| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Levobupivacaine (hydrochloride) perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Levobupivacaine (hydrochloride)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.194221 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.066248 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0567445 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0564296 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 | 0.0554709 |
| GOLGB1 | golgin B1 | 0.0553412 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0537371 |
| CANX | calnexin | 0.0527989 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0516714 |
| RNF43 | ring finger protein 43 | 0.0483959 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0463322 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0442161 |
| RAD51B | RAD51 paralog B | 0.0441186 |
| CALR | calreticulin | 0.0440919 |
| NCKAP5 | NCK-associated protein 5 | 0.0428841 |
| HDLBP | high density lipoprotein binding protein | 0.0425622 |
| HYOU1 | hypoxia up-regulated 1 | 0.0423247 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0421466 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0411642 |
| TXNIP | thioredoxin interacting protein | 0.0405719 |
| PRELID2 | PRELI domain containing 2 | 0.0394051 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0386872 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0385799 |
| PHF3 | PHD finger protein 3 | 0.0385223 |
| CALU | calumenin | 0.0379266 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0378937 |
| MEIS2 | Meis homeobox 2 | 0.0373049 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0373024 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0365006 |
| RACK1 | receptor for activated C kinase 1 | 0.0354908 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0354604 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | 0.0352516 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.035112 |
| MPHOSPH8 | M-phase phosphoprotein 8 | 0.0348604 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0348159 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0346494 |
| GPATCH8 | G patch domain containing 8 | 0.0345363 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0342593 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0340119 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0337086 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0327874 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0324471 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0324463 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0311731 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0308695 |
| PTEN | phosphatase and tensin homolog | 0.0304254 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0300511 |
| DSPP | dentin sialophosphoprotein | 0.0299705 |
| IFNGR1 | interferon gamma receptor 1 | 0.0296661 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0292993 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0291033 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0288358 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0284355 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0283694 |
| ATM | ATM serine/threonine kinase | 0.0283445 |
| VEGFA | vascular endothelial growth factor A | 0.028205 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0279678 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0279582 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0278106 |
| NUCB2 | nucleobindin 2 | 0.0276884 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0273877 |
| DIAPH3 | diaphanous-related formin 3 | 0.027235 |
| MICU1 | mitochondrial calcium uptake 1 | 0.0272038 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0269131 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0267558 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0265258 |
| EHF | ets homologous factor | 0.0263859 |
| IL20RA | interleukin 20 receptor, alpha | 0.0263123 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0260322 |
| TAOK3 | TAO kinase 3 | 0.0257724 |
| KMT5B | lysine methyltransferase 5B | 0.0256832 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0255744 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0253559 |
| GOLGA2 | golgin A2 | 0.0251354 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0249305 |
| GOLGA4 | golgin A4 | 0.0248354 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0247997 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0246753 |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 0.0244394 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.024362 |
| RPL12 | ribosomal protein L12 | 0.0241046 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0236215 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0235531 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0234884 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0234668 |
| HBS1L | HBS1-like translational GTPase | 0.0234097 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0234053 |
| RASSF6 | Ras association (RalGDS/AF-6) domain family member 6 | 0.0232682 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0230197 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0228867 |
| TMF1 | TATA element modulatory factor 1 | 0.0226485 |
| IRF1 | interferon regulatory factor 1 | 0.0226342 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0225779 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease | 0.0223328 |
| PHF21A | PHD finger protein 21A | 0.0222708 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0220854 |
| WDR26 | WD repeat domain 26 | 0.0220233 |
| AHNAK | AHNAK nucleoprotein | 0.0219894 |
| ARRDC3 | arrestin domain containing 3 | 0.0219317 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0216646 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RNF213 | ring finger protein 213 | -0.152016 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.124694 |
| EGR1 | early growth response 1 | -0.105556 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.102248 |
| MX2 | MX dynamin-like GTPase 2 | -0.100071 |
| ANXA2 | annexin A2 | -0.0960375 |
| AREG | amphiregulin | -0.0949099 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0937522 |
| RIGI | RNA sensor RIG-I | -0.0923288 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0830526 |
| SP100 | SP100 nuclear antigen | -0.0809807 |
| VCL | vinculin | -0.0802626 |
| ERBIN | erbb2 interacting protein | -0.0780056 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0767359 |
| TJP1 | tight junction protein 1 | -0.0765901 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0728726 |
| PERP | PERP, TP53 apoptosis effector | -0.0724773 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.071035 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0703848 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0701091 |
| ITGA6 | integrin, alpha 6 | -0.0694932 |
| PTMA | prothymosin, alpha | -0.0692258 |
| LMO7 | LIM domain 7 | -0.0673985 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0652116 |
| MX1 | MX dynamin-like GTPase 1 | -0.0636585 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0628416 |
| NPSR1 | neuropeptide S receptor 1 | -0.061046 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.057402 |
| ACTG1 | actin gamma 1 | -0.0556443 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0534226 |
| B2M | beta-2-microglobulin | -0.0530073 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0518679 |
| MYO1E | myosin IE | -0.0510024 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0495832 |
| BCL2L1 | BCL2-like 1 | -0.0491743 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0489733 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0486766 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0480226 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0477466 |
| FNDC3B | fibronectin type III domain containing 3B | -0.047255 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0461348 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0441494 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0438227 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.043761 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.042489 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0423885 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0423481 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0419743 |
| LYZ | lysozyme | -0.0419275 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0415827 |
| ETV6 | ets variant 6 | -0.0415517 |
| TM4SF19 | transmembrane 4 L six family member 19 | -0.041066 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0403588 |
| XAF1 | XIAP associated factor 1 | -0.0400729 |
| FTL | ferritin, light polypeptide | -0.0397658 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0379787 |
| KLF6 | Kruppel-like factor 6 | -0.0378649 |
| POTEF | POTE ankyrin domain family, member F | -0.037678 |
| SPATA13 | spermatogenesis associated 13 | -0.0375085 |
| VMP1 | vacuole membrane protein 1 | -0.0374984 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0359302 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0354727 |
| PLSCR1 | phospholipid scramblase 1 | -0.0337503 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0334557 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0324126 |
| EFNB2 | ephrin-B2 | -0.0320463 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0316564 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0313742 |
| STK24 | serine/threonine kinase 24 | -0.0310228 |
| ZNF292 | zinc finger protein 292 | -0.0309159 |
| MUC20 | mucin 20, cell surface associated | -0.0305673 |
| CLOCK | clock circadian regulator | -0.0303866 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0302721 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0299097 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0294264 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0291557 |
| EZR | ezrin | -0.0291344 |
| PMP22 | peripheral myelin protein 22 | -0.0290749 |
| CLDN4 | claudin 4 | -0.0287053 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0286331 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | -0.0283923 |
| ANXA11 | annexin A11 | -0.0283459 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0280738 |
| S100A6 | S100 calcium binding protein A6 | -0.0277112 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.0276871 |
| NABP1 | nucleic acid binding protein 1 | -0.0275893 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0275081 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0274027 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0270355 |
| SPAG9 | sperm associated antigen 9 | -0.0268656 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0267496 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0267288 |
| CMPK2 | cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial | -0.02662 |
| LAMA4 | laminin, alpha 4 | -0.0265706 |
| OXSR1 | oxidative stress responsive 1 | -0.0265269 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0264859 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.0263686 |
| MT2A | metallothionein 2A | -0.0262727 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.0262297 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0260333 |
