| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Levobupivacaine (hydrochloride) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Levobupivacaine (hydrochloride)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0602887 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0595218 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0498239 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0445373 |
| VEGFA | vascular endothelial growth factor A | 0.0426406 |
| FMN1 | formin 1 | 0.0394859 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0389602 |
| NREP | neuronal regeneration related protein | 0.0380184 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0355948 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0348218 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0342512 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0325047 |
| PTEN | phosphatase and tensin homolog | 0.0321692 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0318365 |
| GPC5 | glypican 5 | 0.0317581 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0316842 |
| LSAMP | limbic system-associated membrane protein | 0.0315722 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0291653 |
| RACK1 | receptor for activated C kinase 1 | 0.0291056 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0272797 |
| ASPH | aspartate beta-hydroxylase | 0.0272651 |
| CENPF | centromere protein F, 350/400kDa | 0.0260492 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.026045 |
| FRMD4A | FERM domain containing 4A | 0.0248291 |
| DPH6 | diphthamine biosynthesis 6 | 0.0244921 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0238441 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.0233413 |
| KIAA1217 | KIAA1217 | 0.0220202 |
| RNF213 | ring finger protein 213 | 0.021902 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.021295 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0208157 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0206128 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0202363 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0198202 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0198074 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0197669 |
| SET | SET nuclear proto-oncogene | 0.0194684 |
| MEF2A | myocyte enhancer factor 2A | 0.0190534 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0187046 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0182299 |
| PGM3 | phosphoglucomutase 3 | 0.017894 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.017848 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0177891 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0177811 |
| ZNF638 | zinc finger protein 638 | 0.0177661 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0177539 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0172656 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0170964 |
| ZZZ3 | zinc finger, ZZ-type containing 3 | 0.0169688 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0169302 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0167249 |
| AHR | aryl hydrocarbon receptor | 0.0167222 |
| PCDH11Y | protocadherin 11 Y-linked | 0.0165804 |
| HDAC4 | histone deacetylase 4 | 0.0164898 |
| ATM | ATM serine/threonine kinase | 0.0164482 |
| DST | dystonin | 0.0164427 |
| MCL1 | myeloid cell leukemia 1 | 0.0164218 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0163434 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0162291 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0162223 |
| RBMX | RNA binding motif protein, X-linked | 0.0161959 |
| STK38L | serine/threonine kinase 38 like | 0.0159051 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0158866 |
| GPATCH2L | G patch domain containing 2-like | 0.0158498 |
| FOSL2 | FOS-like antigen 2 | 0.015797 |
| DIAPH2 | diaphanous-related formin 2 | 0.0157609 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0156373 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0155359 |
| TPM3 | tropomyosin 3 | 0.0154532 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0154299 |
| NBAS | neuroblastoma amplified sequence | 0.0154062 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0153636 |
| ZNF148 | zinc finger protein 148 | 0.0152722 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0151778 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | 0.015083 |
| CEP250 | centrosomal protein 250kDa | 0.0150725 |
| SRP68 | signal recognition particle 68kDa | 0.0150127 |
| PHF3 | PHD finger protein 3 | 0.0150065 |
| FNDC3B | fibronectin type III domain containing 3B | 0.014932 |
| ERGIC2 | ERGIC and golgi 2 | 0.0149074 |
| NRDC | nardilysin convertase | 0.014864 |
| RGS4 | regulator of G-protein signaling 4 | 0.0148444 |
| DHX40 | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 0.0146064 |
| RNF150 | ring finger protein 150 | 0.0145098 |
| PHF21A | PHD finger protein 21A | 0.0144533 |
| ARRDC3 | arrestin domain containing 3 | 0.0144322 |
| ANGPT1 | angiopoietin 1 | 0.014266 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | 0.0142606 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0142521 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.014184 |
| ENO1 | enolase 1, (alpha) | 0.0141365 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0140751 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0140414 |
| OSMR | oncostatin M receptor | 0.0140348 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0139447 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.013924 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0137758 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.013742 |
