| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Levobupivacaine (hydrochloride) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Levobupivacaine (hydrochloride)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.118162 |
| NDRG1 | N-myc downstream regulated 1 | 0.101559 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0727935 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0551001 |
| CALR | calreticulin | 0.0548736 |
| NUP58 | nucleoporin 58 | 0.0489541 |
| CABIN1 | calcineurin binding protein 1 | 0.0488228 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0478006 |
| CALD1 | caldesmon 1 | 0.0463367 |
| COPA | coatomer protein complex, subunit alpha | 0.0454181 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0435358 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0405472 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0386502 |
| VEGFA | vascular endothelial growth factor A | 0.0382404 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0377871 |
| RPL3 | ribosomal protein L3 | 0.036835 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0344612 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0337053 |
| RACK1 | receptor for activated C kinase 1 | 0.0326758 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0307912 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0305754 |
| GDF15 | growth differentiation factor 15 | 0.0295996 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0294513 |
| CALU | calumenin | 0.029289 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0289927 |
| CCNL1 | cyclin L1 | 0.0289817 |
| POTEF | POTE ankyrin domain family, member F | 0.0289587 |
| CD109 | CD109 molecule | 0.028472 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0282994 |
| YBX1 | Y box binding protein 1 | 0.0270495 |
| EGR1 | early growth response 1 | 0.0264045 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0260791 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0260629 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0259913 |
| RNF145 | ring finger protein 145 | 0.0259235 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0256068 |
| MKRN1 | makorin ring finger protein 1 | 0.0253201 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.025227 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.025181 |
| DCAF8 | DDB1 and CUL4 associated factor 8 | 0.0251497 |
| RBM26 | RNA binding motif protein 26 | 0.0247425 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0247088 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.02432 |
| SET | SET nuclear proto-oncogene | 0.0242899 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0242138 |
| TPM3 | tropomyosin 3 | 0.0241008 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0240486 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0236517 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0236054 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0231985 |
| CLIC4 | chloride intracellular channel 4 | 0.0231422 |
| FLNA | filamin A, alpha | 0.0228962 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0228033 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0225208 |
| CTBP2 | C-terminal binding protein 2 | 0.0223591 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0223069 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0222846 |
| TPR | translocated promoter region, nuclear basket protein | 0.022248 |
| CUX1 | cut-like homeobox 1 | 0.0222359 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0221425 |
| MYO5A | myosin VA (heavy chain 12, myoxin) | 0.0220979 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0220372 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0218816 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0218301 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0217194 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0216223 |
| SERINC3 | serine incorporator 3 | 0.0213769 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0212258 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | 0.0210144 |
| SNX13 | sorting nexin 13 | 0.0204435 |
| SEPTIN9 | septin 9 | 0.0197717 |
| SCARB1 | scavenger receptor class B, member 1 | 0.0195002 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0194079 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0193819 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0193292 |
| GPATCH2L | G patch domain containing 2-like | 0.0191376 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0191369 |
| CUL3 | cullin 3 | 0.019057 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0190311 |
| VMP1 | vacuole membrane protein 1 | 0.0188399 |
| RBM39 | RNA binding motif protein 39 | 0.0187123 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0187008 |
| HDAC9 | histone deacetylase 9 | 0.0186647 |
| FBXO42 | F-box protein 42 | 0.0185468 |
| SETD5 | SET domain containing 5 | 0.0184005 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0183483 |
| MRTFA | myocardin related transcription factor A | 0.0182951 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0181616 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0179508 |
| WDR43 | WD repeat domain 43 | 0.0177391 |
| SETBP1 | SET binding protein 1 | 0.0177162 |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) | 0.0176505 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0176374 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0175375 |
| FAM91A1 | family with sequence similarity 91, member A1 | 0.0174817 |
| RAD51B | RAD51 paralog B | 0.0174809 |
| BPNT2 | 3'(2'), 5'-bisphosphate nucleotidase 2 | 0.0174002 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0173898 |
