| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Levobupivacaine (hydrochloride) perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Levobupivacaine (hydrochloride)_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.193507 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.131694 |
| NDRG1 | N-myc downstream regulated 1 | 0.127122 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.121664 |
| STC1 | stanniocalcin 1 | 0.116355 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.110643 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0774216 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0729096 |
| SMAD3 | SMAD family member 3 | 0.0710905 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0701926 |
| CANX | calnexin | 0.0677192 |
| YBX1 | Y box binding protein 1 | 0.0624992 |
| ATP13A3 | ATPase type 13A3 | 0.0601583 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0567028 |
| RACK1 | receptor for activated C kinase 1 | 0.0563759 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0563513 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0543556 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0541418 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | 0.0525205 |
| TNNC1 | troponin C type 1 (slow) | 0.0510393 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0501776 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0494707 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0468439 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0460445 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0448743 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0446914 |
| GOLGA4 | golgin A4 | 0.0446305 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0440001 |
| INHBA | inhibin, beta A | 0.0436912 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0431599 |
| MAP1B | microtubule-associated protein 1B | 0.0425636 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0422927 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0414056 |
| TPM3 | tropomyosin 3 | 0.0408265 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0407312 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0401545 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0395837 |
| OSMR | oncostatin M receptor | 0.0386971 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0386962 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.038642 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0382081 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0372597 |
| ANO6 | anoctamin 6 | 0.0369354 |
| GOLGB1 | golgin B1 | 0.0367838 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0366977 |
| HJURP | Holliday junction recognition protein | 0.0363694 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0359263 |
| LRRC49 | leucine rich repeat containing 49 | 0.0355875 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0355115 |
| SBF2 | SET binding factor 2 | 0.035335 |
| MSN | moesin | 0.0352263 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0350661 |
| MORF4L2 | mortality factor 4 like 2 | 0.0346051 |
| PRRC2C | proline-rich coiled-coil 2C | 0.03439 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.034294 |
| MKI67 | marker of proliferation Ki-67 | 0.0341342 |
| GLIS3 | GLIS family zinc finger 3 | 0.0341187 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0334647 |
| RASA2 | RAS p21 protein activator 2 | 0.0334533 |
| NF1 | neurofibromin 1 | 0.0334326 |
| AHNAK | AHNAK nucleoprotein | 0.032276 |
| ANXA5 | annexin A5 | 0.0322126 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0320036 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0318838 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0318609 |
| CALR | calreticulin | 0.031622 |
| TXNRD1 | thioredoxin reductase 1 | 0.0315313 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0315308 |
| FAM13A | family with sequence similarity 13, member A | 0.0314337 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0306549 |
| CD59 | CD59 molecule, complement regulatory protein | 0.030231 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0300905 |
| HDLBP | high density lipoprotein binding protein | 0.0300311 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0298189 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0295792 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0293407 |
| FOXJ3 | forkhead box J3 | 0.0292716 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0291175 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0290837 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0290483 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0287884 |
| SEPTIN10 | septin 10 | 0.0286715 |
| ZNF841 | zinc finger protein 841 | 0.0282795 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0281329 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0281039 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0280019 |
| LOC112694756 | uncharaterized LOC112694756 | 0.027866 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0277423 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.027736 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0276587 |
| YME1L1 | YME1-like 1 ATPase | 0.0276271 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0272481 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0272237 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0270533 |
| GOLGA2 | golgin A2 | 0.0267818 |
| CALU | calumenin | 0.0267691 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0266185 |
| WDR26 | WD repeat domain 26 | 0.0265164 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0262927 |