| YBX1 | Y box binding protein 1 | 0.0136957 |
| HOMER1 | homer scaffolding protein 1 | 0.0136199 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.324706 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.171332 |
| PTMA | prothymosin, alpha | -0.103956 |
| COL1A1 | collagen, type I, alpha 1 | -0.0611584 |
| VIM | vimentin | -0.0588751 |
| ACTG1 | actin gamma 1 | -0.0525972 |
| TMSB10 | thymosin beta 10 | -0.0515582 |
| RPLP1 | ribosomal protein, large, P1 | -0.048979 |
| HELZ | helicase with zinc finger | -0.048919 |
| RPL35A | ribosomal protein L35a | -0.0450919 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0435741 |
| RPS24 | ribosomal protein S24 | -0.0435065 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0424468 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.042352 |
| RPS6 | ribosomal protein S6 | -0.0417354 |
| RPL38 | ribosomal protein L38 | -0.0397398 |
| RPL19 | ribosomal protein L19 | -0.0397357 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0394221 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0378615 |
| ANXA2 | annexin A2 | -0.036916 |
| IER3 | immediate early response 3 | -0.0364512 |
| FTL | ferritin, light polypeptide | -0.0364323 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0361164 |
| SYT1 | synaptotagmin I | -0.0359808 |
| RPS19 | ribosomal protein S19 | -0.035211 |
| CCND1 | cyclin D1 | -0.0351983 |
| RPL23 | ribosomal protein L23 | -0.033744 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0336514 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0336449 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0331414 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0321575 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0321333 |
| MAP1B | microtubule-associated protein 1B | -0.0318669 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0316804 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0299225 |
| HIP1 | huntingtin interacting protein 1 | -0.0298881 |
| RPL34 | ribosomal protein L34 | -0.0288508 |
| FNBP1 | formin binding protein 1 | -0.0287048 |
| MED13 | mediator complex subunit 13 | -0.0282497 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0282128 |
| H3-3B | H3.3 histone B | -0.0280188 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0276371 |
| NF1 | neurofibromin 1 | -0.0270471 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0268447 |
| FOXK2 | forkhead box K2 | -0.0268175 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.0261539 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0259178 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0251353 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0247483 |
| GNAS | GNAS complex locus | -0.0246406 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0243918 |
| RPL32 | ribosomal protein L32 | -0.024175 |
| RPS11 | ribosomal protein S11 | -0.0241067 |
| KPNB1 | karyopherin (importin) beta 1 | -0.024012 |
| QKI | QKI, KH domain containing, RNA binding | -0.023964 |
| PKM | pyruvate kinase, muscle | -0.0238751 |
| NRG1 | neuregulin 1 | -0.0236831 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0233878 |
| MYO6 | myosin VI | -0.0233509 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0226855 |
| APP | amyloid beta (A4) precursor protein | -0.022573 |
| COL3A1 | collagen, type III, alpha 1 | -0.0224654 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0224178 |
| OGA | O-GlcNAcase | -0.0223103 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0218131 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.021806 |
| CADM2 | cell adhesion molecule 2 | -0.0217982 |
| SETD5 | SET domain containing 5 | -0.021723 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0216553 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0207291 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0207047 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0207013 |
| RPS14 | ribosomal protein S14 | -0.0206254 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0206158 |
| AOPEP | aminopeptidase O (putative) | -0.0206138 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.0205829 |
| RTN4 | reticulon 4 | -0.0204591 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0203293 |
| RPL31 | ribosomal protein L31 | -0.0202924 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0201946 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0201391 |
| SP100 | SP100 nuclear antigen | -0.0200183 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0199756 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0198538 |
| LMNA | lamin A/C | -0.0197234 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0196745 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0195936 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0195275 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0194768 |
| NEK7 | NIMA-related kinase 7 | -0.0194104 |
| RPS3 | ribosomal protein S3 | -0.0193744 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0192967 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0192734 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0190498 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0189177 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.018745 |
| GPATCH8 | G patch domain containing 8 | -0.0186577 |
| RAD21 | RAD21 homolog (S. pombe) | -0.018594 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.018575 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0184532 |
