.0264116 |
| RPS29 | ribosomal protein S29 | -0.0261872 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0261095 |
| TULP4 | tubby like protein 4 | -0.0260527 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0258857 |
| SMAD3 | SMAD family member 3 | -0.0253031 |
| MED13L | mediator complex subunit 13-like | -0.0250915 |
| UPF3B | UPF3 regulator of nonsense transcripts homolog B (yeast) | -0.0244636 |
| RPS14 | ribosomal protein S14 | -0.0242999 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0242868 |
| PPIL4 | peptidylprolyl isomerase (cyclophilin)-like 4 | -0.0242427 |
| NCOA2 | nuclear receptor coactivator 2 | -0.0241276 |
| RPL23 | ribosomal protein L23 | -0.0240039 |
| ZNF395 | zinc finger protein 395 | -0.0237715 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0236982 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0236927 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0236731 |
| FAM162A | family with sequence similarity 162, member A | -0.0234376 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0234336 |
| UBE3A | ubiquitin protein ligase E3A | -0.0233839 |
| DEK | DEK proto-oncogene | -0.0233753 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.0233598 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0230697 |
| FAM13A | family with sequence similarity 13, member A | -0.0227713 |
| RBM25 | RNA binding motif protein 25 | -0.0227611 |
| NUCB2 | nucleobindin 2 | -0.022747 |
| POU2F1 | POU class 2 homeobox 1 | -0.0226861 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0226329 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.022443 |
| OGA | O-GlcNAcase | -0.0221077 |
| SQSTM1 | sequestosome 1 | -0.0220888 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | -0.0220346 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | -0.0218837 |
| S100A9 | S100 calcium binding protein A9 | -0.0217748 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0216442 |
| HMGA1 | high mobility group AT-hook 1 | -0.021523 |
| MED13 | mediator complex subunit 13 | -0.0213332 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0211565 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0211085 |
| PPP4R2 | protein phosphatase 4, regulatory subunit 2 | -0.0209759 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0209635 |
| GNG2 | guanine nucleotide binding protein (G protein), gamma 2 | -0.0208697 |
| CREBBP | CREB binding protein | -0.0208499 |
| RPS3 | ribosomal protein S3 | -0.0207201 |
| KDM3B | lysine (K)-specific demethylase 3B | -0.020661 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 | -0.020647 |
| SGO2 | shugoshin 2 | -0.0206403 |
| CDK19 | cyclin-dependent kinase 19 | -0.0205714 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0204874 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0203939 |
| ATP6V1H | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | -0.0203766 |
| RPS10 | ribosomal protein S10 | -0.0203714 |
| SMAP1 | small ArfGAP 1 | -0.0202508 |