| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Levobupivacaine (hydrochloride) perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Levobupivacaine (hydrochloride)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL23 | ribosomal protein L23 | 0.184371 |
| LASP1 | LIM and SH3 protein 1 | 0.101786 |
| CEP250 | centrosomal protein 250kDa | 0.0855662 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0757947 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0745891 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0659816 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | 0.0606852 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0585081 |
| ACACA | acetyl-CoA carboxylase alpha | 0.0546696 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0538851 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0525661 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0486425 |
| RACK1 | receptor for activated C kinase 1 | 0.0468283 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.0465274 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0430866 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.04037 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0398605 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0387439 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.0364089 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0345094 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0343419 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0340719 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0337986 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0319494 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0318696 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0308234 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 | 0.0303202 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0303152 |
| ENAH | enabled homolog (Drosophila) | 0.0297043 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0292484 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0290326 |
| FASN | fatty acid synthase | 0.0288881 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | 0.0282797 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.027813 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0273241 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0271625 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0270032 |
| NCOA6 | nuclear receptor coactivator 6 | 0.0263882 |
| SRCIN1 | SRC kinase signaling inhibitor 1 | 0.0261673 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.025971 |
| PLEC | plectin | 0.0255548 |
| ENO1 | enolase 1, (alpha) | 0.0251577 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0251182 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0246759 |
| VMP1 | vacuole membrane protein 1 | 0.0245452 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0240658 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0240188 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0240096 |
| DUSP4 | dual specificity phosphatase 4 | 0.0239815 |
| DENND1A | DENN/MADD domain containing 1A | 0.0236533 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0236401 |
| FLNA | filamin A, alpha | 0.0234684 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0234042 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0230512 |
| CD24 | CD24 molecule | 0.0228765 |
| RAD51B | RAD51 paralog B | 0.022792 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0224858 |
| TPM3 | tropomyosin 3 | 0.0224219 |
| ORMDL3 | ORMDL sphingolipid biosynthesis regulator 3 | 0.0223999 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0222994 |
| ZNF652 | zinc finger protein 652 | 0.0221618 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0220996 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0219965 |
| NCKAP1 | NCK-associated protein 1 | 0.02167 |
| DSPP | dentin sialophosphoprotein | 0.0213198 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0212193 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0211222 |
| RNF213 | ring finger protein 213 | 0.0208243 |
| HDLBP | high density lipoprotein binding protein | 0.020757 |
| MSI2 | musashi RNA-binding protein 2 | 0.0202129 |
| YBX1 | Y box binding protein 1 | 0.019909 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.019694 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0195096 |
| HS6ST2 | heparan sulfate 6-O-sulfotransferase 2 | 0.0194178 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | 0.0190675 |
| GSE1 | Gse1 coiled-coil protein | 0.0188348 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.018568 |
| RPL3 | ribosomal protein L3 | 0.0185454 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0183677 |
| LRRC59 | leucine rich repeat containing 59 | 0.018245 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0181676 |
| KIF1A | kinesin family member 1A | 0.018156 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0180422 |
| PGK1 | phosphoglycerate kinase 1 | 0.0178504 |
| KRT7 | keratin 7, type II | 0.0177755 |
| MACROD1 | MACRO domain containing 1 | 0.0175347 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0175276 |
| SEPTIN11 | septin 11 | 0.0175148 |
| CCNL1 | cyclin L1 | 0.017386 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | 0.0172235 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0171913 |
| PLEKHA7 | pleckstrin homology domain containing, family A member 7 | 0.0171666 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.01716 |
| NFIA | nuclear factor I/A | 0.0171026 |
| TNRC18 | trinucleotide repeat containing 18 | 0.016877 |
| CUX1 | cut-like homeobox 1 | 0.0167675 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0165545 |