| PTK2 | protein tyrosine kinase 2 | 0.0173651 |
| ATP6AP2 | ATPase, H+ transporting, lysosomal accessory protein 2 | 0.0173584 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.347209 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.208405 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.140992 |
| VIM | vimentin | -0.138502 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.133835 |
| GPC6 | glypican 6 | -0.120107 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.108491 |
| TNNC1 | troponin C type 1 (slow) | -0.0900832 |
| IER3 | immediate early response 3 | -0.0752042 |
| NLGN1 | neuroligin 1 | -0.0691938 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0618131 |
| MT2A | metallothionein 2A | -0.0595148 |
| FRMD4A | FERM domain containing 4A | -0.0584945 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0564507 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0547095 |
| TMSB10 | thymosin beta 10 | -0.0528772 |
| HLA-B | major histocompatibility complex, class I, B | -0.0528509 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0514202 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0503624 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0468202 |
| RTN4 | reticulon 4 | -0.0463599 |
| ACTG1 | actin gamma 1 | -0.046281 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0448041 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0439 |
| PCDH7 | protocadherin 7 | -0.0428698 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0403583 |
| MT1X | metallothionein 1X | -0.0398791 |
| IFRD1 | interferon-related developmental regulator 1 | -0.039183 |
| FMN1 | formin 1 | -0.037993 |
| ASPH | aspartate beta-hydroxylase | -0.037445 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0372643 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0370491 |
| PDE10A | phosphodiesterase 10A | -0.0356886 |
| SMYD3 | SET and MYND domain containing 3 | -0.0355116 |
| FBXO32 | F-box protein 32 | -0.0348906 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0343582 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0329068 |
| NPR2 | natriuretic peptide receptor 2 | -0.0327204 |
| A2M | alpha-2-macroglobulin | -0.0317636 |
| RRBP1 | ribosome binding protein 1 | -0.0310066 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0295279 |
| S100A6 | S100 calcium binding protein A6 | -0.0293689 |
| OSMR | oncostatin M receptor | -0.029362 |
| SFTPA2 | surfactant protein A2 | -0.0293201 |
| MACROD2 | MACRO domain containing 2 | -0.0288412 |
| OGA | O-GlcNAcase | -0.028643 |
| ANXA2 | annexin A2 | -0.0284621 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0282485 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0278488 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0275094 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0265858 |
| APP | amyloid beta (A4) precursor protein | -0.0262978 |
| PRELID2 | PRELI domain containing 2 | -0.0261408 |
| AHNAK | AHNAK nucleoprotein | -0.0260651 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0257104 |
| NHSL1 | NHS-like 1 | -0.0255377 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.0254706 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0251417 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.024858 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0246352 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0241968 |
| ATXN1 | ataxin 1 | -0.0239986 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0233167 |
| TMEM263 | transmembrane protein 263 | -0.0232981 |
| RPLP1 | ribosomal protein, large, P1 | -0.0232664 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0230356 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0226458 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0225452 |
| ZNF292 | zinc finger protein 292 | -0.0221735 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0221533 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.0220347 |
| S100A10 | S100 calcium binding protein A10 | -0.0219686 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0214654 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0210103 |
| RHOJ | ras homolog family member J | -0.0208415 |
| TRIM9 | tripartite motif containing 9 | -0.0207041 |
| FN1 | fibronectin 1 | -0.0206778 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | -0.0204418 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0204115 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0203451 |
| ZNF608 | zinc finger protein 608 | -0.0203361 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0203359 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0202954 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | -0.0201348 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0200686 |
| AFAP1 | actin filament associated protein 1 | -0.0200418 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0198072 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0196032 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0196032 |
| PHF20 | PHD finger protein 20 | -0.0195879 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0195023 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0194821 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0190189 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0190124 |
| INSIG1 | insulin induced gene 1 | -0.0188619 |
| RNF24 | ring finger protein 24 | -0.018814 |
| PGK1 | phosphoglycerate kinase 1 | -0.0187804 |
| SDC2 | syndecan 2 | -0.0186686 |
| RHEB | Ras homolog enriched in brain | -0.0186401 |
| ABI2 | abl-interactor 2 | -0.0184411 |