| RLF | rearranged L-myc fusion | 0.0262289 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.11271 |
| MT2A | metallothionein 2A | -0.0962296 |
| TMSB10 | thymosin beta 10 | -0.09521 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0825507 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0816631 |
| NLGN1 | neuroligin 1 | -0.0754721 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0747489 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0637258 |
| FN1 | fibronectin 1 | -0.0590058 |
| FTL | ferritin, light polypeptide | -0.0464125 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0449241 |
| NAV1 | neuron navigator 1 | -0.0432456 |
| HLA-B | major histocompatibility complex, class I, B | -0.0420317 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0405739 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.040234 |
| AUTS2 | autism susceptibility candidate 2 | -0.0383655 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0382602 |
| VCL | vinculin | -0.0381314 |
| HLA-A | major histocompatibility complex, class I, A | -0.0373662 |
| B2M | beta-2-microglobulin | -0.0372259 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0371033 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0367577 |
| IGF2 | insulin-like growth factor 2 | -0.0350057 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0343499 |
| HIP1 | huntingtin interacting protein 1 | -0.0339981 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0336251 |
| MT1X | metallothionein 1X | -0.0332184 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0315714 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0306937 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0304962 |
| AHR | aryl hydrocarbon receptor | -0.0302833 |
| RPL35A | ribosomal protein L35a | -0.0302749 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0301496 |
| GLCCI1 | glucocorticoid induced 1 | -0.0293039 |
| EGR1 | early growth response 1 | -0.0289334 |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) | -0.0286318 |
| OXR1 | oxidation resistance 1 | -0.0286012 |
| HS6ST3 | heparan sulfate 6-O-sulfotransferase 3 | -0.0285507 |
| COL5A1 | collagen, type V, alpha 1 | -0.0281265 |
| POTEF | POTE ankyrin domain family, member F | -0.0280839 |
| PTCHD4 | patched domain containing 4 | -0.0279949 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0273099 |
| RIGI | RNA sensor RIG-I | -0.026985 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0266967 |
| MEIS2 | Meis homeobox 2 | -0.0263321 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0261519 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0261188 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0261153 |
| PTK2 | protein tyrosine kinase 2 | -0.0260334 |
| XYLT1 | xylosyltransferase I | -0.0259011 |
| SYT1 | synaptotagmin I | -0.0254709 |
| FNIP1 | folliculin interacting protein 1 | -0.0251984 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0249403 |
| RUNX1 | runt-related transcription factor 1 | -0.0248685 |
| SQSTM1 | sequestosome 1 | -0.0247441 |
| NRXN3 | neurexin 3 | -0.0246728 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.024322 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0241876 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0241175 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0233064 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0232696 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0228265 |
| LYPD6B | LY6/PLAUR domain containing 6B | -0.0228069 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0227772 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0227705 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0226599 |
| USP34 | ubiquitin specific peptidase 34 | -0.0226155 |
| RPS6 | ribosomal protein S6 | -0.0222455 |
| PRKCA | protein kinase C, alpha | -0.0219361 |
| TCF12 | transcription factor 12 | -0.0219245 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0216096 |
| FGF13 | fibroblast growth factor 13 | -0.0208022 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0207885 |
| ZNF804A | zinc finger protein 804A | -0.0206808 |
| IFI44 | interferon-induced protein 44 | -0.0206569 |
| DTNA | dystrobrevin, alpha | -0.020431 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0204175 |
| CEP128 | centrosomal protein 128kDa | -0.0203097 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.0200203 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0198922 |
| PRSS23 | protease, serine, 23 | -0.0198076 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.0197978 |
| MRC2 | mannose receptor, C type 2 | -0.0197462 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0196778 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0195407 |
| CUX1 | cut-like homeobox 1 | -0.0195111 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.019451 |
| TENM3 | teneurin transmembrane protein 3 | -0.0193254 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.0191382 |
| PRELID2 | PRELI domain containing 2 | -0.0190752 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0188613 |
| PFN1 | profilin 1 | -0.0188549 |
| FAM219A | family with sequence similarity 219, member A | -0.018608 |
| PALLD | palladin, cytoskeletal associated protein | -0.0185146 |
| RPS19 | ribosomal protein S19 | -0.0183687 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0182844 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) | -0.0182557 |
| PCYT1A | phosphate cytidylyltransferase 1, choline, alpha | -0.0177482 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0177267 |
| RPL37A | ribosomal protein L37a | -0.0176542 |