| FHIT | fragile histidine triad | 0.0165408 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0164933 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0164611 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.0841008 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0782045 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0721783 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0677368 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0534154 |
| S100A8 | S100 calcium binding protein A8 | -0.0520454 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0484688 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0475082 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0459134 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0432831 |
| S100A9 | S100 calcium binding protein A9 | -0.0428751 |
| RPL19 | ribosomal protein L19 | -0.0417372 |
| ACTG1 | actin gamma 1 | -0.0412189 |
| CLTC | clathrin, heavy chain (Hc) | -0.0410158 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0403981 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0382557 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0372761 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0371332 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0334031 |
| TXNRD1 | thioredoxin reductase 1 | -0.0332726 |
| TMEM165 | transmembrane protein 165 | -0.0325344 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0312983 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0309724 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0295212 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0294887 |
| DUSP16 | dual specificity phosphatase 16 | -0.0294867 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0292761 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0291301 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0283093 |
| CCNI | cyclin I | -0.0262832 |
| ANKRD12 | ankyrin repeat domain 12 | -0.025777 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0255676 |
| TOM1L1 | target of myb1 (chicken)-like 1 | -0.0254341 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | -0.0253017 |
| CDH15 | cadherin 15, type 1, M-cadherin (myotubule) | -0.0248151 |
| PFDN4 | prefoldin subunit 4 | -0.0248022 |
| SDC4 | syndecan 4 | -0.0240535 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0239295 |
| PSMB3 | proteasome (prosome, macropain) subunit, beta type, 3 | -0.0239169 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.0230103 |
| S100A7 | S100 calcium binding protein A7 | -0.0227577 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0222774 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0221028 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0210392 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0209907 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | -0.0209018 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0208979 |
| EGFR | epidermal growth factor receptor | -0.0203247 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | -0.0200911 |
| RPS2 | ribosomal protein S2 | -0.0200072 |
| FNBP1 | formin binding protein 1 | -0.0199171 |
| DUSP6 | dual specificity phosphatase 6 | -0.0197236 |
| DSG2 | desmoglein 2 | -0.0192647 |
| PTMA | prothymosin, alpha | -0.0191965 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.0191085 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0188656 |
| UBXN4 | UBX domain protein 4 | -0.018856 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0187143 |
| KIAA1217 | KIAA1217 | -0.0183409 |
| AREG | amphiregulin | -0.0182813 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0182012 |
| TMEM45B | transmembrane protein 45B | -0.0180668 |
| CFB | complement factor B | -0.0179374 |
| NTN4 | netrin 4 | -0.0178355 |
| STK4 | serine/threonine kinase 4 | -0.0177254 |
| MYO1B | myosin IB | -0.017604 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0176004 |
| PTK2B | protein tyrosine kinase 2 beta | -0.0174716 |
| NABP1 | nucleic acid binding protein 1 | -0.0173662 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0168652 |
| SRPK1 | SRSF protein kinase 1 | -0.0164246 |
| SF1 | splicing factor 1 | -0.0164211 |
| CD44 | CD44 molecule (Indian blood group) | -0.0163485 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0163226 |
| RGS6 | regulator of G-protein signaling 6 | -0.0160898 |
| CAB39 | calcium binding protein 39 | -0.0160787 |
| PRR11 | proline rich 11 | -0.0158391 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0157473 |
| IFNGR1 | interferon gamma receptor 1 | -0.0155306 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0153933 |
| MTSS1 | metastasis suppressor 1 | -0.0152722 |
| ASPH | aspartate beta-hydroxylase | -0.0152527 |
| STK17A | serine/threonine kinase 17a | -0.0152495 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0152145 |
| SETX | senataxin | -0.0151303 |
| STXBP1 | syntaxin binding protein 1 | -0.0150411 |
| OSMR | oncostatin M receptor | -0.0141428 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0139862 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0138904 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0136794 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0136473 |
| ZNF217 | zinc finger protein 217 | -0.0136369 |
| NPC1 | Niemann-Pick disease, type C1 | -0.013473 |
| MYO9B | myosin IXB | -0.0134666 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0132724 |
| RASA2 | RAS p21 protein activator 2 | -0.0130919 |
| ANXA2 | annexin A2 | -0.0130056 |
| IER3 | immediate early response 3 | -0.0130024 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0129347 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | -0.012922 |
